July 5, 2011 Fact Sheet Little, Susan – GLAUCOMA – Optic Nerve Atrophy FACTS: Optic Atrophy Definition The optic nerve carries images of what we see coded as electrical impulses, from the retina to our brain. The optic nerve is like a cable of more than a million tiny electrical wires, or nerve fibers each carrying a part of the visual information. If these nerve fibers become damaged the brain doesn't get all the vision information and our sight becomes blurred. Optic atrophy means the loss of some (resulting in little visual change) or most (resulting in severe visual loss) of the nerve fibers in the optic nerve. Many diseases and disorders can lead to optic atrophy or damage to one or both optic nerves. Optic atrophy can occur in people where the optic nerve or nerves did not develop properly. It may also result from inflammation of the optic nerve or from glaucoma when the pressure inside the eye remains too high. In unusual cases, poisons, vitamin deficiencies, or tumors may be responsible. Most commonly, optic atrophy simply occurs without a known or proven cause. Symptoms Blurred vision Abnormal side vision Abnormal color vision Poor constriction of the pupil in light Decreased brightness in one eye relative to the other The symptoms described above may not necessarily mean that you have optic atrophy. However, if you experience one or more of these symptoms, contact your eye doctor for a complete exam. Treatment The optic nerve enters the back of the eye where it appears as a small disc, which your ophthalmologist can examine by looking through the pupil of your eye with a special instrument called an ophthalmoscope. If optic atrophy is present, this small disc will appear pale or white, indicating loss of nerve fibers. If you show some of the symptoms listed above, your ophthalmologist may decide to perform additional tests. Unfortunately, there is no effective treatment for optic atrophy. Once the nerve fibers in the optic nerve are lost they never heal or grow back. Therefore, the best defense is an early diagnosis because if the cause can be found and corrected, further damage can be prevented. Source: http://www.kellogg.umich.edu/patientcare/conditions/optic.atrophy.html IMAGE SOURCE PAGE: http://telemedicine.orbis.org/bins/content_page.asp?cid=735-28584396-2862-2864-3904 Symptoms of Optic nerve atrophy: The list of signs and symptoms mentioned in various sources for Optic atrophy includes the 3 symptoms listed below: Loss of vision Pale optic disk Impaired pupil reaction Source: http://www.wrongdiagnosis.com/o/optic_atrophy/symptoms.htm?ktrack=kcplink#symptom_list More on Optic nerve atrophy Optic nerve atrophy is damage to the optic nerve. The optic nerve carries images of what we see from the eye to the brain. Causes There are many unrelated causes of optic atrophy. The most common cause is poor blood flow, called ischemic optic neuropathy, which most often affects elderly people. The optic nerve can also be damaged by shock, various toxic substances, radiation, and trauma. Various eye diseases, most commonly glaucoma, can also cause a form of optic nerve atrophy. In addition, the condition can be caused by diseases of the brain and central nervous system, such as: Brain tumor Cranial arteritis (sometimes called temporal arteritis) Multiple sclerosis Stroke There are also several rare forms of hereditary optic nerve atrophy that affect children and young adults. Symptoms Optic nerve atrophy causes vision to dim and reduces the field of vision. The ability to see fine detail will also be lost. Colors will seem faded. The pupil reaction to light will diminish and may eventually be lost. Exams and Tests Optic nerve atrophy can be seen during a complete examination of the eyes. The examination will include tests of: Color loss Pupil light reflex Tonometry Visual acuity You may need a complete physical examination and specific tests. Treatment Damage from optic nerve atrophy cannot be reversed. The underlying disease must be found and treated, if possible, to prevent further loss. Rarely, conditions that lead to optic atrophy may be treatable. Outlook (Prognosis) Vision lost to optic nerve atrophy cannot be recovered. If the cause can be found and controlled, further vision loss and blindness may be prevented. It is very important to protect the other eye. Possible Complications Complications are related to the disease that causes the atrophy. When to Contact a Medical Professional Patients with optic nerve atrophy will be closely monitored by an ophthalmologist who has experience in neuro-ophthalmology. Tell your doctor right away about any change in vision. Prevention Many causes of optic nerve atrophy cannot be prevented. Ways to protect yourself include: Older adults should have their health care provider carefully manage their blood pressure. Prevent injuries to the face by using standard safety precautions. Most injuries to the face are related to motor vehicle accidents and can be prevented by using seat belts. Schedule a routine annual eye exam to check for glaucoma. Methanol, which is found in home-brewed alcohol, can cause optic nerve atrophy in both eyes. Never drink home-brewed alcohol and forms of alcohol that are not intended for drinking. Source: Medline Health - http://www.nlm.nih.gov/medlineplus/ency/article/001622.htm