University of Toronto Lesson Plan: Grade 11 Biology, Genetic Processes Curriculum Instruction and Assessment Keith Ho Diana Colucci Tiffany Luk Candidate Names: Diana Colucci, Tiffany Luk, Keith Ho Unit and Title of Lesson: Unit D: Genetic Processes Lesson: Introduction to Mendelian Genetics and Monohybrid Crosses Curriculum Connections 1. Big Ideas: Genetic Processes Genetic and genomic research can have social and environmental implications. Variability and diversity of living organisms result from the distribution of genetic materials during the process of meiosis. 2. Ministry Expectations: (The Ontario Curriculum Grades 11 and 12: Science 2008) Overall Expectations D2. investigate genetic processes, including those that occur during meiosis, and analyze data to solve basic genetics problems involving monohybrid crosses Specific Expectations D2. Developing Skills of Investigation and Communication D2.1 use appropriate terminology related to genetic processes, including, but not limited to: heterozygous, homozygous, allele [C] D2.3 use the Punnett square method to solve basic genetics problems involving monohybrid crosses [PR, AI, C] D2.4 investigate, through laboratory inquiry or computer simulation, monohybrid crosses and use the Punnett square method and probability rules to analyse the qualitative and quantitative data and determine the parent genotype [PR, AI, C] D3. Understanding Basic Concepts D3.3 explain the concepts of genotype, phenotype, dominance and recessiveness according to Mendelian laws of inheritance From A. Scientific Investigation Skills and Career Exploration Analyzing and Interpreting [Al]* A1.8 synthesize, analyse, interpret, and evaluate qualitative and/or quantitative data to determine whether the evidence supports or refutes the initial prediction or hypothesis and whether it is consistent with scientific theory A1.10 draw conclusions based on inquiry results and research findings, and justify their conclusions with reference to scientific knowledge Communication [C]* Materials power point smart board chalkboard and chalk a group set of terms and definitions (Minds On – see Appendix A1 & A2) Class set of Worksheets A1.12 use appropriate numeric, symbolic, and graphic modes of representation (e.g., biological diagrams, Punnett squares), and appropriate units of measurement (e.g., SI and imperial units) 3. Student Learning Goals: By the end of this lesson, students will be able to: understand the Mendel’s genetic principles (principle of dominance, law of segregation, law of independent assortment) understand the difference between dominant and recessive genes understand how genotype influences phenotype use the Punnett square method and probability rules to complete monohybrid crosses 4. Prior Knowledge It is assumed that students have prior experience working together in groups to learn concepts through collaborative learning strategies. Some students may have an idea of inheritance from pop culture. From Grade 10 Science, Academic (SNC2D): B2. investigate cell division, cell specialization, organs, and systems in animals and plants, using research and inquiry skills, including various laboratory techniques Relevant expectations from the Gr. 11 Genetic Processes which predates this lesson: D2. Developing Skills of Investigation and Communication D2.2 investigate the process of meiosis, using a microscope or similar instrument, or a computer simulation, and draw biological diagrams to help explain the main phases in the process [PR, AI, C] D3. Understanding Basic Concepts D3.1 explain the phases in the process of meiosis in terms of cell division, the movement of chromosomes, and crossing over of genetic material; understand the basic terms and concepts related to heredity (chromosomes, genes, alleles, dominant, recessive) from the previous lesson: Introduction to Genetics Essential Question What are the benefits and social implications of knowing the genetic inheritance of living things? A. Minds On Review of Terms Activity (10 Minutes) T/L Strategies and Teacher Notes Rationale T/L Strategies Small Group Activity Individual Worksheet Review The terms are from the previous lesson and provide an opportunity for students to review. Allows students to practice the vocabulary and to consolidate the definitions of each term. Discussing the terms in small groups allows students to learn and understand the terms, and teach each other. Reviewing the answers as a class allows students an opportunity to consolidate the information and ask questions. students become aware of the traits they have, others have, and the variety of traits (population diversity) in the small population of the classroom Application of genetic terms, i.e. dominant and recessive engaging because all students are involved Matching activity Discuss: genes, traits, alleles. Review: heredity, dominance, recessive, heterozygote, homozygote. Introduce Mendel and pea pod traits T/L Strategies B. Action 1 Genetic Bingo Interactive Class activity Statistical Analysis and Class Statistics Guiding question (15 Minutes) Q: What accounts for the variability of our physical appearance? A: Some of the differences of our physical appearance are affected by dominant and recessive traits passed on by our biological parents. Bingo worksheet Students circle the traits they have Clarify for class to ensure they understand all Assessment (for Learning, of Learning, as Learning) Assessment of Learning The activity is self- or peer-guided discovery. The formative assessment would be for and as learning. Students will correct the answers themselves or with a partner. Assessment for learning Collecting the class statistics gives the instructor an idea of how many students have prior knowledge to the topic of dominant and recessive genes Students complete the worksheet and participate in the class statistics collection Ready-to-use support materials A1. Minds On Activity Instructions A2. Minds On Activity Sheet A3. Minds On Matching Worksheet A4. Minds On Matching Worksheet (Answer Key) B1. Bingo Worksheet B2. Bingo Worksheet (Answer Key) B3. Bingo Worksheet Parent 1 B4. Bingo Worksheet Parent 2 B5. Additional Teacher Notes/ Instructions C. Action 2 Lesson: Introduction to Punnet Squares (15 Minutes) traits listed on the worksheet The objective is for students to get up and move around the class to find peers who have traits they don’t have and get their peer to initial/sign in the box Collect Class Statistics Once activity completed, record class statistics on board/smart board i.e. how many individuals checked off box ‘a’? stand up or put your hand up, record numbers note: do not mention dominant and recessive yet Follow-up Home fun activity complete same worksheet regarding Parents’ traits (B3 & B4) T/L Strategies Lecture Questioning Mini class discussion Note taking Guiding questions Q: How can we determine the probability of inheritance of traits of the offspring given the parental genotype? A: We can determine the probability of inheritance of the offspring by using the Punnet Square method to perform a monohybrid cross. Q: How can we determine the likelihood that a person will inherit a disease from their parents? A: We can determine the likelihood if we know whether the gene for the disease is dominant or recessive and the parental genotypes (homozygous or heterozygous). Addressing the entire class together is the most timeefficient way to teach the material. Discussing new terms and reviewing past terms allows students to understand how they integrate into Punnet Squares. Completing and demonstrating monohybrid crosses allows students to see what is occurring before trying it themselves. Assessment for learning Teaching a lesson through questioning allows the instructor to assess students’ learning immediately to see if they are ready to move on to the next step B6. Fun with Punnet Squares Lesson D. Action 3 Fun with Punnet Squares Worksheet (20 Minutes) Introduction to Punnett Squares Lesson (use B.6 either on Computer-Projector, Overhead Projector, or Chalk board Notes as visual – can also give as a handout and go through/discuss) Remind students of alleles as genes on chromosomes (refer to traits in bingo activity) Transition: we need a way to predict inheritance of a phenotypic trait based the genotype (genes) of an individual Define “Punnet Square” What is a Punnet Square used for? How are Punnet Squares used? Demonstrate example monohybrid cross. T/L Strategies Seat work Problem solving Seat work on monohybrid crosses (Fun with Punnet Squares Worksheet – B7) Ask students to work independently or with a partner in their table groups to solve the 8 monohybrid crosses on the handout by following the instructions and referring to the lesson example visual (on board/projector/handout) Instructor will walk around the classroom to assess students’ learning and ask students to put answers on the black board/smart board/overhead Instructor will take up specific questions with the class if necessary T/L Strategies E. Small group activity Consolidation Peer Collaboration Small Group Problem solving Challenge Allow students to practice monohybrid crosses and to collaborate with their peers to consolidate concepts Allows the instructor to provide assistance to individual students and to clear students of their misconceptions. Assessment of Learning and Assessment for Learning The activity is self- or peer-guided discovery. Students will correct the answers themselves or with a partner. This activity can be used as a “ticket out the door” to add some motivation for students to complete the worksheets. B7. Fun with Punnet Squares Worksheet B8. Fun with Punnet Squares Worksheet (Answer Key) Allows students to collaborate and clear up misconceptions of their peers Allows teacher to assess students’ learning Assessment of Learning Teacher can assess students’ learning while they are C1. Small Group Challenge Activity C2. Small Group Challenge Activity (Answer Key) Activity (15 minutes) F. Next Steps Collect Work Exit Tickets Homework Small Group Challenge Question Activity Each table group (total 5 groups – 5 different questions) will work on a more challenging monohybrid cross problem given by the instructor Groups will hand in their answers to the teacher as an exit ticket out of class T/L Strategies Homework Wrap-up: Provide students an opportunity to ask questions regarding the material presented thus far. Preview material that is planned for the next lesson. Collect: B7. Fun with Punnet Squares Worksheet Collect: C1. Small Group Challenge Activity Distribute homework sheet: H1. Genetic Problems relating to Human Conditions Remind students of homework from Action 1: B3 & B4: Bingo Work sheet for Parent 1 and Parent 2 working on the questions in class and from their written answers to be marked Allows students an opportunity to clarify the material presented. Allows the instructor to prepare for further lessons. Previewing future material allows students who are interested to complete some personal research. Homework to further consolidate the material and challenge students. An opportunity to gage how comfortable the class is with the material; an Assessment for Learning. H1. Genetic Problems relating to Human Conditions H2. Genetic Problems Relating to Human Conditions (Answer Key) Appendix A. Minds On Review of Terms Activity A1. Minds On Activity Instructions A2. Minds On Activity Sheet A3. Minds On Matching Worksheet A4. Minds On Matching Worksheet (Answer Key) B. Action 1 Genetic Bingo and Class Statistics B1. Bingo Worksheet B2. Bingo Worksheet (Answer Key) B3. Bingo Worksheet Parent 1 B4. Bingo Worksheet Parent 2 B5. Additional Teacher Notes/ Instructions C. Action 2 Lesson: Introduction to Punnett Squares B6. Fun with Punnet Squares Lesson D. Action 3 Fun with Punnett Squares Worksheet B7. Fun with Punnet Squares Worksheet B8. Fun with Punnet Squares Worksheet (Answer Key) E. Consolidation C1. Small Group Challenge Activity C2. Small Group Challenge Activity (Answer Key) F. Next Steps H1. Genetic Problems relating to Human Conditions H2. Genetic Problems Relating to Human Conditions (Answer Key)