INFECTION & IMMUNITY WORKSHOP, 5th DECEMBER 2010 Theme: Host / Pathogen Interactions Venue: Meeting Room 2, Perth Convention Centre Session I: Host responses to bacterial and extracellular pathogens 8:45 AM - 10:20 AM Chair: Lea-Ann Kirkham 8:45am 8:50am 9:10am 9:30am 9:50am 10:05am Andrew Currie - Welcome Odilia Wijburg (Uni Melb: 20 min) “The polymeric Ig receptor and mucosal immunity: more than protection against infection” Gary Lee (UWA: 20 min) “Pleural Infection – a centuries-old and neglected disease” Selma Wiertsema (UWA: 20 min) “Protection against bacterial infection in children with recurrent ear disease” Sandeep Gupta (AgResearch: 15 min) “Immunostimulatory effects of RNase 4 and RNase5 on the recognition of bacterial DNA in mouse macrophages” Joanna Kirman (Malaghan Institute of Medical Research: 15 min) “Memories are made of this: memory CD4+ T cell subsets that protect against mycobacterial infection” Morning Tea 10:20 AM - 10:45 Session II: Host responses to viral and intracellular pathogens 10:45 AM - 12:35 PM Chair: Allison Imrie 10:45am 11:15am 11:35am 11:50am 12:05pm 12:20pm Antonio Bertoletti (Singapore Institute for Clinical Sciences; 30 min) “Restoring anti-viral immunity in chronic HBV infection” Martyn French (UWA: 20 min) “Immune restoration disease in HIV patients responding to antiretroviral therapy: another dark side of the immune system” Alec Redwood (UWA: 15 min) “Natural killer cells drive within-host competition between co-infecting strains of murine cytomegalovirus” Frank Griffin (Uni of Otago: 15 min) “Gene markers for resistance and susceptibility to pathogenic mycobacteria: a deer model” Erin Lousberg (Hanson Institute SA: 15 min) “Innate immune recognition of recombinant fowlpox virus by TLR7 and TLR9 does not contribute to MyD88-mediated and IL-18 -dependent antigen-specific adaptive immune responses” Antje Blumenthal (Uni of Queensland: 15 min) “RP105 facilitates macrophage activation by mycobacterial lipoproteins and viable Mycobacterium tuberculosis” Lunch 12:35 PM - 1:30 PM Session III: Joint Session with Mucosal Immunology Workshop 1:30 PM - 2:30 PM Chairs: Andrew Currie 1:30pm Phil Sutton (Uni of Melbourne: 30 min) “A novel mechanism of host regulation of bacterial-driven gut inflammation” 2:00pm Andrew Luster (Massachusetts General Hospital: 30 min) “Chemokine Control of Effector and Regulatory T cell Trafficking into the Lung” Afternoon Tea 2:30 PM – 2:55 PM Session IV: Emerging, Regional and Tropical Infections 2:55 PM - 4:25 PM Chair: Chris Peacock 2:55pm 3:15pm Gan Lertmemongkolchai (Khon Kaen University, Thailand: 20 min) “Human immune responses to Burkholderia pseudomallei: Research at the centenary of the first description of melioidosis” Andrew Thompson (Murdoch Uni: 20 min) “Emerging Issues and Parasite Zoonoses in the SE Asian Region” 3:35pm 3:50pm 4:05pm 4:15pm 4:25pm Allison Imrie (UWA: 15 min) “Immunodominance in dengue virus infection” Chris Peacock (UWA: 15 min) “Characterization of Australian Leishmaniasis” Rachael Terry (Uni of Sydney: 10 min) “VLA-4 blockade mobilises Ly6chi monocytes in spleen, reduces brain infiltration and increases survival during West Nile Virus” Rama Jayaraj (RMIT University: 10 min) “Evaluation of the immune responses induced by four targeting DNA vaccines encoding the juvenile liver fluke cathepsin B2 antigen in a mouse model” Close of workshop