Paper ID Regular Paper B219 Sudeep Roy, Akhil Kumar, and Ivo Provazník, Virtual screening, ADMET profiling, molecular docking and dynamics approaches to search for potent selective natural molecule based inhibitors against metallothionein-III to study Alzheimer’s disease B223 Benjamin Y. S. Li, Lam Fat Yeung, and Genke Yang, Pathogen Host Interaction Prediction via Matrix Factorization B224 Trevor DeVore, Scott Winkleblack, Bruce Golden, and Chris Lupo, A Heterogeneous Compute Solution for Optimized Genomic Selection Analysis B244 Ilona Kifer, Rui M. Branca, Ping Xu, Janne Lehtio, and Zohar Yakhini, Optimizing analytical depth and cost efficiency of IEF-LC/MS proteomics B276 Yuan Ling, Yuan An, and Xiaohua Hu, A Symp-Med Matching Framework for Modeling and Mining Symptom and Medication Relationships from Clinical Notes B278 aiping qu, jiamei chen, linwei wang, jingping yuan, fang yang, qingming xiang, Ninu Maskey, guifang yang, Juan Liu, and yan li, Two-step segmentation of Hematoxylin-Eosin stained histopathological images for prognosis of breast cancer B286 Daniel Veltri, Uday Kamath, and Amarda Shehu, A Novel Method to Improve Recognition of Antimicrobial Peptides through Distal Sequence-based Features B287 Quazi Abidur Rahman, Larisa Tereshchenko, Matthew Kongkatong, Theodore Abraham, M. Roselle Abraham, and Hagit Shatkay, Identifying Hypertrophic Cardiomyopathy Patients by Classifying Individual Heartbeats from 12-lead ECG Signals B292 Xinran Yu, Turgay Korkmaz, Timothy Lilburn, Hong Cai, Jianying Gu, and Yufeng Wang, Heavy Path Mining Reveals Novel Protein-Protein Associations in the Malaria Parasite Plasmodium falciparum B306 Veronika Strnadova, Aydin Buluc, Jarrod Chapman, Joseph Gonzalez, Stefanie Jegelka, John Gilbert, Daniel Rokshar, and Leonid Oliker, Efficient and Accurate Clustering for Large-Scale Genetic Mapping B314 Zhexue Wei, Daming Zhu, and Lusheng Wang, A Dynamic Programming Algorithm For (1,2)-Exemplar Breakpoint Distance B323 Lishuang Li, Rui Guo, Zhenchao Jiang, and Degen Huang, Improving Kernel-Based Protein-Protein Interaction Extraction by Unsupervised Word Representation B328 Chang Sik Kim, Qing Wen, and Shu-Dong Zhang, Integrative analysis of chemo-transcriptomic profiles for drug-feature specific gene expression signatures B330 Haider Raza, Girijesh Prasad, Yuhua Li, and Hubert Cecotti, Covariate Shift-Adaptation Using a Transductive Learning Model for Handling Non-Stationarity in EEG based Brain-Computer Interfaces B331 Chun-Fu Wang, Kwan-Liu Ma, Chih-Wei Huang, and Yu-Chuan Li, A Visual Analysis Approach to Cohort Study of Electronic Patient Records B332 Wooyoung Kim and Sheil Kurmar, Efficient Updates of network motif instances in the extended proteinprotein interaction network B333 Mingjie Wang, Haixu Tang, and Yuzhen Ye, Identification and characterization of accessory genomes in bacterial species based on genome comparison and metagenomic recruitment B339 Fiona Browne, Haiying Wang, and Huiru Zheng, An Integrative Network-Driven Pipeline for the Prioritization of Alzheimer’s Disease Genes B342 Haiying Wang, Huiru Zheng, and Chaoyang Wang, Dynamics and Controllability in Cell Cycle Specific Protein Interaction Networks B344 Rudan Xu, Yuanyuan Sun, Zhihao Yang, Bo Song, Xiaohua Hu, and Xiaopeng Hu, Fractal Descriptor Applied to the Classification of HEp-2 Cell Patterns B350 En-Shiun Annie Lee, Ho-Yin Sze-To, Man-Hon Wong, Kwong-Sak Leung, Terrence Chi-Kong Lau, and Andrew K. C. Wong, Discovering Protein-DNA Binding Cores by Aligned Pattern Clustering B351 Xiaohua Hu and Minghong Fang, Prioritizing Disease-Causing Genes Based on Network Diffusion and Rank Concordance B352 CHRISTOPHER MA, YIXIN CHEN, and DAWN WILKINS, Ranking of Cancer Genes In Markov Chain Model Through Integration of Heterogeneous Sources of Data B353 Lin Zhu, Su-Ping Deng, and De-Shuang Huang, A Two-Stage Geometric Method for Detecting Unreliable Links in Protein-Protein Networks B355 Yongguo Mei, Adria Carbo, Raquel Hontecillas, Stefan Hoops, Nathan Liles, Pinyi Lu, Casandra Philipson, and Josep Bassaganya-Riera, ENISI MSM: A Novel Multi-Scale Modeling Platform for Computational Immunology B357 Qiang Yu, Hongwei Huo, Xiaoyang Chen, Haitao Guo, Jeffrey Scott Vitter, and Jun Huan, An Efficient Motif Finding Algorithm for Large DNA Data Sets B358 Osamu Maruyama and Shota Shikita, A scale-free structure prior for Bayesian inference of Gaussian Graphical models B365 Aidan Meade, Colin Clarke, Hugh Byrne, and Fiona Lyng, Selection of preprocessing methodology for multivariate regression of cellular FTIR and Raman spectra in radiobiological analyses B367 Didier Devaurs, Amarda Shehu, Thierry Siméon, and Juan Cortés, Sampling-based Methods for a Full Characterization of Energy Landscapes of Small Peptides B368 Inês V. Rodrigues, Pedro M. Ferreira, Ana R. Malheiro, Pedro Brites, Eduardo M. Pereira, and Hélder P. Oliveira, Morphometric Analysis of Sciatic Nerve Images: A Directional Gradient Approach B377 Chang Sik Kim, Seungwoo Hwang, and Shu-Dong Zhang, RMA with quantile normalization mixes biological signals between different sample groups in microarray data analysis B379 Başak Esin Köktürk and Bilge Karaçalı, Model-free Expectation Maximization for Divisive Hierarchical Clustering of Multicolor Flow Cytometry Data B382 Yun Su, Bin Hu, Lixin Xu, Hanshu Cai, Philip Moore, Xiaowei Zhang, and Jing Chen, EmotionO+: Physiological Signals Knowledge Representation and Emotion Reasoning Model for Mental Health Monitoring B384 Fengying Yu, Zhihao Yang, Yuanyuan Sun, Hongfei Lin, and Jian Wang, Data Integration and Supervised Learning Based Protein Complex Detection Method B386 Min-Seok Kwon, Yongkang Kim, Seungyeoun Lee, Junghyun Namkung, Taegyun Yun, Sung Gon Yi, Meejoo Kang, Sun Whe Kim, Jin-Young Jang, and Taesung Park, Multi-marker developement for pancreatic ductal adenocarcinoma using integrated analysis of mRNA and miRNA expression B390 Jian-Yu Shi, Siu-Ming Yiu, Yiming Li, Henry C. M. Leung, and Francis Y. L. Chin, Predicting Drug-Target Interaction for New Drugs Using Enhanced Similarity Measures and Super-Target Clustering B391 Matthias Becker and Nadia Magnenat-Thalmann, Muscle Tissue Labeling of Human Lower Extremities in Multi-Channel mDixon MR Imaging: Concepts and Applications B401 Qiao Wang, Fan Shi, Andrew Kowalczyk, Richard Campbell, Benjamin Goudey, David Rawlinson, Aaron Harwood, Herman Ferra, and Adam Kowalczyk, GWISFI: a Universal GPU Interface for Exhaustive Search of Pairwise Interactions in Case-Control GWAS in Minutes B402 Yan Yan, Anthony J. Kusalik, and Fang-Xiang Wu, NovoPair: de novo peptide sequencing for complementary spectra pair B413 Michael Andel, Jiri Klema, and Zdenek Krejcik, Network-Constrained Forest for Regularized Omics Data Classification B418 Xingpeng Jiang and Xiaohua Hu, Microbiome Data Integration by Robust Similarity Network Fusion B421 Alexander Schoell, Claus Braun, Markus Daub, Guido Schneider, and Hans-Joachim Wunderlich, Adaptive Parallel Simulation of a Two-Timescale Model for Apoptotic Receptor-Clustering on GPUs B422 Mehmet Tan, Drug sensitivity prediction for cancer cell lines based on pairwise kernels and miRNA profiles B423 Ana Stanescu and Doina Caragea, Ensemble-based semi-supervised learning approaches for imbalanced splice site datasets B433 Peiyan Zhu, Junhui Shen, Dezhi Sun, and Ke Xu, Mining Meaningful Topics from Massive Biomedical Literature B439 Mengwen Liu, Yuan Ling, Yuan An, Xiaohua Hu, Alan Yagoda, and Rick Misra, Relation Extraction from Biomedical Literature with Minimal Supervision and Grouping Strategy B440 Kimin Oh, Taeho Hwang, Kihoon Cha, and Gwan-Su Yi, Functional module-centric interpretation of transcriptomic change between human and chimpanzee cerebral cortex B444 Jing Zhao, Aron Henriksson, Lars Asker, and Henrik Boström, Detecting Adverse Drug Events with Multiple Representations of Clinical Measurements B448 Aron Henriksson, Hercules Dalianis, and Stewart Kowalski, Generating Features for Named Entity Recognition by Learning Prototypes in Semantic Space: The Case of De-Identifying Health Records B449 Yue Zhang, Kuanquan Wang, and Henggui Zhang, Simulation of Ventricular Automaticity Induced by Reducing Inward-rectifier K+ Current B456 Benjamin P Vandervalk, Shaun D Jackman, Anthony Raymond, Hamid Mohamadi, Chen Yang, Dean A Attali, Justin Chu, René L Warren, and Inanç Birol, Konnector: Connecting paired-end reads using a Bloom filter de Bruijn graph B461 Changlin Fu, Zhou Tan, Rui Liu, Shiying Hao, Zhen Li, Pei Chen, Taichang Jang, Milton Merchant, John Whitin, Oxford Wang, Minyi Guo, Harvey Cohen, Lawrence Recht, and Xuefeng Ling, CSF protein dynamic driver network: at the crossroads of brain tumorigenesis B464 David Rodriguez, Stephan Heuer, Alexandre Guerra, Wilhelm Stork, Benedikt Weber, and Markus Eichler, Towards automatic sensor-based triage for individual remote monitoring during mass casualty incidents B465 Ruimin Sun, Ye Tian, and Xin Chen, TAMeBS: a sensitive bisulfite-sequencing read mapping tool for DNA methylation analysis B470 Hongfei Cao, Michael Phinney, Devin Petersohn, Benjamin Merideth, and Chi-Ren Shyu, MRSMRS: Mining Repetitive Sequences in a MapReduce Setting B479 Haijun Gong and Lu Feng, Probabilistic Verification of ER Stress-induced Signaling Pathways Paper ID Short Paper B204 Pietro Hiram Guzzi, DMET-Miner: Efficient Learning of Association Rules from Genotyping Data for Personalized Medicine B218 Zehui He, Construct Validity of the Chinese version of WHOQOL-BREF & Disabilities Module in 1000 adults with disabilities: an Item Response Theory analysis B233 Zhaohui Liang, Jimmy Xiangji Huang, Gang Zhang, Honglai Zhang, and Jianhua Zhang, Deep Learning for Diagnosis and Healthcare Decision Making B237 Diyue Bu and Haixu Tang, Quasispecies Reconstruction Based on Vertex Coloring Algorithm B247 Caihua Wang, Juan Liu, Yafang Tan, Zixin Deng, and Qian-nan Hu, Pairwise Input Neural Network for LargeScale Target-Ligand Interaction Prediction B253 SeungHeui Ryu, NaHyun Kwak, and DoHoon Lee, VISWES: a system for finding related vaccinia virus protein sequences in cancer immune therapy B254 Yongnan Li, Arithmetic computation using self-assembly of DNA tiles: integer power over finite field GF(2n) B255 Bassam AlKindy, Christophe Guyeux, Jean-François Couchot, Michel Salomon, and Jacques M. Bahi, Gene Similarity-based Approaches for Determining Core-Genes of Chloroplasts B257 Daekeun You, Sameer Antani, Dina Demner-Fushman, and George Thoma, Biomedical Image Segmentation for Semantic Visual Feature Extraction B264 Diogo Pernes, Jaime S. Cardoso, and Hélder P. Oliveira, Fitting of Superquadrics for Breast Modelling by Geometric Distance Minimization B271 Hui-Hui Li, Feng-Feng Shao, and Guo-Zheng LI, Semi-supervised Imputation for Microarray Missing Value Estimation B279 Xiujuan Lei, Fei Wang, Fang-Xiang Wu, and Aidong Zhang, Detecting Functional Modules in Dynamic Protein-Protein Interaction Networks Using Markov Clustering and Firefly Algorithm B282 Guang Zheng, Exploring Potential Therapeutic Agents of Duhuo-Jisheng-Tang for Rheumatoid Arthritis B283 Pedro Costa, João P. Monteiro, Hooshiar Zolfagharnasab, and Hélder P. Oliveira, Tessellation-based Coarse Registration Method for 3D Reconstruction of the Female Torso B291 Jia-Ming Liu, Mingyu You, Zheng Wang, Guo-Zheng LI, Xianghuai Xu, and Zhongmin Qiu, Cough Detection Using Deep Neural Networks B297 Yuexu Jiang, Yan Wang, Wei Pang, Liang Chen, Huiyan Sun, Yanchun Liang, and Enrico Blanzieri, Essential Protein Identification based on Essential Protein-Protein Interaction Prediction by Integrated Edge Weights B302 Sultan Imangaliyev, Bart Keijser, Wim Crielaard, and Evgeni Tsivtsivadze , Personalized microbial network inference via coregularized spectral clustering B308 Athanasia Polychronopoulou and Zoran Obradovic, Hospital Pricing Estimation by Gaussian Conditional Random Fields Based Regression on Graphs B309 Shuo Xu, Guixin Wu, Dawei Tu, and Huiru Zheng, Human-Machine-Environment Cyber-Physical Systems and Hierarchical Task Planning to Support Independent Living B310 Subrata Saha and Sanguthevar Rajasekaran, Efficient algorithms for the compression of FASTQ files B324 Shuhua Chen, Juan Liu, and Tao Zeng, MMSE: a generalized coherence measure for identifying linear patterns B327 Xiao Wang, Guo-Zheng LI, Qiuwen Zhang, and De-Shuang Huang, MultiP-SChlo: multi-label protein subchloroplast localization prediction B335 Zhi-Peng Jiang, Fang-Fang Zhao, and Yi Guan, Developing a Linguistically Annotated Corpus of Chinese Electronic Medical Record B336 Sheehan Khan and Russell Greiner, Budgeted Transcript Discovery: A Framework For Joint Exploration And Validation Studies B337 Andreea Radulescu, Guillaume Fertin, Géraldine Jean, and Irena Rusu, DExTaR: Detection of Exact Tandem Repeats based on the de Bruijn graph B345 Qian Zhu, Hongfang Liu, Christopher chute, and Matthew ferber, Genetic Testing Knowledge Base (GTKB) towards Individualized Genetic Test Recommendation – An Experimental Study B346 Lishuang Li, Liuke Jin, Jieqiong Zheng, Panpan Zhang, and Degen Huang, The Protein-Protein Interaction Extraction Based on Full Texts B356 Xiaohua Hu and Junmin Zhao, A Novel Disease Gene Prediction Method Based on PPI Network B369 Lishuang Li, Zhenchao Jiang, and Degen Huang, An General Instance Representation Framework for Protein-Protein Interaction Extraction B373 Nancy Huang and Yen-Jen Oyang, Microbial Abundance Patterns of Host Obesity Inferred by the Structural Incorporation of Association Measures into Interpretable Classifiers B374 Nic Herndon, Karthik Tangirala, and Doina Caragea, Predicting Protein Localization Using a Domain Adaptation Naive Bayes Classifier with Burrows Wheeler Transform Features B380 Qinmin Hu, Liang He, Mingyao Li, and E. Mark Haccke, A Semi-informative Aware Approach using Topic Model for Medical Search B383 Sílvia Bessa, Inês Domingues, Jaime Cardoso, Pedro Passarinho, Pedro Cardoso, Vítor Rodrigues, and Fernando Lage, Normal breast identification in screening mammography: a study on 18 000 images B385 Xiaoxia liu, Zhihao Yang, Hongfei Lin, and Jian Wang, Exploring the relation between the characteristics of protein interaction networks and the performances of computational complex detection methods B387 Hong Song, Qian Zhang, and Shuliang Wang, Liver segmentation based on SKFCM and Improved GrowCut for CT images B394 xiaofang Wu, Zhihao Yang, Yuanyuan Sun, Hongfei Lin, and Jian Wang, Deep Graph Search Based Disease Related Knowledge Summarization From Biomedical Literature B395 Yongkang Kim and Taesung Park, Identifying differentially expressed genes for ordinal phenotypes B396 Darren O'Doherty, Yogesh Kumar Meena, Haider Raza, Hubert Cecotti, and Girijesh Prasad, Exploring Gaze-Motor Imagery Hybrid Brain-Computer Interface design B398 Nicolas Maillet, Guillaume Collet, Thomas Vannier, Dominique Lavenier, and Pierre Peterlongo, COMMET: comparing and combining multiple metagenomic datasets B408 Bolin chen, Min Li, Jianxin Wang, and Fang-Xiang Wu, A logistic regression based algorithm for identifying human disease genes B409 Jungrim Kim, Jeagyoon Ahn, Youngmi Yoon, Yunku Yeu, and Sanghyun Park, Discovering phenotype specific gene module using a novel biclustering algorithm in colorectal cancer B415 Yizhou Zang, Yuan An, and Xiaohua Hu, Automatically Recommending Healthy Living Programs to Patients with Chronic Diseases through Hybrid Content-Based and Collaborative Filtering B420 Keith Feldman and Nitesh Chawla, Admission Duration Model for Infant Treatment (ADMIT) B429 Jiangwen Sun, Jinbo Bi, and Henry Kranzler, Identifying Heritable Composite Traits from Multivariate Phenotypes with Genome-Wide SNPs B432 Yang Bai, Shufan Ji, and Yadong Wang, ESclassifier: a random forest classifier for detection of exon skipping events from RNA-Seq data B437 Amrisha Bhosle and Nagasuma Chandra, Different cancer cell lines resistant to the same drug exhibit differences in folate pathway dynamics B445 Robert Schuler, Carl Kesselman, and Karl Czajkowski, Digital Asset Management For Heterogeneous Biomedical Data in an Era of Data-Intensive Science B454 Kaidi Ma, Marco Canepa, James Strait, and Hagit Shatkay, Using Unsupervised Learning to Determine Risk Level for Left Ventricular Diastolic Dysfunction B462 Moumita Bhattacharya, Deborah Ehrenthal, and Hagit Shatkay, Identifying Growth-Patterns in Children by Applying Cluster analysis to Electronic Medical Records B463 Fan Yang and George Karypis, Signaling Adverse Drug Reactions with Novel Feature-based Similarity Model B469 Yiming Zuo, Guoqiang YU, Chi Zhang, and Habtom Ressom, A new approach to investigate the inter and intra relationships for multi-omics data integration B473 Quangang Zheng, Haidong Lan, and Weiguo Liu, XPFS: A New Parallel PROSITE Profile Search Algorithm on Xeon Phi B476 Xi Wen, Hong Wang, and Weiming Zhai, Automatic and Fast Registration Method for Image-Guided Surgery B477 Alexandru Mizeranschi, Huiru Zheng, Paul Thompson, and Werner Dubitzky, A multi-model reverseengineering algorithm for large gene regulation networks B478 Tomasz Oliwa and Yang Shen, A framework of complex-based normal mode analysis (cNMA) to model conformational changes of proteins upon interactions B480 Mahua Bhattacharya, Koushik Pal, and Goutam Ghosh, GUI based Smart Breast Cancer Identification System Using 2nd Level Secured Combined Crypto-Watermarking