Supplemental Digital Content 1 Coefficient of correlation between mRNA expression levels of CYP3As and age in living-donor liver transplantation a) Coefficient of correlation between hepatic mRNA expression levels of CYP3As and age of donor in living-donor liver transplantation mRNA expression levels in the grafted liver Age of donor r P value CYP3A4 mRNA -0.0771 0.1208 CYP3A5 mRNA 0.0246 0.6210 CYP3A7 mRNA -0.0195 0.6951 CYP3A43 mRNA -0.0248 0.6176 b) Coefficient of correlation between intestinal mRNA expression levels of CYP3As and age of recipient in living-donor liver transplantation mRNA expression levels in the small intestine Age of recipient r P value CYP3A4 mRNA 0.1825 0.0012 CYP3A5 mRNA 0.0169 0.7660 CYP3A7 mRNA 0.0381 0.5031 CYP3A43 mRNA -0.0259 0.6486