Table 1. Characteristics of the adult NHANES III genetic participants (n=5,955)
by CKD status.
Characteristics
Total
(n=5955)
42 (range 18,90)
CKD
(n=1175)
67 (48,77)
No CKD
(n=4780)
38 (28,48)
<0.0001
43% (n=2,652)
40%(521)
43.7% (2120)
0.01
Non-Hispanic White
39% (n=2400)
27%
73%
Non-Hispanic Black
28% (n=1712)
18%
82%
Mexican American
Others
28% (n=1745)
5% (n=287)
16%
20%
84%
80%
1 (0.9, 1.2)
1.07 (0.8-1.25)
0.88
<0.0001
93 (78, 109)
66 (53,87)
88 (77,104)
<0.0001
5.38 (2.66, 11.79)
35 (17, 87)
4 (21,74)
<0.0001
Age, median (IQR) years
Gender (males: %,n)
p-value
Race/Ethnicity (%,n)
0.02
Serum Creatinine, mg/dL,
median (IQR)
Median eGFR ml/min/1.73 m2 (IQR)
Urine albumin to creatinine ratio (IQR)
Albuminuria (n=6091)
<0.0001
None
Microalbuminuria
84% (n=5125)
14% (n=826)
25%
65%
100%
0%
Macroalbuminuria
2% (n=140)
10%
0%
119
(108, 134)
62 (64, 80)
136
(120, 155)
74 (66, 83)
117
(108, 129)
72 (65,79)
<0.0001
Hypertension, % (n)
22% (n=1324)
46% (n=593)
15% (n=731)
<0.0001
BMI, median (IQR)
26.5 (23, 30)
27 (24, 31)
26 (23, 30)
0.02
Systolic BP median (IQR), mmHg
Diastolic BP median (IQR), mmHg
C-reactive protein level (%)
0.07
<0.0001
<0.22 mg/dl
62% (n=3833)
53%
65%
0.22–0.99 mg/dl
29% (n= 1763)
34%
27%
9% (n=555)
13%
7%
17% (n=283)
21% (n=903)
0.002
<0.0001
>1.00 mg/dl
Current Smoking
20% (n=1186)
Prevalent CHD, %
7% (n=453)
19% (n=247)
4% (n=200)
Mean LDL, mg/dL
122 (99, 146)
120 (98, 144)
Diabetes (%)
10% (n=632)
133
(106, 157)
24% (n=310)
7% (n=318)
0.13
<0.0001
CKD: either low GFR or albuminuria
CKD stage III (eGFR 30-59 ml/min)
32.68% (n=384)
CKD stage IV (eGFR 15-29 ml/min)
1.36% (n=16)
CKD stage V (eGFR<15 ml/min)
0.5% (n=6)
*Categorical variables were tested using the Cochran-Mantel-Haenszel Test and continuous variables
were
tested using the Taylor Linearization method with SUDAAN. All tests were weighed.
§ CKD defined as either by decrease glomerular filtration rate (eGFR) or by the presence of
albuminuria