Supplemental Table 6. Differentially Expressed Genes in Granulocytes in JIA Patients Who Achieved
Remission with Methotrexate and Etanercept vs Methotrexate alone
Gene
Symbol
ABTB1
ANGPT1
ARHGEF3
BIRC3
BTNL8
CCNG1
CLIC4
CX3CR1
CYBB
[DDIT3 ///
NR1H3]
DDX3Y
DNAJC10
EIF1AY
EIF1AY
EIF1AY
ESD
HDHD1A
HIST1H1C
HIST1H2B
F
HLA-DOB
IGF1R
IL6ST
KIAA1683
MYCL1
Gene Title
ankyrin repeat and BTB (POZ) domain
containing 1
angiopoietin 1
Rho guanine nucleotide exchange
factor (GEF) 3
baculoviral IAP repeat-containing 3
butyrophilin-like 8
cyclin G1
chloride intracellular channel 4
chemokine (C-X3-C motif) receptor 1
cytochrome b-245, beta polypeptide
DNA-damage-inducible transcript 3 ///
nuclear receptor subfamily 1, group H,
member 3
DEAD (Asp-Glu-Ala-Asp) box
polypeptide 3, Y-linked
DnaJ (Hsp40) homolog, subfamily C,
member 10
eukaryotic translation initiation factor
1A, Y-linked
eukaryotic translation initiation factor
1A, Y-linked
eukaryotic translation initiation factor
1a, y-linked
esterase D/formylglutathione
hydrolase
haloacid dehalogenase-like hydrolase
domain containing 1A
histone cluster 1, H1c
histone cluster 1, H2bf
major histocompatibility complex, class
II, DO beta
insulin-like growth factor 1 receptor
interleukin 6 signal transducer (gp130,
oncostatin M receptor)
KIAA1683
v-myc myelocytomatosis viral
oncogene homolog 1, lung carcinoma
MTX+Et
MTX
Fold-change
MTX+Et vs
MTX
971.73
47.05
1401.44
99.97
-1.44
-2.12
226442_at
205608_s_at
298.54
254.39
646.91
308.99
201.49
1352.05
1189.48
181.19
108.77
119.43
211.52
81.19
698.59
584.64
1.65
2.34
5.42
1.46
2.48
1.94
2.03
218501_at
210538_s_at
220421_at
208796_s_at
201560_at
205898_at
203923_s_at
558.79
784.79
-1.40
209383_at
11.87
191.71
-16.16
205000_at
134.68
73.39
1.84
225174_at
10.16
214.64
-21.13
204409_s_at
10.74
113.11
-10.53
204410_at
8.38
87.36
-10.43
244482_at
278.93
182.35
1.53
209009_at
85.92
355.87
54.22
625.01
1.58
-1.76
203974_at
209398_at
412.67
613.53
-1.49
208490_x_at
133.20
1321.89
72.67
2055.06
1.83
-1.55
205671_s_at
203628_at
599.25
70.01
308.41
93.96
1.94
-1.34
212195_at
223600_s_at
90.37
62.77
1.44
214058_at
Probe set
derived (avian)
NBN
NBN
NBN
PION
PRPF4B
RBMX
TMEM77
TNFAIP3
TRAF3
XIST
XIST
XIST
XIST
XIST
XIST
ZNF644
-----
nibrin
nibrin
nibrin
pigeon homolog (Drosophila)
PRP4 pre-mRNA processing factor 4
homolog B (yeast)
RNA binding motif protein, X-linked
transmembrane protein 77
tumor necrosis factor, alpha-induced
protein 3
TNF receptor-associated factor 3
X (inactive)-specific transcript (nonprotein coding)
X (inactive)-specific transcript (nonprotein coding)
X (inactive)-specific transcript (nonprotein coding)
X (inactive)-specific transcript (nonprotein coding)
X (inactive)-specific transcript (nonprotein coding)
X (inactive)-specific transcript (nonprotein coding)
zinc finger protein 644
-----
1181.14
471.09
1523.54
239.86
669.20
264.46
852.71
119.57
1.76
1.78
1.79
2.01
202907_s_at
217299_s_at
202906_s_at
222150_s_at
190.28
335.64
216.70
134.30
240.80
144.93
1.42
1.39
1.50
202126_at
213762_x_at
225230_at
1164.22
113.85
712.15
69.29
1.63
1.64
202644_s_at
221571_at
94.04
17.10
5.50
224589_at
175.39
27.28
6.43
221728_x_at
181.17
20.63
8.78
214218_s_at
229.31
19.80
11.58
224590_at
567.32
31.47
18.03
227671_at
1231.03
70.02
133.34
136.70
51.29
44.71
79.47
79.57
24.00
1.57
1.68
1.72
224588_at
222580_at
238604_at
227682_at