“The Dilemma of Difficult Diseases: Cell Therapies to the Rescue?” AGENDA Thursday, September 17, 2015 Time 7:30 am – 8:00 am 8:00 am - 8:15 am 8:15 am – 8:45 am 8:45 am – 9:15 am 9:15 am – 9:45 am 9:45 am– 10:15 am Speaker Breakfast Welcome and Introduction Keynote Speaker: Mark Holterman, MD, PhD Richard Burt, MD 10:15 am – 10:45 am Yong Zhao, MD, PhD Bellur Prabhakar, PhD Mark Holterman, MD, PhD Adeeb Al-Zoubi, PhD Yong Zhao, M.D, PhD Break 10:45 am- 11:30 am Adeeb Al-Zoubi, PhD 11:30 am – 12:00 pm International Guest Speaker: Brig. Gen. Dr. Hazem Habboub Royal Medical Services, Jordan 12:00 pm – 1:00 pm 1:00 pm – 1:45 pm Lunch Leslie Miller, MD 1:45 pm – 2:30 pm Wade McKenna, DO 2:30pm – 2:45pm 2:45 pm – 3:30 pm Break Damiano Rondelli, MD 3:30 pm – 4:15 pm Tracey Bonfield, MD, PhD 4:15 pm – 4:30 pm A Patient and Family Perspective 4:30pm - 5:00 pm Open Forum: Discussion of the Promises of Cell Therapies. Closing Remarks/Adjourn 5:00 pm Presentation The Drake Room Mark Holterman, MD, PhD The Spectrum of Cell Therapies Addressing Difficult Diseases Stem Cell Therapy for Auto Immune Disease Cell Therapy for Alopecia Areata Can Cell Therapies be Used to Treat Auto Immune Disease? Audience “Free For All” Referee: Damiano Rondelli, MD Treatment of Type 1 Diabetes With Immunomodulation and Autologous Purified Stem Cell Transplantation: The Jordanian Experience Delivery of Purified Autologous Stem Cells Into Pancreatic Arteries Via Interventional Radiology: Our Experience at The Royal Medical Services Cardiovascular Disease and Cellular Therapy Cellular Therapy for Orthopedic Conditions Bone Marrow Transplant Treatments for Sickle Cell Disease Cystic Fibrosis and MSCs Miranda Hebert Kathy Hebert Moderator: Mark Holterman, MD, PhD Mark Holterman, MD, PhD “The Dilemma of Difficult Diseases: Cell Therapies to the Rescue?” AGENDA Friday, September 18, 2015 Time 7:30 am - 8:00 am 8:00 am – 8:45 am Speaker 8:45 am –9:30 am Breakfast Keynote Speaker: Arnold Caplan, PhD Nadia Benkirane-Jessel, PhD 9:30am –10:15 am Carlo Tremolada, MD 10:15am –10:45am 10:45am –11:30am Break Keynote Speaker: Robert Harman, DVM, MPVM 11:30am –12:00pm Andrew Ittleman, Esq. 12:00 pm –1:00 pm 1:00 pm - 1:30 pm Lunch William Frey, II PhD 1:30 pm – 2:00 pm Lusine Danielyan, MD 2:00 pm – 2:30 pm William Frey, II, PhD Yong Zhao, MD, PhD Lusine Danielyan, MD 2:30 pm – 3:00 pm 3:00 pm – 3:15 pm 3:15pm – 3:45 pm Break Sammy Jo Wilkinson Naomi Lopez-Bauman 3:45 pm – 4:15 pm Nirav D. Shah, MD, JD 4:15 pm – 4:45 pm Panel and Attendee Discussion: Advancing Cellular Therapies in US through AACT Presentation Adult MSCs Manage the Body’s Innate Regenerative Capability Osteoarticular & Dental Regenerative Nanomedicine Lipogems Tissue Transfer: Basic Science and Therapeutic Applications Explained One Medicine in Action: Real data from naturally occurring diseases of animals in support of human regenerative medicine Regulatory Environment Explained Intranasal insulin, stem cells and T cells bypass the blood-brain barrier to treat CNS disorders while reducing systemic exposure Intranasal cell therapy for Alzheimer’s, Parkinson’s and Glioma Neurodegenerative Disorders Audience “Free For All” Referee: Mark Holterman, M.D., Ph.D. A Patient’s Perspective (Video) Goldwater Institute: Director of Healthcare Policy Director, Illinois Dept. of Public Health Andrew Ittleman, Esq. Nirav D. Shah, MD, JD Naomi Lopez-Bauman Leslie Miller, MD Audience “Free for All” Referee: Mitchell Fuerst 4:45 pm – 5:00 pm 5:00 pm Closing Remarks Adjourn Mark Holterman, MD, Ph.D.