SCIENCE DEPARTMENT As Biology Syllabus 9700 for exams in 2016 Year 12 Scheme Of Work 2015-2016 Term 1 Units Taught Unit 1 Cells and the Mitotic Cell cycle. Curriculum/Syllabus covered Section 1-Cell structure: Light and electron microscopes; Using graticules and stage micrometers to calculate magnification of drawings and measuring cells; structure and function of organelles in animals and plants; characteristics of eurkaryotic and prokaryotic cells; structure of a virus. Section 5- The Mitotic cell cycle: Replication and division of nuclei and cells; behavior of chromosomes in mitosis; stem cells; cancer. Unit 2 Section 2-Biological molecules: Structure of carbohydrates, proteins Biological and lipids, and their roles in living organisms; Water and living organisms; Molecules biochemical tests. Unit 3 Section 4- Cell membranes and transport: Fluid Mosaic model of Cell membranes and membrane structure; movement of substances in and out of cells passive Transport across and active methods. membranes Unit 4 Section 3- Enzymes: Mode of action of enzymes; factors that affect Enzymes enzymes; enzyme kinetics. 2 Unit 5 Nucleic Acids and Protein Synthesis Unit 6 Transport in plants Unit 7 Transport in Mammals and Gas exchange Unit 8 Infectious disease and immunity 3 Section 6- Nucleic acids and protein synthesis: Structure and replication of DNA; role of DNA in protein synthesis. Section 7- Transport in plants: The need for a transport system in flowering plants; structure of transport tissue; transport mechanisms. Section 8- Transport in mammals: The circulatory system; structure and function of blood, blood vessels and the heart; role of haemoglobin; control and co-ordination of the cardiac cycle. Section 9- Gas exchange and smoking: The gas exchange system; smoking and smoking-related diseases. Section 10- Infectious disease: Causative agents, transmission and prevention of cholera, malaria, tuberculosis (TB), measles and HIV/AIDS, and their global importance; eradication of smallpox; antibiotics. Section 11- Immunity: The immune system; auto-immune diseases; mode of action of phagocytes and lymphocytes; antibodies; vaccination Revision AS Biology 2015-2016 –Proposed List of Practical’s ( this list is not exhaustive, and other practical lessons can be added) Term 1 Unit Unit 1 Cells and the Mitotic Cell cycle. Practical 1. Investigation into size and scale of microscopic tissues (AS practical skills – practical 1, p27) 2. Microscopic observation of cells and tissues (AS practical skills –practical 2, p33) 3. Preparing and measuring onion cells (worksheet) 4. Broad bean root tip squash (AS Practical Skills, Practical 8, p67) Unit 2 Biological Molecules 1. Testing for the presence of reducing sugars Practical 17, p57 Comprehensive Practical biology for A levels, 2. Testing for the presence of starch – practical 16 p56 ‘Comprehensive Practical Biology for A levels’ 3. Testing for the presence of nonreducing sugars Intended outcome Using a compound microscope with an eyepiece graticule and stage micrometer. Calibrate an eyepiece graticule with a stage micrometer Use the calibrated graticule to determine the actual sizes of cells and tissues using both low and high power objective lenses. Use a compound microscope. Make clear and accurate plan and cellular drawings of biological tissue Be able to interpret structures seen through the microscope. Preparing and mounting a specimen on a microscope slide. Calibrating an eyepiece graticule Measuring the size of onion cells. Making clear and accurate cellular drawings. Experience simple techniques to observe mitosis in cells in the root tip of broad beans. Extend knowledge on the structure and function of mitosis. Interpret and record observations. Understand and carry out the procedure of benedicts test for reducing sugars. Be able to carry out serial dilutions. Be able estimate concentration of reducing sugar qualitatively Be able to carry out a starch test to identify presence of starch. Observe and explain the starch-iodine mixture under a miscroscope. Identify starch grains in potato using a microscope Understand and carry out the procedure for non-reducing sugars. Comprehensive ‘Practical biology for A levels’ Practical 17 p57 4. Testing for the presence of lipids and proteins ‘Comprehensive Practical biology for A levels’ Practical 18 (a) and (b), p59 5. The identification of biological chemicals present in solutions (practical 3- AS Practical skills p40) Be able to carry out and explain the Biuret test for proteins and smear and emulsion test for lipids. Decide what tests to carry out and what observations to make. Use an appropriate means to record observations, constructing any tables before you make observations. Describe and summarise the key points of your observations Draw conclusions in terms of the presence or absence of different chemicals in the solutions. Suggest alternative strategies for identifying some of the materials. Experience relevant methods, analysis, conclusions and evaluation. Describe and explain the relationship between temperature and the permeability of cell membranes. Unit 3 Cell membrane s and Transport across membrane s Unit 4 Enzymes 1. The effect of temperature on membrane permeability in beetroots. ‘AS Practical Skills, Practical 7, p62. 2. Water potential of plant cells – Practical 12, p41 ‘Comprehensive practical biology for A Levels’ 3. Past paper question 1 1. The effect of pH on enzymes –p51, Practical 5, AS Practical skills. Experience relevant methods, recording, analysis and evaluation. Be able to estimate the water potential of plant tissue. Be aware of and practice the ‘wet’ type of question 1 in AS practical exams. Identify dependant and independent variables Make a hypothesis and express this in words and graphically Experience relevant methods, analysis and conclusions Term 2 Unit 5 Nucleic Acids and Protein Synthesis Unit 6 Transport in Plants 2. The effect of inhibitors on enzyme activity. Practical 6, p57, AS Practical Skills. 3. Investigation of the different carbohydrates metabolized by yeast. AS Practical Skills, p45, practical 4. ASSESSED PRACTICAL 1. The extraction of DNA from onions. AS Practical Skills, Practical 9, p73 2. The effect of wind speed on the rate of transpiration in a leafy shoot. AS Practical Skills, Practical 10, p78 3. Past paper question 2 on plant tissue Unit 7 Transport in mammals and gas exchange 1. The structure of the mammalian heart. Practical 61, p173, ‘Comprehensive practical biology for A Levels’ Describe the relationship between pH and enzyme activity. Evaluate procedures. Experience relevant methods, analysis, conclusions and evaluation. Describe and explain the effect of a non competitive inhibitor. Experience relevant methods, analysis, conclusions and evaluations. Describe and explain the relationship between temperature and the permeability of cell membranes. Experience simple techniques to extract DNA from living materials. Extend knowledge about structure of DNA. Identify dependent and independent variables. Make a hypothesis and express this in words and graphically. Identify the variables that should be controlled. Experience relevant methods, analysis and conclusion. Describe and explain the relationship between transpiration and wind speed. Evaluate procedures. Identifying structures under the microscope Drawing plan diagram and high power cell diagram. Measuring cells or calculating magnification. Experience relevant methods, analysis and conclusion. Describe and explain the relationship between structure and function of the mammalian heart. 2. Microscopic structure of blood vessels. Practical 62, p175, ‘Comprehensive practical biology for A Levels’ Be able to interpret structures seen through the microscope. Describe and explain the relationship between structure and function of arteries, veins and capillaries.