NEGATIVE PREFIXES 1-2. A-/AnThese Greek-derived prefixes mark words expressing an absence of something (atypical, anodyne). A- is attached to words starting with consonants, and an- is the form for words beginning with vowels. An exception is words beginning with h; depending on the root word, either prefix may be present (ahistorical, anhydrous). 3. AntiAnti-, from Greek by way of Latin, means “opposite” (antithetical) or “in opposition to” (antivirus), and can also denote defense (antisubmarine) or prevention (antidepressant). 4. DisThis Latin prefix, when attached to a word, implies one of several meanings: absence (disaffected) or lack (disabled), opposition (disapprove), or removal (disenfranchise). 5. InIn- and its several variations, all signaling Latin derivation, also denote lack of a given quality. The variations il- and -ir are attached to words starting with l or r (illogical, irreversible). Im-, meanwhile, precedes m (immaterial) and p (impatient) and the lone example for b: imbalance. The rare prefix ig- sometimes comes before n (ignoble). In- appears before root words beginning with all other letters. 6. NonThis Latin negative prefix is the least particular of the class, and can often be found attached to root words so that the resulting term differs in meaning from one formed by the attachment of another negative prefix to the same root word. For example, nonrational means “not according to rational means or rules,” but unrational refers to behavior that does not conform to these norms. The nonparticular non- is the go-to negative prefix for neologisms. 7. UnBy contrast with the other negative prefixes, the attachment of this Latin-based form to a root word can, in addition to expressing lack or absence (unconcern), denote a reversal (uncoiled). It can also refer to an action not yet taken (unopened).