Table S1: Taxonomic and collection data (clinical, geographical, biochemical and molecular Information) for L. (Viannia) strains used for MLSA.
IOC/L
Species
International code
1023
1266
855
1365
854
1939
1953
1545
3199
3200
1731
849
2139
2159
2287
2288
2291
2419
2420
2427
2467
2472
2475
2480
2510
2515
2660
2836
2838
2148
2481
2502
iz 26
iz 28
iz 31
L. lainsoni
L. lainsoni
L. naiffi
L. naiffi
L. naiffi
L. naiffi
L. naiffi
L. shawi
L. shawi
L. shawi
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
MHOM/BR/1981/M6426
MAGO/BR/1983/IM1721
MHOM/BR/1986/IM2773
MDAS/BR/1979/M5533
ISQU/BR/1985/IM2264
ISQU/BR/1994/IM3936
MHOM/BR/1994/IM4000
MCEB/BR/1984/M8408
MHOM/BR/1999/M17997
MHOM/BR/1999/M17998
MAGO/BR/1992/IM154
MHOM/BR/1987/J.CARLOS
MHOM/BR/1996/GBS
MHOM/BR/1996/JPS
MHOM/BR/1998/AFS
MHOM/BR/1996/MAS
MHOM/BR/1997/ASB
MHOM/BR/1999/JAS
MHOM/BR/1999/PCS
MHOM/BR/1999/SJB
MHOM/BR/2001/LTCP14182
MHOM/BR/2001/LTCP13455
MHOM/BR/2001/LTCP14214
MHOM/BR/2001/LTCP13980
MHOM/BR/2000/CEA
MHOM/BR/2001/TSS
MHOM/BR/2004/ARARAQUARA-1
MHOM/BR/1994/LTCP9845
MHOM/BR/1997/LTCP11245
MHOM/BR/2001/VLNC
MHOM/BR/2000/LTCP13490
MHOM/BR/2002/NMT-RBO040
MORY/PE/84/AO23
MRAT/PE/84/A1
MORY/PE/84/AC20
Geographic
origin
(Brazilian
state)
PA
PA
AM
PA
PA
AM
AM
PA
PA
PA
RO
RJ
PB
RJ
PE
PE
PE
PE
PE
PE
BA
BA
BA
BA
PE
PE
SP
BA
BA
PE
BA
AC
-
Clinical form
CL
CL
*
VL
*
*
CL
CL
*
*
CL
MCL
CL
CL
CL
CL
MCL
CL
CL
CL
DL
CL
CL
MCL
CL
CL
CL
CL
CL
MCL
CL
CL
*
*
*
Zymodeme MPI
15
15
36
36
38
49
49
26
*
*
53
27
27
27
72
45
73
73
45
74
27
27
27
27
27
78
27
27
27
105
27
82
*
*
*
1
2
3
4
4
4
4
5
5
5
6
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
G6PD
6PGD
ICD
DST
CC
1
1
2
3
7
7
7
4
4
4
5
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
2
2
1
28
6
6
7
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3; 4
3
10
3
5
8
9
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
11
14
25
40; 41
40; 41
42
1
2
3
4
5
6
7
8
9
10
11
12
12
12
12
12
12
12
12
12
12
12
12
12
12
12
12
12
12
13
14
15
16
16
17
CC1
CC1
singl
htz
CC2
CC2
CC2
CC3
CC3
CC3
singl
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
CC4
htz
htz
CC4
IOC/L
Species
International code
iz 27
2491
2535
2344
2693
2495
2950
2494
1734
2509
2929
iz 33
2833
2951
2511
2499
2468
iz 18
2466
2476
2847
2152
565
2963
2937
2971
2969
2334
2341
2350
2970
2936
2938
2956
2957
2961
2962
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. guyanensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
L. guyanensis
MORY/PE/84/AO8
MHOM/BR/2002/NMT-RBO 005
MHOM/BR/2001/HC-JS
MHOM/BR/1997/NMT-MAO 229P
MNEC/BR/2003/NECTOMYS
MHOM/BR/2002/NMT-RBO025
MHOM/BR/2006/CEN
MHOM/BR/2002/NMT-RBO 018
MHOM/BR/1991/IM3713
MHOM/BR/2001/CRFN
MHOM/BR/2005/NMT-LTCP16011-P
MORY/PE/84/ABR23
MHOM/BR/2001/LTCP14349
MHOM/BR/2006/CM
MHOM/BR/2001/JS
MHOM/BR/2002/NMT-RBO 035
MHOM/BR/2001/LTCP14183
MCHO/BR/80/M6202
MHOM/BR/2001/LTCP13183
MHOM/BR/2001/LTCP14278
MHOM/BR/2002/LTCP15476
MHOM/BR/1996/AFN
MHOM/BR/1975/M4147
MHOM/BR/2007/033-MECM
MHOM/BR/2007/065
MHOM/BR/2007/021-R
MHOM/BR/2007/AC
MHOM/BR/1997/NMT-MAO 202P
MHOM/BR/1997/NMT-MAO 223P
MHOM/BR/1997/NMT-MAO 237P
MHOM/BR/2007/021-HMB
MHOM/BR/2007/069
MHOM/BR/2007/063
MHOM/BR/2007/011
MHOM/BR/2007/014-JIS
MHOM/BR/2007/019-WDSN
MHOM/BR/2007/031-LOP
Geographic
origin
(Brazilian
state)
AC
ES
AM
PE
AC
PE
AC
AM
PE
BA
BA
PE
PE
AC
BA
*
BA
BA
BA
RJ
PA
AM
AM
AM
AM
AM
AM
AM
AM
AM
AM
AM
AM
AM
AM
Clinical form
*
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
*
MCL
CL
CL
CL
MCL
*
CL
DL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
CL
Zymodeme MPI
*
78
27
*
74
78
75
80
35
74
27
*
27
75
105
81
27
*
27
27
27
27
23
23
23
23
23
23
23
23
23
23
23
23
23
23
23
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
7
8
8
8
8
8
9
9
9
9
9
9
9
9
9
9
9
9
9
9
9
G6PD
6PGD
ICD
DST
CC
6
6
6
6
6
6
6
6
6
18
18
18
18
19
11; 16
12; 13
6; 11
4
6
6
6
6
4
4
4
4
4
8
9
10
10
22
23
24
25
27
28
1
8
8
10
12
12
17
1; 11
4; 5
1
1
1
1; 8
17
1
1
1
9
1
1
1
8
9
9
9
9
26
9
9
9
9
9
19
9
9; 20
22
23
6; 41
16
12; 27
6
6
19
33
18
7
6
6
6; 41
6
33
6
23
6
9
6
6
6
12
9
13
30
37
30
9
9
13
36
9
31; 32
9
9
9
35
18
19
20
21
22
23
24
25
26
27
27
28
29
30
31
32
33
34
35
35
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
htz
singl
htz
CC4
CC4
CC4
CC5
htz
htz
CC4
CC4
htz
htz
CC5
htz
htz
htz
CC6
CC4
CC4
CC4
singl
CC6
CC6
CC6
CC6
CC6
CC6
CC6
CC6
CC6
CC6
htz
CC6
htz
singl
singl
IOC/L
Species
International code
2966
iz 34
2490
2493
2497
2498
2500
2501
2503
566
921
918
2538
2541
2689
2690
2960
2964
992
995
iz 35
iz 25
2463
2571
L. guyanensis
L. guyanensis
L. lainsoni/ L. naiffi
L. guyanensis
L. lainsoni
L. braziliensis
L. lainsoni
L. braziliensis
L. lainsoni
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. braziliensis
L. utingensis
L. lindenbergi
L. guyanensis
L. guyanensis
L. naiffi
L. naiffi
L. lainsoni
L. lainsoni
L. braziliensis
L. braziliensis
MHOM/BR/2007/039
MCHO/BR/80/M6200
MHOM/BR/2002/NMT-RBO004
MHOM/BR/2002/NMT-RBO 013
MHOM/BR/2002/NMT-RBO 027P
MHOM/BR/2002/NMT-RBO 029
MHOM/BR/2002/NMT-RBO036
MHOM/BR/2002/NMT-RBO037
MHOM/BR/2002/NMT-RBO044
MHOM/BR/1975/M2903
MHOM/BR/1987/H-210
MRAT/BR/1987/C18.454
MHOM/BR/2002/EMM
MHOM/BR/1999/MJAA-II
ITUB/BR/1977/M4964
MHOM/BR/1966/M15733
MHOM/BR/2007/029-ZAV
MHOM/BR/2007/034-MFPS
MDAS/BR/1987/IM3280
MDAS/BR/1987/IM3292
IUBI/BR/00/M12025
MHOM/BR/82/M6887
MHOM/BR/2001/JOLIVAL
MHOM/BR/2003/NJS
Geographic
origin
(Brazilian
state)
AM
*
AC
AC
AC
AC
AC
AC
AC
PA
CE
CE
RJ
PE
PA
PA
AM
AM
PA
PA
PA
PA
BA
MS
Clinical form
CL
*
CL
CL
CL
CL
CL
CL
CL
CL
CL
VL
CL
CL
*
CL
CL
CL
VL
VL
*
*
MCL
CL
Zymodeme MPI
23
*
87
110
86
84
86
79
86
27
27
27
27
74
101
102
23
23
42
36
*
*
27
7
G6PD
9
29
9
4; 33
11
14
12
4
13
1
14
15
15
17
16
6
17
14
18
6
18
6
18
6
18
19
19
6; 16
20
20
21
21
22
26
23
4
24
30
24 30; 31
25
1
25
1; 32
7; 10 6; 11
7; 8
6
6PGD
ICD
24; 25
9
32
9
2
15
9
17
13
20; 21
14
22
1
24
15
6
16
26
1
11
27
11
8; 11
11
8; 17 6; 11
1
6
18
28
1
29
21
34
9
9
28
3
29
38
33
43
30; 31
39
1
6
1
6
DST
CC
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
htz
htz
singl
singl
htz
singl
singl
singl
singl
CC4
CC4
htz
htz
htz
singl
singl
singl
singl
singl
htz
singl
htz
htz
htz
From the left: IOC/L (Institute Oswaldo Cruz Leishmania Collection) – culture collection code; Leishmania species; International code – see WHO, 2010 for description, BR=
Brazil and PE= Peru; Brazilian states – AC: Acre, AM: Amazonas, BA: Bahia, CE: Ceará, PA: Pará, PB: Paraíba, PE: Pernambuco, ES: Espírito Santo, MS: Mato Grosso do Sul, RJ:
Rio de Janeiro, RO: Rondônia, SP: São Paulo; clinical form observed in the host: VL – visceral leishmaniasis, CL – cutaneous leishmaniasis, MCL – mucocutaneous
leishmaniasis; zymodemes according to the CLIOC system ; sequence types observed for each marker; DST: diploid sequence type; CC: clonal complexes formed after eburst analysis; singl: singletons after e-burst analysis; htz: heterozygous strains – not included in the e- burst analysis. * Information not available.