Summary of Search Results & Strategy – GUIDELINES, Clinical Trials, RCTs, Systematic Reviews & Meta-Analyses – Environmental Allergy Date 11/8/14 11/15/14 11/8/14 Database PUBMED PUBMED PUBMED Search Strategy Hits Search "Dander"[Mesh] 6 Filters: published in the last 10 years ((("meta analysis"[Publication Type] OR "review"[Publication Type]))) AND Filters:published in the last 10 years 0 ((("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type]))) 2 AND (("guideline"[Publication Type] OR "practice guideline"[Publication Type])) 0 Search "Fungi"[Majr] AND ("Allergens"[Mesh] OR "Hypersensitivity"[Mesh] OR "Allergy and Immunology"[Mesh]) Filters: published in the last 10 years 86235 AND (("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type])) 37 AND (("meta analysis"[Publication Type] OR "review"[Publication Type])) 124 ((("guideline"[Publication Type] OR "practice guideline"[Publication Type]))) 0 1037 Search "Air Pollutants"[Mesh] Filters: published in the last 10 years AND (("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type])) 285 AND (("meta analysis"[Publication Type] OR "review"[Publication Type])) 1221 ((("guideline"[Publication Type] OR 9 Articles Selected 11/9/14 11/11/14 PUBMED PUBMED "practice guideline"[Publication Type]))) ""Volatile Organic Compounds"[Mesh] Filters: published in the last 10 years 3672 AND (("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type])) 38 (("meta analysis"[Publication Type] OR "review"[Publication Type])) 246 (("guideline"[Publication Type] OR "practice guideline"[Publication Type]) 1 "Rodentia"[Majr] 119 AND ("Allergens"[Mesh]) OR "Hypersensitivity"[Mesh] OR "Allergy and Immunology"[Mesh] Filters: published in the last 10 years ((("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type]))) (("meta analysis"[Publication Type] OR "review"[Publication Type])) ((("guideline"[Publication Type] OR "practice guideline"[Publication Type]))) 11/11/14 PUBMED ""Cockroaches"[Mesh] AND ("Allergens"[Mesh] OR "Hypersensitivity"[Mesh] OR "Allergy and Immunology"[Mesh]) 1 20 1 309 Filters: published in the last 10 years ((("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type]))) 27 (("meta analysis"[Publication Type] 32 OR "review"[Publication Type])) ((("guideline"[Publication Type] OR "practice guideline"[Publication Type]))) 11/11/14 PubMed 1 "Pollen"[Mesh] AND ("Allergens"[Mesh] OR "Hypersensitivity"[Mesh] OR "Allergy and Immunology"[Mesh] ) Filters: published in the last 10 years AND 11/15/14 11/18/14 National Guidelines Clearinghouse CMA Infobase ((("clinical trial"[Publication Type] OR "controlled clinical trial"[Publication Type] OR "randomized controlled trial"[Publication Type]))) 332 (("meta analysis"[Publication Type] OR "review"[Publication Type])) 169 ((("guideline"[Publication Type] OR "practice guideline"[Publication Type]))) 0 Search “cockroach” 0 Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen 0 0 0 0 1 1 0 Publication Year: 2004-2014 Keyword: (Include search in abstract) cockroach Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen 0 0 0 0 0 0 0 0 Date- 2004/01/01—2015/01/01 11/18/14 SIGN Scotland Manual search of guidelines cockroach 1 Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen 11/20/14 NICE Evidence Search 0 1 1 0 1 4 8 “cockroach” AND Type of Information “Guidance” 8 Type of Information “Systematic Review” 16 “fungus” AND “allergy Type of Information Guidance Drug Best Practice Guidance 55 Ongoing Trial 3 Systematic Review 34 “Mold AND allergy” Ongoing Trials 1 Systematic Review 13 Guidance 20 “Rodent AND allergy” Systematic Review 11 Guidance 27 “Volatile Organic Compound” Systematic Review 14 Guidance 17 Ongoing Trials 1 “Dander” Systematic Review 18 Guidance 16 “Pollen AND allergy” Systematic Review 75 11/22/14 New Zealand Guidelines Group Guidance 35 Drug Best Practice Guidance 2 Ongoing Trial 5 Manual search of guidelines cockroach Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen 11/22/14 11/22/14 11/22/14 Australian National Health and Medical Research Council Guidelines Search Guidelines International Network Search TRIP Database All searches from:2004 to:2015 cockroach Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen cockroach Fungus Fungi Mold Rodent Volatile Organic Compound Dander Pollen 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 “cockroach” Evidence type “Systematic Reviews” 4 Guidelines 32 Controlled Trials 77 (Fungus and Allergy) Evidence type “Systematic Reviews” 16 Guidelines 168 Controlled Trials 104 (Mold and Allergy) Evidence type “Systematic Reviews” 3 Guidelines 83 Controlled Trials 30 (Rodent and Allergy) Evidence type “Systematic Reviews” 13 Guidelines 40 Controlled Trials 26 (Volatile Organic Compound AND Allergy) 1 Evidence type “Systematic Reviews” 18 Guidelines 8 Controlled Trials (Dander AND Allergy) Evidence type “Systematic Reviews” 6 Guidelines 32 Controlled Trials 21 (Pollen AND Allergy) Evidence type “Systematic Reviews” 28 Guidelines 74 Controlled Trials 514 11/22/14 HSTAT “cockroach and allergy” “Fungus and allergy” “Mold and allergy” “Rodent and allergy” “Volatile Organic Compound“ “Dander and allergy” “Pollen and allergy” 11/22/14 Clinicaltrials.gov insect | received from 01/01/2004 to 10/5/2014 | updated from 01/01/2004 to 10/5/2014 “cockroach” “Fungus and allergy” “Mold and allergy” “Rodent and allergy” “Volatile Organic Compound and allergy“ “Dander and allergy” “Pollen and allergy” 11/23/14 EMBASE 'cockroach'/exp AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py 3 selected 3 2 0 0 1 0 19 studies 50 studies 11 studies 0 studies 3 studies 14 studies 289 studies 1169 ('clinical trial'/de OR 'randomized controlled trial'/de OR 'controlled clinical trial'/de) 30 'practice guideline'/de 27 ('meta analysis'/de OR 'systematic review'/de) 7 'fungus'/exp AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py 8128 ('clinical trial'/de OR 'randomized controlled trial'/de OR 'controlled clinical trial'/de) 397 'practice guideline'/de 102 ('meta analysis'/de OR 'systematic review'/de) 75 'rodent'/mj AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py AND 'clinical trial'/de 2 11/23/14 CINAHL 'volatile organic compound'/exp AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py 321 AND 'clinical trial'/de 9 AND 'systematic review'/de 4 'dander'/exp AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py 663 ('clinical trial'/de OR 'controlled clinical trial'/de OR 'randomized controlled trial'/de) 35 AND 'practice guideline'/de 15 AND 'systematic review'/de 8 'pollen'/exp AND ('immunology'/exp OR 'hypersensitivity'/exp OR 'allergen'/exp OR 'allergy'/exp) AND [2004-2014]/py 5609 AND 'practice guideline'/de 52 AND 'systematic review'/de 55 ('clinical trial'/de OR 'controlled clinical trial'/de OR 'randomized controlled trial'/de) 437 “cockroach” “Fungus and allergy” “Mold and allergy” “Rodent and allergy” “Volatile Organic Compound and allergy“ “Dander and allergy” “Pollen and allergy” (MH "Cockroaches") AND ( (MH "Allergens+") OR (MH "Hypersensitivity+") ) Published Date: 20040101-20141231 78 AND PT clinical trial 2 AND PT systematic review 0 AND PT practice guidelines 0 11/23/2014 CINAHL ( (MH "Fungi+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT clinical trial 3 ( (MH "Fungi+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT systematic review 7 ( (MH "Fungi+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT practice guidelines 1 ( (MH "Rodents+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT clinical trial 8 ( (MH "Rodents+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT systematic review 5 ( (MH "Rodents+") AND ((MH "Allergens+") OR (MH "Hypersensitivity+")) ) AND PT practice guidelines 2 “Volatile organic compound” (keyword) AND PT practice guidelines AND PT systematic review AND PT clinical trial 15 0 0 0 “dander” (keyword) AND PT clinical trial AND PT systematic review AND PT practice guidelines 42 0 1 0 (MH "Pollen") 467 AND PT clinical trial AND PT systematic review AND PT practice guidelines 33 5 0