HOFSTRA UNIVERSITY
ENGG 81/BIO 81 - Introduction to Bioengineering
Wed 8:00-8:55 &
Mon, Wed 9:05-10:00; Weed 100A
Dr. Sina Y. Rabbany
110 Weed Hall, Ext. 6672
Email: Sina.Y.Rabbany@hofstra.edu
Spring 2013
Office Hours: Wed: 11:00-12:00
Course Description: A survey of applications of the quantitative methods in
engineering and physical science to problems in biology and medicine. Biological
systems are examined in order to foster strategic insights into the design and
development of artificial substitutes. Topics include: biomechanics, including solids and
fluids, biotransport in the lung and circulatory system, stimulation response in sensory
systems, biomaterials of surgical implants, biocontrol, and bioinstrumentation. Oral
presentations in class and a written report on a biomedical design project are required.
Web exploration on topics relevant to lectures are required. Additional references will
be assigned in class as they are needed. STUDENTS ARE RESPONSIBLE FOR THE
SCOPE OF MATERIAL AS COVERED IN CLASS.
Text:
Introduction to Biomedical Engineering
M. C. Domach, 2nd Edition Prentice Hall, 2010
References: Life, 4th Edition,
Ricki Lewis, McGraw-Hill Higher Education, 2002
Physics in Biology and Medicine, 2nd Edition
Paul Davidovits, Academic Press, 2001
Biology, 6th Edition
Peter Raven and George Johnson, McGraw Hill, 2002
Grading Policy:
Quizzes + Class Participation
Design Projects
Midterm
Final Examination
15%
15%
30%
40%
Lectures and class discussions will complement readings and attendance is encouraged in
the strongest possible sense. Students are responsible for the scope of material as covered
in class.
All examinations are in class, closed book and Mandatory.
exceptions.
No excuses, no
Course Objectives
1. The students will be able to determine the applications of the quantitative
methods of the engineering and physical science to problems in biology and
medicine
Evaluation: HW and/or Exam
2. The students will be able to determine the role of feedback in physiological
systems.
Evaluation: HW and/or Exam
3. The students will be able to learn organ functions and be able to examine the
incorporation of design in physiological systems.
Evaluation: HW and/or Exam
4. The students will be able to apply molecular binding phenomena to a variety of
practical bioengineering situations.
Evaluation: HW and/or Exam
5. The students will be able to learn stem cell biology and tissue engineering.
Evaluation: Design Project and Exam
6. The students will be able to learn and apply biocompatibility issues in
engineering design.
Evaluation: HW and/or Exam
ABET Program Objectives
e) an ability to identify, formulate, and solve engineering problems
j) a knowledge of contemporary issues
ENGG 81/BIO 81 - INTRODUCTION TO BIOENGINEERING
Course Outline
Date
Lecture Topic/Reading
Home Work
Assigned/Due
Mon. 1/28
Introduction & Scope: What is Bioengineering? (Domach, Ch. 0)
#1
Building blocks of Living Systems (Domach, Ch. 1)
Wed. 1/30
System Principles of Living Systems (Domach, Ch. 2)
Mon. 2/4
Functional and Coordinated Systems (Domach, Ch. 3)
Wed. 2/6
Role of Feedback in Physiological Systems
Mon. 2/11
Bioenergetics (Domach, Ch. 4)
Wed. 2/13
Organs and Functions (Domach, Ch. 9)
Mon. 2/18
#1
#3
#2
#4
#3
#5
#4
#6
#5
#7
#6
#8
#7
#9
#8
#10
#9
NO CLASS – President’s Day
Wed. 2/20
Heart & Circulatory System
Mon. 2/25
The Human Respiratory System and Gas Transport
Wed. 2/27
The Musculoskeletal System; Biomechanics
Mon. 3/4
The Human Nervous System
Wed. 3/6
Biofluid Mechanics (Domach, Ch. 11)
Mon. 3/11
Role of Flow Mechanics in Vascular Cell Biology
Wed. 3/13
MIDTERM EXAMINATION
Mon. 3/18
Cardiac Mechanics (Pressure Volume Loops)
Wed. 3/20
Stem Cells: Adult vs. Embryonic
Mon. 325-
#2
NO CLASS – Spring Recess
Mon. 4/1
Wed. 4/3
Stem Cell Therapy
Mon. 4/8
Blood Composition and RBC Design
Wed. 4/10
Molecular Basis of Catalysis and Regulation (Domach, Ch. 5)
Mon. 4/15
Analysis of Molecular Binding Phenomena (Domach, Ch. 6)
Wed. 4/17
Design in Biomolecular Technology (Domach, Ch.7)
Mon.4/22
Metabolic and Tissue Engineering (Domach. Ch.8)
Wed. 4/24
Biomaterials (Domach, Ch. 12), Biological Materials
Mon. 4/29
Biocompatibility issues in Engineering Design
Wed. 5/1
Design and Development of Artificial Blood
Mon. 5/6
Student Design Presentations
Wed. 5/8
Concluding Remarks and Final Review
FINAL EXAMINATION
#11
#12
#10
#11
#12