2141591 Cell and Molecular Biology (3 credits)
Instructors: Pimpon Uttayarat, Ph.D. (Course Coordinator)
Kanokporn Boonyasirichai, Ph.D.
Suwimol Jetawattana, Ph.D.
Siraprapha Sanchatjate, Ph.D.
Textbook: Molecular Biology of the Cell 4th edition by Alberts et al., Garland Science 2002. (textbook available
to download from pubmed website)
Supplemented reading materials: selected journal paper
Course objectives: The objective of this course is to introduce students to basic concepts in cell
biology, cellular biochemistry at the molecular level, and current topics in stem cells and cancer.
Cellular structures and functions that comprise major tissue types in human body are explored.
Mechanisms underlying cell adhesion, cell division, cell signaling, DNA synthesis, RNA synthesis and
protein synthesis are examined in details at the molecular level. The role of immune system is
investigated. Relevant topics in stem cells and cancer will be discussed in the context of basic
concepts in cell biology.
Topics covered: Basic concepts in cell biology and cellular biochemistry, cell structures and organelle
function, protein structures and functions, DNA synthesis, RNA transcription, protein translation,
gene regulation, membrane structure, cell receptor, cell adhesion and signaling, cytoskeleton, cell
motility and molecular motors, nervous system, connective tissue, immunology, techniques in cell
biology, stem cells, tumor and cancer.
Grading:
Presentation
Quizzes/Homework
Midterm
Final
20%
20%
30%
30%
Lecture
14 August 2010
Instructor
PU
Topic and assigned reading
Cellular biochemistry: pp 4-91 and pp 110-123
Cell structures and organelle function: Chapter 12
Protein structure and function: Chapter 3
21 August 2010
KB
DNA synthesis: Chapter 4-5
RNA transcription: Chapter 6, pp 320-335
28 August 2010
KB
Protein translation: Chapter 6, pp 335-373
4 September 2010
KB
Gene regulation: Chapter 7
Cell cycle: Chapter1 7
11 September 2010
PU
Membrane structure and receptors: Chapter 10 pp 583-643
18 September 2010
PU
Cytoskeleton: Chapter 16, pp 907-948
25 September 2010
PU
Cell adhesion and extracellular matrix: Chapter 15, pp 1066-1112
Cell motility and molecular motors
2 October 2010
Midterm Exam (3h exam)
9 October 2010
SJ
Tumor cells and the onset of Cancer
16 October 2010
SJ
Oncogenes, hypoxia and free radicals
30 October 2010
SS
Stem cells and its application in regenerative medicine (journal paper)
6 November 2010
SS
Techniques in cell biology : Chapter 8, 9
13 November 2010
SJ
Introduction to Cell Culture
20 November 2010
SS
Immunology
27 November 2010
PU
Presentation
9 ตุลาคม 2553
อาจารย์สุวมิ ล เจตะวัฒนะ
16 ตุลาคม 2553
อาจารย์สุวมิ ล เจตะวัฒนะ
30 ตุลาคม 2553
อาจารย์สุวมิ ล เจตะวัฒนะ
6 พฤศจิกายน 2553
อาจารย์ศิรประภา สัญชาตเจตน์
13 พฤศจิกายน 2553
อาจารย์ศิรประภา สัญชาตเจตน์
20 พฤศจิกายน 2553
อาจารย์ศิรประภา สัญชาตเจตน์