Cross reactivity
TCA
The table below lists compounds and their respective cutoff concentrations in urine that yield a
positive result (cross-react) with TCA (cutoff 1000).
Compound
Conc. (ng/ml)
Doxepin
2500
Clomipramine
2500
Protriptyline
5000
Amitriptyline
312
Despramine
156
Imipramine
156
BAR
The table below lists compounds and their respective cutoff concentrations in urine that yield a
positive result (cross-react) with BAR (cutoff 300).
Compound
Conc. (ng/ml)
Amobarbital
2500
Butabarbital
1250
Pentobarbital
1250
hexobarbital
N/A (negative in 200ug/ml)
MTD
Compound
Conc. (ng/ml)
Hydrocodone,
Hydramorphone
>20,000
Morphine-3-β-D-G
>20,000
Oxycodone
>20,000
Morphine
>20,000
Buprenorphine
>20,000
Cis-tramadol
>20,000
N-Desmethyl-Cis-tramadol
>20,000
O-Desmethyl-Cis-tramadol
>20,000
Norbuprenorphine
>20,000
Codein
>20,000
OXY
Compound
Conc. (ng/ml)
Hydramorphone
>20,000
Morphine-3-β-D-G,
Morphine
>20,000
Buprenorphine
>20,000
(±)Methadone
>20,000
Cis-tramadol
>20,000
N-Desmethyl-Cis-tramadol
>20,000
O-Desmethyl-Cis-tramadol
>20,000
Norbuprenorphine
>20,000
Codein
>20,000
Hydrocodone
313
BUP
Compound
Conc. (ng/ml)
Buprenorphine
10ng/ml
Hydramorphone
>20,000
Morphine-3-β-D-G,
Morphine
>20,000
Buprenorphine
>20,000
(±)Methadone
>20,000
Cis-tramadol
>20,000
N-Desmethyl-Cis-tramadol
>20,000
O-Desmethyl-Cis-tramadol
>20,000
Norbuprenorphine
15.6
Codein
>20,000
Hydrocodone
>20,000
The following compounds at the concentration 200ug/ml in urine can NOT yield a positive result
(cross-react) with BUP (cutoff 10).
Hydrocodone, Hydramorphone, Morphine-3-β-D-G, Morphine, (±)Methadone, Oxycodone,
Cis-tramadol, N-Desmethyl-Cis-tramadol, O-Desmethyl-Cis-tramadol
The following compounds at the concentration 20ug/ml in urine can NOT yield a positive result
(cross-react) with BUP (cutoff 10).
Codein
The Norbuprenorphine in urine at the concentration of 15.6ng/ml can yield a positive result
(cross-react) with BUP (cutoff 10).
OPI
Compound
Conc. (ng/ml)
Buprenorphine
10ng/ml
Hydramorphone
78
Morphine-3-β-D-G,
Morphine
78
Buprenorphine
>20,000
(±)Methadone
>20,000
Cis-tramadol
>20,000
N-Desmethyl-Cis-tramadol
>20,000
O-Desmethyl-Cis-tramadol
>20,000
Norbuprenorphine
15.6
Codein
>20,000
Hydrocodone
39
Oxycodone
39
The following compounds at the concentration 200ug/ml in urine can NOT yield a positive result
(cross-react) with OPI (cutoff 300).
(±)Methadone, Cis-tramadol, N-Desmethyl-Cis-tramadol, O-Desmethyl-Cis-tramadol,
Buprenorphine
The following compounds at the concentration 20ug/ml in urine can NOT yield a positive result
(cross-react) with OPI (cutoff 300).
Norbuprenorphine
The table below lists compounds and their respective cutoff concentrations in urine that yield a
positive result (cross-react) with OPI (cutoff 300).
Compound
Conc. (ng/ml)
Morphine-3-β-D-G
78
Hydrocodone
39
Hydramorphone
78
Oxycodone
39
Codein
15.6