Completion
by BSA only
Project Assessment I.D.:
If updated, date of first consent:
Consent date for this version:
CL
with derogation ☐
FORM: BA1
GM Class
BIOLOGICAL AGENTS (including GM) & MATERIALS:
PROJECT REGISTRATION & RISK ASSESSMENT
Please note the following:


Form Use: to register and risk assess projects involving the use of Biological Agents (including Genetically
Modified Micro-Organisms), or materials (such as cells and tissues) that may be contaminated with these
agents. The assessment should identify all significant hazards and risks associated with
Biological Agents: refers to any microorganism, cell culture, or endoparasite that may cause infection, allergy,
toxicity or otherwise cause a hazard to human & / or animal health




Consent / Approval: work must not commence until the Principal Investigator has received consent from
the Biological Safety Adviser (BSA) / Biological Agents Safety Committee:
Responsibility: it is the responsibility of the person directing the research (i.e. the Principal Investigator)
to ensure that all these requirements are complied with and that the risk assessment remains valid.
Local Rules / Code of Practice: written protocols (Local Rules / Code of Practice (CoP) or Standard
Operating Procedures (SOPs)), containing details of the key working practices to be followed, must
accompany the assessment at submission for work requiring CL2 or above.
Changes: any significant changes to the work activity must be notified to the BSOs. All changes must be
incorporated within an amended version of this form as well as within the Local Rules / Code of Practice
plus details of what has been changed recorded within the risk assessment change control form.
Person(s) responsible for this GM activity (Principle Investigator):
Name(s):
Department:
Person conducting this assessment (if different from above):
Name:
Position:
Department:
Date:
The Project Activity:
Project Title (e.g. title used in grant application):
Location(s) of work activity
Department(s):
List all areas to be used e.g. the main
lab, shared incubator rooms, shared
storage facilities
Building(s) and Room(s):
The following declaration must be completed by the PI responsible for this project
☐ Information contained in this assessment is accurate and comprehensive
☐ All work will remain within the boundaries of this Project Registration / Assessment
☐ All significant changes to this work activity will be reassessed and the changes submitted to the BSA before
those changes are made to the work
☐ All workers associated with this work will be given appropriate training and where necessary, their
competency assessed and recorded
☐ If necessary, all workers will be enrolled with Occupational Health for health clearance before work starts
COLOUR SCHEME GUIDANCE FOR THIS FORM:
Blue fill =
required for all work
Pink fill = tissues, cells, etc
specific
Page 1 of 12
Green fill - non-GM biological
agents specific
Orange fill – GMM specific
Version: 1
Part 1 (Registration): To be Completed for all Work Activities
1. INTRODUCTION
This information provides a useful background and puts the work into context. Brief yet clear outline only please- provides the
reviewer a better understanding of the aims of the work. For Q1.2, cover as much of your activities with a particular agent or
material as possible within this form. The intention of this Project Registration is primarily to outline the scope of the proposed
works, before risk assessing specific procedures in the next section.
1.1 Background and aim(s) of the project
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1.2 Description of experimental procedures (outline the scope of the project by describing the different laboratory procedures
to be used)
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2. NATURE OF THE WORK AND HAZARD IDENTIFICATION
This information provides details of the nature of the biological agent(s) / material(s) and an indication of the potential harm it could cause
TISSUES, CELLS, BODY FLUIDS OR EXCRETA
2.1
2.2
If human or animal tissues, cells, body fluids or excreta will NOT be used tick here ☐ & proceed to Q2.9
If GM cell cultures / lines are used, complete relevant parts of this section & the GM section below
2.3
List all the tissues, cells, body fluids or excreta to be
used (species, type, where obtained)
Details on the source of the material must be included
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2.4
Describe what infectious agents this material has
been screened for
Will any clinical history or veterinary screening (if
relevant) be provided?
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2.5
If yes, detail what this will include:
Yes ☐
No ☐
N/R ☐
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If yes, will a policy of rejection of samples from
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diseased donors be adopted? Explain:
If yes and for human material, how will the
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information be disseminated in the course of the
project?
If yes, and for human material, will this information be
Yes ☐
No ☐
N/R ☐
anonomised?
2.6 What is the likelihood of infection of
Medium risk ☐ High risk ☐
None ☐
Low risk ☐
any of this material? Consider the
If medium or high risk of infection go to
If none or low risk
worst case if multiple tissues, cells, etc next question
proceed to Question 2.10
are used
2.7
2.8
2.9
If medium or high risk of infection
name and classify the biological
agents this material could be infected
with
Describe the type and severity of the
disease that can be caused to humans
or animals by each of the agents that
could be present
Do any of the materials listed require
a licence or a permit before work
commences?
Tissue, cell, fluids or
excreta
Name of agent
Human / Animal Pathogen
classification (HG 1-4)
Click here to enter
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text.
text.
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For example, IAPPO1, SAPO, DEFRA, or FERA licences? If yes, state which ones.
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Yes ☐
2.10 Does the work require ethical
approval?
Page 2 of 12
No ☐
Version: 1
NON-GM BIOLOGICAL AGENTS
2.11 If non-Genetically-Modified Biological Agents will NOT be used tick here ☐ and proceed to Q2.15
2.12 Non-GM biological agents
used:
Name of agent(s)
Strain(s)
Human / Animal
Pathogen Classification
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text.
2.13 Describe the type and severity of the disease that can Click here to enter text.
be caused to humans, animals or plants by each of
the agents, and if relevant, the particular strains in
use
2.14 Do any of the organisms listed require a licence or a permit before work commences
(e.g. SAPO, DEFRA, or FERA licences)?
Click here to enter
text.
GENETICALLY MODIFIED MICROORGANISMS
The term ‘microorganism’ means a microbiological entity, cellular or non-cellular, capable of replication or of
transferring genetic material- includes a virus, viroid and animal / plant cell cultures
2.15 If Genetically-Modified Micro-Organisms (GMMs) will NOT be used then tick here ☐ and proceed to Question 3.1
2.16 Provide an overview of the different types of GMM
that will be constructed. The scope and boundaries of
the work need to be made clear.
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2.17 List all recipient species & representative strains to
be used & their human / animal pathogen
classification (Hazard Groups 1-4)
Note: list recipient strains in generic terms e.g. K12
strains; list & assessment must be updated if new
vector systems significantly alters the hazard / risk
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2.18 Do any of the organisms listed require a licence or a
permit before work commences (e.g. SAPO, DEFRA,
or FERA licences)?
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2.19 List of vector systems to be used and their particular
functional properties
Note: list vector systems in generic terms; list &
assessment must be updated if new vector systems
significantly alters the hazard / risk
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2.20 List the names and functional properties of altered /
inserted genes
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2.21 Identify the most hazardous GMM(s) to be
constructed giving consideration both to human
health and the environment.
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3. DECLARATION:
To be completed in all cases
3.1 Are you confident that any non-GM organism, tissue,
cell, blood, body fluid or any component of any
GMM covered by this assessment presents no /
negligible risk to humans or the environment?
Further guidance
Yes ☐
No ☐
Tick here if you believe that this
project comprises work requiring only
Containment Level 1 (‘Class 1’
for GMM). The generic GM
assessment / controls for activities of
no/negligible risk to be applied. Part 2
does not need to be completed
Tick here if you believe that
Containment Level 2 (or
higher) is required and then
answer Q3.2 and proceed to
Part 2 & Q4.1 of this form
3.2 Do any of the materials contain pathogens or toxins
covered by the Anti-Terrorism (Crime and Security
Act)?
Choose an item.
If yes, then Section 4 must still be completed even if only CL1
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Version: 1
Part 2: Continuation Form for Use in Cases Where a Detailed Risk Assessment is Necessary
4. FURTHER DETAILED ASSESSMENT
Must be completed if Q3.1 was answered ‘NO’
TISSUES, CELLS, BODY FLUIDS OR EXCRETA
4.1 If human or animal tissues, cells, body fluids or excreta will NOT be used tick here ☐ and proceed to Q4.9
4.2 If GM cell cultures are used, complete relevant parts of this section & the GM section below
4.3 Will any culturing of the material described in Q2.3 take
place? If yes, describe which cell(s) will be cultured and
under what conditions.
Choose an item.
4.4 If culturing, could HIV permissive cells be present? If yes,
describe the cells and for how long these cultures will be
allowed to grow.
Choose an item.
4.5 If culturing, what is the maximum volume of culture
grown?
Per flask: Click here to enter text.
4.6 Will the tissues, cells, body fluids or excreta be
manipulated in any way that could result in the
concentration of any adventitious biological agent
present? If yes, explain.
Choose an item.
4.7 What will be the most hazardous procedure(s) involving
the use of this material that could cause exposure to
workers?
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4.8 Will any of the fluids, tissues or cells be donated by you
or your colleagues?
Choose an item.
Click here to enter text.
Click here to enter text.
Number of flasks: Click here to enter text.
Click here to enter text.
If yes, detail who will provide these
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N/R ☐
If yes, explain the special risks associated
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N/R ☐
If yes, provide justification for not using material from
another safer source e.g. National Blood Service
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If yes, how will confidentiality be assured?
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If yes, has written consent been obtained from the
donor?
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If yes, has Ethics Committee approval been obtained?
N/R ☐
N/R ☐
N/R ☐
Choose an item.
NON-GM BIOLOGICAL AGENTS
4.9
If non-Genetically-Modified Biological Agents will NOT be used tick here ☐ and proceed to Q4.15
4.10 Describe ALL the route(s)
Name of agent(s)
Route(s) of infection
Min. infectious dose
of infection (relevant to
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Click here to enter text.
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the lab setting) and the
minimum infectious
dose(s), if known
Per experiment: Click here to enter text.
4.11 What is the highest concentration and volume of
Total stored: Click here to enter text.
agent(s) to be worked with?
4.12 Are there any known drug resistances amongst
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the strains to be used? If yes, explain what these
are and the consequences
4.13 What forms of the agent will be used e.g. spores,
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Version: 1
vegetative forms and are there any issues over
the robustness of these particular forms e.g.
resistance to disinfectants or increased stability
on dry surfaces
4.14 What will be the most hazardous procedure(s)
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involving the use of this material that could cause
exposure to workers?
GENETICALLY MODIFIED MICROORGANISMS
The term ‘microorganism’ means a microbiological entity, cellular or non-cellular, capable of replication or of
transferring genetic material- includes a virus, viroid and animal / plant cell cultures
Please refer to the GM guidance sheet to assist in the completion of this section of the assessment
4.15 If GMMs will NOT be used then tick here ☐ and proceed to Q5
4.16 Identify any hazards to human health or to the
environment of the recipient microorganism(s)
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4.17 Identify any hazards to human health or to the
environment associated directly with the vector
system(s) in use
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For viral vectors consider the vectors mode of transmission,
disease symptoms, host range, and tissue tropism as well as
an indication as to whether vaccines or chemotherapeutic
agents are available. Identify any disabling mutations and
whether there is a possibility of any disabling mutations
being complemented or reverting.
4.18 Identify all of the known or potential hazards to
human health or the environment associated with all
the GMMs to be generated. It is important that the
boundaries of this project are clearly explained here.
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Consider a) whether the inserted gene encodes a
pathogenicity determinant, such as an adhesion, a
penetration factor or a surface component providing
resistance to host defence mechanisms; b) whether the
inserted gene encodes a surface component, envelope
protein or capsid protein that might bind to a different
receptor to that used by the recipient microorganism, and c)
whether the inserted DNA (or plasmid sequence) encodes
resistance to a drug or antibiotic that might be used for the
treatment of a laboratory-acquired infection.
4.19 Describe the likelihood and consequences of the
modifications being transferred to related
microorganisms
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4.20 Identify the most hazardous GMM(s) to be
constructed. What is the likelihood that, in the event
of exposure (humans / environment), the GMM could
actually cause harm?
Click here to enter text.
4.21 Describe ALL the potential route(s) of
infection (relevant to the laboratory
setting) of the GMM(s)
Name of agent
Route(s) of infection
Minimum infectious
dose
Click here to enter
Click here to enter
Click here to enter
text.
text.
text.
Per
experiment:
Click
here
to
enter
text.
4.22 What is the highest concentration and volume of the
Total
stored:
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here
to
enter
text.
GMM(s) to be worked with?
4.23 What will be the most hazardous procedure(s)
involving the use of this material that could cause
exposure to workers / the environment?
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5. RISK FACTORS AND CONTROL MEASURES
This section considers the nature of the work to identify factors that affect risk of exposure and selection of appropriate
measures to adequately control the risk. All questions must be answered and further details supplied when indicated.
NOTE that key working practices identified below must be documented in a Code of Practice (CoP) / Local Rules or
Standard Operating Procedure (SOP) for CL2 work or higher, or work covered by the Anti-Terrorism (Crime & Security) Act
Risk
If yes, how will it be controlled?
Reference any SOP, CoP or other written protocol providing details on usage,
training, decontamination, etc.
5.1 Will infectious
droplets or aerosols
be created, either
deliberately or by
accident?
Choose
an item.
A microbial safety cabinet (or isolator for in vivo work) must be used for
activities likely to generate potentially infectious aerosols or splashes. If
needed, state the type(s) and when it will be applied
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5.2 Will material be
transported within the
laboratory?
Choose
an item.
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For example, cultures being transported between the safety cabinet and the
incubator must be double contained so as to prevent spillage if dropped
5.3 Will the material be
transported locally on
campus but outside of
the laboratory?
5.4 Will this material be
shipped elsewhere in
the UK or abroad?
5.5 Will this material be
received from
elsewhere?
5.6 Will this material be
stored?
5.7 Will infectious
material be
centrifuged?
Choose
an item.
Click here to enter text.
For example, material transported from the primary laboratory to the BSF must
be double contained so as to prevent spillage if dropped, adequately labelled
and no gloves must be worn outside of the laboratory
Choose
an item.
If yes, provide details of material to be shipped and the packing
instructions to be followed Click here to enter text.
Choose
an item.
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Provide details of material to be received, how this will be arranged & what
steps will be taken to ensure that the material is correctly packaged. Further
guidance is available on the Safety website
Choose
an item.
Click here to enter text.
Provide details of how, where and in what this material will be stored. If stored
in Liquid Nitrogen describe the additional precautions in place
Choose
an item.
5.8 Are biological samples
to be cultured in an
incubator?
Choose
an item.
5.9 Are sharps to be used
at any stage during
this activity?
Choose
an item.
5.10
Are animals to be used
as part of this project?
Choose
an item.
If yes:
a) Will sealed rotors & buckets always be used? Click here to enter text.
b) Where will rotors / buckets be opened?
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c) Describe procedure to deal with leaks / spillages: Click here to enter text.
What type of incubator (e.g. shaking or static shelf) is this and describe the
measures to be used to prevent and contain any spillages
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Describe the sharps, justify their use and describe the precautions in place to
protect the user and others from injury
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What procedures will be undertaken?
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Where will this aspect of the work be undertaken? Click here to enter text.
Is shedding of biological agent or GMMs by the infected animals possible? Click
here to enter text.
If yes, detail routes of shedding, risk periods for such shedding and the
additional precautions required to control exposure Click here to enter text.
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Who will perform the inoculations/exposure of the animals?
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What training will they have received and where will this be recorded?
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Provide details on any additional training required for those handling these
animals Click here to enter text.
Provide details on any additional precautions necessary Click here to enter text.
5.11
Will a fermenter
be used to culture the
pathogen
Choose
an item.
What size and type is this and are any supplementary containment measures
required, for example, the use of a safety cabinet or spill tray? Click here to
enter text.
Where is this fermenter located and who is in charge of the area? Click here to
enter text.
5.12
Is there any stage
within the
experimental
procedures when the
infectious material is
inactivated (other
than for disposal)?
Choose
an item.
If yes, how will this be done and what will then happen to the material? Click
here to enter text.
5.13
For organisms
whose multiplication
involves a complex
life-cycle will the work
involve the
propagation of
organisms that are in
that life cycle that is
particularly
hazardous? E.g.
growth of infective
stages of parasites or
release
Choose
an item.
Click here to enter text.
5.14
Will lone working
take place for this
work activity?
Choose
an item.
If yes, how will the safety of those individuals engaged in higher risk activities
be monitored? Click here to enter text.
6. PERSONAL PROTECTION
All questions must be answered and further details supplied when indicated.
NOTE that key working practices identified below must be documented in a Code of Practice (CoP) / Local Rules or
Standard Operating Procedure (SOP) for CL2 or higher work, or work covered by the Anti-Terrorism (Crime & Security) Act
6.1 Are gloves necessary to protect
the worker (as opposed to the
work)?
Choose an item.
6.2 What type are these?
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6.3 Where will lab coats be stored and
what are the arrangements for
cleaning?
6.4 Is any other type of personal
protective equipment required
(e.g. safety glasses)?
If yes, provide details
Click here to enter text.
Click here to enter text.
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7. WASTE
All questions must be answered and further details supplied when indicated.
NOTE that waste disposal practices must be documented in a Code of Practice (CoP) / Local Rules or Standard Operating
Procedure (SOP) for CL2 or higher work, or work covered by the Anti-Terrorism (Crime & Security) Act
7.1 How will waste be treated prior to disposal?
(Note that all differently treated
wastes must be included e.g. if
some liquid is autoclaved, but
others not, then describe both)
Liquid waste
Treatment prior to disposal
Solid waste
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Other waste (specify): Click here
to enter text.
Click here to enter text.
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If liquid waste treated by disinfectant, how has this been validated (used according
to suppliers instructions / in-house validation (required for CL3 activities))?
Click here to enter text.
7.2 If waste is to be autoclaved confirm the following:
All cycles have been validated for the
Choose an item.
actual load types used
The successful completion of every
Choose an item.
load is checked prior to disposal?
7.3 How will liquid waste be disposed of?
To drain?
Choose an item.
As solid waste?
Choose an item.
Other (specify)?
Click here to enter text.
Choose an item.
7.4 How will solid waste be disposed of?
Categorisation
Colour code
Disposal Route
☐ Sharps
Yellow
Yellow sharps bin > autoclave
sterilisation if known or potentially
infected >clinical waste disposal
(incineration)
☐ Human body parts, organs including
blood bags and blood preserves and
excreta (unless identified as medium
or high risk or known infected in Q2.6
of this assessment in which case they
must be pre-treated before disposal)
Yellow
Yellow rigid one way sealed tissue
bins > clinical waste disposal
(incineration)
☐ Animal body carcasses or
recognisable parts (unless identified
as medium or high risk or known
infected in Q2.6 of this assessment in
which case they must be pre-treated
before disposal)
Yellow
Yellow rigid one way sealed tissue
bins > clinical waste disposal
(incineration)
☐ Potentially or known infected lab
wastes (including sharps) of Hazard
Group 2, GM Class 2, DEFRA Category
2 or higher, that have NOT been pre-
Special case – contact Biological
Safety Advisor
This is not a route of preference and
is subject to special requirements
* Human tissue waste must be placed
in separate containers from nonhuman waste and labelled ‘HTA
waste’
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treated before leaving site
☐ Infected or potentially infected lab
wastes that have been pre-treated
before leaving site
Yellow / Orange
Disinfection or sterilisation in the
laboratory suite > yellow/orange
clinical waste bags > clinical waste
disposal
☐ Infected or potentially infected
animal or human body parts, organs or
excreta that have been pre-treated
before leaving site
Yellow
Disinfection or sterilisation in the
laboratory suite >yellow one way
sealed tissue bins > clinical waste
disposal (incineration)
* Human tissue waste must be placed
in separate containers from nonhuman waste and labelled ‘HTA
waste’
☐ Packaging material that has been
used for the importation of animal
products subject to Defra licences
Yellow
yellow clinical waste bags > clinical
waste disposal (incineration or
alternative treatment as described in
the licence
8. MAINTENANCE OF CONTROL MEASURES
Control measures (e.g. microbial safety cabinets (MSC) / autoclaves) must be maintained and work properly. Simple
visual inspection may be appropriate, or more detailed examinations and testing may be needed e.g. MSCs need testing
at least every 12 months (or every 6 months for high hazard bio-agents). Specify what, if any, checks on control
measures are required and state the frequency of inspection required.
Click here to enter text.
9. TRAINING
Describe the training that will be given to all those affected (directly or indirectly) by the work activity. Instruction
should include the ‘Local Rules’ or ‘Local Codes of Practice’ which focus on the working instructions to be followed by all
persons involved in the work activity to control or prevent exposure to hazardous biological agent(s). These should be
written and readily available to all workers working at Containment Level 2 or 3. A formal record of training must be
kept for all individuals working at Containment Level 3.
9.1 FORMAL TRAINING
All workers should attend the training course ‘Biological Agents Safety Awareness’ organized once a term.
9.2 LOCAL TRAINING & SUPERVISION
All workers must receive local training BEFORE starting work with hazardous biological agents on the key measures
required to prevent or control the risks associated with these hazardous agents (includes important working practices as
well as physical features of the containment facility).
Key elements of local training provided to workers include:






Hazardous nature of the biological hazard(s) associated with the work
How exposure could occur
Safe working practices to be applied (as described in this risk assessment e.g. safe storage, transport
and disposal of materials)
Spillage response within the safety cabinet / centrifuge
Spillage response elsewhere
Post exposure protocols
An appropriate level of supervision (based on knowledge and experience of workers) must also be applied to workers
before they are allowed to work independently.
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Confirm that local training will be provided to all workers. This must be
documented for all CL3 work and is recommended for all CL2 work.
10.
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EMERGENCY PROCEDURES
All questions must be answered and further details supplied when indicated.
NOTE that key working practices identified below must be documented in a Code of Practice (CoP) / Local Rules or
Standard Operating Procedure (SOP) for CL2 or higher work, or work covered by the Anti-Terrorism (Crime & Security) Act
10.1
Briefly describe the procedures in place for dealing with spillage of infectious or potentially infectious material.
Put N/R if not relevant.
Click here to enter text.
Within the safety cabinet
Within the centrifuge
Click here to enter text.
Within the laboratory but outside of any
Click here to enter text.
primary control measure e.g. safety cabinet
Outside of the laboratory e.g. during
Click here to enter text.
transportation of material between labs
10.2
Describe the procedures in place for an accidental exposure e.g. inoculation injury or eye splash
Immediate action
Click here to enter text.
When & to whom to report the accident
Click here to enter text.
11.
ACCESS / SECURITY
All questions in this section must be answered for all work at CL2 or higher, or work covered by the AntiTerrorism (Crime and Security) Act.
11.1
Is the lab(s) or other work areas shared with other
users not involved in this project
Choose an item.
If yes, explain who and what procedures are in place
to control any risk to them: Click here to enter text.
11.2
What is the containment level(s) of this room(s)?
Click here to enter text.
11.3
How is access to the lab(s) restricted e.g. signage,
swipe card
Click here to enter text.
11.4
Describe the measures in place to ensure secure
storage of infectious material
Click here to enter text.
12.
OCCUPATIONAL HEALTH / HEALTH SURVEILLANCE
This section to be completed for work with biological agents or GMMs in Hazard Group 2 or higher and for
work with unscreened human tissues ONLY
12.1
Does the work involve Hazard Group 3 biological
agents?
Choose an item.
12.2
Describe any necessary health surveillance
requirements (health surveillance is necessary if
organism a) produces an identifiable disease / adverse
health effect; b) there is reasonable likelihood that the
disease / effect might occur, & c) there are valid
techniques for detecting indications of the disease or
effect)
Click here to enter text.
12.3
Are vaccinations required? If so, which ones?
Click here to enter text.
12.4
Persons at special risk?
Click here to enter text.
Does the nature of this
If yes, a health assessment form will need to be completed
for all workers, before returning to the Occupational
Health Advisor
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work preclude it being undertaken by any workers
who have a serious skin condition (e.g. eczema) or
other health problems that might make them more
susceptible to infection (e.g. some kind of
immunological defect)?
13.
CONTAINMENT LEVEL
To be completed for all activities
Confirm the relevant (COSHH / GM / SAPO) Containment Level requirements for each aspect or
component of this project. If different aspects of this work require different Containment Levels, then all
must be listed.
Note 1: the Containment Level(s) selected represent the minimum containment measures required- other
measures, identified in this risk assessment (e.g. use of sealed centrifuge rotor buckets), must also be
applied if considered necessary to prevent loss of containment.
Note 2: in addition to the containment & control measures set out in the relevant containment tables, the
Principles of Good Microbiological Practice must also be applied.
13.1
GM microbial containment Levels (1-4) and associated control measures (GM Regs)
Further guidance on GM containment levels
Wild type microbial containment Levels (1-4) & associated control measures (COSHH Regs)
Further guidance on COSHH containment levels
Animal Pathogen containment Levels (1-4) & associated control measures (Specified Animal Pathogens Order)
Project aspect
Where will work be
carried out?
Containment Level
required under
COSHH or GMO
(Contained Use) Regs
Containment Level
required by SAPO
(animal pathogens)
With derogation
from certain controls
(list these, if relevant)
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Reduction in (Derogation from) Control Measures:
If applicable, justify why specific control measure(s) identified above, normally applied for the selected
containment level, is/are considered unnecessary:
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14.
GM CLASS
14.1
Confirm the class of all GMMs in use
This section must be completed for work with Genetically Modified Micro-organisms only
Consider the GM Class(es) (directly related to the required containment level(s) identified above) for all aspects of the
project. Some aspects of this project could be assigned to a lower class (e.g. if the project involves the use of several
GMMs some of which are less hazardous than others). The overall project classification will represent the containment
level required for the most hazardous GMM to be used.
Note 1: if work is assigned to activity class 1, the GMO must present no or negligible risk either to humans or to the
environment
Note 2: work assigned to activity classes 2 or above must be notified to the HSE (after approval by the University
Biological Agents Safety Committee) before work can begin. A notification fee will be payable.
Project aspect
GM Class
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Overall project GM Class
(based on highest GM Class required)
15.
CONFIDENTIALITY
15.1
All risk assessments are reviewed and approved by the University’s Biological Agents Safety Committee and
minutes of these meetings are made widely available to individuals within the University and also on the web.
Are there any aspects of this project that
you feel should be treated as confidential?
If yes, which ones?
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Choose an item.
16.
RISK ASSESSMENT REVIEW
16.1
HTTP://WWW.YORK.AC.UK/BIOLOGY/INTRANET/HEALTH-SAFETY/BIOLOGICAL-SAFETY/RISK-ASSESSMENTS2/BIOLOGICAL-RA-REVIEW/
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