Supporting Information for: “The Geographic Distribution and Economic Value of Climate-Related Ozone Health Impacts in the United States in 2030” Authors: Part 1: Health Impact Assessment Estimating air quality concentrations across the population To quantify the level of ozone among populations in each 36km grid cell, we started with 2010 U.S. Census block-level population data and aggregated population counts to the 36km CMAQ model cells in BenMAP-CE across the continental U.S. This software contains the appropriate age, sex and race stratification that corresponds to the demographic characteristics of the concentrationresponse relationship specified in the impact function. Using an economic forecasting model, we next projected this national population data to the year 2030, which corresponds to the projected years for the air quality modeling scenarios (Woods and Poole 2012). We estimated the climateattributable summer-season ozone levels among populations in each grid cell by calculating the difference between each baseline and model projected ozone levels. Selection of concentration-response relationships and baseline incidence rates For each sector we assessed the number of ozone-related premature deaths and non-fatal illnesses using concentration-response functions that are drawn from the peer reviewed literature (See Supplemental Material, Table 1) that are generally consistent with recent EPA analyses and other health impact assessments using BenMAP (EPA 2011; Fann et al. 2011). Finally, we applied baseline incidence rates matched to each health endpoint; these rates are generally consistent with recent EPA analyses (EPA 2011) (See Supplemental Material, Table 2). When quantifying the number of deaths, we apply all-cause baseline mortality rates that have been projected to 2030 using an approach described in US EPA (2012). Calculating health impacts To quantify the number of ozone-related deaths and illnesses, for each health endpoint we applied the health impact function summarized in Table 1 below. This procedure generates counts of premature deaths and illnesses for each climate scenario. We also employ a Monte Carlo approach to calculate a distribution around each point estimate, using the standard error reported in each epidemiological study; we report the 95th percentile confidence interval from this distribution. All ozone-related premature deaths are estimated to occur in the year 2030. Page 1 of 6 Part 2: Supplemental Figures and Tables Supplemental Material, Table 1. Ozone-Related Health Endpoints and Studies Included Endpoint Study Study Population Risk Estimate (95th Percentile Confidence Interval)A Premature death Daily time series Bell et al. (2004) (non-accidental) Huang et al. (2004) (cardiopulmonary) Schwartz (2005)(non-accidental) Bell et al. (2005)(all-cause) Ito et al. (2005) (non-accidental) Levy et al. (2005) (all-cause) β=0.000390 (0.000133) β=0.000813 (0.000259) All ages β=0.000426 (0.000150) β=0.000794 (0.000212) β=0.001173 (0.000239) β=0.001119 (0.000179) Hospital Admissions Pooled using random/fixed effects: Schwartz (1995)—ICD 460–519 (all resp) Respiratory Schwartz ( 1994a, 1994b)—ICD 480–486 (pneumonia) Moolgavkar et al. (1997)—ICD 480–487 (pneumonia) Schwartz (1994b)—ICD 491–492, 494–496 (COPD) Moolgavkar et al. (1997)—ICD 490–496 (COPD) Burnett (2001) >64 years RR = 1.20 (1.06 – 1.37) per 50 µg/m3 RR = 1.07 (1.00 – 1.15) per 50 µg/m3 RR = 1.22 (1.02 – 1.47) per 50 µg/m3 Increase = 5.7% (2.5% – 8.9%) per 15 ppb RR=1.57 (2.06—1.020) per 1 ppb Increase = 4.2% (-1.0% – 9.4%) per 15 ppb <2 years Increase = 33.0 (t-statistic 3.44) per 45.2 ppb Pooled using random/fixed effects: Asthma-related ER visits Peel et al. (2005) All ages Wilson et al. (2005) Other Health Endpoints Pooled estimate: School absence days Gilliland et al. (2001) 5–17 years Chen et al. (2000) Minor Restricted Activity Days (MRADs) Ostro and Rothschild (1989) 18–65 years RR = 1.022 (0.996 – 1.049) per 25 ppb β=0.010 (0.0090) β=0.0060 (0.0110) Increase = 16.3% (-2.6% - 38.9%) per 20 ppb β= 0.015763454 (0.0049851) β=0.00741 (0.00070) Values in this column reflect the information reported by each study. When calculating health impacts, relative risk estimates were subsequently converted to beta coefficients. A Page 2 of 6 Supplemental Material, Table 2. Baseline and Prevalence Rates for Included Morbidity and Mortality Endpoints Rates Endpoint Parameter Mortality Daily or annual mortality rate Hospitalizations Daily hospitalization rate Asthma ER Visits Daily asthma ER visit rate School Loss Days Rate per person per year, assuming 180 school days per year Minor RestrictedActivity Days Daily MRAD incidence rate per person a b c d Value Sourcea Age-, cause-, and countyspecific rate Centers for Disease Control (2008) (rates for 2004–2006) Age-, region-, and causespecific rate Agency for Healthcare Research and Quality (2007) Age- and region- specific visit rate Agency for Healthcare Research and Quality (2007) 9.9 0.02137 NCHS (1996) Adams et al. (1999) Table 41 Ostro and Rothschild (1989) Healthcare Cost and Utilization Program (HCUP) database contains individual level, state and regional-level hospital and emergency department discharges for a variety of ICD codes. See ftp://ftp.cdc.gov/pub/Health_Statistics/NCHS/Datasets/NHDS/. See ftp://ftp.cdc.gov/pub/Health_Statistics/NCHS/Datasets/NHAMCS/. Lower respiratory symptoms are defined as two or more of the following: cough, chest pain, phlegm, and wheeze. Supplemental Material, Table 3. Economic unit values Supplemental Figure 1. Additional Ozone-Related Deaths in GISS/RCP 6.0 by Projected Population Page 3 of 6 Central Estimate of Value Per Statistical Incidence for 2024A ICLUS B2 2050 ICLUS A1 2050 Woods & Poole ICLUS B2 2030 ICLUS A1 2030 2030 Least, Moderately and Most Conducive Years Forming Ozone Health Endpoint Derivation offor Distributions of Estimates NCA Average of Least Moderately Most Premature death Region Three Years The EPA currently (2035) recommends (2027) (2025) a central VSL of $4.8 million (1990$, Northwest -22 -21 1990 income) based -17 on a Weibull -26 distribution fitted to 26 published VSL estimates (5 Great Plains 21 -26 -44 132 Value of a contingent valuation and 21 labor market studies). The $9,900,000 35 63 parameters, and other 95 StatisticalSouthwest Life underlying -53 studies, the distribution useful information are available in Appendix B of the EPA’s Midwest 41 11 -21 134 Guidelines for Preparing Economic Analyses (U.S. EPA, Southeast -23 -97 7 21 2010). Northeast -16 -39 7 -15 Hospital visits Northwest -19 -19 information available. -16 -23 No distributional The COI estimates (lost earnings plus direct medical costs) are based on ICD-9 Great Plains 18 -19 -37 109 Chronic Lung code-level information (e.g., average hospital care costs, Southwest -49 60 83 $22,000 31 Disease (18–64) average length of hospital stay, and weighted share of total Midwest 43 140 chronic lung11illnesses) reported-21 in Agency for Healthcare Southeast -20 -86Quality (2007) (www.ahrq.gov). 2 23 Research and No distributions available. The COI point estimates (lost Northeast -14 -35 4 -10 earnings plus direct medical costs) are based on ICD-9 Northwest -18 -18 -16 -21 All respiratory code level information (e.g., average hospital care costs, $36,000 13 -17 of hospital stay, and -33 weighted share of90 (ages 65+)Great Plains average length total Southwest 28 55 respiratory-49 category illnesses) reported in Agency for79 Healthcare Research and Quality, 2007 (www.ahrq.gov). Midwest 37 9 -20 122 No distributional information available. Simple average of Southeast Emergency -21 -82 0 17 two unit COI values (2000$): Department Visits $430 Northeast -10 -28 Smith et al. (1997)3 and -5 (1) $310, from for Asthma (2) $260, from Northwest -25 -24 Stanford et al. (1999). -20 -32 Respiratory Great Ailments Not Requiring Hospitalization Plains 27 -38 -60 178 No distribution on (1) the probability that, Southwest 51 -69 available. Based 87 135 if a school child stays home from school, a parent will have School Loss Days $98 46 Midwest 12from work to care -25 to stay home for the child, and (2)151 the Southeast -27 -120 14 26 value of the parent’s lost productivity. Median WTP estimate to avoid one MRAD from Tolley et al. Northeast -19 -47 10 -20 (1986). Distribution is assumed to be triangular with a Northwest -23 -22 -19 -28 minimum of $22 and a maximum of $83, with a most likely Great Plains 23 -47 on assumption 142 value of $52-27 (2000$). Range is based that Southwest 44 -64 82 mild symptom 114 Minor Restricted value should exceed WTP for a single (the Activity Days $69 50 highest estimate for a single symptom—for eye irritation— Midwest 13 -26 162 (MRADs) is $16) and be less than that for a Work Loss Day. The Southeast -23 -100 5 26 triangular distribution acknowledges that the actual value Northeast -17 -42closer to the point estimate 5 is likely to be than either-14 extreme. 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