Philippine General Hospital University of the Philippines, Manila Department of Pediatrics Section of Pediatric Hematology-Oncology Daily Census As of November 30, 2009 Fajardo/ Coniconde/ Serna B16 B17 B18 B19 B20 B26 SERVICE BEDS 5 SIANQUITO AVILA DIZON MARIBOJO SANDINO CAPARAS PER CN 2713691 DOA 11/29/09 DOB 4/27/00 W 11 3 B3 AYO B12 JIMENEZ B33 ROSALES PER 3 RIQUE RIQUE, Marvin 9/ M Wt 26.7 PER MARIBOJO PIMENTEL SALUNA MALAYON MARIBOJO PINILI (11/22) Patient with recurrent epistaxis On day of consult, patient had epistaxis Qualitative PLatelet Defect SERVICE BEDS W9 B16 CN 3490264 DOA 11/5/09 DOB 11/3/93 SIANQUITA, Carolyn 16/ F Wt. 41 kg Ht 160 BSA. 1.35m2 Spinal Cord Compression secondary to Spindle Cell Tumor Urinary tract infection secondary to Neurogenic Bladder R/O Metastasis 1 month PTA- abdominal mass on LQ of abdomen, consulted private MD, CT Scan: complex left abdominopelvic mass with infiltration neural foramina and spinal canal, osteolysis of the transverse prcess and infiltration of the L iliacus and iliopsoas muscle. Consideration: neurofibrosarcoma. + retroperitoneal lymphadenopathy 15 day PTA- px seen at CI OPD; repeat work up was requested. BMA done: mildly to moderately hypocellular marrow with trilineage hematopoeisis, no evidence of tumor involvement 3 days PTA- fever, (+) difficult in urination, vomiting, fecal incontinence 1 day PTA- in severe pain DISCHARGED WARD CALIMPONG ESGUERRA BEDS SUAREZ HERNANDEZ VALENCIA (11/22) MORTALITY 1 RAMOS (REFERRAL) (9/18?) SIGNED OUT Villapando Abadines TOS Maligaya AB+ CBC (11/29) 108/ 0.326/ 0.538/ 0.301/ 0.066/ 0.092/ 0.003/ 146 URINALYSIS (11/19) yellow/ clear/ SG 1.025/ pH 6.5/ CHO (-)/ CHON (-)/ rbc 0-1/ wbc 0-1/ ec (-)/ bact few/ mt occ/ ca oxalate few For BT of PC 5u q8 B+ CBC (11/13) 106/ 0.289/ 13.3/ 0.771/ 0.151/ 0.062/ 0.016/ 574 (11/5) 102/ 0.304/ 25.17/ 0.847/ 0.072/ 0.077/ 0.003/ 0.001/ 257 MCV 85.9/ MCH 28.8/ MCHC 336/ RDW 13.8 Normocytic, normochromic, no toxic granulations seen PT/ PTT (11/5) 13.1/ 15.7/ 0.65/ 1.5 36.4/ 54.9 BLOOD CHEM (11/25) BUN 4.28/ crea 41/ Na 137/ K 3.7/ Cl 101 (11/5) Gluc 5.93/ BUN 2.9/ crea 46/ UA 0.14/ alb 24/ TB 1.3/ DB 0.76/ IB 0.55/ alk phos 272/ AST 84/ ALT 24/ Ca 1.99/ Mg 0.96/ Phos 0.79 LDH 1362/ Na 134/ K 3.8/ Cl 97 24 HOUR URINE COLLECTION (11/9) TV 660/ TP 0.132/ TC 0.730 URINALYSIS (11/23) yellow/ hazy/ SG 1.01/ pH 8.5/ CHO (-)/ CHON 2+/ rbc 4-6/ wbc 80-90/ ec (-)/ bact 4+/ mt (-) (11/23) yellow/ turbid/ SG 1.01/ pH 8.5/ CHO (-)/ CHON 2+/ rbc 70-80/ wbc 80-90/ eco cc/ bact 3+/ mt rare/ triple phos few (11/21) yellow/ turbid/ SG 1.005/ pH 8.5/ CHO (-)/ CHON 1+/ rbc 0-2/ wbc 10-15/ ec (-)/ bact 3+/ mt (-)/ triple phosphate 3+/ (11/5) dark yellow/ sl hazy/ SG 1.020/ pH 7.5/ (-) sugar/ 1+ CHON/ 3-7 RBC/ 2-5 WBC/ 0-1 hyaline cast/ few ec/ occ bac/ (-) MT BLOOD CS (11/10) NG5D BMA (11/2) Mildly to moderately hypocellular marrow with trilineage hematopoeisis; no evidence of involvement by a tumor CORE NEEDLE BIOPSY (11/13) fragments of skeletal muscle, fibrocollagenous tissue ans scanty For MRI of the spine For bone scan For Lumbosacral APL xray For DMSA For Urine GS/CS T/S Tranexamic Acid Cefuroxime Morphine SO4 Gabapentine Paracetamol Lactulose T/S Nitrofurantoin Cpntinue bedside rehab For chemptherapy using rhabdomyosarcoma protocol once with meds W9 B17 CN DOA 11/6/09 DOB 7/15/95 W9 B18 CN 3171048 DOA 11/4/09 DOB 4/25/04 AVILA, Patricia 14/ F Wt: 40 kgs Myelodysplastic Syndrome R/O AML conversion CAP, resolved R/O Fungal Sepsis DIZON, Gabrielle Ryaine 5/ F 17 kg 110.5 cm BSA 0.72 Ganglioneuroblastoma, posterior mediastinum Stage IV with Tumor recurrence S/P Induction Chemotherapy (OPEC, OJEC Protocol, 2009) CAP, resolved P. putida sepsis, resolved SVC/SMS ruled out Patient is a diagnosed case of MDS since April 2008 by BMA biopsy initially presenting with easy fatigability; onregular ffup c/o HO. Patient was apparently well until 1 day PTA, patient had sudden onset of generalized pallor associated with undocumented fever and colds. Persistence prompted consult and subsequent admission. Diagnosed case of ganglioneuroblastoma, posterior mediastinum, stage II b by excision biopsy at St. Lukes Hospital 6/14/09, initially presenting with nonproductive cough and an incidental finding of mass in CXR; no fever, no weight loss. Patient completed induction chemotherapy with OPEc-OJEC protocol (Vincristine, Cisplatin, Etoposide-Vincristine, Cyclophosphamide,Etoposide, Carboplatin) from September 2007-January 2008. However, reinduction chemotherapy is contemplated with ICE protocol (ifos, carboplatin, etoposise) for tumor recurrence which started 3PTA as a mass on the lateral anterior neck. Last CT Scan of the chest revealed cervicothoracis paravertebral mass: tumor progression. Patient was apparently well until 5 days PTA- nonproductive cough, no fever, good appetite; consult done at OPD; given with Cefuroxime without relief 2 days PTA- (+) weakness in standing up (walang pwersa); no consult done 1 day PTA- (+)fever on and off Tmax 39.1 PER spindle cell tumor KUB UTZ (11/26) normal UTZ O+ CBC (11/28) 47/ 0.146/ 6.9/ 0.786/ 0.146/ 0.058/ 0.007/ 0.003/ 8 (11/23) 73/ 0.231/ 6.93/ 0.69/ 0.18/ 0.05/ 0.01/ stab 0.02/ meta 0.02/ myelo 0.01/ reactive lym 0.03/ plt 209 (11/18) 42/ 0.135/ 5.78/ 0.69/ 0.09/ 0.19/ 0.02/ stab 0.01/ nrbc 30/ 11 (11/14) 55/ 0.193/ 3.34/ 0.515/ 0.332/ 0.114/ 0.033/ 16/ normocytic/ hypochromic/ no TG (11/9) 75/ 0.237/ 21.4/ 0.52/ 0.27/ 0.02/ 0.03/ 0.01/ 15/ stab 13/ meta 01/ promyelo 01/ NRBC 85/100/ plt 15 (11/6) 48/ 0.156/ 19.66/ 0.36/ 0.536/ 0.066/ 0.007/ 0.031/ 12 BLOOD CHEM (11/18) Ca 1.84/ Na 139/ K 2.8/ Cl 102 (11/12) Ca 1.97/ Na 133/ K 6.6/ Cl 104 (11/11) ca 2.02/ na 134/ k 4.7/ cl 102 (11/10) ca 1.97/ na 133/ k 6.6/ cl 104 (11/8) ca 1.84/ na 139/ k 2.8/ cl 102 (11/7) BUN 16.4/ crea 132/ Ca 1.89/ Na 133/ K 3/ Cl 96 URINALYSIS (11/21) amber/ clear/ SG 1.015/ pH 7.5/ CHO (-)/ CHON 2+/ rbc 35-45/ wbc 2-6/ hyphal elements (-)/ eco cc/ bact few/ mt (-)/ coarse gran cast 2-3/ hgb 37 (11/9) dark yellow/ hazy/ SG 1.01/ pH 7.5/ CHO (-)/ CHON 2+/ RBC 3-8/ WBC 0-2/ eco cc/ bact 1+/ mt rare BLOOD CS (11/23) NG5D (11/7) NG5D CXR CAP A+ CBC (11/20) 87/ 0.311/ 9.83/ 0.767/ 0.111/ 0.121/ 0.000/ 0.001/ 227 (11/12) 92/ 0.309/ 10.11/ 0.727/ 0.139/ 0.131/ 0.002/ 0.001/ 544 (11/8) 102/ 0.338/ 12.19/ 0.751/ 0.108/ 0.133/ 0.006/ 742 (11/2) 110/ 0.346/ 13.64/ 0.736/ 0.136/ 0.127/ 0.0/ 0.001/ plt 341 ABG (11/29) 7.443/ 33.9/ 70/ 23.2/ 0.1/ 94.7 (11/17) 7.433/ 55.6/ 102.9/ 32.5/ 9.9/ __ (11/16) 7.418/ 51.3/ 114.1/ 29.9/ 6.8/ 98.5 (11/15) 7.466/ 46.8/ 159.7/ 31/ 8/ __ (11/12) 7.478/ 42.5/ 84.8/ 26.9/ 2.1/ 96.5 (11/11) 7.41/ 42.5/ 84.8/ 26.9/ 2.1/ 96.5 (11/5) 7.474/ 33.2/ 118.9/ 24.8/ 0.5/ 98.9 BLOOD CHEM (11/16) ca 2.22/ na 135/ k 4.2/ cl 92 (11/14) bun 1.46/ crea 31/ alb 28/ ca 2.22/ na 137/ k 3.2/ cl 90 (11/12) RBS 3.95/ crea 25/ ua 0.42/ AST 84/ ALT 38/ Ca 2.24/ Mg 0.96/ LDH 855/ Na 135/ K 4.2/ Cl 94 (11/12) plasma K 3.6 (11/2) Gluc 6.29/ BUN 2.89/ crea 42/ UA 0.23/ alb 27/ TB 0.39/ DB 0.08/ IB 0.31/ alk phos 162/ AST 81/ ALT 26/ Ca 2.3 / Mg 0.96/ Phos 1.33 LDH 761/ Na 133/ K 4.4/ Cl 96 PT/PTT (11/17) 15.2/ 13.4/ 0.8/ 1.15 For Post-BT CBC with PBS after 3u PRBC For U/A with RBC morphology For Fecalysis with OB For cytogenetics C/O NIH Fluconazole (6) D/C Paracetamol prn Diphenhydramine prn IVF: D5 0.3 NaCl (50% FM) DAT For BT of pRBC x 2 more doses For BT of PC q8 S/p 1u pRBC and 5u PC since last CBC For ABG Repeat CBC PT/PTT Neck STAPL Paracetamol Glycerine Suppository Dexamethasone 4mg IV q6 Feeding 100cc/ NGT q4 IVF D5 0.3 NaCl (FM) ET 4.5 L 15 40% TV 170(10) RR 30 PEEP 5 Referred to Hospice For possible tracheostomy W9 B19 CN 2862560 DOA 11/25/09 DOB 10/18/04 W9 B20 CN 3494213 DOA 10/30/09 DOB 10/3/01 MARIBOJO, Jay Ar 5/ M Wt 14.2 kg Beta-Thalassemia CAP R/O Sepsis In High Output Failure probably secondary to Anemia SANDINO, Lyra 8/ F Wt 16.2 kg Ht 112 cm AML Patient is a diagnosed case of B-Thalassemia c/o PGH since 2005, presenting qwith pallor and abdominal enlargement. 4 days PTC, (7 days post discharge), patient developed cough, productive of yellowish sputum associated with fever, weakenss and difficulty in breathing. Persistence prompted consult and subsequent admission 3 mos PTA, (+) non-productive cough with no other associated ssx; no consult done 2 mos PTA, (+) left eye swelling; consulted an ophthalmologist who prescribed antibiotics with no relief of symptoms 1 mo PTA, upon ff-up, px advised orbital CT scan; due to increase in swelling px consulted pgh ophtha hence admitted; referred to H-O for co-mgt. A> T/C AML based on CBC results. BMA done; transferred to H-O bed for further management. (11/12) 36/ 31.2 (11/2) 11.1/14.5/0.73/1.39 31.3/46.2 URINALYSIS (11/3) Lt yellow/ clear/ 1.025/ 6.0/ -gluc/ -P/ 0-1 RBC/ 3-6 WBC/ few bact/ occ ec/ occ mt BLOOD CS (11/12) NG2D – NG5D (11/3) NG2D – (+) Psudomonas putida S: Ciprofloxacin 2D ECHO (11/5) large cystic mass obscuring the aortic arch and slightly compressing the left side of the heart; mild TR, mild MR; EF 82%, FS 49.3% A+ CBC (11/28) 100/ 0.296/ 1.75/ 0.35/ 0.13/ 0.02/ 51 50 cells counted (11/26) 65/ 0.19/ 2.22/ 0.419/ 0.486/ 0.081/ 0.009/ 0.005/ 59 (11/26) 55/ 0.165/ 1.94/ 0.402/ 0.495/ 0.098/ 0.000/ 0/.005/ 50 ABG (7/27) 7.424/ 25.3/ 163.6/ 16.5/ -6.4/ 99.1 BLOOD CHEM (11/29) BUN 3.93/ crea 31/ AST 114/ ALT 89/ Ca 1.94/ Na 129/ K 3.1/ Cl 96 URINALYSIS (11/26) yellow/ clear/ SG 1.03/ pH 5.0/ CHO (-)/CHON (-)/ rbc (-)/ wbc 0-1/ Ec few/ bact rare/ mt (-) A+ CBC (11/27) 96/ 0.287/ 11.56/ 0.16/ 0.57/ 0.01/ promyelo 0.02/ blast 30/ plt 33 (11/24) 96/ 0.299/ 11.03/ 0.45/ 0.23/ 0.03/ stab 0.02/ blast 27/ plt 31 (11/21) 79/ 0.246/ 8.05/ 0.19/ 0.58/ 0.02/ blast 21/ 47 (11/7) 85/ 0.257/ 22.08/ 0.1/ 0.29/ 0.01/ myelo 0.02/ blast 0.58/ plt 44/ hypochromic/ slight poikilo/ aniso (+) (11/2) 89/ 0.259/ 34.36/ 0.04/ 0.19/ 0.01/0.01/ myelo 0.03/ blast 0.7/ atyp lym 0.02/ hypochromic/ anisocytosis (+)/ poikilo (+)/ no TG (11/1) 91/ 0.299/ 24.9/ 0.18/ 0.37/ 0.07/ blast 0.38/ 49/ hypochromic/ anisocytosis (+)/ poikilocytosis (+)/ no TG (10/30) 85/ 0.248/ 11.9/ 0.434/ 0.529/ 0.033/ 0.002/ 0.002/ 38 (10/29) 86/ 0.259/ 15.46/ 0.16/ 0.68/ 0.02/ myelo 0.01/ blast 0.13/ plt45 BLOOD CHEM (11/27) bun 2.48/ crea 44/ UA 0.24/ alb 38/ TB 0.25/ DB 0.05/ IB 0.19/ alk phos 103/ ast 23/ alt 40/ ca 2.19/ mg 0.84/ ldh 214/ Na 142/ K 3.3/ Cl 102 (11/7) rbs 4.71/ bun 3.89/ crea 48/ alk phos 103/ na 137/ k 3.9/ cl 100 (10/30) UA 0.25/ alk phos 117/ ast 16/ alt 29/ ca 2.41/ phos 1.8/ ldh 193 (10/30) bun 3.77/ crea 43/ na 140/ k 3.9/ cl 102 URINALYSIS (11/27) lt yellow/ clear/ SG 1.01/ pH 6.5/ CHO (-)/ CHON (-)/ rbc 0-2/ wbc 0-1/ ec (-)/ bact rare/ mt (-) (11/7) yellow/ clear/ SG 1.025/ PH 6.5/ CHO (-)/ CHON trace/ rbc 0-1/ wbc 0-1/ eco cc/ bact rare/ mt rare (10/30) yellow/ clear/ SG 1.03/ pH 6/ CHO (-)/ CHON (-)/ rbc 0-1/ wbc 0-1/ ec (-)/ bact rare/ mt (-) BLOOD CS (11/4) NG5D BMA Repeat CXR Ff-up final Blood CS Shift Cefuroxime to Ceftazidime (100) Amikacin (15) Diphenhydramien Paracetamol DAT IVF: D5 0.3 NaCl O2 support 10 lpm FM PNSS neb q2 Dopamine (10) Dobutamine (8) For 24 hr urine collection for TV, TP, TC Erythromycin eye ointment Multivitamins Paracetamol prn s/p BT 1 unit pRBC For chemotherapy once with meds W9 B26 CN 3406137 DOA 11/23/09 DOB 9/25/08 CAPARAS, Kyle 1/ M Wt: 4.75 kg Ht 83 cm BSA 0.47 m2 Beta Thalassemia Febrile Neutropenia CAP R/O Sepsis INTRDEPARTMENTAL REFERRALS W11(14a) B3 AYO ,Randy CN 1976844 16/M DOA 9/14/09 DOB 9/27/91 Hemophilia A, moderate (iliopsoas bleed ) Cholecytolithiasis , Urolithiasis CN DOA 11/10/09 DOB JIMENEZ, Jerome 12/M WT. 20.6 kg Clinical Nosocomial Sepsis, Resolving Abscess of Comon Bile Duct and Gallbladder secondary to Obstructive jaundice secondary to Biliary Ascariasis S/P Cholecystectomy, CBDE, T-tube (OM 2/06) T/C Beta Thalassemia R/O Chronic Liver DIsease Anemia probably secondary to Betathalassemia Malignancy URTI, bacterial PEM W11 B33 CN DOA 11/11/09 DOB ROSALES, Mac Ruvic 4months/M 6.7kg 63cm 0.34m2 Intraabdominal Mass, probably Hepatoblastoma CAP, resolved Indirect Inguinal Hernia, Left Sepsis ruled out Patient is a diagnosed case of Beta-Thalassemia since 7 months old presenting with pallor. Hgb electrophoresis done confirmed diagnosis. Since then patient is on regular follow-up c/o Hema-Onco service. Patient was apparently well until 1 week PTA when patient was noted to have productive cough. No consult done. 1 day PTAm patient developed low-grade fever associated with oral ulcer. Consult done c/o H-O OPD where Hgb 53. Patient advised admission. Diagnosed case of hemophilia A Patient with history of GB removal (?) in 2005 due to obstruction 2 months PTA, patient noted with jaundice; no consult done 3 days PTA, patient developed fever partially lysed with paracetamol 1 day- patient with decreased appetite and weakness prompting consult and subsequent admission Patient has been admitted because of jaundice and pallor. T/C Beta Thalassemia. Patient was sent home apparently well until 2 days after discharge, there was note of fever undocumented associated with cough. Persistence associated with poor appetite and note of abdominal enlargement consult admitted Born FT to a 19 y/o at Catarman Hospital assisted by MD; (+) PNCU at LHC, ?x starting at 4 months AOG; (+) MV FeSO4; (-) maternal illness, occasional colds. At birth, good cry. Good suck and activity. 4 months PTA- abdominal mass R side, no consult 1 month PTA- still with the gradually enlarging abdomen, (+) cough; consulted UTZ—hepatoblastoma Right lobe 2week PTA- (+) recurrence of cough admission (11/24) immunologic findings consistent with a blast population of myeloid lineage A+ CBC (11/27) 133/ 0.388/ 5.24/ 0.4/ 0.437/ 0.151/ 0.006/ 0.006/ 113 (11/24) 68/ 0.202/ 5.07/ 0.444/ 0.453/ 0.095/ 0.002/ 0.006/ 72 URINALYSIS (11/25) yellow/ clear/ SG 1.02/ pH 5.5/ CHO (-)/ CHON (-)/ rbc 0-2/ wbc 1-3/ ec (-)/ bact few/ mt (-) BLOOD CS (11/24) NG5D Ceftazidime (100) D4+1/7 Amikacin (`15) D4 Nystatin Paracetamol For home once antibiotics completed for 7 days O+ CBC (11/4) 107/ 0.334/ 5.3/ 0.59/ 0.34/ 0.04/ 0.02/ 239 PT/PTT (11/4) 12.8/ 12.3/ 1/ 1.18 36.3/ 94.8/ 2.61 URINALYSIS (10/22) yellow/ clear/ 1.025/ ph 7/ cho (-)/ chon 1+/ rbc 2-6/ wbc 0-1/ ec (-)/ bact few/ mt occ (10/4) yellow/ , 1.01, pH 8.5 (-) sugar CHON 2+ , RBC 2.6 , WBC 0-2 , EC (-)/ bact few / rare MT , RBC 30% normal , 30% dysmorphic ILIOPSOAS BLEED (11/27) 213cc from 273 cc (10/28) decreasing size B+ CBC (11/25) 120/ 0.353/ 6.05/ 0.796/ 0.116/ 0.081/ 0.005/ 0.002/ 136 (11/24) 94/ 0.292/ 4.44/ 0.782/ 0.181/ 0.011/ 0.021/ 0.005/ 128 (11/23) 71/ 0.224/ 8.86/ 0.81/ 0.134/ 0.046/ 0.009/ 0.001/ 175 (11/20) 98/ 0.323/ 11.11/ 0.834/ 0.089/ 0.062/ 0.013/ 0.002/ 188 PT/PTT (11/24) 38.2/ 33 (11/22) 12.4/ 14.5/ 69%/ 1.27 BLOOD CHEM (11/28) tb 10.14/ db 9.45/ ib 0.69 (11/25) rbs 9.08/ alb 19/ tb 15.2/ db 12.9/ ib 2.2/ ast 145/ alt 103/ na 140/ k 2.4/ cl 100 (11/20) rbs 6.74/ BUN 2.76/ crea 38/ UA 0.13/ alb 19/ TB 11.8/ DB 9.9/ IB 1.9/ alk phos 467/ AST 31/ ALT 67/ Ca 1.87/ Mg 0.84/ Phos 0.84 Na 142/ K 3.5/ Cl 108 URINALYSIS (11/20) yellow/ clear/ SG 1.005/ pH 5.5/ CHO (-)/ CHON (-)/ rbc (-)/ wbc (-)/ ec (-)/ bact occ/ mt (-) ABDOMINAL CT (11/25) Minimal ascites; splenomegaly For perlvic UTZ weekly B+ CBC (11/16) 96/ 0.298/ 11.6/ 0.354/ 0.518/ 0.013/ 0.115/ 193 (11/11) 116/ 0.353/ 25.58/ 0.26/ 0.60/ 0.08/ 0.03/ 0.01/ myel 0.01/ pro 0.01/ 583 PT/PTT (11/11) 13.1/11.8/>1/1.13 36.7/38.9 BLOOD CHEM UTZ guided liver biopsy if mass is nonresectable BAER 2D Echo CT guided aspiration biopsy c/o Radio For BT of 23y cryoppt/ factor VIII For EGD For Liver Biopsy For Protein C and S For osmotic fragility test 15 days from last BT For Hgb Electrophoresis 2 mons from last BT Ciprofloxacin Ibuprofen Vit K Pb UDCA Clusivol Vit E For Alb transfusion Cefuroxime (100) D14 –d/c (11/11) Glu 5.25, BUN 1.8, Cre 30, Alb 32, TB 0.25, DB 0.09, IB 0.17, AST 26, LT 29, Ca 2.29, LDH 172, Na 129, K 4.9 Cl 93 BLOOD CS (11/11) NG5D 24 HR URINE (11/27) tv 300 tc 0.043/ tp 0.21 WHOLE ABD UTZ (11/13) hepatic focus, primary consideration is hepatoblastoma, minimal to moderate complicated ascites; normal GBSKUB BHCG (11/18) < 0.08 low AFP (11/25) 39.3 (11/11) 74.95 increased Salbutamol neb q4 Breastfeeding with SAP`