YOKOHAMA CITY UNIVERSITY HOSPITAL
NOTICE OF APPROVAL OF
IRB PROTCOL NUMBER:B120510019
PRINCIPAL INVESTIGATOR: Takuma Higurashi, MD
Department of Gastroenterology,
Yokohama City Univercity
3-9 Fukuura, Kanazawaku,
Yokohama 236-0004, Japan
CO-INVESTIGATOR(S): Atushi Nakajima, MD, PhD, Hirokazu Takahashi, MD, PhD, Hiroki
Endo, MD, PhD, Eiji Sakai, MD,
TITLE: Eicosapentaenoic acid (EPA) efficacy for colorectal aberrant crypt foci (ACF)：
A double-blind
randomized controlled trial
PERFORMANCE SITE(S): Yokohama City University Hospital, Department of Gastroenterology,
Chigasaki Municipal Hospital, Gastroenterology Division, Yokohama Rosai Hospital, Department of
Gastroenterology,
TYPE OF APPROVAL: INITIAL
EXPIRATION DATE: 31/5/2017
EFFECTIVE DATE: 1/6/2012
Fumiki Hirahara, MD
Principal of Yokohama City University Hospital
Date: May 11th, 2012