Gas Regulation Breathing rate mainly depends on the amount of carbon dioxide in the blood (not oxygen as you would probably think!). INCREASE When carbon dioxide levels increase, the blood becomes more acidic. Chemoreceptors in the brain and major arteries coming out of the heart (aorta and carotid artery) sense this change. The brain sends signals to the diaphragm and rib cage muscles to work harder (increases respiration rate) to get rid of the extra carbon dioxide. DECREASE If CO2 levels are low chemoreceptors in the brain and major arteries coming out of the heart (aorta and carotid artery) sense this change. The brain sends different signals to the diaphragm and rib cage muscles to slow down (decreases respiration rate). CONTROL CENTER: What sends out a signal? EFFECTOR: What changes? What’s the effect? SENSOR: What changes? What senses it? SET POINT SENSOR: What changes? What senses it? EFFECTOR: What changes? What’s the effect? NOTE: In general, carbon dioxide (CO2) and oxygen levels in the blood are opposites. Oxygen is being continually used by cells so its concentration in the blood decreases naturally. In contrast to carbon dioxide, oxygen concentration needs to fall significantly before any increase in breathing rate results. The body mainly uses carbon dioxide levels to control breathing rate. CONTROL CENTER: What sends out a signal? EFFECTOR: Thermoregulation (Temperature) CONTROL CENTER: The process of maintaining a steady body temperature under a variety of conditions is known as thermoregulation. The hypothalamus protects the body’s internal organs by monitoring temperature. activates the INCREASE When thermoreceptors in the hypothalamus receive information that the temperature of the blood is rising, it sends a signal to the sweat glands causing them to release sweat to help cool the body. In addition, the hypothalamus activates the adrenal glands. The adrenal glands release a signal telling the blood vessels to relax and dilate bringing more hot blood to the surface so heat can escape. The same signal also goes to the heart and lungs causing an increase in heart and breathing rates. All of these activities carry heat away from the center of the body to the surface, where excess heat can escape. EFFECTOR: EFFECTOR: SENSOR: SET POINT SENSOR: DECREASE When the temperature of the blood falls too low, thermoreceptors in the hypothalamus receive the information. A signal from the hypothalamus causes the skeletal muscles to perform small, rapid contractions (shivering). Then, the hypothalamus activates the adrenal glands. The adrenal glands release a signal telling the blood vessels in the skin to constrict, reducing blood flow to prevent loss of heat. The hypothalamus also activates the pituitary to send hormone signals to the thyroid to increase production of thyroxine hormone which speeds up metabolism. When metabolism speeds up, more heat is generated. These activities reduce the loss of heat to the environment and increase body heat. CONTROL CENTER: activates the and the EFFECTOR: EFFECTOR: EFFECTOR: Osmoregulation (Water) EFFECTOR: CONTROL CENTER: Osmoregulation is the regulation of water concentration in the bloodstream. Water follows salt so salt regulation contributes to water regulation. SENSOR: INCREASE When water levels rise above the normal range, osmoreceptors in the hypothalamus in the brain sense increased water concentration and decreased solute concentration (meaning there’s not much salt in the blood). The hypothalamus stops making a hormone. Without this hormone, kidneys reabsorb less water and more urine is produced to get rid of the extra water. At the same time, stretch receptors in the heart sense increased blood volume (blood has lots of water). Heart muscle cells send a signal to the kidney telling it to excrete sodium. Water follows salt, so water leaves with the salt lowering water levels in the body. DECREASE When water levels drop below normal range (by sweating), the osmoreceptors in the hypothalamus in the brain detect higher concentration of salts in the blood (lower concentration of water). The hypothalamus releases a hormone it made through the pituitary. This signal causes the kidney to reabsorb more water (reducing the amount that becomes urine) and creates a feeling of thirst. The person drinks water to return water levels to normal. At the same time, stretch receptors in the heart sense that there is low blood volume. They tell the adrenal glands to release a signal to the kidney. This signal causes the kidney to actively reabsorb sodium. Since water follows salt, more water is returned to the body rather than excreted in urine. CONTROL CENTER: EFFECTOR: SENSOR: SET POINT SENSOR: SENSOR EFFECTOR: CONTROL CENTER: EFFECTOR: CONTROL CENTER: This shows how water is reabsorbed into the body rather than released as urine. EFFECTOR: