Pubblicazioni
ARIANNA MONTANARI, YOU FANG ZHOU, MONIQUE BOLOTIN-FUKUHARA, LAURA FRONTALI AND SILVIA
FRANCISCI (2013) Analysing the suppression of respiratory defects in the yeast model of human
mitochondrial tRNA diseases. Gene. May 30. doi:pii: S0378-1119(13)00678-110.1016/j.gene.2013.05.042.
MARIO D CORDERO, JUAN GARRIDO-MARAVER, IRENE DOMÍNGUEZ MOÑINO,DAVID COTÁN, MARIO DE LA
MATA, MANUEL OROPESA-AVILA, MANUEL DE MIGUEL, JUAN BAUTISTA LORITE, ELOYRIVAS INFANTE,
MANUEL ÁLVAREZ DOLADO, PLÁCIDO NAVAS, SANDRA JACKSON, SILVIA FRANCISCI JOSÉ A SÁNCHEZ
ALCÁZAR (2012) Screening of effective pharmacological treatments for MELAS syndrome using yeasts,
fibroblasts and cybrids models of the disease Br J Pharmacol. 167(6):1311-1328
ELENA PERLI, CARLA GIORDANO, HELEN A.L. TUPPEN, MONICA MONTOPOLI, ARIANNA MONTANARI,
MAURIZIA ORLANDI, ANNALINDA PISANO, DANIELA CATANZARO, LAURA CAPARROTTA, BARBARA
MUSUMECI, CAMILLO AUTORE, VERONICA MOREA, PATRIZIO DI MICCO, ANTONIO CAMPESE, MARTINA
LEOPIZZI, PIETRO GALLO, SILVIA FRANCISCI, LAURA FRONTALI, ROBERT W. TAYLOR, GIULIA D’AMATI (2012)
Isoleucyl-tRNAsynthetase levels modulate the penetrance of a homoplasmic m.4277T>C mitochondrial
tRNAIle mutation causing hypertrophic cardiomyopathy. Hum. Mol.Genet. Hum Mol Genet., 21,85-100.
SILVIA FRANCISCI, ARIANNA MONTANARI, CRISTINA DE LUCA,LAURA FRONTALI (2011) Peptides from
aminoacyl-tRNAsynthetases can cure the defects due to mutations in mt tRNAgenes Mitochondrion 11,
919–923
ARIANNA MONTANARI,CRISTINA DE LUCA, LAURA FRONTALI, and SILVIA FRANCISCI (2010) AminoacyltRNAsynthetases are multivalent suppressors of defects due to human equivalent mutations in yeast
mttRNA genes. Biochimica et Biophysica Acta 1803 , 1050–1057
DE LUCA C, ZHOU Y, MONTANARI A, MOREA V, OLIVA R, BESAGNI C, BOLOTIN-FUKUHARA M, FRANCISCI S.
(2009). Can Yeast be used to study mitochondrial diseases? Biolistic mutants for the analysis of mechanisms
and suppressors .Mitochondrion, vol 9; p. 408–417,
MONTANARI A, BESAGNI C, DE LUCA C, MOREA V, OLIVA R, TRAMONTANO A, BOLOTIN-FUKUHARA M,
FRONTALI L, FRANCISCI S. (2008). Yeast as a model of human mitochondrial tRNA base substitutions:
Investigation of the molecular basis of respiratory defects.RNA, vol. 14; p. 275–283. ISSN: 1355-8382
C. DE LUCA, C. BESAGNI, L. FRONTALI, M. BOLOTIN-FUKUHARA, FRANCISCI S. (2006). Mutations in yeast
mttRNAs: specific and general suppression by nuclear encoded tRNAinteractors. GENE, vol. 377; p. 169-176,
ISSN: 0378-1119
BESAGNI, C. DE LUCA, FRANCISCI S., L. FRONTALI, M. BOLOTIN FUKUHARA (2005). The effects of some
human pathogenic mutations in mitochondrial tRNA genes can be studied and suppressed in yeast. YEAST,
vol. 22; p. 166, ISSN: 0749-503X
FRANCISCI S., DE LUCA C., OLIVA R, MOREA V., TRAMONTANO A. AND FRONTALI L. (2005). Aminoacylation
and conformational properties of yeast mitochondrial tRNA mutants with respiratory deficiency.RNA, vol.
11; p. 914-927, ISSN: 1355-8382
L.FRONTALI, FRANCISCI S., C. DE LUCA, V. MOREA, R. OLIVA AND A. TRAMONTANO (2005). Yeast as a tool
for in vivo study of human mitochondrial tRNA mutations: a study of nuclear suppressors in yeast. YEAST,
vol. 22; p. 159, ISSN: 0749-503X
Feuermann M., Francisci S., Rinaldi T., De Luca C., Rohou H., Frontali L. and Bolotin-Fukuhara M. (2003) The
Yeast counterparts of human ‘MELAS’ mutations cause mitochondrial dysfunction which can be rescued by
overexpression of the mitochondrial translation factor EF-Tu EMBO Reports 4, 53-58
RINALDI T, GAMBADORO A., FRANCISCI S., FRONTALI L. (2003). Nuclear-mitocondrial interactions in
Saccharomyces cerevisiae: characterization of a nuclear suppressor of a defect in mitochondrial tRNAasp
processing. GENE, vol. 303; p. 63-68, ISSN: 0378-1119
FIORI A, FRANCISCI S., FALCONE C (2002). Suppression of a nuclear frameshift mutation by a mitochondrial
tRNA in the yeast Kluyveromyceslactis. MOLECULAR MICROBIOLOGY, vol. 46; p. 169-177, ISSN: 0950-382X
ROHOU H, FRANCISCI S., RINALDI T, FRONTALI L, BOLOTIN FUKUHARA M (2001). Reintroduction of a
characterized mittRNAgly mutation into yeast mitochondria provides a new tool for the study of human
neurodegenerative diseases. YEAST, vol. 18; p. 219-227, ISSN: 0749-503X
FIORI A, BIANCHI M.M, FABIANI L, FALCONE C, FRANCISCI S., PALLESCHI C, SOLIMANDO N, D. UCCELLETTI,
FRONTALI L (2000). Disruption of six novel genes from chromosome VII of Saccharomyces cerevisiae reveals
one essentia gene and one gene which affects the growth rate. YEAST, vol. 16; p. 377-386, ISSN: 0749-503X
FRANCISCI S., BOHN C., FRONTALI L., BOLOTIN FUKUHARA M. (1998). Ts mutations in mitochondrial tRNA
genes: characterization and effect of two point mutations in the mitochondrial gene for tRNAphe in
Saccharomyces cerevisiae. CURRENT GENETICS, vol. 33; p. 110-116, ISSN: 0172-8083
T.RINALDI, FRANCISCI S., E. ZENNARO, L. FRONTALI, M. BOLOTIN FUKUHARA (1994). Suppression of a
mitochondrial point mutation in a tRNA gene can cast light on the mechanisms of 3’end processing.
CURRENT GENETICS, vol. 25; p. 451-456, ISSN: 0172-8083
P. GRISANTI, FRANCISCI S., P. TATASEO, C. PALLESCHI (1993). Symmetrical transcription in the tRNA region
of the mitochondrial genome of S.cerevisie. CURRENT GENETICS, vol. 24; p. 122-127, ISSN: 0172-8083
E. ZENNARO, FRANCISCI S., A. RAGNINI, L. FRONTALI, M. BOLOTIN FUKUHARA (1989). A point mutation in a
mitochondrial tRNA, abolishes its 3’end processing. NUCLEIC ACIDS RESEARCH, vol. 17; p. 5751-5756, ISSN:
0305-1048
FRANCISCI S., C. PALLESCHI, A. RAGNINI, L. FRONTALI (1987). Analysis of transcripts of the major cluster of
tRNA genes in the mitochondrial genome of S.cerevisiae. NUCLEIC ACIDS RESEARCH, vol. 15; p. 6387-6391,
ISSN: 0305-1048
PALLESCHI, FRANCISCI S., E. ZENNARO, L. FRONTALI (1984). EXPRESSION OF THE CLUSTERED
MITOCHONDRIAL TRNAGENES IN S.. CEREVISIAE: TRANSCRIPTION AND PRO-CESSING OF TRANSCRIPTS.
EMBO JOURNAL, vol. 3; p. 1389-1393, ISSN: 0261-4189
PALLESCHI, FRANCISCI S., M. BIANCHI, L. FRONTALI (1984). Initiation of tran-scription of MitochondrialtRNA
gene cluster in S.cerevisiae. NUCLEIC ACIDS RESEARCH, vol. 12; p. 7317-7322, ISSN: 0305-1048
E. BOKER-SCHMITT, FRANCISCI S., R.J. SCHWEYEN (1982). Mutations releasing mitochondrial biogenesis
from glucose repression in S. cerevisiae. JOURNAL OF BACTERIOLOGY, vol. 151; p. 303-308, ISSN: 0021-9193
L. FRONTALI, C. PALLESCHI, FRANCISCI S. (1982). Transcripts of Mitochondrial tRNA genes in S.cerevisiae.
NUCLEIC ACIDS RESEARCH, vol. 10,; p. 7283-7288, ISSN: 0305-1048
G. BALDACCI, C. FALCONE, FRANCISCI S., C. PALLESCHI (1979). Mitochondrial protein synthesizing
machinery in S.cerevisiae. EUROPEAN JOURNAL OF BIOCHEMISTRY, vol. 98; p. 1811-1819, ISSN: 0014-2956
G. BALDACCI, E. CUNDARI, FRANCISCI S., C. PALLESCHI (1978). Variability of Mitochondrial alanyltRNAisoaccepting species in S. cerevisiae.BULLETIN OF MOLECULAR BIOLOGY AND MEDICINE, vol. 3; p. 343347, ISSN: 0391-481X