Orcutt 1 Lexi Orcutt Prof. Domini English 250 Mediation Essay NSAIDs in the Racehorse Industry Non-steroidal anti-inflammatory drugs, or NSAIDs, are anti-inflammatory pain medications commonly used in the horse racing industry. When NSAIDs first came to the racing industry in the 1960’s, they seemed to be miracle drugs, reducing lameness and swelling along with providing comfort to the horses (Sykes). But the allowance of these drugs in the racing industry has become very controversial due to potential side effects they may cause the horses. Some of these side effects include further stress and injury to the horse, due to lack feeling, and an increase in the likeliness of gastro-intestinal ulcers. Because of these side affects, the majority of states have a threshold of five micrograms per milliliter of serum or plasma. NSAIDs contain beneficial factors in the health and comfort of racehorses, but the common overuse of these drugs can potentially harm these animals. With harsher punishment to the trainers and veterinarians administering these medications, hopefully the overuse of these drugs will decline, while still allowing their medical benefits in the racehorse industry. In support of NSAIDs it must be said that NSAIDs are the most common painrelievers in the world. People use these anti-inflammatory drugs, like aspirin and ibuprofen, on a regular basis to relieve discomfort and reduce fever and swelling. NSAIDs work by chemically blocking the effects of special enzymes - specifically cox- Orcutt 2 1 and cox-2. These enzymes play a key role in producing prostaglandins. Prostaglandins moderate contractions as well as inflammation. When the NSAIDs block the enzymes, the production of prostaglandins goes down, which in turn reduces pain and swelling. Prostaglandin also has other uses in the body, one of which includes protecting the lining of the stomach and the GI tract. When NSAIDs are over used and the prostaglandin levels are constantly low, the GI tract becomes irritated and damaged by normal gastric acid - causing gastro-intestinal problems (NSAIDs for Pain Relief). The most common NSAID used in the horse racing industry is phenylbutazone, or more commonly known as “bute”. Bute was first brought into the racing industry in 1960, 11 years after it became available to humans who commonly used it for gout and arthritis. But since Bute is such a stronger NSAID, it created a greater amount of complications and side effects in humans than aspirin or ibuprofen had. When Bute became legal in the racing industry, it was thought that it would increase the amount of starts a horse would have per year and decrease the amount of horse breakdowns. But when studies were conducted, the opposite seemed to be true. An informal study done at Keystone Park in Pennsylvania showed that before the legalization of bute, there was an average of one breakdown per fifteen days, and after bute was legalized there was average breakdown of one every four days. Also if you look back on the average number of starts for a horse per year in 1960 it was 11.31, it then dropped dramatically to 6.2 by 2008 (Sykes). With these statistics in mind, many people have advocated to making bute and other high-dosage NSAIDs illegal in horse racing. Dr. Scott Stanley a professor at Orcutt 3 UC Davis in an interview in 2008 stated that “for the past 20 years phenylbutazone (bute) has been the most common violation reported in the United States” (bloodhorse). Only about 1% of violations in the horse racing industry are due to illegal drugs (Q-Racing). The majority of infractions are due to the overuse of medication, like NSAIDs. Because of this overuse, many animal-rights activists claim that the only way to stop this misuse is to ban the drugs completely. The activist’s argument is that if a horse needs pain medication to compete in a race, the horse should not be racing at all. The horse should be taking time off to heal until it can race on its own. Horses that are overly medicated with NSAIDs are unable to feel the pain of their injury. Running at speeds up to 40 mph on an injured leg can cause further damage to the horse, such as stress fractures, that would end the horse’s career. Even if the horse is able to scathe through their short, 5-year long, career without a fatal injury, the over use of NSAIDs will leave their gastro-intestinal walls weaker and less immune to their body’s natural acid. The overuse of NSAIDs can have fatal repercussions and many people believe that the only way to stop this misuse is the ban these drugs all together. On the other side of the argument are the trainers, owners, and veterinarians that state NSAIDs are the same as common aspirin, and ibuprofen; and that the use of these drugs are strictly for the well-being and comfort of the horse. NSAIDs do provide great medical help to sore horses. They reduce swelling along with relieving any soreness caused from the horse’s workout. Racehorses are professional athletes with rigorous workout schedules to keep them in pristine racing shape; daily, hourlong workouts are bound to result in some soreness in the horse. Using NSAIDs in Orcutt 4 the racing industry is comparable to athletes taking aspirin before or after a game; it’s merely a form of pain relief from the physical stress of being a professional athlete. Trainers are using the technology and medication they have available to insure the greatest amount of comfort to the horses. The legal limit of five micrograms per milliliter of serum or plasma is low enough to ensure a very low percentage of side effects. And with this threshold upheld, trainers are able to provide comfort and decrease swelling for their horses without harming them. Advocates for the use of NSAIDs are correct in the fact that the threshold does provide comfort and safety of side affects to the horses however; that is not the issue with the drugs. The problem with NSAIDs in the racing industry is overuse. If the threshold could be upheld, horses would have a safe form of pain-killers. While I do believe that banning NSAIDs completely is an over-reaction, I propose national harsher punishment for trainers who repeatedly over use NSAIDS. In January of 2012, the Kentucky Horse Racing Commission (KHRC) applied stricter rules and harsher punishment for those administering illegal drugs, but refused to do the same for NSAIDs. “Strict penalties on the owner of any horse testing three times positive for levels of bute in excess of the allowable threshold within a time frame of 365 days” (tuesdayhorse) were proposed but shot down due to claimed disbelief of a horse testing positive three times within a year. Many suspect an ulterior motive; Kentucky, like many other states, does not want to be the first to enforce such penalties in the fear of losing business to other states (Allen). So along with stricter penalties, I propose a nation-wide regulation and set of penalties that all states would have to adhere to. Without all, or at least most, of the states agreeing to the Orcutt 5 same set of rules, regulatory rules in the racing industry will remain slack in the purpose of creating more revenue. For the safety of racehorses, along with providing them comfort, there should be a nation-wide legislation on stricter punishment for the overuse of NSAIDs. Orcutt 6 Work Cited Allen, Jane. "KHRC’s New Drug Regulations for Thoroughbreds Fail to Rein in the Bute." TUESDAYS HORSE. Int'l Fund for Horses, 25 Jan. 2012. Web. 09 Apr. 2013. "Arthritis Health Center." NSAIDs for Pain Relief. WebMD, n.d. Web. 09 Apr. 2013. "Fact Sheets." Horse Racing Fact Sheet. Int'l Fund for Horses, 2012. Web. 09 Apr. 2013. "Racing Medication Use." Q-Racing:. American Quarter Horse Association, 1 July 2012. Web. 09 Apr. 2013. Stanley, Scott, Dr. "Scott Stanley, Ph. D. UC Davis School of Veterinary Medicine." Horse Racing and Breeding Information from The Blood-Horse. Bloodhorse.com, 22 Aug. 2012. Web. 09 Apr. 2013. Sykes, Melissa. "The Story Behind Bute: History and Implications for Horse Health." All About Horses, Horse News, Horse Training, Horse Videos, and Blogs. Barnmice, n.d. Web. 09 Apr. 2013.