Supplemental Table 2. Results from the MASALA and MESA* Studies of a Multivariate Analysis of the Association between
Ethnicity and Ectopic Fat, Lean Mass and Adipokines [Sensitivity Analysis, adjusting for height]
South Asian
(n= 903)
White
(n=785)
Mean
(95% CI)
Chinese American
(n=251)
African American
(n=407)
Latino
(n=501)
Mean
(95% CI)
p-value
Mean
(95% CI)
p-value
Mean
(95% CI)
p-value
Mean
(95% CI)
p-value
253 (243-264)
257 (245-269)
268 (256-280)
0.002
< 0.001
< 0.001
177 (160-195)
201 (183-220)
211 (193-230)
< 0.001
0.05
0.13
298 (283-313)
291 (277-305)
301 (287-315)
< 0.001
< 0.001
< 0.001
264 (250-278)
273 (260-287)
278 (264-291)
< 0.001
< 0.001
< 0.001
159 (153-165)
157 (151-164)
166 (160-173)
< 0.001
0.10
0.001
114 (104-125)
114 (104-124)
124 (114-133)
< 0.001
< 0.001
< 0.001
128 (120-136)
126 (118-133)
137 (130-145)
0.08
< 0.001
0.004
164 (157-172)
160 (153-167)
164 (157-171)
< 0.001
0.06
0.02
28 (27-29)
25 (24-26)
26 (25-27)
< 0.001
0.01
0.07
19 (17-21)
17 (15-19)
18 (16-20)
< 0.001
< 0.001
< 0.001
21 (20-23)
19 (17-20)
20 (18-21)
0.99
< 0.001
< 0.001
26 (25-27)
25 (23-26)
25 (24-26)
< 0.001
0.02
0.03
85 (83-87)
88 (84-92)
92 (89-96)
< 0.001
< 0.001
< 0.001
74 (70-77)
74 (68-80)
79 (73-85)
< 0.001
0.46
0.07
67 (65-70)
65 (60-69)
69 (65-74)
< 0.001
0.05
0.39
88 (86-91)
85 (80-89)
87 (83-92)
< 0.001
< 0.001
< 0.001
61 (61-62)
61 (60-63)
59 (58-61)
< 0.001
< 0.001
< 0.001
62 (61-63)
64 (62-66)
61 (59-63)
< 0.001
< 0.001
< 0.001
63 (62-64)
66 (65-68)
64 (63-66)
< 0.001
< 0.001
< 0.001
59 (59-60)
61 (60-63)
60 (58-61)
< 0.001
< 0.001
< 0.001
98 (95-100)
101 (100-103)
< 0.001
< 0.001
89 (85-94)
101 (98-104)
0.04
< 0.001
104 (101-108)
109 (107-111)
< 0.001
< 0.001
99 (95-102)
105 (103-107)
< 0.001
< 0.001
24 (23-25)
23 (22-24)
23 (22-25)
< 0.001
< 0.001
< 0.001
17 (15-19)
16 (14-18)
15 (13-17)
< 0.001
0.06
0.90
18 (17-20)
17 (16-19)
17 (16-19)
< 0.001
< 0.001
0.007
20 (18-21)
19 (18-20)
20 (18-21)
< 0.001
< 0.001
< 0.001
16 (15-17)
15 (14-16)
< 0.001
< 0.001
15 (14-17)
14 (13-16)
< 0.001
< 0.001
18 (17-19)
17 (16-18)
< 0.001
< 0.001
16 (15-17)
15 (14-17)
< 0.001
< 0.001
Subcutaneous Fat Area (cm2)
Unadjusted
Model 1a
Model 2a
237 (227-246)
225 (211-240)
230 (215-244)
Visceral Fat Area (cm2)
Unadjusted
Model 1a
Model 2a
134 (129-140)
149 (141-157)
152 (144-159)
Total Muscle Fat Area (cm2)
Unadjusted
Model 1a
Model 2a
21 (20-22)
27 (25-28)
27 (26-29)
Pericardial Fat (cm3)#
Unadjusted
Model 1a
Model 2a
59 (55-62)
71 (66-75)
72 (67-76)
Hepatic attenuation (HU)#
Unadjusted
Model 1a
Model 2a
55 (54-56)
53 (51-54)
52 (51-54)
Total lean mass area (cm2)
Unadjusted
Model 1a
93 (91-96)
83 (80-85)
Adiponectin (ng/mL)
Unadjusted
Model 1a
Model 1b
12 (11-13)
14 (12-15)
15 (13-16)
Resistin (ng/mL)
Unadjusted
Model 1a
22 (21-23)
23 (22-24)
Model 1b
23 (21-24)
15 (14-16)
< 0.001
14 (13-16)
< 0.001
17 (16-19)
< 0.001
15 (14-16)
< 0.001
*Analyses for abdominal fat, intermuscular fat, lean mass, adiponectin and resistin performed using covariate data from Exams 2 and
3; analyses for pericardial fat and liver attenuation performed using covariate data from the baseline exam. N for each ethnic group in
MESA represents the number of participants from Exams 2 and 3.
For pericardial fat and hepatic attenuation analyses, N for MESA ethnic groups are as follows: White – 2622, Chinese American –
803, African American – 1893, and Latino – 1496.
#
Model 1a: Adjusts for age, sex, study site, alcohol, smoking history, exercise, education, household income, and height
Model 2a: Additionally adjusts for hypertension, diabetes, HDL and triglycerides
Model 1b: Additionally adjusts for subcutaneous fat area, visceral fat area, total intermuscular fat area, pericardial fat volume, and
hepatic attenuation