CANINE EPILEPTOID CRAMPING SYDNROME IN BORDER TERRIERS Border terriers are known to suffer from a condition called Canine Epileptoid Cramping Syndrome (or Spike’s disease). Border terriers with CECS have episodes of difficulty walking, ranging from incoordination to a complete inability to stand, and flexing of the limbs, head and neck. Episodes can last minutes or hours with dogs being normal in between. Some owners have reported mild to severe gastrointestinal signs such as vomiting or diarrhoea in between episodes, though this is not always seen. Importantly, dogs usually remain aware of their surroundings during an episode and will recognise their name being called. This and often the long duration of the episodes distinguishes CECS from an epileptic seizure. An epileptic seizure (or fit) is a sudden and uncontrolled burst of electrical activity in the brain that may cause your dog to chomp and chew, foam at the mouth, jerk the legs, and involuntarily pass urine or stools. Dogs are usually unresponsive during a seizure and gradually regain normal awareness minutes or hours after the fit. Recently, we have identified blood markers (biomarkers) that support the hypothesis that CECS in Border terriers is linked to a specific type of diet. We are now seeking Border terriers with suspected CECS as well as Border terriers with epileptic seizures in order to further develop this diagnostic blood test. In doing this it is hoped we can understand the cause of CECS and see if we can find better ways of treating the condition. The aim is to use this information to help affected Border terriers and their owners who were left until now with no means of diagnosing or treating this debilitating condition. It is hoped that this research may even become useful to help people who suffer from similar conditions. If you think your Border terrier may have epileptic seizures or CECS, or something that may resemble one of these conditions, or if you would like further information, then please contact Mark Lowrie at the address below, email: mll@vetspecialists.co.uk or telephone +441582 883950. We add our reassurance that all details collected from owners and their dogs will be anonymised by the principal veterinary investigator (ML) and all identification data will remain strictly confidential. Mark Lowrie, Laurent Garosi, Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion, Hertfordshire SG5 3HR, United Kingdom.