Lesson Plan Summary Sheet
Teacher:
Howerton
Subject:
Biotech I
Topic:
Date
8/24
8/25
Unit A: The Biotech Industry
Essential Question(s)
What will we be asked to do in this
biotechnology class?
What are some applications of
biotechnology?
8/26-27
What are some historical events in the
field of biotechnology?
8/28
What has to happen for a product to
get to market?
What are some uses of biotechnology
products?
8/31-9/1
What are the different types of
companies found in the biotech
industry?
What is the structural organization for
the typical large biotech company?
What are some of the job descriptions,
education and skills needed to work in
the biotech industry?
9/2
Activities
Learning Logs
Vocabulary
Summarizing Strategy
□ Review the syllabus and discuss class expectations
□ Students will take a pretest on the course content.
□ Students will be given an application of biotech and additional
reading materials on that application
□ Students will complete the Create A Logo activity
□ Students will view the Applications of Biotechnology
powerpoint
□
□ Students will complete the History of Biotech Scavenger Hunt.
□ Students will view a video and presentation on the history of
biotech
□ Students will have a Edmodo quiz on some historical
characters of biotech
none
Students will visit the “Viagra Story” website by Pfizer
Students will view the Drug Development powerpoint
Students will create a drug development poster
Students will look up and profile a product made by biotech
companies and create a visual for display
□ Students will view the Biotech Industry powerpoint
□ Student groups will start on the Biotech Entrepreneurship Grant
Award (BEG) project.
□ Students will present their powerpoint to the class
In vitro
Clinical
Efficacy
□
□
□
□
□ Students will continue to work on the BEG project by looking
up job descriptions for the biotech related careers given.
□ Students can use the graphic organizer to help them organize
their information.
□ The Honors Research Project topics are due today
Biotechnology
Diagnostics
Therapeutics
Pharmaceuticals
Aquaculture
Biocatalysts
A1: Explain what you
expect our of this class.
A2. Explain the “colors” of
biotechnology.
A3. Describe the connection
between science and
technology and the biggest
driving force for new
discoveries in the field of
biotechnology.
A4: Explain the process of
drug development from the
initial idea until it is brought
to market.
A5. Compare and contrast
the organization of a biotech
company with the
organization of a school.
A6. Describe the biotech job
that you find the most
interesting and explain why.
9/3
What are some biotechnology tools
used to create biotech products
□ Students will visit the Guide to Biotechnology 2008 to help
them learn about the biotech tools listed in the BEG project.
□ Students will work to complete the proposal portion of the
BEG project.
See activity
A8: Explain which biotech
tool interests you the most
9/4
How do we develop a personal career
plan?
What is the financial perspective of a
biotech company?
What is the outlook for biotechnology
in the Triad and NC?
□ Students will complete the career planning activity.
Resume’
□ Students will begin a long-term stock market project where
they will follow the stock of a selected biotech company.
□ View some videoclips and write a news article on biotech in
NC and the Triad.
varies
9/9
What goes on in the biotech industry?
□ Wrap-up and Review
□ The BEG group project is due
none
9/10
What goes on in the biotech industry?
none
9/11
How do you write a research paper
□ Learning Log answers are due
□ Unit A Test – Multiple Choice
□ Students will hear presentation on writing a research paper
and then begin on the Lessons on Writing a Research Paper
assignment
A7. Briefly describe your
career plan.
A9: Write a brief article for
the school newspaper about
biotechnology to help the
average student understand
it.
A10: Write a reflection
about your effort on this
unit and how you can
improve.
none
none
none
9/8
Create A Logo
As a group, you will be given some material to read that describes a specific application in
biotechnology. After you have read this material, your group is to create a fictitious company
and a product that would an example of your assigned biotech application. You will will:

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
Create a Company name
Create a logo for your company
Decide on a problem that your company could address with a product specific to your assigned
biotech application
Describe how your company’s product would help solve the problem
Decide who this product would be sold to (general public, patients, farmers, doctors/vets,
companies ,etc) and what media source you would use to market it.
Create a final print advertisement that presents the information above.
You will present your application to the class by 1) summarizing your assigned biotech
application and 2) explaining your designed company and product
Biotechnology History Scavenger Hunt
1. What is biotechnology and what is the earliest use of a biotechnology process, still used today, can
you identify?
2. What happened in the late 1600s that led to a much better understanding of bacteria? Who was
responsible for this discovery?
3.
Who is the person who first “coined” the term biotechnology?
4. When was the first large scale production of penicillin achieved and name at least 3 diseases
penicillin is used to treat.
5.
What major milestone was achieved in 1953 and who is credited with this milestone?
6. What did Marshall Nirenburg work on for 5 years and why is it important to the history of
biotechnology?
7. When was the North Carolina Biotechnology Center created and what was is its purpose?
8. What did Genentech/Roche produce in 1978 from E. coli? What other product did they produce for
the treatment of diabetes?
9. In 1980 the US Supreme Court ruled on a landmark case Diamond v. Chakrabarty. What was
decided by this case?
10. In what year was the first DNA fingerprinting technique developed?
11. What does PCR stand for? In what year was the method first conceived? In year was the procedure
first published?
12. In 1991 a biotech company, Amgen, developed Neupogen. What was the significance of this
discovery? Record the website for later on
13. What milestone was achieved by Genzyme in 1991? Name the product and the disease it treats.
Record the website for use later on.
14. In what year was the first baboon to human bone marrow transplant performed? What disease did
the patient have?
15. Biogen, located in Cambridge, MA and RTP, NC, produced Avonex. What disease is this a treatment
for?
16. Dolly came on the biotech scene in 1997. How was she significant?
17.
In what year did bio-defense become particularly important to a point where
federal funds were approved to support research and development efforts? What specific
incidence led to this?
18. What major milestone was completed in April 2003?
19. Monoclonal Antibodies:
20. Recombinant DNA technologies:
21. What major case has the company Myriad been involved within the last year?
22. What is the Piedmont Triad Research Park?
23. Who was the PTRP’s first major tenant? What do they do?
24. What are some of the highlights of Dr. Anthony Atala?
25. What is the most interesting item presented in the www.triadbiotech.org video?
Some helpful websites: www.genzyme.com, www.accessexcellence.org, www.ncbiotech.org, www.biogen.com,
www.amgen.com, www.gene.com
Biotech Product Profiles
Choose from one of the following biotech products to research. Create a visual profile for the
product.
Activase
Agrisure Viptera
AlgaBerry
Aspartame
Avastin
Avonex
Beano
Bio-Flex plastics
Bollgard
Chymogen
Depol 686L
Dyneema Purity
EPOGEN
Fermasure
FlvrSavr Tomatoes
Greensulate
HFCS42
Humira
Humulin
IndiAge
Liberty Link Corn
M-Pede
OzzyMat
Premise 75
Primagreen
Purafect
Recombivax
Rocephin
Round-up Ready Corn
Spirizyme
Versazyme
Videx
XenoMouse
Include the following information
in a visual on a single sheet of
paper. Use 20-28 font if possible
□ Product name
□ What it does (description)
□ Company
□ Picture
□ Value/$ (if available)
□ Other relevant info
The Biotech Entrepreneurship Grant Award Application Check List
Request For Proposal:
The Biotech Entrepreneurship Grants support the inception of small companies that
research and develop innovative products and services in the areas of: bioprocessing, protein
engineering, tissue engineering, biosensor technology, biodegradation/bioremediation,
recombinant DNA technology, or biofuels. Awards are intended to help fund initial personnel
for a start-up company. The first phase of the grant is to write a Pre-Proposal. Full Grant
Proposals will be by invitation only. The maximum amount awarded will be $5,000,000.
Instructions for Pre-Proposal:
Part I Due Diligence
The first step in this process is to show due diligence. You have to prove that you have
researched and studied successful companies and know what is required to make your company
successful. This includes setting up the appropriate organizational structure for your company.
1. You must select an existing public biotechnology company. See the list below of possible
companies to pick from or choose one of your own interest (get approval).
Abbott
Amgen
Astrazeneca
Bayer Health Care
Biogen
Bristol-Myers Squibb
Genentech
Genzyme
Gilead
GlaxoSmithKline
Johnson & Johnson Merck
Novartis
Pfizer
Roche
Sanofi
Wyeth
2. Each person on your team must assume the role of a different executive in this company
3. Your report to the class will include at least the following information via powerpoint.
□ Company Name
□ Product listing (list the types of products such as cancer, diabetes, arthritis, etc.)
□ Stock market symbol and where traded (NASDAQ/NYSE)
□ Stock price (as of today but you will need to follow it over time*)
□ Global presence of company
□ Job descriptions for your titles
□ Names of actual individuals who hold your position
□ Salaries of the people who hold your positions and bonus plans
□ Some products currently under development or in the R&D pipeline
□ Company Logo (include this in your presentation)
□ Important or interesting facts about the company (size, when founded, location, )
□ Any news clippings or press releases during recent months
4. Create a list of possible job descriptions along with education requirements and salary that might be
considered in a typical biotech company. You can use a graphic organizer for this. A list of
possible careers are:
Research scientist, Quality Control, Quality Assurance, Bio-Processing Engineer, Bio-Statistician,
Metrologist, Regulatory Affairs, Clinical Affairs, Biomedical Engineer, Intellectual Property Officer,
Maintenance & Instrumentation Technician, Patent Lawyer, Sales & Marketing
5. Write a brief explanation of each of the following: bioprocessing, protein engineering, tissue
engineering, biosensor technology, biodegradation/bioremediation, or biofuels
Part II. Your Proposal
You also know how products such as drugs are developed. Now decide which biotech tools
listed in bold print above you want to create a start up company around. Find or create a
problem that needs a solution that your company can develop a product for. You then will need
to apply for this grant in order to get the necessary funds to get this company off the ground.
Address each of the components below in your grant proposal. Have each team member initial
the components that were responsible for doing.
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Title Page with Grant Proposal Title, Company Name, Logo, and Names
Table of Contents
Abstract (brief description of the proposal – 100 words or less)
Significance (describe the problem that your company can help solve and how the
products that you will develop will do this)
Project Plan (an outline of the process for which you research and develop your product,
including a time line)
Budget Justification (provide the yearly salary and job description for each of the 10
employees you decide are the most important to start out with, including your own)
Diversity (The grant supports the hiring of a diverse group of workers so explain how
you will achieve this)
Biographical Sketches (for each member of this grant proposal team, provide the job title,
job description, highest degree held, educational institutions, college major, relevant
college courses taken, and high school preparation)
You will be graded on the quantity and quality of your information as well as the professionalism
of your presentation and proposal. You must do the best job you can do with the time that you
are given. The deadline for the proposal and presentation is Wednesday, September 12 at
10:45am
3- Work is of high quality and sufficient information to suggest a successful understanding of the topic is most
likely
2- Work is of good quality with lots of information to suggest that a successful understanding of the topic is
probable.
1 – Work is of poor quality with little information to suggest that a successful understanding of the topic is unlikely.
0 – Work is not turned in.
Biotech Career Opportunities
Job Title
Research
scientist
Quality Control
Quality
Assurance
Bio-processing
Engineer
Bio-Statistician
Metrology
Regulatory
Affairs
Clinical Affairs
Biomedical
Engineer
Intellectual
Property
Officer
Maintenance &
Instrumentation
Technician
Patent Lawyer
Sales and
Marketing
Forensic
Psychiatrist
Forensic
Pathologist
Job Description
Education
Training
Salary
Career Planning Activity
Activity 1: What is your career goal?
 Description of career
 Education required include total number of years until you are employed
 Salary (starting salary)
 3 important characteristics or skills needed to be successful in this job
 Why do you think this is a good choice for you?
Activity 2: Research 3-5 colleges which offer your major: Choose one college and:
 List some course requirements (some upper level courses)
 Record admissions information (SAT, GPA etc)
 Record cost of attending each college (in state or out of state)
Activity 3: Brainstorm what is required before you can apply to college and ways to pay for
college
Activity 4: Develop a career planning timeline
Using details from Activities 2 and 3 develop a detailed timeline of events

Include application dates, acceptance dates, etc.

Identify at least 3 scholarships you are eligible to apply for
Activity 5: Develop a resume and then write an answer to the following essays

Choose a societal issue/concern/problem and then explain how acceptance
into this program can help you find a potential solution to it.

List one strength and one weakness you have that will affect your college
experience and how you will address them to assure your success.
Possible Source: www.cfnc.org
Biotech Stock
You have been given $10,000 by your late Uncle Morty to invest in a biotech company. You are
to:
□ Research several Biotech companies that trade on the NASDAQ to determine who has
the best history and who would be the best investment
□ Choose a biotech company
□ Record the stock market symbol
□ Record its stock market price as of today on the chart below.
□ Record a profile (graph) of past market performances
□ Record its stock market price once a week for the next 8 weeks.
□ Report this information in a data table and create a graph of the stock prices each week.
□ On Oct 28, sell your stock and report your profit/loss on the graph.
□ Turn in all your stock portfolio on October 29
To find companies in the NASDAQ Biotechnology Index, go to
http://en.wikipedia.org/wiki/Category:Companies_in_the_NASDAQ_Biotechnology_Index
Number of stocks purchased: ______
Total amount your stock purchase is worth: _______
Price per stock on Sept 9: ______
Price per stock on Sept 16: ______
Price per stock on Sept 23: ______
Price per stock on Sept 30: ______
Price per stock on Oct 7: ______
Price per stock on Oct 14: ______
Price per stock on Oct 21: ______
Price per stock on Oct 28: ______
Amount your stock sales were worth: ______
Amount of money you made: ______
Making A Difference Video Questions
Atkins 2007 series
30,000 High Paying Jobs
1. How long will it take to complete the Piedmont Triad Research Park?
2. What are three companies associated with the PTRP and what do they do?
3. What is the salary range for jobs in the PTRP?
High School Student Searches for New Drugs
4. Why does Targacept participate in student internships?
5. What is Targacept’s perception of students?
6. What benefits did the student get from participating in the internship?
Growing Organs
7. Why grow organs in a lab?
8. What is one big concern that Dr. Atala has about the future of science?
9. What kinds of education do scientists working in WFIRM have?
Stem Cells
10. What are stem cells?
11. What new source of stem cells did research scientists at Wake Forest Institute of
Regenerative Medicine discover?
12. What challenges does growing organs in a lab present?
A Great Fish Story
13. What kind of product does the company Aqualutions make?
14. When and how did the CEO of this company come up with this idea?
A Whale of a Tale
15. What kind of products do Cook Medical make?
16. What kind of professionals must work together to create these products?
17. What was the problem that they were presented with?