Running head: PICOT PROPOSAL 1 PICOT Proposal Katherine Jackson University of South Florida PICOT PROPOSAL 2 University of South Florida College of Nursing NUR 4169C EBP for the Baccalaureate RN PICOT Proposal Form Briefly describe the opportunity for clinical improvement. Briefly describe the background of the problem. Why is this issue important for your clinical setting or organization? List 1-2 background pertinent questions. State the PICOT question. Describe the ideas you have for solving the problem. Type Information/Response in this Column There is an opportunity to lessen the amount of time pediatric patients undergoing cardiac catheterizations spend in states of hypoxia. The use of Near Infrared Spectroscopy for prompt detection of impaired tissue perfusion may be used. Prompt identification of impaired oxygenation can help shorten the time patients spend in a hypoxia, essentially reducing complications of impaired perfusion. Cardiac catheterization is recommended for diagnostic purposes in pediatric patients with congenital heart defects, predominantly when noninvasive interventions are unsuccessful in diagnosing CHD. Inadequate tissue oxygenation is often a pre-existing condition for patients in this population, constructing impaired tissue oxygenation a strong possibility during the perioperative period. Cerebral hypoxia complications are among the most common complications encountered in pediatric patients undergoing cardiac catheterization. Traditionally, pulse oximetry allows for a simple, noninvasive estimation of arterial oxygen saturation; pulse oximetry has been the gold standard utilized in pediatric intensive and perioperative care. More recently, NIRS has been used to monitor tissue oxygenation in cerebral and organ tissue of pediatric patients. NIRS measures the spectral differences in tissue caused by the presence of oxygenated hemoglobin and deoxygenated hemoglobin. Perhaps NIRS can be proven more prompt in detecting impaired oxygenation compared to pulse oximetry. Timeliness in addition to the accuracy of NIRS, will provide a solid argument NIRS should be utilized as the new gold standard on pediatric patients undergoing cardiac catheterizations and other high-risk procedures. What is impaired tissue perfusion? What are complications of impaired tissue perfusion? Specifically, why are pediatric patients undergoing cardiac catheterization at risk for impaired tissue perfusion? What is the difference in mechanism of NIRS compared to pulse oximetry? In pediatric patients undergoing cardiac catheterization, is NIRS compared with pulse oximetry more prompt in diagnosing impaired tissue perfusion during the intraoperative and postoperative period? Data will be collected from NIRS simultaneously with data collected from pulse oximetry; the patient will have a pulse oximeter probe attached to the finger and NIRS probes attached to the head. Data collected from each method will be compared to observe at what point in time impaired tissue perfusion is detected, in other words, which method detects impaired perfusion sooner. PICOT PROPOSAL Describe your proposed goals/objectives for the project. What do you hope to achieve? How will you measure/evaluate the outcome of your change/improvement? Describe the members of your proposed project team (by position or job title) and their roles. Institution where the project might be implemented in the future. List 3 peer reviewed research papers that will provide the evidence for the PICOT on the reference page. 3 Post-procedural care will be performed in the usual manner. The data collected will be the amount of time the patients spend within the normal range of tissue oxygenation (SctO2 70%-80% with the NIRS and SaO2 94%-100% with pulse oximeter), and the actual O2 readings for each method will be recorded. A difference in time between the initial NIRS alert versus the initial pulse oximeter alert of impaired tissue oxygenation will show which method is more time efficient in detecting impaired tissue perfusion in pediatric patients. I would like to show the reliability of NIRS in identifying impaired tissue perfusion in a narrower time range compared to pulse oximetry. The benefit of NIRS in detecting compromised perfusion sooner than the gold standard of pulse oximetry, will produce the outcome of earlier interventions and ultimately shorter periods of hypoxia in pediatric patients. A pulse oximeter probe will be placed on the patient’s finger and NIRS probes will be placed on the patient’s head during the catheterization period. The nurse will record measurements of oxygen levels (SaO2 and SctO2) on a data collection tool, including the time of each measurement and the time of detected oxygenation impairments-if any-for NIRS and the pulse oximetry probe. Comparing the data will illustrate which method detects compromised tissue perfusion earlier. Cardiac CRNA-The Certified Registered Nurse Anesthetist(s) implements/monitors the use of NIRS and pulse oximetry during cardiac catheterizations in pediatric patients. CVICU RN-The staff nurse(s) continue monitoring NIRS and pulse oximetry during the post-cardiac catheterization period in pediatric patients. Clinical Research Coordinator, RN-Coordinates research in pediatric cardiology; a wonderful source of information, including how to interpret and organize data. Helps get authorization from the IRB to undergo research. Any facility that offers pediatric cardiac catheterizations. The catheterization labs/OR, PACU, and CVICU. See reference page. PICOT PROPOSAL 4 References Cristia, A., Dupoux, E., Hakuno, Y., Lloyd-Fox, S., Schuetze, M., Kivitis, J., Bergvelt, T., Gelder, V.M., Fillipin. L., Charron, S., & Minagawa-Kawai, Y. (2013). An online database of infant functional near infraRed spectroscopy studies: a communityaugmented systematic review. PLOS|one, 8(3), 1-10. Doi:10.1371/journal.pone.0058906 Feltes, T.F., Bacha, E., Beekman, R.H.; Cheatham, J.P., Feinstein, J.A.; Gomes, A.S., Hijazi, G.G., Ing, F.F., Moore, M., Morrow, R.W., Mullins, C.E., Taubert, K., & Zhaun, E. (2011). Indications for cardiac catheterization and intervention in pediatric cardiac disease: a scientific statement from the American Heart Association. American Heart Association, 123(22), 2607-2652. Doi: 10.1161/CIR.0b013e31821b1f10 Fouzas, S., Priftis, K., & Anthracopoulos, M.B. (2011). Pulse oximetry in pediatric practice. The American Academy of Pediatrics, 128(4), 740-752. Doi: 10.1542/peds.2011-0271 Frost, E. (2012, April). Cerebral oximetry: Emerging applications for an established technology. Anesthesiology News, 1-7. Retrieved from http://www.anesthesiologynews.com/ViewArticle.aspx?t=Blogs&d=Special+Edition+%2 F+Educational+Reviews&d_id=161&i=October+2012&i_id=890&a_id=21822 Hansen, J.H., Schlangen, J., Armbrust, S., Jung, O., Scheewe, J., & Kramer, H.H. (2013). Monitoring of regional tissue oxygenation with near-infrared spectroscopy during the early postoperative course after superior cavopulmonary anastomosis. European Journal of Cardio-Thoracic Surgery, 43(2), 37-43. Doi: 10.1093/ejcts/ezs581 PICOT PROPOSAL 5 Hirsch, J., Charpie, J., Gurney, J., & Ohye, R. (2010). Role of near infrared spectroscopy in pediatric cardiac surgery. Progress in Pediatric Cardiology, 29(2), 93-96. Doi:10.1016/j.ppedcard.2010.06.003 Schachner, T., Bonaros, N., Bonatti, J., & Kolbitsch, C. (2008). Near infrared spectroscopy for controlling the quality of distal leg perfusion in remote access cardiopulmonary bypass. European Journal of Cardiothoracic Surgery, 34(6), 1253-1254. Doi: 10.1016/j.ejcts.2008.08.027 Tobias, J.D., & Hoerneschemeyer, D.G. (2007). Near infrared spectroscopy identifies compartment syndrome in infant. Journal of Pediatric Orthopaedics, 27(3), 311-313. Doi: 10.1097/BPO.0b013e3180326591 Yu,G., Shang,Y., Zhao, Y., Cheng, R., Dong, L., & Saha, S.P. (2011). Intraoperative evaluation of the revascularization effect on ischemic muscle hemodynamics using near infrared diffuse optical spectroscopies. Journal of Biomed Optical Spectroscopy, 16(2), 270-274. Doi: 10.1117/1.3533320