Jefferson Summer Research Program: Potential Projects February 20, 2015 DERMATOLOGY Students interested in research with the Department of Dermatology should contact the Jefferson Dermatology Society (Jordan.Wang@jefferson.edu). GENETICS Principal Investigator Douglas Hooper Contact Douglas.Hooper@jefferson.edu Project Title Immunomodulation in cancer; understanding the genesis and function in the brain of immunomodulatory M2 monocytes that infiltrate malignant astrocytomas Checkpoint inhibitors in lung cancer (collaboration with Dr. Bo Lu) *Projects are built around students’ individual interests* OBGYN Principal Investigator Jason Baxter Vincenzo Berghella Contact Project Title Jason.Baxter@jefferson.edu Gynecologic Transvaginal Ultrasound Training for OB/GYN Residents Current practice of blood volume approximation and utility of an educational training session on blood loss estimation for Labor and Delivery staff Vincenzo.Berghella@jefferson.edu Recent Changes in the Incidence of Cervical Cerclage Acceptance of Universal Cervical Length Screening in Women with Prior Preterm Birth Pregnancy Health Interview Study (NIH-NICHD AHRQ Administered by Boston University) Prevention of Preterm Birth with a Pessary in Twin Gestations (PoPPT) Prevention of Preterm Birth with Pessary Study (PoPPS) Prematurity Database Pre-pregnancy BMI and cerclage success Rupsa Boelig Rupsa.Boelig@jefferson.edu Universal cervical length screening for preterm birth prevention and its impact on pregnancy outcomes Amy Braverman Amy.Braverman@jefferson.edu Single Fathers by Choice? An exploration of the route to parenthood for single men who become fathers via surrogacy Does AIDET Training Change Residents' Values About Patient Care Positive and Negative Professional Behavior: Perceptions from a Third Year OB/GYN Experience Theresa BurcherAbigail Wolf Abigail.Wolf@jefferson.edu Obstetric Provider Effectiveness in Increasing Breastfeeding Intentions Gregory Fossum Gregory.Fossum@jefferson.edu Sigmoid colon adhesions and their effect on IBS Alexis Gimovsky Alexis.Gimovsky@jefferson.edu Maternal physical activity in women with PPROM Outcomes of exposed fetal membranes from 15-24 weeks Tei index during labor A randomized, controlled trial of usual labor vs extended second stage of labor Teaching patients about Operative Delivery Meiling Hua Meiling.Hua@jefferson.edu Is treatment for chorioamnionitis with ampicillin/sulbactam(unasyn) a risk factor for developing neonatal enterocolitis? Medical Comorbidities and their Impact on Pregnancy Outcomes Rebecca JacksonJacqueline Amis Rebecca.Jackson@jeffesron.edu Jacqueline.Amis@jeffesron.edu Predicting Hemoglobin after a Planned Cesarean Section - A multivariable Approach Caleb Kallen Caleb.Kallen@jefferson.edu Matthew ManfrediniLowery Matthew.ManfrediniLowery@jefferson.edu Rebecca Mercier Rebecca.Mercier@jefferson.edu Expression and function of ZFP36 in human corpus luteal cells Diabetes in pregnancy: association of glycemic control and perinatal outcomes A gynecological curriculum for residents in a community hospital setting Pregnancy Planner: Provider Perception and Usage of Patient-Held Prenatal Healthe Records Prediction of HPV Vaccination uptake rates in women attending an urban family planning clinic Use of peanut ball to decrease duration of active labor in laboring patient Randomized Control Trial of Peanut ball and Active Labor in Nulliparous 30-cc vs. 60-cc Foley Balloon in Induction of Labor Pregnancy Centering in the Privately Insured Population Joseph MontellaAlexander Berger Joseph.Montella@jefferson.edu Alexander.Berger@jefferson.edu Complications in Obese Patients Undergoing Retropubic Tension-free Vaginal Tape Surgery for Stress Incontinence Amanda RomanCamargo Amanda.RomanCamargo@jefferson.edu Perinatal outcome of Twin Pregnancies Complicated by Cervical Insufficiency Before 24 wks Gestation Corina Schoen Corina.Schoen@jefferson.edu Maternal and Perinatal Outcomes in Pregnancy Complicated with Hypertensive Disorders Zolpidem for the management of symptomatic early labor Foley with oxytocin versus Foley no oxytocin for induction of labor (NOFOX): a randomized control trial Anju Suhag Anju.Suhag@jefferson.edu Stuart Weiner Stuart.Weiner@jefferson.edu Does the Fetus with Klinefelter Syndrome have didproportionately long femur bones Cardiovascular Ultrasound Measurements in the Human Fetus Database Caffeine and fetal arrhythmia; could there be a causitive link? Decision Making in Prenatal Testing NIPDT Registry- A Multicenter clinical data collection of non-invasive prenatal diagnosis test recently introduced to clinical practice Abigail WolfCatherine Ford Abigail.Wolf@jefferson.edu Catherine.Ford@jefferson.edu JeffHOPE Preceptor Experiences and Influences on Resident Education Fetal TEI index and diabetes in pregnancy Ultrasound indicated cerclage and subsequent pregnancy outcomes based on type of cerclage OTOLARYNGOLOGY Principal Investigator Beth Duddy Contact Elizabeth.Duddy@jefferson.edu Joseph Curry Joseph.Curry@jefferson.edu Adam Luginbuhl Adam.Luginbuhl@jefferson.edu Project Title Beth Duddy is the clinical research nurse for the department Tumor metabolism; translational projects involving xenografting tumor cell lines into mice, collection clinical data, immunohistochemical analysis of tumor specimens *Students need to be integrated into the project prior to the start of the summer* Head and neck cancer MEDICINE Principal Investigator Raymond Penn Contact Project Title Raymond.Penn@jefferson.edu Dr. Penn runs the Center for Translational Research at Jefferson. The Penn lab studies GPCRs and their role in airway biology. Tung Chan Tung.Chan@jefferson.edu The Chan lab investigates the roles of PI3K/Akt survival signals and adenosine G-protein-coupled receptors in heart failure development Paul Bray Paul.Bray@jefferson.edu Dr. Bray is the director of the Cardeza Foundation for Hematologic Research at Jefferson and the director of Hematology. The Bray laboratory studies the role of platelets in cardiovascular disease and disorders of bleeding and excessive blood clotting. David Whellan David.Whellan@jefferson.edu Dr. Whellan runs the Clinical Research Program in the Department of Medicine. PATHOLOGY Principal Investigator Gyorgy Hajnoczky Contact Project Title Gyorgy.Hajnoczky@jefferson.edu Evaluate mitochondrial Ca2+ transport in MICU1deficient MEFs and primary cells using fluorescence microscopy techniques; MICU1 drug targets Isidore Rigoutsos Isidore.Rigoutsos@jefferson.edu Analyze the nuclear sequences of metazoan genomes to identify lookalikes of mitochondrial tRNAs; investigate which of these lookalikes show evidence of transcription Familiarity of Linux, OSC, Cygwin, or UNIX is required. Amity Roberts Amity.Roberts@jefferson.edu Renu Bajaj Renu.Bajaj@jefferson.edu Validation of FISH (fluorescence in-situ hybridization) probes Erin Seifert Erin.Seifert@jefferson.edu Investigating the role of mitochondrial thioesterase loss in cardiac dysfunction in female mice, in particular, increased permeability transition pore opening Comparing different commercial antimicrobial susceptibility panels for consistency (as part of a clinical trial) Proof-of-concept study, comparing current practice identification and antimicrobial susceptibility testing to a single platform Guiyun Zhang Guiyun.Zhang@jefferson.edu Seeking teaching assistants for the physician assistant anatomy course over the summer UROLOGY Principal Investigator Contact Costas Lallas Costas.Lallas@jefferson.edu Project Title Evaluation of combined TRUS (trans-rectal ultrasound)/MRI fusion prostate biopsy in prostate cancer diagnosis