Table S1: Linear regression models for investigated parameters stating R², F-value and degrees of freedom. BS=Baltic Sea, IC=Iceland, rel=relative lifespan, sol.=soluble proteins, insol.=insoluble proteins, *only slopes for nucleic acid oxidation are significant Physiological Linear model R² F- parameter d.f. p-value value yDNA,BS=0.583x+7.226 0.473 17.07 1,19 pDNA,BS=0.0006 yDNA,IC=0.071x+8.932 0.440 14.12 1,18 pDNA,IC=0.0014 yRNA,BS=0.881x+8.168 0.677 39.75 1,19 pRNA,BS<0.0001 yRNA,IC=0.109x+23.1 0.370 10.59 1,18 pRNA,IC=0.0044 yrelBS,DNA=0.233x+7.226 0.473 17.07 1,19 prelBS,DNA=0.0006 yrelIC,DNA=0.212x+8.931 0.440 14.12 1,18 yrelBS,RNA=0.353x+8.168 0.677 39.75 1,19 prelBS,RNA<0.0001 yrelIC,RNA=0.327x+23.1 0.370 10.59 1,18 prelIC,RNA=0.0044 yBS=0.041x+1.068 0.045 0.567 1,12 pBS=0.4659 yIC=-0.013x+6.552 0.051 1.227 1,23 pIC=0.2794 yBS,sol.=-0.003x+2.607 0.005 0.067 1,13 pBS,sol=0.8 yIC,sol.=-0.001x+2.410 0.020 0.478 1,37 pIC,sol=0.4961 yBS,insol.=-0.018x+2.803 0.234 1.528 1,5 pBS,insol=0.2712 yIC,insol.=-0.001x+2.474 0.065 0.691 1,10 pIC,insol=0.4251 Protein stability yBS,control=0.003x+0.396 0.067 0.793 1,11 pBS,control=0.3923 0.003 0.041 1,13 pBS,stress=0.843 0.018 0.419 1,23 pIC,control=0.5237 Nucleic acids* Lipid peroxidation Protein carbonyls yBS,stress=-7.929E- prelIC,DNA=0.0014 4x+0.609 yIC,control=1.789E4x+0.402 yIC,stress=2.342E-5x+0.497 1.873E-4 0.004 1,23 pIC,stress=0.9482