Table 5: Continuous outcomes on last day of treatment from original studies (*included in pooling). Studies Number of subjects, Outcome Outcomes Included in (Author, Year) intervention measurement (mean + SD) pooling Treatment Comparator Treatment group Comparator group Belluomini Acupressure Sham Rhodes Index 5.80 ± 2.9 7.04 ± 2.6 * 1994 P6 acupressure scores N=30 point Nausea scores: 1.28 ± 1.9 1.63 ± 2.3 * Total 8.69 ± 5.0 10.03 ± 4.6 * 4.2 ± 2.6 5.9± 2.4 * 4.2 ± 2.6 6.5 ± 2.2 N = 30 Belluomini Acupressure Sham Rhodes Index 1994 P6 acupressure scores N=30 point Emesis scores: N = 30 Belluomini Acupressure Sham 1994 P6 acupressure N=30 point N = 30 Werntoft 2001 Werntoft 2001 Acupressure Sham VAS P6 acupressure Degree of nausea N = 20 N = 20 Acupressure No treatment VAS P6 N = 20 N = 20 Jamigorn 2007 Saberi 2013 nausea Acupressure Sham Rhodes index score, 4.1 ± 1.8 P6 + placebo acupressure + Improvement in tablets Vit B6 nausea, vomiting N = 33 N = 33 and retching Acupressure No treatment Rhodes Index P6 N=45 scores N = 48 Smith 2002 Smith 2002 Mean degree of 5.3 ± 2.1 * 4.25 ± 3.38 5.66 ± 3.10 * Nausea 8.03 ± 4.11 7.08 ± 3.0 * Retching 3.66 ± 2.47 4.48 ± 2.25 Total 14.56 ± 8.66 17.23 ±6.91 * Nausea 3.4 ± 3.0 3.7 ± 2.8 * Dry retching 0.8 ± 1.4 0.9 ± 1.4 Vomiting 0.9 ± 1.5 1.0 ± 1.6 3.4 ± 3.0 4.0 ± 3.3 0.8 ± 1.4 0.9 ± 1.3 Vomiting Traditional Sham acupuncture Acupuncture N = 148 N = 148 TCM Acupressure Rhodes Index Acupuncture P6 scores: N = 148 N = 148 Nausea Dry retching * Smith 2002 0.9 ± 1.5 0.9 ± 1.8 3.4 ± 3.0 5.0 ± 3.0 Dry Retching 0.8 ± 1.4 1.6 ± 1.7 Vomiting 0.9 ± 1.5 1.4 ± 2.0 1.20 ± 0.41 1.53 ± 0.68 1.20 ± 0.41 1.60 ± 0.72 Vomiting 3.53 ± 1.72 1.33 ± 1.69 Ketones 1.47 ± 1.66 0.67 ± 1.32 Main symptoms 18.4 ± 11.02 12.13 ±9.67 * 11.3 ± 9.2 * Traditional No treatment Rhodes Index acupuncture N = 149 scores N = 148 Mao 2009 Vomting Nausea Acupuncture IV fluid therapy Ketones + IV therapy + Chinese N = 30 herbal medicine N = 30 Mao 2009 Acupuncture IV fluid therapy Ketones + IV therapy + conventional N = 30 therapy N = 30 Ou 2001 Ear Chinese herbal acupressure medicine N = 30 N = 30 Puangsricharern Auricular 2008 acupressure No treatment Mean Rhodes index 7.7 ± 4.9 N = 46 Nausea and * N = 45 vomiting scores