Supplementary Table 2.Univariate analyses of risk factors for intestinal GVHD (≥grade 2)
Univariate variables
Age of patient (y),
continuous
Sex of patient
Male
Female
Sex pair (donor-recipient)
Female to male
Others
Donor Type(1)
Sibling
Unrelated
Sources of graft
BM
PBSC
Pre-SCT disease status
Standard
Advanced*
ATG given as conditioning
Yes
No
Conditioning regimen
TBI based
Non-TBI based
GVHD prophylaxis
CS based
FK506 based
ABO match
Match
Mismatch
T cell/MDSC ratio†
Low
High
Multivariate variables
RR (95% CI)
P
0.97 (0.92-1.02)
0.259
1
1.50 (0.46-4.90)
0.498
1
8.16 (0.97-68.7)
0.054
1
2.31 (0.73-7.28)
0.154
1
1.41 (0.41-4.83)
0.586
1
2.31 (0.68-7.89)
0.183
1
1.47 (0.77-4.56)
0.508
1
1.25 (0.36-4.31)
0.726
1
2.31 (0.73-7.28)
0.154
1
1.18 (0.38-3.67)
0.770
1
3.79 (1.10-13.04)
0.035
RR (95% CI)
P
Sex pair (donor-recipient)
Female to male
1
Others
13.32 (1.37-129.6)
0.026
T cell/MDSC ratio†
Low
1
High
6.13 (1.52-24.7)
0.001
Abbreviations; ATG, antithymocyte globulin; BM, bone marrow; CS, cyclosporine; F, female; GVHD, graftversus-host disease; M, male; PBSC, peripheral blood stem cell; TBI, total body irradiation; y, year-old.
* Advanced disease status at transplantation includes acute leukemia beyond the first remission, high-risk
myelodysplatic syndrome (international prognostic scoring systemintermediate-2)
† Low vs. High grouped by median value of T cell/MDSC ratio