Supplementary Table S1: Patient Reactions
Group
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Allergic
Median
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Allergic, eats baked egg
Median
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to egg
Tolerant to peanut
Tolerant to peanut
Tolerant to peanut
Median
Control
Control
Control
Control
Control
Control
Age
(Y)
7.1
7.9
3.3
8.4
5.4
11
5.1
2.1
7.2
8.2
2.6
6.7
9.3
0.9
6.9
8.75
13.2
2.2
3.5
1.2
17.6
4.3
3.5
3.9
2.7
3.2
10
4.2
10.9
11.75
6.25
4.1
5.1
7.7
7.75
6.25
1.4
12.2
8.6
8.6
4.25
15.3
Initial reaction to egg at diagnosis
GI*
Anaphylaxis
Anaphylaxis
Skin
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Anaphylaxis*
Eating ad lib
Eating ad lib
Eating ad lib
Anaphylaxis
Skin*
Initial reaction to peanut at
diagnosis
Preventive avoidance
Skin*
Preventive avoidance
Preventive avoidance
Anaphylaxis
Anaphylaxis
Skin
Preventive avoidance
Preventive avoidance
Skin
Skin
Skin
Anaphylaxis
Eating ad lib
Skin
Skin
Skin
Skin
Skin
Skin
Preventive avoidance
Skin
Anaphylaxis
Anaphylaxis
Eating ad lib
Eating ad lib
Eating ad lib
Anaphylaxis
GI
Eating ad lib
Anaphylaxis
Skin
Skin
Anaphylaxis
Anaphylaxis
GI
Skin
Skin
Eating ad lib
Eating ad lib
Eating ad lib
Preventive avoidance
Skin*
Anaphylaxis
Preventive avoidance
Anaphylaxis
Skin
Eating ad lib
Eating ad lib
Skin
Anaphylaxis
Anaphylaxis
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Control
3.2
Eating ad lib
Control
10.5
Eating ad lib
Control
13.3
Eating ad lib
Control
7.9
Eating ad lib
Control
1.75
Eating ad lib
Control
8.9
Eating ad lib
Control
5.3
Eating ad lib
Control
8.75
Eating ad lib
Control
14.4
Eating ad lib
Control
13.2
Eating ad lib
Control
7.2
Eating ad lib
Control
14
Eating ad lib
Control
1.6
Eating ad lib
Control
1.4
Eating ad lib
Control
9.4
Eating ad lib
Control
14.4
Eating ad lib
Control
2.3
Eating ad lib
Control
8.3
Eating ad lib
Control
12.2
Eating ad lib
Median
8.6
Eating ad lib
*subsequently failed food challenge in clinic
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Eating ad lib
Supplementary Table S2: Tolerant Patient Characteristics
Group
Initial
Time Since Initial Reaction
sIgE at
sIgE at
Reaction
and Recruitment (Y)
Diagnosis
Challenge
Tolerant to egg
Anaphylaxis 1.8
N/A
.19
Tolerant to egg
Skin
2. 3
4.35
.78
Tolerant to egg
Skin
7.3
11.8
1.69
Tolerant to egg
Anaphylaxis 3.2
2.9
N/A
Tolerant to egg
Anaphylaxis 8.4
0.9
N/A
Tolerant to egg
GI
8
25.2
N/A
Tolerant to egg
Skin
5.3
N/A
N/A
Tolerant to egg
Skin
3
.36
.1
Tolerant to peanut Skin
4.1
N/A
.1
Tolerant to peanut Anaphylaxis 3.7
N/A
.13
Tolerant to peanut Anaphylaxis 2.25
1.41
.17
N/A = not available. sIgE not available at diagnosis means diagnosis was made by skin
prick test. If a patient passed an open challenge at home within 6 months of
recruitment,sIgE was not drawn.