RTC 14/15 2D College of Science and Engineering POSTGRADUATE RESEARCH PROGRAMME PROPOSAL PhD with Integrated Study in Optical Medical Imaging with Healthcare Innovation and Entrepreneurship The College Research and Training Committee is asked to approve the new programme of “PhD with Integrated Study in Optical Medical Imaging with Healthcare Innovation and Entrepreneurship”. Rationale The University recently approved the degree title of “PhD with Integrated Study”, for which the regulatory framework is given in Appendix 1. This paper contains a proposal for an award, “PhD with Integrated Study in Optical Medical Imaging with Healthcare Innovation and Entrepreneurship”. This award is related to the funding by EPSRC of a Centre for Doctoral Training (CDT) in Optical Medical Imaging, a collaboration between the School of Chemistry (SoC), the School of Engineering (SoE), the Business School (Biz) and the College of Medicine and Veterinary Medicine (CMVM) at Edinburgh, and the University of Strathclyde (UoS). Structure of the programme Background The EPSRC and MRC CDT in Optical Medical Imaging has been established to ensure that the UK has a strong and sustained pipeline of future scientific leaders and innovators in optical medical imaging encompassing the molecular, cellular, preclinical and clinical applications of physical and biomedical science in this priority area. 60 PhD students will be recruited over the following five years with the programme running for eight years. The PIs are Professor Mark Bradley (Edinburgh) and Professor Duncan Graham (Strathclyde) and the CDT will be run on a day-by-day basis by the CDT Director Dr Colin Campbell, School of Chemistry, University of Edinburgh. Establishment of a new degree program A key element of the CDT training program is the establishment of a 4-year PhD with Integrated Study in Optical Medical Imaging with Healthcare Innovation and Entrepreneurship. This degree will be awarded jointly by the Universities of Edinburgh and Strathclyde. The degree will be formally owned by the School of Chemistry at the University of Edinburgh. However the degree program is delivered jointly by the School of Chemistry, College of Medicine and Veterinary Medicine, School of Engineering and Business School at the University of Edinburgh and the Department of Pure and Applied Chemistry, Strathclyde Institute of Pharmacy and Biomedical Sciences, The Department of Physics and the Hunter Centre at the University of Strathclyde. Page 1 of 13 RTC 14/15 2D Multidisciplinary projects and training CDT projects and training will cover multiple areas of engineering, optics, chemistry and biology and business with all PhD students assigned a supervisory committee including at least one supervisor from CMVM, one from UoS, one from SoC and one from SoE thus ensuring a strong clinical pull and underlining the multidisciplinary ethos of the CDT. The CDT involves over 30 potential PhD supervisors, and PhD students will benefit from summer schools, industrial placements, clinical mentors and a bespoke course in Healthcare Innovation and Entrepreneurship delivered in partnership with the University of Edinburgh Business School, the University of Strathclyde’s Hunter Centre (HC) and our industrial partners. Regulations The University of Edinburgh’s Degree Regulations and Programmes of Study and Postgraduate Assessment Regulations for Research Degrees will apply. Progression The following procedures will cover the monitoring of student progress for all of the students within the CDT. These are the only procedures that will be used for monitoring student progress and assessment and CDT students will not be required to fulfil any additional requirements of the graduate school of their principal supervisor. The CDT will inform the School of Chemistry’s Graduate School that reviews have taken place and are satisfactory. If a student’s review is not satisfactory, the CDT will provide evidence to the Graduate School that an action plan is in place. Students will be formally assessed by their supervisory committee and the Director: (i) 3 months - all students will write a fifteen-page review on their research area and present this to their PhD panel. (ii) 10 months - students will present a thirty-page report that details their progress, including a detailed overview of their training accomplishments and their plans for outreach activities in years two and three, followed by a viva. If the committee agree that progress is suitable at this stage the student will be formally transferred to the PhD register. (iii) 24 months - students will prepare a short summary of their accomplishments and objectives, prepare a draft publication to shape future research, and present their training portfolios at a viva. (iv) 36 months - students will submit a summary of their accomplishments, present an oral report their 3-month placements and prepare thesis plans and abstracts. (v) 48 months - students will submit a thesis and undergo a viva. In addition, during second year students are required to present a poster and during third year students are required to carry out an oral presentation to their peers, supervisors and the scientific advisory committee at the annual summer school. These assessment criteria are compatible with the assessment criteria of all partners and students will not be required to carry out additional assessments within the graduate schools of their individual supervisors. Lab demonstration or tutoring Students will be eligible to perform tutoring or demonstrating duties in the institution of their principal supervisor, in line with local regulations. The taught elements of the programme The organisation responsible for delivery of the taught elements is indicated in brackets (Biz - UoE Business School; Soc – UoE School of Chemistry; CMVM – UoE College of Medicine and Veterinary Medicine; HC – UoS Hunter Centre; PAC – UoS Department of Pure and Applied Chemistry). Page 2 of 13 RTC 14/15 2D The majority of courses already exist and have associated QA documentation and assessment criteria. The exceptions are Ethics and Regulation, Build Your Own Microscope and Translational Study (see appendix for course descriptions). Core Modules at SCQF Level 11 (Students take all of the following) Optical Medical Imaging Grand Challenge. (SoC) Placement (SoC) Innovation Driven Entrepreneurship (Biz) Translational Study - Innovation and Entrepreneurship Masterclass (Biz) Ethics and Regulation (CMVM) Technology Commercialisation Workshop (Biz-HC) Build your own microscope (PAC) 20 Credits 60 Credits 20 Credits 20 Credits 15 Credits 10 Credits 5 Credits Electives at SCQF Level 11 (Students take 2 from the following) Entrepreneurial Challenge (Biz) The Entrepreneurial Manager (Biz) Marketing (Biz) Accounting and Finance (Biz) 15 Credits 15 Credits 15 Credits 15 Credits Representative timetable Sept Oct Nov Dec Jan Feb Mar Apr May Jun Jul Aug Year 1 Grand Challenge (20 Credits) Innovation Driven Entrepreneurship (20 Credits) Build your own microscope (5 credits) Year 2 Ethics Regulation and Healthcare (15 Credits) Translational Study - Masterclass (20 Credits) Year 3 Elective 1 (15 Credits) Tech Comm Workshop (10 Credits) Placement (60 Credits) Year 4 Elective 2 (15 Credits) Final award Students must pass a minimum of 140 credits with a pass mark of at least 50% and attain an average of at least 50% overall for the 180 credits of taught programme and pass the PhD viva to be awarded the PhD with Integrated Study in Optical Medical Imaging with Healthcare Innovation and Entrepreneurship. Students who pass the PhD viva but do not pass the required taught components will be eligible for the award of a standard PhD from the institution of their primary supervisor. Students who fail the PhD viva may be eligible to submit for a Master of Science by Research (MScR) in the institution of their principal supervisor. Page 3 of 13 RTC 14/15 2D Students who are found to be making unsuitable progress at the 10 month monitoring point may be asked to submit for a MScR in the institution of their principal supervisor. Fees Fees will be standard University of Edinburgh PhD fees. The FTE and fee split will be as stated in the Memoranda of Agreement related to the CDT in Optical Medical Imaging. Page 4 of 13 RTC 14/15 2D Appendix 1: Regulatory framework for the PhD with Integrated Study The degree programme should comprise a total of 720 credits, of which at least 540 should be at SCQF level 12 (thus equivalent to the PhD) and at least 690 at SCQF level 11 or above (thus ensuring that taught components are consistent with the requirements for Masters). The prescribed period should be for four years with a further “writing-up” period of up to 12 months (pro-rata for part-time study), where permitted by the external sponsor. (For EPSRC only, the submission due date for student theses is calculated as end date of funding plus one year.) The programme PhD with Integrated Study should be available, subject to approval by the relevant College Committee, to a cohort of students following a programme which requires a structured programme of study which integrates research with assessed taught postgraduate training in a range of skills and subject focused modules, up to a maximum of 180 credits. The outcome of the assessment of the training and skills component may be used in determining progression on the programme, or eligibility for an exit award at Masters/Diploma/Certificate level, providing that the student has attained the requirements for the award as set out in the University regulations. For the award of PhD with Integrated Study, the research component must meet the assessment criteria for a PhD in the current University regulations. Page 5 of 13 RTC 14/15 2D Appendix 2: Course description for Ethics and Regulatory Processes in Translating Innovation from Bench to Man Course name: Ethics and Regulatory Processes in Translating Innovation from Bench to Man Owning school: CMVM Home subject area: CMVM UG or PG: PGR Visiting students only?: N Credit points: 15 Credit level: 11 Session course operational from: 2015 S1, S2, or full year? S2 Short description of course (max 2000 characters): Ethics and Regulatory Processes in Translating Innovation from Bench to Man is a course which blends formal lectures, mentorship and a problem-based learning exercise. The course will comprise 6 hours of lectures and an exercise with 2 assessed components (a peer assessed wiki and a presentation) to answer a clinically-relevant translational challenge. The lecture series will cover the principles of GCP/GMP, Regulatory submissions, Trial design, Ethical Board applications and general challenges in introducing technologies in to patients. The course is split into two phases: Phase 1 is an intensive one-day workshop mixing formal lectures by external experts with Q&A sessions and group discussions. Lectures will be delivered by expert speakers from regulatory consultancies, clinicians, quality assurance and the pharmaceutical industry. Phase 2 is a 6 week problem-based exercise where students in small groups are tasked with the generation of a WIKI page Page 6 of 13 RTC 14/15 2D detailing the context and suggested approach for an ethical/regulatory issue in technology development. Each group will be assigned a staff mentor. Students will see their mentors weekly for a maximum of one hour. The students will present their wiki to their peers and mentors to assess their approaches to the regulatory challenge. The assessment will generate new ideas and provide feedback to the students to refine and improve their strategy before they make their final presentation. The final presentation will be judged by the students’ mentors and the expert lecturers. After the presentations the students will receive further feedback from the external lecturers. Pre-requisite courses, if any (only logic operations on named courses can be specified here): Students must be enrolled on a PhD in the EPSRC and MRC CDT in Optical Medical Imaging. Co-requisite course: None Prohibited courses, if any (only logic operations on named courses can be specified here): None Other free-text entry conditions (if any) e.g. minimum mark, only for VUGs: This course is not open to undergraduates. Scheduled class hours: To be arranged Other attendance information: None Summary of intended learning outcomes (max 2000 characters): At the end of this course students will be able to: Understand an ethical/regulatory research problem from a variety of perspectives including scientific, commercial and social. Understand the basic principles of GCP Critically assess other people’s approaches to solving significant scientific and regulatory challenges. Develop a WIKI page and web-based skills to Page 7 of 13 RTC 14/15 2D communicate knowledge of the ethical/regulatory issues. Have a broad understanding of the ethical/regulatory challenges of translating technology from bench to man. Learning outcomes specific to attainment of a pass at Level 11 include: - ability to integrate all, or most, of the main areas of the course - development of original and creative responses to problems and issues within the course - application of critical analysis, evaluation and synthesis to issues at the forefront of the subject area Assessment information (free text) This course will be assessed first through the development of a web-based resource (wiki). Assessment of the wiki will be peer assessment. The final assessment will be on the basis of a presentation. Assessment of the presentation will be by a panel of external experts and the students’ mentors. Course organiser: Dr Kev Dhaliwal Course secretary: To be confirmed Default course mode of study: Main exam diet (Dec or Apr): n/a Exam requirements: n/a Page 8 of 13 RTC 14/15 2D Appendix 3: Course description for Translational Study Course name: Translational Study - Innovation and Entrepreneurship Masterclass (Biz) Owning school: Business Home subject area: Business UG or PG: PGR Visiting students only?: N Credit points: 20 Credit level: Level 11 Session operational from: course 2016/17 S1, S2, or full year? To be arranged Short description of The Translational Study is a student-led, independent study course (max 2000 course designed to promote student exposure to the characters): challenges and opportunities associated with translating innovation into a market context. The course builds on the outcomes of the Grand Challenge and Innovation-Driven Entrepreneurship (IDE) courses. Students are encouraged to work in small teams, but may choose to work independently to investigate a specific innovation of personal interest. Each team is assigned a staff member. Teams are expected to meet with that staff member approximately one hour each week. The course is split into three phases: 1) ideation, 2) development research, and 3) entry evaluation. Phase 1, ideation, is a 2 week activity in which the teams explore a limited set of innovations related to their research studies. Teams may build on innovations explored during Grand Challenge / IDE or may investigate a novel innovation. Teams will be encouraged to select an innovation with relatively near-term product potential or short development timeframe. At the end of this phase teams present their findings and will be assessed on the content and delivery of their presentations. Page 9 of 13 RTC 14/15 2D In Phase 2, the teams conduct primary research on the industry and market relevant to the anticipated product. Students will be encouraged to engage with industry participants to better understand customer needs, product development requirements, manufacturing parameters, and distribution and support processes. This phase is expected to require 4 weeks, depending on access to industry participants and/or customers. At the end of this phase teams submit a short report on market feasibility. Phase 3, entry evaluation, is a 4 week activity in which teams identify the resources and processes necessary to bring the product to market. At the end of the phase, teams present their analysis, including a final recommendation regarding commercialization path. Teams will be assessed on the content and delivery of their presentations. Pre-requisite courses, if Students must be enrolled on a PhD in the EPSRC and MRC any (only logic operations CDT in Optical Medical Imaging. Students must have on named courses can be completed the Grand Challenge and IDE. specified here): Co-requisite course: None Prohibited courses, if any None (only logic operations on named courses can be specified here): Other free-text entry This course is not open to undergraduates. conditions (if any) e.g. minimum mark, only for VUGs: Scheduled class hours: Other information: To be arranged attendance None Summary of intended At the end of this course students will be able to: learning outcomes (max Work effectively in teams and understand the various 2000 characters): roles that individuals can play in teams. Understand the specific challenges associated with translating a research-driven innovation into a Page 10 of 13 RTC 14/15 2D Assessment (free text) commercial context. Conduct primary research on market needs and new product requirements. Describe the general stages of technology commercialization, including different organizational forms and resource requirements. Communicate the results of market and industry research to both scientific and business audiences. Critically assess the potential commercial value of a novel innovation for a specific market need. information This course will be assessed at Phases 1 and 3 through presentations. The written report submitted at the end of Phase 2 will be marked by two members of the CDT team. Course organiser: To be confirmed Course secretary: To be confirmed Default course mode of study: Main exam diet (Dec or n/a Apr): Exam requirements: n/a Page 11 of 13 RTC 14/15 2D Appendix 4: Course description for Build your own microscope Course name: Build your own microscope Owning school: University of Strathclyde Home subject area: Physical Sciences UG or PG: PGR Visiting students only?: N Credit points: 5 Credit level: Level 11 Session operational from: course 2014/15 S1, S2, or full year? Summer Short description of “Build your own microscope” is a hands-on course in which course (max 2000 groups of students are given the necessary components to characters): build a microscope. The course will be led by Professor Neil Shand of DSTL who will teach the students through a variety of lectures, workshops and independent study exercises how to assemble a fully functional microscope. Pre-requisite courses, if Students must be enrolled on a PhD in the EPSRC and MRC any (only logic operations CDT in Optical Medical Imaging. on named courses can be specified here): Co-requisite course: None Prohibited courses, if any None (only logic operations on named courses can be specified here): Other free-text entry This course is not open to undergraduates. conditions (if any) e.g. minimum mark, only for VUGs: Scheduled class hours: Other information: To be arranged attendance None Summary of intended At the end of this course students will be able to: learning outcomes (max Work effectively in teams and understand the various Page 12 of 13 RTC 14/15 2D 2000 characters): Assessment (free text) roles that individuals can play in teams. Understand how fundamental physical sciences can be applied to build a functional microscope. information This course will be assessed continuously by Professor Shand and Dr Faulds. Students will be assigned a mark based on their level of engagement, effort and understanding of the task and their ability to build a functional microscope. Feedback will be given to the students throughout the exercise in order to ensure that the key points covered in lectures and workshops have been understood and are being used in the successful design and build of a functional microscope. Course organiser: Dr Karen Faulds Course secretary: To be confirmed Default course mode of study: Main exam diet (Dec or n/a Apr): Exam requirements: n/a Page 13 of 13