List of NHMRC Grant Recipients – August 2014 Round Chief Investigator A Grant Type Project Title Total Grant Awarded Dr Allan McRae Career Development Fellowships Career Development Fellowships Genetics of DNA Methylation and Its Role in Disease Susecptibility An Integrated Genomic and Epigenomic Approach to Dissect the Aetiology of Motor Neuron Disease The genetic and cellular control of lymphangiogenesis in health and disease How Sweet It Is: diagnostic clinical and experimental glycoproteomics Reducing prolonged sitting time in adults $411,768 Microfluidic Strategy for Circulating Tumour Cells Analysis in Cancer Patients Bacterial Pathogenomics: whole-genome sequencing to investigate infection transmission, pathogenesis and antibiotic resistance Chronic Kidney Disease Centre of Research Excellence Improving translation of intensity and quality of upper limb rehabilitation provided by occupational therapists to children with unilateral cerebral palsy: A cluster randomised controlled trial Glucose transport in the diabetic kidney $411,768 Methamphetamine clandestine laboratories: An analysis of the geo-spatial dynamics between ecological factors, pharmacists, pseudorunners and related health harms. $309,436 Dr Beben Benyamin Dr Benjamin Hogan Career Development Fellowships Dr Benjamin Schulz Career Development Fellowships Career Development Fellowships Career Development Fellowships Career Development Fellowships Dr Genevieve Healy Dr Muhammad Shiddiky Dr Scott Beatson Prof Wendy Hoy Dr Leanne Sakzewski Dr Linda Gallo Mr Jason Ferris Centre for Research Excellence Early Career Fellowships (Australia) Early Career Fellowships (Australia) Early Career Fellowships (Australia) $411,768 $455,452 $455,452 $411,768 $455,452 $2,496,981 $216,605 $309,436 Mr Robert Power Early Career Fellowships (Australia) Dr Anthony Raphael Early Career Fellowships (Overseas) Early Career Fellowships (Overseas) Dr Timothy Kidd Dr William Harrison Early Career Fellowships (Overseas) Mr Mitchell Sullivan Early Career Fellowships (Overseas) NHMRC Infrastructure Grants NHMRC Project Grants Research Admin Officer A/Pr Abdullah Mamun A/Pr Andreas Schibler NHMRC Project Grants A/Pr Gerhard Schenk NHMRC Project Grants NHMRC Project Grants A/Pr Greig De Zubicaray A/Pr Jennifer Fleming NHMRC Project Grants A/Pr Kay Crossley NHMRC Project Grants A/Pr Kiarash Khosrotehrani NHMRC Project Grants A/Pr Kristen Radford NHMRC Project Grants Understanding the genetic architecture of psychiatric disorders in patients and populations Modulating the skin immune system with physical stimulus Transcriptome Characterization of Klebsiella pneumoniae during Infection (TRACKIN) Novel approaches to understanding peripheral vision in patients with central vision loss Exploring the Role of Glycogen Structure in Type 2 Diabetes. 2014 Equipment Grant $309,436 Generational and developmental pathways of childhood and adolescent obesity: A three generation cohort study High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial An integrated approach to combat antibiotic resistance A prospective study of language impairment and recovery following surgery for brain tumours Efficacy of prospective memory rehabilitation plus metacognitive skills training for adults with traumatic brain injury: a randomised controlled trial Femoroacetabular impingement and early arthritis Role of resident endothelial progenitor cells in melanoma vascularisation and progression A new approach to the design and evaluation of T $1,232,041 $393,276 $348,252 $371,844 $374,986 $524,104 $1,242,929 $377,077 $823,663 $461,398 $896,918 $922,589 $382,077 A/Pr Luke Guddat NHMRC Project Grants A/Pr Marcus Meinzer NHMRC Project Grants A/Pr Nikolas Haass NHMRC Project Grants A/Pr Philip Stevenson NHMRC Project Grants NHMRC Project Grants A/Pr Richard Sturm A/Pr Ross Cunnington NHMRC Project Grants A/Pr Thomas Burne NHMRC Project Grants A/Pr Trent Woodruff NHMRC Project Grants A/Pr Trent Woodruff NHMRC Project Grants Dr Andrew Brooks NHMRC Project Grants Dr Beben Benyamin NHMRC Project Grants Dr Benjamin Hogan NHMRC Project Grants Dr Benjamin Hogan NHMRC Project Grants cell vaccines for cancer and infectious disease. Acetohydroxyacid synthase: A new drug target for human fungal pathogens Neural mechanisms of language facilitation in aphasia due to transcranial direct current stimulation. Defining the role of Microphthalmia-associated Transcription Factor (MITF) in melanoma heterogeneity by real-time cell cycle imaging Protection against Herpesvirus super-infection Investigation of the molecular basis of human nevogenesis and melanoma initiation High-resolution brain imaging of basal ganglia function Does adult vitamin D deficiency increase vulnerability to social stress resulting in altered brain function? Complement activation as a therapeutic target and clinical biomarker for Parkinson's disease Determining the contribution of peripheral immune complement signalling in the progression of motor neuron disease A New Paradigm for Class I Cytokine Receptor Activation Novel epidemiological methods to infer the causal effects of risk factors on neuropsychiatric and cardiovascular disorders A critical new signaling axis in lymphatic vascular angiogenesis Novel transcription factor regulation of lymphatic $520,106 $502,131 $594,492 $589,492 $579,492 $570,364 $319,776 $482,492 $958,723 $919,835 $358,957 $678,846 $800,084 Dr Christina Schroeder NHMRC Project Grants Dr Enzo Porrello NHMRC Project Grants Dr Enzo Porrello NHMRC Project Grants Dr Ingrid Winkler NHMRC Project Grants Dr Joseph Powell NHMRC Project Grants Dr Martin Sale NHMRC Project Grants Dr Paul Dawson NHMRC Project Grants Dr Peter Simpson NHMRC Project Grants Dr Roberta Mazzieri NHMRC Project Grants Dr Sang Hong Lee NHMRC Project Grants Dr Stella Bjorkman NHMRC Project Grants Dr Stuart Mazzone NHMRC Project Grants Prof Alastair McEwan NHMRC Project Grants Prof Andrew Perkins NHMRC Project vascular angiogenesis in health and disease Understanding how toxins interact with lipid membranes and ion channels Regulation of endogenous heart regeneration by an anti-fibrotic microRNA. Regulation of heart development and regeneration by DNA methylation. Haematopoietic Stem Cell glycome regulates outcome of niche interactions Determining shared genetic control of RNA transcription across 45 human tissue types Mimicking slow wave sleep to enhance plasticity in the elderly human brain Neuroprotective role of sulphate among preterm babies (SuPreme study) Defining the genomic and therapeutic landscape of familial breast cancer Genetic engineering of tumor-infiltrating monocytes to inhibit primary and metastatic breast cancer Advanced whole-genome approaches for causative variant detection and individual risk prediction of complex traits in human populations. Carbon dioxide as a treatment for seizures in the newborn Dissecting the central organisation of cough neural networks Zinc as an antimicrobial agent and its effect on the pathogenesis of Group A Streptococcus KLF circuitry in health and $579,492 $427,077 $535,616 $878,872 $256,398 $415,106 $720,437 $1,114,997 $760,334 $343,961 $850,890 $846,670 $341,398 $684,453 Prof David Craik Grants NHMRC Project Grants Prof David Craik NHMRC Project Grants Prof David Evans NHMRC Project Grants Prof David Evans NHMRC Project Grants Prof David Fairlie NHMRC Project Grants Prof David Fairlie NHMRC Project Grants Prof Geoffrey Goodhill NHMRC Project Grants Prof Gerald Holtmann NHMRC Project Grants Prof Gregory Monteith NHMRC Project Grants Prof Gregory Monteith NHMRC Project Grants Prof Jennifer Martin NHMRC Project Grants Prof John Upham NHMRC Project Grants Prof Joseph Lynch NHMRC Project disease Development of selective melanocortin receptor agonists and antagonists Development of peptidebased scaffolds for intracellular cancer targets Novel ways of utilizing genome-wide DNA methylation data from peripheral blood samples in genetic epidemiology Gene expression profiling in critically ill patients with septic shock: The ADRENALGEPS Study Downsizing A Human Protein To Modulate Inflammatory Diseases Targeting Protease Activated Receptor 2 In Immunometabolism And Obesity Computational analysis of the influence of growth cone shape dynamics on axon guidance Pathophysiology of functional dyspepsia: Integration of upper gut function, inflammation and a systems biology approach. Exploiting the overexpression of a specific calcium permeable ion channel in breast cancer cells: a new pharmacological approach to targeting breast cancer. Resistance to Herceptin (trastuzumab) in HER2 positive breast cancers: the role of calcium signalling. Unraveling the dynamic Munc18a:Syntaxin1 interaction required for neurotransmission Using influenza vaccination to understand and improve anti-viral immunity in COPD Using artificial synapses to $663,592 $1,418,103 $276,398 $834,270 $500,616 $698,475 $335,492 $719,480 $559,492 $599,492 $653,472 $1,266,560 $498,009 Grants Prof Martin Lavin NHMRC Project Grants Prof Matthew Cooper NHMRC Project Grants Prof Michael McGuckin NHMRC Project Grants Prof Michael Stowasser NHMRC Project Grants Prof Naomi Wray NHMRC Project Grants Prof Naomi Wray NHMRC Project Grants Prof Paul Colditz NHMRC Project Grants NHMRC Project Grants Prof Peter Sly Prof Ranjeny Thomas NHMRC Project Grants Prof Rodney Minchin NHMRC Project Grants Prof Roslyn Boyd NHMRC Project Grants Prof Stephen Williams NHMRC Project Grants Prof Walter Thomas NHMRC Project Grants investigate the functional pathology underlying epilepsy To investigate the role of ATM protein in protecting against neurodegeneration Inhibitors of NLRP3 activation for treatment of inflammatory CNS diseases IL-22 as a Suppressor of Pancreatic ß-Cell Stress and a Treatment for Diabetes A novel approach to streamlining the diagnosis of primary aldosteronism Gene discovery in motor neuron disease through systems genomics Multivariate whole genome estimation and prediction analysis of genomics data applied to psychiatric disorders Neurodevelopment of the preterm infant Immune recognition of upper airway microbiota in early life as a determinant of respiratory health in children Understanding the development of autoimmunity in response to citrullinated peptide antigen presentation to T cells in rheumatoid arthritis Role of sirtuins in the regulation of the carcinogen metabolising arylamine Nacetyltransferases REACH: Randomised trial of EArly Rehabilitation in Congenital Hemiplegia Role of dendritic information processing in visual circuit computations New mediators of GPCRgrowth factor receptor transactivation $920,798 $991,062 $822,656 $263,133 $918,784 $610,529 $1,645,141 $1,088,362 $1,132,540 $317,077 $939,039 $861,300 $588,813