Life Sciences Gr. 12 2014 – Term 1 NOTES Cut out along provided dashed border, paste in, starting on 1st left hand page. Complete questions after pages are pasted flat. Strand 1: Life at Molecular, Cellular & Tissue level Date: ____________ DNA: The code of Life First of all, some revision: Regard the labelled diagram below, and complete the functions of the indicated labelled parts. Use your textbook and prior knowledge to do this. Remember to focus on how these parts apply to what you will be studying in this section = DNA and how it carries information to form every part of all organisms on the planet. Smooth ER Nucleopore Nucleomembrane Chromatin network (DNA) Nucleolus Nucleoplasm Rough ER Ribosomes ER Nucleopore Ribosomes Nucleolus Chromatin Network 1 Life Sciences Gr. 12 2014 – Term 1 NOTES Cut out along provided dashed border, paste in, starting on 1st left hand page. Complete questions after pages are pasted flat. Location of DNA: Nucleus DNA contained within a nucleus of eukaryotic organisms. Nuclear DNA encodes for the majority of the genome in eukaryotes. Nuclear DNA adheres to Mendelian inheritance, with information coming from two parents, one male, and one female. One parent will possess a dominant genome and the other a recessive genome. When combined during fertilization, the child has the dominant characteristic visible, but the recessive characteristic is carried and possibly passed to the following generation. Mitochondrion DNA located in mitochondria and plastids coding for the rest of the remaining genome not coded for in nuclear DNA. Is inherited directly from the mother through the egg cell during fertilization. Remains unchanged through countless generations, is one of the points of evidence for the ‘Out-of-Africa’ theory when evolution is discussed. Genome: the haploid set of chromosomes in a gamete or microorganism, or in each cell of a multi-cellular organism. Mendelian: Austrian monk who first experimented with dominant and recessive inheritance. You will learn more about this when we do the ‘Genetics’ section. Haploid: meaning half of the complete set of genetic information inherited from the parents. Humans have 46 chromosomes, 23 from mother and 23 from father. The 46 full set is referred to as Diploid, the 23 half set is referred to as the haploid chromosome / genome number. Gamete: the non-specific name for a reproductive cell, either male (sperm) or female (egg cell). Gene: a unit of heredity which is transferred from a parent to offspring and is held to determine some characteristic of the offspring. Humans have numerous genes that are all located on different places on a chromosome. These gene locations are called a Locus. Heredity: the passing on of physical or mental characteristics genetically from one generation to another. There is still a lot of debate regarding the ‘mental’ characteristics being passed from parent to child. Yes there has been evidence presented that certain conditions such as Schizophrenia, Bipolarism etc. are passed from parent to child, but there has been an almost equal amount of evidence that indicates that experiences through childhood or life can trigger these conditions also. So the jury is still out on that one . Numerous studies focus on early childhood stimulation as evidence for higher IQ, not really genetics. But if the parents don’t know better (education, IQ etc.) how will they know how to properly stimulate their child’s development? It can become a nice circular argument if you wish. 2 Life Sciences Gr. 12 2014 – Term 1 NOTES Cut out along provided dashed border, paste in, starting on 1st left hand page. Complete questions after pages are pasted flat. QUESTIONS: 1) Study the data below and complete the family tree. Disregard all other factors except dominance and recessiveness of traits / characteristics. DOMINANT TRAITS RECESSIVE TRAITS eye colouring brown eyes grey, green, hazel, blue eyes vision farsightedness normal vision normal vision normal vision normal vision nearsightedness night blindness colour blindness hair dark hair non-red hair curly hair full head of hair widow's peak blonde, light, red hair red hair straight hair baldness normal hairline PETER Brown eyes PAUL MARY Blue eyes JOHN MARK SARAH Brown eyes JOHN Jnr JESSICA Green eyes 2) Do you think it is at all possible for Mark and John Jnr to have anything besides Brown eye colour? Explain your answer (shortly! This is not an essay question!) 3) What do you think would be the consequences of the nuclear membrane NOT having nucleopores? 4) Why is the relatively close location of ribosomes to the nucleus of biological importance? HOW MUCH DO YOU REMEMBER? 5) What is the chromosome difference between males and females? 6) What are the monomers of proteins? 7) Name 3 bodily structures that are formed by proteins. 3