ADHD Medication Chart From Web MD Class Drug Name Form Amphetamine Stimulants Adderall Short-acting Dexedrine Short-acting Dextrostat Short-acting Dexedrine Spansule Long-acting Adderall XR Long-acting Vyvanse Long-acting (prodrug) Methylphenidate Stimulants Focalin Short-acting Methylin Short-acting Ritalin Short-acting Metadate ER Intermediateacting Methylin ER Intermediateacting Ritalin SR Intermediateacting Metadate CD Intermediateacting Ritalin LA Intermediateacting Concerta Long-acting Nonstimulants Quillivant XR Long-acting Focalin XR Long-acting Daytrana patch Long-acting Strattera Long-acting (atomoxetine) (extended release) Duration Common Side Effects 4-6 Some loss of hours appetite, weight loss, sleep problems, 4-6 hours irritability, tics. Shortacting medicines 4-6 require frequent hours dosing. 6-8 Some loss of hours appetite, weight loss, 8-12 sleep problems, hours irritability, tics. Longacting medicines are 10-12 convenient but may hours have greater effects on appetite and sleep. 4-6 Some loss of hours appetite, weight loss, sleep problems, 3-4 hours irritability, tics. Shortacting medicines 3-4 require frequent hours dosing. 6-8 Some loss of hours appetite, weight loss, sleep problems, 6-8 hours irritability, tics. Longer-acting 4-8 medicines are hours convenient but may 8-10 have greater effects hours on appetite and 8-10 sleep. hours 10-12 Some loss of hours appetite, weight loss, 8-12 sleep problems, hours irritability, tics. Longer-acting medicines are convenient but may have greater side effects on appetite and sleep. 6-10 hours 10-12 Skin irritation, some hour loss of appetite, weight loss, sleep problems, irritability, tics. 24 hours Sleep problems, anxiety, fatigue, upset stomach, dizziness, dry mouth. Rarely, liver damage. There are some concerns about a link between Strattera and suicidal thoughts. Long-acting 24 hours Sleepiness, Intuniv (extended headache, fatigue, (guanrelease) abdominal pain. facine) Rarely, Intuniv can cause low blood pressure and heart rhythm changes. Antidepressants Wellbutrin Short-acting 4-5 Sleep problems, hours headaches. Although Wellbutrin Sustained 12 hours rare, Wellbutrin may increase the risk of SR release seizures. (long-acting) Wellbutrin Extended 24 hours XL release (long-acting) Tofranil NA 8-24 Sleep problems, hours anxiety, fatigue, Pamelor NA 8-24 upset stomach, hours dizziness, dry mouth, elevated heart rate, Aventyl NA 8-24 risk of heart hours arrhythmias. Norpramin NA 8-24 Not recommended for hours children. Associated with cases of fatal heart problems. Blood NA Fatigue, dizziness, Clonidine 4-6 Pressure hours dry mouth, irritability, Medicines (tablets) behavior problems, low blood pressure. Catapres or 24 hours Stopping this (patch) medicine suddenly can result in high 24 Kapvay blood pressure. hours (Tablet taken twice a day) Tenex NA 6-8 (guanhours facine) ADHD Medicines and Safety The FDA has issued a warning about the risk of drug abuse with amphetamine stimulants. FDA safety advisors are also concerned about the possibility that all amphetamine and methylphenidate stimulants used for ADHD may increase the risk of heart and psychiatric problems. The FDA has also issued a warning about a connection between antidepressants (including the non-stimulant Strattera) and an increased risk of suicide in adults aged 18-24, especially in the first one or two months of treatment. While these risks may seem alarming, keep in mind that experts generally consider these medicines safe. Serious problems are rare. Still, you should discuss the risks and benefits of these drugs with your doctor.