毒物药物研究所 2014 年度发表 SCI 论文汇总
1.Zhong W1, Zhu H2, Sheng F3, Tian Y4, Zhou J1, Chen Y5, Li S1, Lin J6.
Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the
transcription of autophagy genes in response to oxidative stress induced by a novel
copper complex in HeLa cells.
Autophagy, 2014 Jul, 10(7):1285-300.(SCI IF=11.423) PDF 1-52.
2.Yang,-Y; Yang,-Y; Xie,-X; Cai,-X;Zhang,-H;Gong,-W; Wang,-Z; Mei,-X.
PEGylated liposomes with NGR ligand and heat-activable cell-penetrating
peptide-doxorubicin conjugate for tumor-specific therapy.
2014 May;35(14):4368-81.( SCI IF=8.312) PDF 1-112.
3. Cheng,-X-R; Zhou,-W-X; Zhang,-Y-X.
The behavioral, pathological and therapeutic features of the senescence-accelerated
mouse prone 8 strain as an Alzheimer's disease animal model.
2014 Jan;13:13-37.(sci IF=7.628) PDF 1-116.
4.ChenY1, Wang SX2, Mu R1, Luo X1, Liu ZS1, Liang B1, Zhuo HL3, Hao XP4, Wang
Q1, Fang DF1, Bai ZF1, Wang QY1, Wang HM5, Jin BF1, Gong WL1, Zhou T1, Zhang
XM1, Xia Q6, Li T7.
Dysregulation of the miR-324-5p-CUEDC2 axis leads to macrophage dysfunction
and is associated with colon cancer.
2014 Jun 26;7(6):1982-93.(sci IF=7.207) PDF 1-56.
5.Zhang G1, Wang K, Zheng B, Cheng M, Li Y, Liu K, Cai L.
Exchangeability of amino acid residues with similar physicochemical properties in
coiled-coil interactions.
2013 Dec 7;49(94):11086-8.(sci IF=6.718) PDF 1-131.
6. Yuan,-Y; Feng,-Y; Ren,-F; Niu,-S; Liu,-X; Che,-Y.
A botryane metabolite with a new hexacyclic skeleton from an entomogenous
fungus Hypocrea sp.
2013 Dec 6;15(23):6050-3. (sci IF=6.324) PDF 1-80.
7. Wang C1, Lu L, Na H, Li X, Wang Q, Jiang X, Xu X, Yu F, Zhang T, Li
J, Zhang Z, Zheng B, Liang G, Cai L, Jiang S, Liu K.
Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion
inhibitor: a promising strategy for discovering new antiviral therapeutics.
2014 Sep 11;57(17):7342-54.(sci IF=5,48) PDF 1-20.
8.Wang,-X-F;Guan,-F; Ohkoshi,-E; Guo,-W; Wang,-L; Zhu,-D-Q; Wang,-S-B;
Wang,-L-T; Hamel,-E; Yang,-D; Li,-L; Qian,-K; Morris-Natschke,-S-L; Yuan,-S;
Lee,-K-H; Xie,-L.
Optimization of 4-(N-cycloamino)phenylquinazolines as a novel class of
tubulin-polymerization inhibitors targeting the colchicine site.
2014 Feb 27;57(4):1390-402. (sci IF=5,48) PDF 1-81.
9. Wang C1, Shi W1, Cai L1, Lu L2, Yu F3, Wang Q2, Jiang X1, Xu X1, Wang
K1, Xu L1, Jiang S4, Liu K5.
Artificial peptides conjugated with cholesterol and pocket-specific small molecules
potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and
enfuvirtide-resistant HIV-1 strains.
2014 Jun;69(6):1537-45. (sci IF=5,439) PDF 1-75.
10. Wang C1, Shi W1, Cai L1, Lu L2, Yu F3, Wang Q2, Jiang X1, Xu X1, Wang
K1, Xu L1, Jiang S4, Liu K5.
Artificial peptides conjugated with cholesterol and pocket-specific small molecules
potently inhibit infection by laboratory-adapted and primary HIV-1 isolates and
enfuvirtide-resistant HIV-1 strains.
2014 Jun;69(6):1537-45. (sci IF=5,439) PDF 1-93 .
11. Zhang LM1, Qiu ZK1, Zhao N1, Chen HX1, Liu YQ1, Xu JP2, Zhang
YZ1, Yang RF3, Li YF1.
Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein
(18 kDa) in animal models of post-traumatic stress disorder.
2014 Oct;17(10):1659-69. (sci IF=5,264) PDF 1-64
12. Kong LL, Wang ZY, Han N, Zhuang XM, Wang ZZ, Li H1, Chen NH.
Neutralization of chemokine-like factor 1, a novel C-C chemokine, protects against
focal cerebral ischemia by inhibiting neutrophil infiltration via MAPK pathways in
rats.
2014 Jun 20;11:112. (sci IF=4.902) PDF 1-45
13. Song,-R; Bi,-G-H; Zhang,-H-Y; Yang,-R-F; Gardner,-E-L; Li,-J; Xi,-Z-X
Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and
relapse to drug-seeking behavior in rats
2014 Feb;77:398-405. (sci IF=4.89) PDF 1-129
14. Zhang LM1, Zhao N1, Guo WZ2, Jin ZL1, Qiu ZK3, Chen HX1, Xue
R1, Zhang YZ1, Yang RF4, Li YF5.
Antidepressant-like and anxiolytic-like effects of YL-IPA08, a potent ligand for the
translocator protein (18 kDa).
2014 Jun;81:116-25. (sci IF=4.819) PDF 1-77
15. Song,-R; Bi,-G-H; Zhang,-H-Y; Yang,-R-F; Gardner,-E-L; Li,-J; Xi,-Z-X
Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and
relapse to drug-seeking behavior in rats
2014 Feb;77:398-405. (sci IF=4.819) PDF 1-89
16. Zhang LM1, Zhao N1, Guo WZ2, Jin ZL1, Qiu ZK3, Chen HX1, Xue
R1, Zhang YZ1, Yang RF4, Li YF5
Antidepressant-like and anxiolytic-like effects of YL-IPA08, a potent ligand for
the translocator protein (18 kDa)
2014 Jun;81:116-25. (sci IF=4.819) PDF 1-100
17. Zhuang XM1, Wei X1, Tan Y1, Xiao WB1, Yang HY1, Xie JW1, Lu C2, Li H3.
Contribution of carboxylesterase and cytochrome P450 to the bioactivation and
detoxification of isocarbophos and its enantiomers in human liver microsomes.
2014 Jul;140(1):40-8. (sci IF=4.478) PDF 1-65
18. Yu G1, Zhang FQ2, Tang SE2, Lai MJ2, Su RB3, Gong ZH4.
Continuous infusion versus intermittent bolus dosing of morphine: A comparison
of analgesia, tolerance, and subsequent voluntary morphine intake
2014 Aug 23. (sci IF=4.092) PDF 1-14
19. Zhang LM1, Zhou WW, Ji YJ, Li Y, Zhao N, Chen HX, Xue R, Mei XG, Zhang
YZ, Wang HL, Li Y
Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder.
2014 Sep 18. (sci IF=3.988) PDF 1-11
20. Wang S1, Dong X2, Ma H3, Cui Y4, Tong J5
Purification, characterisation and protective effects of polysaccharides from alfalfa
on hepatocytes
2014 Nov 4;112:608-14. (sci IF=3.916) PDF 1-24
21. Xie X1, Zhou X1, Chen W1, Long L1, Li W1, Yang X2, Li S1, Wang L
L312, a novel PPARγ ligand with potent anti-diabetic activity by selective regulation
2014 Oct 11. (sci IF=3.829) PDF 1-5
22. Yang M1, He S2, Fan Y3, Wang Y1, Ge Z4, Shan L1, Gong W1, Huang
X2, Tong Y5, Gao C6.
Microenvironmental pH-modified solid dispersions to enhance the dissolution and
bioavailability of poorly water-soluble weakly basic GT0918, a developing
anti-prostate cancer drug: Preparation, characterization and evaluation in vivo.
2014 Aug 27;475(1-2):97-109.(sci IF=3.785) PDF 1-17
23. Yang M1, Xie S2, Li Q3, Wang Y1, Chang X4, Shan L1, Sun L4, Huang
X2, Gao C5.
Effects of polyvinylpyrrolidone both as a binder and pore-former on the release of
sparingly water-soluble topiramate from ethylcellulose coated pellets
2014 Apr 25;465(1-2):187-96. (sci IF=3.785) PDF 1-103
24. Li H1, Li F, Wu N, Su RB, Li J.
Methamphetamine induces dynamic changes of histone deacetylases in different
phases of behavioral sensitization.
2014 Sep;20(9):874-6. (sci IF=3.784) PDF 1-44
25. Yu,-G; Li,-S-H; Cui,-M-X; Yan,-L-D; Yong,-Z; Zhou,-P-L; Su,-R-B;
Gong,-Z-H
Multiple mechanisms underlying the long duration of action of thienorphine, a
novel partial opioid agonist for the treatment of addiction
2014 Mar;20(3):282-8. (sci IF=3.784) PDF 1-113
26. Zhang,-L; Zhao,-T-Y; Hou,-N; Teng,-Y; Cheng,-X; Wang,-B; Chen,-Y;
Jiang,-L; Wu,-N; Su,-R-B; Yang,-X; Li,-J
Generation and primary phenotypes of imidazoline receptor antisera-selected
(IRAS) knockout mice
2013 Dec;19(12):978-81. (sci IF=3.784) PDF 1-130
27. Wu Y1, Shi C2, Deng J1, Zhang X1, Song B1, Li L3
Expression and function of muscarinic subtype receptors in bladder interstitial cells
of cajal in rats
2014 Jul 8;11(3):1642-7. (sci IF=3.753) PDF 1-38
28. Yang,-C; Zhang,-T; Li,-Z; Xu,-L; Liu,-F; Ruan,-J; Liu,-K; Zhang,-Z
P-glycoprotein is responsible for the poor intestinal absorption and low toxicity of
oral aconitine: in vitro, in situ, in vivo and in silico studies
2013 Dec 15;273(3):561-8. (sci IF=3.63) PDF 1-82
29. Nie Z1, Zhang Y, Chen J, Lin Y, Wu B, Dong Y, Feng J, Liu Q, Xie J.
Monitoring urinary metabolites resulting from sulfur mustard exposure in rabbits,
using highly sensitive isotope-dilution gas chromatography-mass spectrometry.
2014 Aug;406(21):5203-12. (sci IF=3.63) PDF 1-82
30. Lin Y1, Chen J, Yan L, Guo L, Wu B, Li C, Feng J, Liu Q, Xie J.
Determination of nerve agent metabolites in human urine by isotope-dilution gas
chromatography-tandem mass spectrometry after solid phase supported
derivatization.
2014 Aug;406(21):5213-20. (sci IF=3.578) PDF 1-70
31. Ma X1, Tang J, Li C, Liu Q, Chen J, Li H, Guo L, Xie J.
Identification and quantification of ricin in biomedical samples by magnetic
immunocapture enrichment and liquid chromatography electrospray ionization
tandem mass spectrometry.
2014 Aug;406(21):5147-55. (sci IF=3.578) PDF 1-71
32. Meng H1, Jiang L2, Xu B1, Guo W3, Li J4, Zhu X4, Qi X5, Duan L5, Meng
X5, Fan Y2, Zhang C2.
Arabidopsis plastidial folylpolyglutamate synthetase is required for seed reserve
accumulation and seedling establishment in darkness.
2014 Jul 7;9(7):e101905. (sci IF=3.534) PDF 1-40
33. Chen,-W; Fan,-S; Xie,-X; Xue,-N; Jin,-X; Wang,-L
Novel PPAR pan agonist, ZBH ameliorates hyperlipidemia and insulin resistance
in high fat diet induced hyperlipidemic hamster
2014 Apr 23;9(4):e96056. (sci IF=3.534) PDF 1-98
34.Qiao,-S; Peng,-R; Yan,-H; Gao,-Y; Wang,-C; Wang,-S; Zou,-Y; Xu,-X; Zhao,-L;
Dong,-J; Su,-Z; Feng,-X; Wang,-L; Hu,-X
Reduction of phosphorylated synapsin I (ser-553) leads to spatial memory
impairment by attenuating GABA release after microwave exposure in Wistar rats.
2014 Apr 17;9(4):e95503. (sci IF=3.534) PDF 1-101
35. Yin,-J-Y; Wang,-H-M; Wang,-Q-J; Dong,-Y-S; Han,-G; Guan,-Y-B; Zhao,-K-Y;
Qu,-W-S; Yuan,-Y; Gao,-X-X; Jing,-S-F; Ding,-R-G
Subchronic toxicological study of two artemisinin derivatives in dogs
2014 Apr 16;9(4):e94034. (sci IF=3.534) PDF 1-102
36.Shi,-C;Boehme,-S; Bentley,-A-H; Hartmann,-E-K; Klein,-K-U; Bodenstein,-M;
Baumgardner,-J-E; David,-M; Ullrich,-R; Markstaller,-K
Assessment of regional ventilation distribution: comparison of vibration response
imaging (VRI) with electrical impedance tomography (EIT)
2014 Jan 27;9(1):e86638. (sci IF=3.534) PDF 1-119
37. Chen HX1, Jin ZL2, Zhang LM1, Xue R1, Xu XD1, Zhao N1, Qiu ZK1, Wang
XW3, Zhang YZ1, Yang RF4, Li YF1.
Antidepressant-like activity of YL-0919: a novel combined selective serotonin
reuptake inhibitor and 5-HT1A receptor agonist
2013 Dec 18;8(12):e83271. (sci IF=3.534) PDF 1-134
38. Dong Y1, Cui CB2, Li CW3, Hua W4, Wu CJ5, Zhu TJ6, Gu QQ7.
Activation of dormant secondary metabolite production by introducing neomycin
resistance into the deep-sea fungus, Aspergillus versicolor ZBY-3
2014 Jul 29;12(8):4326-52. (sci IF=3.512) PDF 1-32
39. Wu,-C-J; Li,-C-W; Cui,-C-B
Seven new and two known lipopeptides as well as five known polyketides: the
activated production of silent metabolites in a marine-derived fungus by chemical
mutagenesis strategy using diethyl sulphate
2014 12(4): 1815-38. (sci IF=3.512) PDF 1-104
40. Fang,-S-M; Wu,-C-J; Li,-C-W; Cui,-C-B
A practical strategy to discover new antitumor compounds by activating silent
metabolite production in fungi by diethyl sulphate mutagenesis
2014 Mar 27;12(4):1788-814. (sci IF=3.512) PDF 1-106
41. Xia,-M-W; Cui,-C-B; Li,-C-W; Wu,-C-J
Three new and eleven known unusual C25 steroids: activated production of silent
metabolites in a marine-derived fungus by chemical mutagenesis strategy using
diethyl sulphate.
2014 Mar 13;12(3):1545-68. (sci IF=3.512) PDF 1-111
42. Chen,-X-W; Li,-C-W; Cui,-C-B; Hua,-W; Zhu,-T-J; Gu,-Q-Q
Nine New and Five Known Polyketides Derived from a Deep Sea-Sourced
Aspergillus sp. 16-02-1
2014 May 27;12(6):3116-37. (sci IF=3.512) PDF 1-90
43. Lu M1, Wang B, Zhang C, Zhuang X, Yuan M, Wang H, Li W, Su R, Li J.
PQ-69, a novel and selective adenosine A1 receptor antagonist with inverse agonist
activity
2014 Sep 24. (sci IF=3.51) PDF 1-10
44. Xu L1, Jiang X1, Xu X1, Zheng B2, Chen X2, Zhang T1, Gao F1, Cai
L1, Cheng M3, Keliang Liu4.
The use of hairpin DNA duplexes as HIV-1 fusion inhibitors: synthesis,
characterization, and activity evaluation
2014 Jul 23;82:341-6. (sci IF=3.432) PDF 1-46
45.Li,-X; Lai,-K; Wu,-K; Huang,-D; Huang,-L.
Studies on the synthesis and biological evaluation of
the metabolite of clausenamide CM₂ and its stereoisomers.
Eur J Med Chem.2014 Mar 3,74: 736-41. ( SCI IF=3.432) PDF 1-114.
46.He,-Z; Chen,-Y; Dong,-H; Su,-R; Gong,-Z; Yan,-L.
Inhibition of vesicular glutamate transporters contributes to attenuate
methamphetamine-induced conditioned place preference in rats.
Behav Brain Res.2014 Jul,1; 267: 1-5. ( SCI IF=3.391) PDF 1-96.
47.Yong Z1, Yan L1, Gao X1, Gong Z1, Su R2.
Effects of thienorphine on synaptic structure and synaptophysin expression in the
rat nucleus accumbens.
Neuroscience.2014 Aug 22,;274:53-8. ( SCI IF=3.327) PDF 1-58.
48.Shen H, Zhu H, Song M, Tian Y, Huang Y, Zheng H, Cao R, Lin J, Bi
Z1, Zhong W.
A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa
heat shock protein HSP90AA1 and its client proteins in cancer cells.
BMC Cancer.2014 Aug 29, 14:629. ( SCI IF=3.319) PDF 1-135.
49.Zhang,-X; Li,-Y; Cheng,-J; Liu,-G; Qi,-C; Zhou,-W; Zhang,-Y.
Immune activities comparison of polysaccharide and polysaccharide-protein
complex from Lycium barbarum L.
Int J Biol Macromol.2014 Apr,65: 441-5 ( SCI IF=3.096) PDF 1-109.
50.Wu ZY1, Liu N, Qin B, Huang L, Yu F, Qian K, Morris-Natschke SL, Jiang
S, Chen CH, Lee KH, Xie L.
Optimization of the antiviral potency and lipophilicity of halogenated
2,6-diarylpyridinamines as a novel class of HIV-1 NNRTIS.
ChemMedChem.2014 Jul,9(7):1546-55. ( SCI IF=3.046) PDF 1-53.
51.Zhang H1, Gong W, Wang ZY, Yuan SJ, Xie XY, Yang YF, Yang Y, Wang
SS, Yang DX, Xuan ZX, Mei XG.
Preparation, characterization, and pharmacodynamics of thermosensitive
liposomes containing docetaxel.
J Pharm Sci. 2014 Jul,103(7):2177-83. ( SCI IF=3.007) PDF 1-60.
52.Li Z1, Liu Y2, Liu G1, Zhu J1, Zheng Z3, Zhou Y1, He J4.
Position-specific modification with imidazolyl group on10-23 DNAzyme realized
catalytic activity enhancement.
Bioorg Med Chem.2014 Aug,22(15):4010-7. ( SCI IF=2.951) PDF 1-43.
53.He,-X-Y; Lu,-L; Qiu,-J; Zou,-P; Yu,-F; Jiang,-X-K; Li,-L; Jiang,-S; Liu,-S;
Xie,-L.
Small molecule fusion inhibitors: design, synthesis and biological evaluation of
(Z)-3-(5-(3-benzyl-4-oxo-2-thioxothiazolidinylidene)methyl)-N-(3-carboxy-4-hydrox
y)phenyl-2,5-dimethylpyrroles and related derivatives targeting HIV-1 gp41.
Bioorg Med Chem. 2013 Dec 1,21(23): 7539-48. ( SCI IF=2.951) PDF 1-78.
54.Yu,-F-L; He,-X-Y; Gu,-C; Ohkoshi,-E; Wang,-L-T; Wang,-S-B; Lai,-C-Y; Yu,-L;
Morris-Natschke,-S-L; Lee,-K-H; Liu,-S; Xie,-L.
Discovery of novel antitumor dibenzocyclooctatetraene derivatives and related
biphenyls as potent inhibitors of NF-κB signaling pathway.
Bioorg Med Chem.2014 Jan 1,22(1): 325-33 ( SCI IF=2.951) PDF 1-87.
55.Zhang B1, He K2, Chen W1, Cheng X1, Cui H1, Zhong W1, Li S1, Wang L1.
Alagebrium (ALT-711) improves the anti-hypertensive efficacy of nifedipine in
diabetic-hypertensive rats.
Hypertens Res. 2014 Oct,37(10):901-7 ( SCI IF=2.936) PDF 1-42.
56.Zhang S1, Jin Y1, Liu X1, Yang L1, Ge Zj1, Wang H1, Li J2, Zheng J3.
Methamphetamine modulates glutamatergic synaptic transmission in rat primary
cultured hippocampal neurons.
Brain Res.2014 Sep 25,1582:1-11. ( SCI IF=2.828) PDF 1-29.
57.Xuan ZX1, Li LN1, Zhang Q1, Xu CW1, Yang DX1, Yuan Y2, An YH1, Wang
SS1, Li XW2, Yuan SJ.
Fully human VEGFR2 monoclonal antibody BC001 attenuates tumor angiogenesis
and inhibits tumor growth.
Int J Oncol.2014 Dec,45(6):2411-20. ( SCI IF=2.773) PDF 1-8.
58.Yang Y1, Yang Y, Xie X, Cai X, Mei X.
Preparation and characterization of photo-responsive cell-penetrating
peptide-mediated nanostructured lipid carrier.
J Drug Target.2014 Dec,22(10):891-900. ( SCI IF=2.723) PDF 1-34
59.Wang Q1, Bottalico L2, Mesaros C2, Blair IA.
Analysis of estrogens and androgens in postmenopausal serum and plasma by
liquid chromatography-mass spectrometry.
Steroids.2014 Aug 20, pii: S0039-128X(14)00205-0. ( SCI IF=2.716) PDF 1-22.
60.Zhang,-X-R; Qi,-C-H; Cheng,-J-P; Liu,-G; Huang,-L-J; Wang,-Z-F;
Zhou,-W-X; Zhang,-Y-X.
Lycium barbarum polysaccharide LBPF4-OL may be a new Toll-like receptor
4/MD2-MAPK signaling pathway activator and inducer.
Int Immunopharmacol.2014 Mar,19(1): 132-41. ( SCI IF=2.711) PDF 1-115.
60.Zhang,-X-R; Qi,-C-H; Cheng,-J-P; Liu,-G; Huang,-L-J; Wang,-Z-F;
Zhou,-W-X; Zhang,-Y-X.
Lycium barbarum polysaccharide LBPF4-OL may be a new Toll-like receptor
4/MD2-MAPK signaling pathway activator and inducer.
Int Immunopharmacol, 2014 Mar,19(1): 132-41. ( SCI IF=2.711) PDF 1-115.
61.Yao JF1, Zhou N2, Bai L3, Xu PX3, Liu KL2, Xue M4.
Simultaneous determination of five novel luteinizing hormone-releasing hormone
antagonists by LC-MS and pharmacokinetics in rats following cassette dosing.
J Chromatogr B Analyt Technol Biomed Life Sci,2014 Jul 1,962:94-101. ( SCI
IF=2.694) ) PDF 1-50.
62.Zhang Y1, Yue L1, Nie Z1, Chen J1, Guo L1, Wu B1, Feng J1, Liu Q2, Xie J3.
Simultaneous determination of four sulfur mustard-DNA adducts in rabbit urine
after dermal exposure by isotope-dilution liquid chromatography-tandem mass
spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Jun 15,961:29-35, ( SCI
IF=2.694) PDF 1-59.
63.Li,-X; Li,-Y; Wang,-J; Wang,-L; Zhong,-W; Ruan,-J; Zhang,-Z.
Quantification of peramivir in dog plasma by liquid chromatography/tandem mass
spectrometry employing precolumn derivatization.
J Chromatogr B Analyt Technol Biomed Life Sci,2014 Jan,1; 944: 1-5. ( SCI
IF=2.694) PDF 1-88.
64.Chen Y1, Song R1, Yang RF1, Wu N1, Li J2.
A novel dopamine D3 receptor antagonist YQA14 inhibits methamphetamine
self-administration and relapse to drug-seeking behaviour in rats.
Eur J Pharmacol, 2014 Sep 26, pii: S0014-2999(14)00678-5. ( SCI IF=2.684) PDF
1-9.
65.Hu D1, Wang Y2, Chen Z1, Ma Z2, You Q2, Zhang X2, Zhou T2, Xiao
Y2, Liang Q2, Tan H2, Xiao C2, Tang X2, Zhang B3, Gao Y4.
Artemisinin protects against dextran sulfate-sodium-induced inflammatory bowel
disease, which is associated with activation of the pregnane X receptor.
Eur J Pharmacol.2014 Sep 5,738:273-84, ( SCI IF=2.684) PDF 1-54.
66.Yong Z1, Gao X1, Ma W1, Dong H1, Gong Z1, Su R2.
Nalmefene reverses carfentanil-induced loss of righting reflex and respiratory
depression in rats.
Eur J Pharmacol. 2014 Sep 5,738:153-7. ( SCI IF=2.684) PDF 1-55.
67.Zhou P1, Li T2, Su R3, Gong Z4.
Effects of thienorphine on contraction of the guinea pig sphincter of Oddi,
choledochus and gall bladder.
Eur J Pharmacol. 2014 Aug 15,737:22-8. ( SCI IF=2.684) PDF 1-61.
68.Gu,-C; Yu,-F-L; Yu,-L; He,-X-Y; Zhong,-D; He,-L; Lv,-L; Xie,-L; Liu,-S
A novel synthetic dibenzocyclooctadiene lignan analog XLYF-104-6 attenuates
lipopolysaccharide-induced inflammatory response in RAW264.7 macrophage cells
and protects BALB/c mice from sepsis.
Eur J Pharmacol. 2014 Apr 15,729: 22-9. ( SCI IF=2.684) PDF 1-105.
69.Shen G1, Zhuang X2, Xiao W2, Kong L2, Tan Y1, Li H3.
Role of CYP3A in regulating hepatic clearance and hepatotoxicity of triptolide in
rat liver microsomes and sandwich-cultured hepatocytes.
Food Chem Toxicol.2014 Sep,71:90-6. ( SCI IF=2.61) PDF 1-51.
70.Xiao,-W; Zhuang,-X; Shen,-G; Zhong,-Y; Yuan,-M; Li,-H.
Simultaneous quantification of L-tetrahydropalmatine and its urine metabolites by
ultra high performance liquid chromatography with tandem mass spectrometry.
J Sep Sci.2014 Mar,37(6): 696-703. ( SCI IF=2.594) PDF 1-110
71.Yu G1, Lu XQ, Su RB, Gong ZH, Xie HZ, Hu HT, Hou XM.
Intravenous ilaprazole is more potent than oral ilaprazole against gastric lesions in
rats.
Dig Dis Sci. 2014 Oct,59(10):2417-22. ( SCI IF=2.55) PDF 1-62.
72.Zhang G, Li J, Wang T, Gao L, Quan D.
Oil-based formulation as a sustained-released injection for a novel synthetic peptide
Curr Pharm Biotechnol. 2014 Nov 10, ( SCI IF=2.511) PDF 1-3.
73.Sun,-Y-J; Chen,-Y; Pang,-C; Wu,-N; Li,-J
Acetazolamide attenuates chemical-stimulated but not thermal-stimulated acute
pain in mice.
Acta Pharmacol Sin. 2014 Jan, 35(1): 41-7. ( SCI IF=2.496) PDF 1-85.
74.Chang Y1, Zhou C1, Huang F2, Torous DK3, Luan Y4, Shi C5, Wang
H6, Wang X7, Wei N8, Xia Z9, Zhong Z10, Zhang M1, An F6, Cao Y4, Geng
X7, Jiang Y10,Ju Q8, Yu Y5, Zhu J9, Dertinger SD3, Li B7, Liao M5, Yuan
B9, Zhang T9, Yu J11, Zhang Z11, Wang Q12, Ma J1.
Inter-laboratory validation of the in-vivo flow cytometric micronucleus analysis
method (MicroFlow(®)) in China.
Mutat Res Genet Toxicol Environ Mutagen.2014 Sep,15;772:6-13. ( SCI IF=2.481)
PDF 1-4.
75.Yu H1, Yuan L2, Xu M3, Zhang Z4, Duan H5.
Sphingosine kinase 1 improves cutaneous wound healing in diabetic rats.
Injury. 2014 Jul,45(7):1054-8. ( SCI IF=2.462) PDF 1-68.
76.Liu H1, Zhao Z, Zhong Y, Shan Y, Sun X, Mao B, Cong Y.
Identification of a new Mpl-interacting protein, Atp5d.
Mol Cell Biochem. 2014 Jun,391(1-2):85-94. ( SCI IF=2.388) PDF 1-72.
77.Liu,-H; Zhao,-Z; Zhong,-Y; Shan,-Y; Sun,-X; Mao,-B; Cong,-Y
Identification of a new Mpl-interacting protein, Atp5d.
Mol Cell Biochem.2014 Jun,391(1-2): 85-94. ( SCI IF=2.388) PDF 1-95.
78.Yang XY1, Xu XQ1, Guan H2, Wang LL3, Wu Q4, Zhao GM5, Li S.
A new series of HAPs as anti-HBV agents targeting at capsid assembly.
Bioorg Med Chem Lett.2014 Sep 1,24(17):4247-9. ( SCI IF=2.331) PDF 1-25.
79.Wang LX1, Zhou XB1, Xiao ML1, Jiang N2, Liu F2, Zhou WX2, Wang
XK3, Zheng ZB4, Li S1.
Synthesis and biological evaluation of substituted
4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors.
Bioorg Med Chem Lett.2014 Aug 15,24(16):3739-43. ( SCI IF=2.331) PDF 1-31.
80.Liu N1, Qin B1, Sun LQ1, Yu F2, Lu L3, Jiang S2, Lee KH4, Xie L5.
Physicochemical property-driven optimization of diarylaniline compounds as potent
HIV-1 non-nucleoside reverse transcriptase inhibitors.
Bioorg Med Chem Lett. 2014 Aug 15,24(16):3719-23.. ( SCI IF=2.331) PDF 1-35.
81.Chen S1, Zhang Y2, Zhao C2, Ren F2, Liu X3, Che Y.
Hawaiinolides E-G, cytotoxic cassane and cleistanthane diterpenoids from the
entomogenous fungus Paraconiothyrium hawaiiense.
Fitoterapia. 2014 Oct 6, ( SCI IF=2.216) PDF 1-6.
82.Li C1, Yao ZH2, Qin ZF3, Zhang JB3, Cao RY4, Dai Y5, Yao XS6.
Isolation and identification of phase I metabolites of phillyrin in rats.
Fitoterapia. 2014 Sep,97:92-7. ( SCI IF=2.216) PDF 1-57.
83.Li R1, Chen S2, Niu S2, Guo L3, Yin J4, Che Y5.
Exserolides A-F, new isocoumarin derivatives from the plant endophytic fungus
Exserohilum sp.
Fitoterapia. 2014 Jul,96:88-94. ( SCI IF=2.216) PDF 1-66.
84.Zhang,-K; Ren,-J; Ge,-M; Li,-L; Guo,-L; Chen,-D; Che,-Y.
Mono- and bis-furanone derivatives from the endolichenic fungus Peziza sp.
Fitoterapia. 2014 Jan, 92: 79-84. ( SCI IF=2.216) PDF 1-123.
85.Gong,-W; Ma,-R; Mei,-D; Jing,-P; Dong,-X; Li,-B; Yang,-Y; Du,-L; Mei,-X-G;
Hu,-F-Q.
A novel subcutaneous infusion delivery system based on osmotic pump: in vitro
and in vivo evaluation.
Drug Deliv.2014 Feb,21(1): 1-7. ( SCI IF=2.202) PDF 1-83.
86.Yu G1, Yi S, Wang M, Yan H, Yan L, Su R, Gong Z.
The antinociceptive effects of intracerebroventricular administration of Chicago
sky blue 6B, a vesicular glutamate transporter inhibitor.
Behav Pharmacol.2013 Dec,24(8):653-8. ( SCI IF=2.194) PDF 1-132.
87.Zhuang XM1, Shen GL, Xiao WB, Tan Y, Lu C, Li H.
Assessment of the roles of P-glycoprotein and cytochrome P450 in
triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.
Drug Metab Dispos.2013 Dec,41(12):2158-65 ) PDF 1-133.
88.Liu F1, Zhuang X, Yang C, Li Z, Xiong S, Zhang Z, Li J, Lu C, Zhang Z.
Characterization of preclinical in vitro and in vivo ADME properties and prediction
of human PK using a physiologically based pharmacokinetic model for YQA-14, a
new dopamine D3 receptor antagonist candidate for treatment of drug addiction.
Biopharm Drug Dispos. 2014 Jul,35(5):296-307. ( SCI IF=2.178) PDF 1-69.
89.Wu CF1, Zhou W2, Suthisisang C3, Yang JY1.
Traditional medicine for treatment of neurodegenerative diseases.
Evid Based Complement Alternat Med.2014;2014:169821. ( SCI IF=2.175) PDF
1-28.
90.Zhang X, Wang Y, Liang Q, Ma Z, Xiao C, Tan H, Gao Y.
The Correlation between Chemical Composition, as Determined by UPLC-TOF-MS,
and Acute Toxicity of Veratrum nigrum L. and Radix paeoniae alba.
Evid Based Complement Alternat Med.2014,2014:892797. ( SCI IF=2.175) PDF
1-37.
91.Huang,-Y; Hu,-Z-Y; Yuan,-H; Shu,-L; Liu,-G; Qiao,-S-Y; Sun,-L; Zhou,-W-X;
Zhang,-Y-X.
Danggui-Shaoyao-San Improves Learning and Memory in Female SAMP8 via
Modulation of Estradiol.
Evid Based Complement Alternat Med.2014,2014:327294 .( SCI IF=2.175) PDF
1-99.
92.Zhang G1, Li J, Gao L, Wang T, Quan D.
Morphology of nanostructures and their long-acting properties in vivo for a novel
synthetic peptide of gonadotropin-releasing hormone antagonist.
J Pharm Pharmacol.2014 Aug ,66(8):1077-81. ( SCI IF=2.161) PDF 1-74.
93.He YY1, Liu CL, Li X, Zhong W, Li S, He KL, Wang LL.
Effects of PP1-12, a novel protein phosphatase-1 inhibitor, on ventricular function
and remodeling after myocardial infarction in rats.
J Cardiovasc Pharmacol. 2014 Oct,64(4):360-7. ( SCI IF=2.111) PDF 1-7.
94.Liu XT1, Wang ZX1, Yang Y2, Wang L2, Sun RF2, Zhao YM2, Yu NJ3.
Active components with inhibitory activities on IFN-γ/STAT1 and IL-6/STAT3
signaling pathways from Caulis Trachelospermi.
Molecules.2014 Aug 5,19(8):11560-71. ( SCI IF=2.095) PDF 1-26.
95.Cao S1, Zhou X2, Yang Y3, Zhong W4, Sun T5.
Selective substitution of 31/42-OH in rapamycin guided by an in situ IR technique
Molecules.2014 Jun 10,19(6):7770-84 ( SCI IF=2.095) PDF 1-49.
96.Xu,-L; Zhang,-Y; Dai,-W; Wang,-Y; Jiang,-D; Wang,-L; Xiao,-J; Yang,-X;
Li,-S.
Design, synthesis and SAR study of novel trisubstituted pyrimidine amide
derivatives as CCR4 antagonists.
Molecules.2014, 19(3): 3539-51. ( SCI IF=2.095) PDF 1-108.
97.Li,-X; Zhou,-X; Zhang,-J; Wang,-L; Long,-L; Zheng,-Z; Li,-S; Zhong,-W.
Synthesis and biological evaluation of Chromenylurea and Chromanylurea
derivatives as anti-TNF-alpha agents that target the p38 MAPK pathway.
Molecules.2014 Feb 13,19(2): 2004-28. ( SCI IF=2.095) PDF 1-117.
98.Qin JJ1, Chen HX2, Zhao N2, Yuan L2, Zhang YZ2, Yang RF3, Zhang LM4, Li
YF5.
The role of activation of the 5-HT1A receptor and adenylate cyclase in the
antidepressant-like effect of YL-0919, a dual 5-HT1A agonist and selective
serotonin reuptake inhibitor.
Neurosci Lett.2014 Oct ,17;582:104-8. ( SCI IF=2.055) PDF 1-12.
99.Zhang LM1, Wang HL2, Zhao N1, Chen HX1, Li YF3, Zhang YZ4.
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of
the total flavonoids extracted from Xiaobuxin-Tang.
Neurosci Lett.2014 Jul 11,575:31-6. ( SCI IF=2.055) PDF 1-63.
100.Chen WQ1, Zhang YZ2, Yuan L1, Li YF1, Li J3.
Neurobehavioral evaluation of adolescent male rats following repeated exposure to
chlorpyrifos.
Neurosci Lett. 2014 Jun, 6;570:76-80. ( SCI IF=2.055) PDF 1-67.
101.Chen,-W-Q; Zhang,-Y-Z; Yuan,-L; Li,-Y-F; Li,-J.
Neurobehavioral evaluation of adolescent male rats following repeated exposure to
chlorpyrifos.
Neurosci Lett. 2014 Jun 6; 570: 76-80. ( SCI IF=2.055) PDF 1-94.
102.Song,-D; Zhu,-S; Li,-X; Zheng,-G.
Homology modeling and docking studies of BjGL, a novel (+) gamma-lactamase
from Bradyrhizobium japonicum.
J Mol Graph Model. 2014 Feb,47: 1-7 ( SCI IF=2.022) PDF 1-86.
103.Wei L1, Ji Y, Gong W, Kang Z, Meng M, Zheng A, Zhang X, Sun J.
Preparation, physical characterization and pharmacokinetic study of paclitaxel
nanocrystals.
Drug Dev Ind Pharm.2014 Aug, 26:1-10 ( SCI IF=2.006) PDF 1-21.
104.Wang Y1, Yang J, Qian Y, Yang M, Qiu Y, Huang W, Shan L, Gao C.
Novel ethylcellulose-coated pellets for controlled release of metoprolol succinate
without lag phase: characterization, optimization and in vivo evaluation.
Drug Dev Ind Pharm.2014 Jul , 1:1-10. ( SCI IF=2.006) PDF 1-41.
105.Shan,-J; Sun,-G; Ren,-J; Zhu,-T; Jia,-P; Qu,-W; Li,-Q; Wu,-J; Ma,-H;
Wen,-S; Wang,-Y.
An alpha-glucan isolated from root of Isatis Indigotica, its structure and adjuvant
activity.
Glycoconj J.2014 May,31(4): 317-26. ( SCI IF=1.948) PDF 1-92.
106.Liu,-C-L; He,-Y-Y; Li,-X; Li,-R-J; He,-K-L; Wang,-L-L.
Inhibition of serine/threonine protein phosphatase PP1 protects cardiomyocytes
from tunicamycin-induced apoptosis and I/R through the upregulation of
p-eIF2alpha
Int J Mol Med. 2014 Mar,33(3): 499-506. ( SCI IF=1.88) PDF 1-122.
107.Li H1, Tan Y, Yang L, Gao L, Wang T, Yang X, Quan D.
Dissolution evaluation in vitro and bioavailability in vivo of self-microemulsifying
drug delivery systems for pH-sensitive drug loratadine.
J Microencapsul.2014 Nov,21:1-6. ( SCI IF=1.878) PDF 1-1.
108.Zhou N1, Gao X, Lv Y, Cheng J, Zhou W, Liu K.
Self-assembled nanostructures of long-acting GnRH analogs modified at position 7.
J Pept Sci. 2014 Nov,20(11):868-75. ( SCI IF=1.862) PDF 1-33.
109.Meng,-Q; Kou,-Y; Ma,-X; Guo,-L; Liu,-K.
Nanostructures from the self-assembly of alpha-helical peptide amphiphiles.
J Pept Sci.2014 Mar,20(3): 223-8. ( SCI IF=1.862) PDF 1-118.
110.Lai,-Y; Xiang,-M; Liu,-S; Li,-E; Che,-Y; Liu,-X.
A novel high-throughput nematicidal assay using embryo cells and larvae of
Caenorhabditis elegans.
Exp Parasitol. 2014 Apr, 139: 33-41. ( SCI IF=1.859) PDF 1-79.
111.Gao X, Ma W, Dong H, Yong Z, Su R.
Establishing a rapid animal model of osteoporosis with ovariectomy plus low
calcium diet in rats.
Int J Clin Exp Pathol.2014 Jul 15,7(8):5123-8. ( SCI IF=1.783) PDF 1-13.
112.Wang Y1, Dai J, Chang X, Yang M, Shen R, Shan L, Qian Y, Gao C.
Model Drug as Pore Former for Controlled Release of Water-Soluble Metoprolol
Succinate from Ethylcellulose-Coated Pellets Without Lag Phase: Opportunities
and Challenges.
AAPS PharmSciTech.2014 Aug 28, ( SCI IF=1.776) PDF 1-18.
113.Wang Y1, Dai J, Chang X, Yang M, Shen R, Shan L, Qian Y, Gao C.
Model Drug as Pore Former for Controlled Release of Water-Soluble Metoprolol
Succinate from Ethylcellulose-Coated Pellets Without Lag Phase: Opportunities
and Challenges.
AAPS PharmSciTech.2014 Aug 28. ( SCI IF=1.776) PDF 1-19.
114.Liao S1, Fan SY, Liu Q, Li CK, Chen J, Li JL, Zhang ZW, Zhang ZQ, Zhong
BH, Xie JW.
In vitro evaluation of 9-(2-phosphonylmethoxyethyl)adenine ester analogues, a
series of anti-HBV structures with improved plasma stability and liver release.
Arch Pharm Res. 2014 Nov,37(11):1416-25. ( SCI IF=1.751) PDF1-76.
115.Wang D1, Meng F, Yu L, Sun L, Sun L, Guo J.
A sensitive LC-MS/MS method for quantifying capsaicin and dihydrocapsaicin in
rabbit plasma and tissue: application to a pharmacokinetic study.
Biomed Chromatogr. 2014 Aug 4, ( SCI IF=1.662) PDF 1-30.
116.Hua,-L; Gao,-X; Yang,-X; Wan,-D; He,-C; Cao,-J; Song,-H.
Highly efficient production of peptides: N-glycosidase F for N-glycomics analysis.
Protein Expr Purif.2014 May, 97: 17-22. ( SCI IF=1.508) PDF 1-107.
117.Gao,-L; Xie,-H; Dong,-L; Zou,-J; Fu,-J; Gao,-X; Ou,-L; Xiang,-S; Song,-H.
Gankyrin is essential for hypoxia enhanced metastatic potential in breast cancer
cells
Mol Med Rep.2014 Mar,9(3): 1032-6. ( SCI IF=1.484) PDF 1-120.
118.Wang T1, Lin W2, Dai X2, Gao L1, Wang B2, Quan D3.
Determination of Iodate by HPLC-UV after On-Line Electrochemical Reduction to
Iodide.
J Chromatogr Sci.2014 Jul 6,pii: bmu053. ( SCI IF=1.026) PDF 1-39.
119.Ying C1, Ning W1, Ying L1, Hao G2, Hua-Jin D1, Rui-Bin S1, Xin-Sheng
Y2, Jin L.
Anti-nociceptive and anti-inflammatory activities of the extracts of Stauntonia
chinensis.
Pak J Pharm Sci.2014 Sep,27(5):1317-25. ( SCI IF=0.95) PDF 1-15.
120.Ying C1, Ning W1, Ying L1, Hao G2, Hua-Jin D1, Rui-Bin S1, Xin-Sheng
Y2, Jin L1.
Anti-nociceptive and anti-inflammatory activities of the extracts of Stauntonia
chinensis.
Pak J Pharm Sci. 2014 Sep,27(5):1317-25. ( SCI IF=0.95) PDF 1-16.
121.Dong,-N; Li,-Z; Li,-Q; Wu,-J; Jia,-P; Wang,-Y; Gao,-Z; Han,-G; Wu,-Y;
Zhou,-J; Shan,-J; Li,-H; Wei,-W.
Absorption, distribution and pathological injury in mice due to ricin poisoning via
the alimentary pathway.
J Toxicol Pathol.2014 Apr, 27(1): 73-80. ( SCI IF=0.943) PDF 1-97.
122.Wang K1, Li PF, Du L, Liu C, Hu M, Lian SJ, Liu YX.
Protective Effects of Kojic Acid on the Periphery Blood and Survival of Beagle
Dogs after Exposure to a Lethal Dose of Gamma Radiation.
Radiat Res. 2014 Nov 19. PDF 1-2.
123.Kong LL1, Wang ZY2, Hu JF3, Yuan YH3, Han N3, Li H4, Chen NH5.
Inhibition of chemokine-like factor 1 protects against focal cerebral ischemia
through the promotion of energy metabolism and anti-apoptotic effect.
Neurochem Int. 2014 Oct,76:91-8. PDF 1-36.
124.Jin ZL1, Gao N1, Zhang JR2, Li XR1, Chen HX3, Xiong J1, Li YF3, Tang Y4.
The discovery of Yuanzhi-1, a triterpenoid saponin derived from the traditional
Chinese medicine, has antidepressant-like activity.
Prog Neuropsychopharmacol Biol Psychiatry.2014 Aug ,53:9-14. PDF 1-73.
125.Liu,-Q; Zhang,-J; Zhang,-X; Yang,-X; Hua,-L; Gao,-X; Fu,-J; Song,-H.
Construction and identification of a full-length human secretory antibody library in
Pichia pastoris.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi.2014 Jan,30(1): 58-62. PDF 1-84.
126.Xiao,-Z; Li,-L; Li,-Y; Zhou,-W; Cheng,-J; Liu,-F; Zheng,-P; Zhang,-Y; Che,-Y
Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic
tumor cell death in nude mice.
Cell Death Dis.2014 May 22,5:e1241. PDF 1-91.
127.Yu,-G; Yan,-H; Gong,-Z-H
Effects of acute and repeated morphine treatment on
κ-opioid receptor protein levels in mesocorticolimbicsystem.
J Recept Signal Transduct Res.2014 Feb,34(1): 44-7. PDF 1-121.
128.Liu,-Q; Zhang,-J; Zhang,-X; Yang,-X; Hua,-L; Gao,-X; Fu,-J; Song,-H
Construction and identification of a full-length human secretory antibody library in
Pichia pastoris.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi.2014 Jan,30(1): 58-62. PDF 1-125.