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Supporting Informations
Supplemental Table 1
Baseline characteristics and results of included trials
Supplemental Table 1 Baseline characteristics and results of included trials
Author
Year Volatile agent Comparison
Amr YM
2010 Isoflurane
Ballester M
Bein B
Belhomme D
Bignami E
Cavalca V
Choi YS
2011
2005
1999
2011
2008
2011
Conzen PF
Cromheecke S
De Hert SG
2003 Sevoflurane
2006 Sevoflurane
2003 Sevoflurane,
desflurane
2004 Sevoflurane,
desflurane
2004 Sevoflurane
2009 Sevoflurane,
desflurane
2010 Isoflurane
2005 Sevoflurane
2012 Sevoflurane
2006 Desflurane
2012 Sevoflurane
1992 Desflurane
2010 Sevoflurane
De Hert SG
De Hert SG (b)
De Hert SG
Flier S
Garcia C
Godzik W
Guarracino F
Hellstrom J
Helman JD
Hong DM
Sevoflurane
Sevoflurane
Isoflurane
Sevoflurane
Sevoflurane
Sevoflurane
Volatile vs TIVA vs
remote-TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Dead and
Dead and
Dead and patients in
Sample patients in
patients in remotesize
volatile group TIVA group volatile group
Dead and
patients in
remote-TIVA Longest
group
follow-up
45
1/15
1/15
0/15 1 year
40
52
20
100
44
76
1/21
0/26
0/10
1/50
0/22
0/38
0/19
0/26
0/10
1/50
0/22
23
30
45
0/12
0/15
0/30
0/11
0/15
1/15
Hospital stay
Hospital stay
36 hours
Volatile vs TIVA
320
0/160
2/160
Hospital stay
Volatile vs TIVA
Volatile vs TIVA
200
414
0/150
13/269
0/50
18/145
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs remotevolatile
100
72
60
112
100
200
133
0/51
0/37
0/40
0/57
1/50
1/100
0/66
2/49
0/35
0/20
1/55
0/50
3/100
0/38
1 year
Hospital stay
3 days
1 year
24 hours
Hospital stay
30 days
1 year
0/67
1 year
1 year
1 day
30 days
30 days
3 days
Hospital stay
Hong DM
2012 -
Hong DM
2013 -
Howie MB
1996 Isoflurane
Huang Z
Jovic M
Kendall JB
Kim JC
2011
2012
2004
2012
Kottenberg E
2012 Isoflurane
Landoni G
Lee MC
Leung JM
Li L
2007
2006
1991
2010
Lomivorotov VV
2012 Isoflurane
Lucchinetti E
2012 Isoflurane
Meco M
Meybohm
2007 Desflurane
2013 -
Musialowicz T
Rahman IA
2007 Isoflurane
2010 Sevoflurane
Royse CF
Saxena P
2011 Desflurane
2013 NA
Isoflurane
Sevoflurane
Isoflurane
NA
Desflurane
Isoflurane
Isoflurane
Isoflurane
TIVA vs remoteTIVA
TIVA vs remoteTIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs TIVA vs
remote-volatile vs
remote-TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs remotevolatile
Volatile vs remotevolatile
Volatile vs TIVA
TIVA vs remoteTIVA
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs TIVA
Volatile vs remotevolatile
70
0/35
1328
14/663
50
0/27
0/23
90
22
20
54
0/30
0/11
0/10
0/27
0/60
0/11
0/10
72
0/19
0/19
120
40
186
81
0/59
1/20
1/62
0/27
2/61
1/20
3/124
80
0/35 30 days
10/665 Hospital stay
0/27
0/20
4 hours after
surgical intensive
care
Hospital stay
Hospital stay
48 hours
Hospital stay
0/14 72 hours
0/54
30 days
Hospital stay
3 days
30 days
0/40
0/40
48 hours
55
1/28
0/27
6 months
28
180
0/14
0/14
2/90
24
162
0/12
1/82
0/12
182
30
0/91
0/15
0/91
72 hours
4/90 3 months
0/80
End of surgery
30 days
0/15
1 year
Hospital stay
Schoen J
Soro S
Story DA
Tempe DK
Thielmann M
2011 Sevoflurane
2012 Sevoflurane
2001 Sevoflurane,
isoflurane
2011 Isoflurane
2010 Isoflurane
Thielmann M
2013 Isoflurane
Tritapepe L
Tritapepe L
Wagner R
2003 Desflurane
2007 Desflurane
2010 -
Williams JM
2012 Isoflurane
Wu Q
2011 -
Xie J
2012 Sevoflurane
Yildirim V
Young PJ
2009 Sevoflurane,
isoflurane
2012 Isoflurane
Ziemmerman
2011 Isoflurane
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs remotevolatile
Volatile vs TIVA
Volatile vs TIVA
TIVA vs remoteTIVA
Volatile vs remotevolatile
TIVA vs remoteTIVA
Volatile vs remotevolatile
Volatile vs TIVA
Volatile vs remotevolatile
Volatile vs remotevolatile
128
73
360
2/64
2/36
1/240
0/64
0/37
1/120
40
53
0/20
0/26
0/20
329
11/167
107
150
101
1/52
1/75
96
0/48
75
Hospital stay
Hospital stay
3 days
0/27
7 days
30 days
3/162
1 year
3/55
1/75
0/68
30 days
ICU stay
0/33 24 hours
0/48
0/25
12 hours
0/50 End of surgery
73
1/35
0/38
60
0/40
96
1/48
1/48
30 days
120
0/60
1/60
Hospital stay
0/20
3 month
30 days