Supplementary Material
Synthesis, spectroscopic characterization, thermal stability and biological
studies of mixed ligand complexes of gemifloxacin drug and 2,2'-bipyridine
with some transition metals
Sadeek A. Sadeek• Sherif M. Abd El-Hamid• Walaa H. El-Shwiniy
S. A. Sadeek () ● S.M. Abd El-Hamid ● Walaa H. El-Shwiniy
Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt
e-mail: s_sadeek@zu.edu.eg, Tel.: +20 01220057510; fax: +20 0553208213.
Infrared
spectra
for
(A)
GMFX;
(B)
Bipy,
(C)
[Zn(GMFX)(Bipy)(H2O)2](CH3COO)2.H2O,
(D)
(E)
[Pd(GMFX)(Bipy)(H2O)2]Cl2.H2O,
[Ce(GMFX)(Bipy)(H2O)2](SO4)2.3H2O,
(F)
[ZrO(GMFX)(Bipy)Cl]Cl.2H2O,
(G) [Th(GMFX)(Bipy)(H2O)2](NO3)4.3H2O and (H) [UO2(GMFX)(Bipy)](CH3COO)2.3H2O.
Electronic
absorption
spectra
for
(A)
[ZrO(GMFX)(Bipy)Cl]Cl.2H2O,
(B)
[Pd(GMFX)(Bipy)(H2O)2]Cl2.H2O,
(C)
[Ce(GMFX)(Bipy)(H2O)2](SO4)2.3H2O, (D) [Th(GMFX)(Bipy)(H2O)2](NO3)4.3H2O and (E) [UO2(GMFX)(Bipy)](CH3COO)2.3H2O.
Mass
spectra
diagrams
for
for
(A)
[Zn(GMFX)(Bipy)(H2O)2](CH3COO)2.H2O,
(B)
[ZrO(GMFX)(Bipy)Cl]Cl.2H2O,
(C)
[Pd(GMFX)(Bipy)(H2O)2]Cl2.H2O,
(D)
[Ce(GMFX)(Bipy)(H2O)2](SO4)2.3H2O,
(E)
[Th(GMFX)(Bipy)(H2O)2](NO3)4.3H2O
and (F) [UO2(GMFX)(Bipy)](CH3COO)2.3H2O.
The diagrams of kinetic parameters of gemifloxacin, 2,2'-bipyridine and their
complexes using Coats-Redfern (CR) and Horowitz-Metzger (HM) equations.
160
140
120
100
80
60
40
20
0
E. coli
C. albicans
P. aeruginosa
A. awamori
B.subtilis
Alternaria sp
S. aureus
Statistical representation for biological activity of gemifloxacin, 2,2'-bipyridine
and its metal complexes.