Marie Smith HLTH 1050 While it is true that many of the drugs that our society condemns have great potential for abuse, some of the drugs being demonized by society have the potential to be used for the treatment of debilitating conditions and for catalyzing personal growth. There is much ongoing scientific research that focuses on potential beneficial uses of illegal drugs such as psilocybin, LSD, and MDMA. There is a great deal of scientific material to draw on regarding these substances from research carried out around the world, both before these substances were made illegal, and after. Most people are familiar with the images associated with psychedelic drugs during the peak of their use in the 1960s: Woodstock, Ken Kesey’s Merry Pranksters, and the Electric Kool-Aid acid tests. Less well known, however, is the research that was done using these drugs in the treatment of many conditions in the 1950s. After Albert Hofmann discovered the psychoactive effects of dlysergic acid diethylamide in 1943, several other physicians conducted and popularized research describing the effects of LSD, Psilocybin and other psychedelics on perception, cognition, emotion, and behavior. “Many people remember vaguely that LSD and other psychedelic drugs were once used experimentally in psychiatry, but few realize how much and how long they were used. Between 1950 and the mid-1960s there were more than a thousand clinical papers discussing 40,000 patients, several dozen books, and six international conferences on psychedelic drug therapy. Today, psychedelic 1 drugs cannot be used in clinical practice but only in research, and only under a special license from the federal government.” (Doblin) When LSD possession was made illegal in the United States in 1968, most research came to an end due to restrictive rules and lack of money. Since then, most people have viewed psychedelics as dangerous and worthless drugs. Now after years of legal difficulties, new studies are being carried out using these substances. One recent study seeks to confirm anecdotal evidence that certain psychedelic drugs are useful in the treatment of cluster headaches. Cluster headaches occur in cyclical patterns or clusters and are one of the most painful types of headache. “The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on the effects of psilocybin and LSD on cluster headache may be warranted.” (Sewell) Another example of an illegal drug with the potential to heal is MDMA. Years before MDMA became part of the rave scene under the street name Ecstasy, it was being used legally as an adjunct to psychotherapy. MDMA’s remarkable ability to lower defense mechanisms and facilitate communication made it an incredible addition to a qualified therapist’s arsenal. In Myron Stolaroff’s book, The Secret Chief, he writes about an anonymous pioneer 2 therapist using MDMA in conjunction with psychotherapy. He writes about one session like this, “Robert describes an experience with MDMA as his most profound psychedelic session… Three hours after the beginning of the session he had a profound experience of God, which he describes as the most joyous moment of his life. A month later he was still happy, joyous, grateful, and completely satisfied. The overall quality of the relationships in Robert's life has improved. He now feels more relaxed around people, more in the present. When dealing with the world at large, Robert no longer feels the need to be constantly on the lookout, scanning for danger. The fear of danger has now fallen away. His fear of death and anxiety levels have also diminished.” (Stolaroff) Now after many years, studies are again being undertaken on the use of MDMA as an adjunct to psychotherapy. The Multidisciplinary Association for Psychedelic Studies has announced a ten-year plan to make MDMA into an FDA-approved prescription medicine. One of the studies they are currently funding involves using MDMA as an adjunct to therapy with veterans suffering from Post-Traumatic Stress Disorder. This study has been approved by the FDA and the DEA and is currently seeking subjects. (MAPS) One former Army Ranger who participated in the pilot study remarked, “It’s basically like years of therapy in two or three hours. You can’t understand it until you’ve experienced it.” (Mitchell) The research so far has illustrated the possibilities for using psychedelic substances to treat disorders and assist in the therapy process, but it does not stop there. Research is also currently being done on the uses of psychedelic drugs for personal and spiritual growth. This research has its roots in the 1962 3 experiment carried out at Boston University’s Marsh Chapel. Walter Pahnke performed this study, but long-term follow-ups were never done due to his death in 1971. “On Good Friday, 1962, before services commenced in Boston University's Marsh Chapel, Walter Pahnke administered small capsules to twenty Protestant divinity students. Thus began the most scientific experiment in the literature designed to investigate the potential of psychedelic drugs to facilitate mystical experience (Pahnke, 1963, 1966, 1967, 1970; Pahnke & Richards, 1969a, 1969b, 1969c). Half the capsules contained psilocybin… and the other half contained a placebo. According to Pahnke, the experiment determined that "the persons who received psilocybin experienced to a greater extent than did the controls the phenomena described by our typology of mysticism" (Pahnke, 1963, p. 220).” (Doblin) A new research study undertaken by the Multidisciplinary Association for Psychedelic Studies and the Johns Hopkins University School of Medicine was designed to reexamine the results of this landmark study. “Using unusually rigorous scientific conditions and measures, Johns Hopkins researchers have shown that the active agent in “sacred mushrooms” can induce mystical/spiritual experiences descriptively identical to spontaneous ones people have reported for centuries. The resulting experiences apparently prompt positive changes in behavior and attitude that last several months, at least.” (Johns Hopkins) Researchers were able to show conclusively that “Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning 4 and spiritual significance” (Griffiths). “In the study, more than 60 percent of subjects described the effects of psilocybin in ways that met criteria for a “full mystical experience” as measured by established psychological scales. One third said the experience was the single most spiritually significant of their lifetimes; and more than two-thirds rated it among their five most meaningful and spiritually significant. Griffiths says subjects liken it to the importance of the birth of their first child or the death of a parent. Two months later, 79 percent of subjects reported moderately or greatly increased well-being or life satisfaction compared with those given a placebo at the same test session. A majority said their mood, attitudes and behaviors had changed for the better. Structured interviews with family members, friends and co-workers generally confirmed the subjects’ remarks.” (Johns Hopkins) This study was important for establishing that psilocybin can induce mystical experiences. This research is ongoing, and further follow-ups are planned. Psychoactive drugs such as psilocybin, MDMA, and LSD have the potential to give relief to those suffering from debilitating headaches and posttraumatic stress disorder. They can also assist in psychotherapy by opening a person up, lowering defense mechanisms and facilitating communication, thus aiding personal and spiritual growth. While these drugs do have the potential for harm when abused, the research clearly shows that they have the potential to heal and help when used properly. 5 Works Cited Doblin, Rick, Jerome E. Beck, Kate Chapman, and Maureen Alioto. "Dr. Oscar Janiger's Pioneering LSD Research: A Forty Year Follow-up." Bulletin of the Multidisciplinary Association for Psychedelic Studies 9.1 (1999): 7-21. Web. 15 Dec. 2011. 6 Sewell, R. A. "Response of Cluster Headache to Psilocybin and LSD." Neurology 66.12 (2006): 1920-922. Print. Stolaroff, Myron J. "Appendix 1." The Secret Chief. Charlotte, NC: Multidisciplinary Association for Psychedelic Studies, 1997. Print. Mitchell, Bryan. "'Party' Drug Could Be PTSD Treatment." Military.com. 4 Mar. 2009. Web. 15 Dec. 2011. <http://www.military.com/news/article/party-drugcould-be-ptsd-treatment.html>. "MDMA-Assisted Psychotherapy." Multidisciplinary Association for Psychedelic Studies. Web. 15 Dec. 2011. <http://www.maps.org/research/mdma/>. Griffiths, R. R., W. A. Richards, U. McCann, and R. Jesse. "Psilocybin Can Occasion Mystical-type Experiences Having Substantial and Sustained Personal Meaning and Spiritual Significance." Psychopharmacology 187.3 (2006): 268-83. Print. "HOPKINS SCIENTISTS SHOW HALLUCINOGEN IN MUSHROOMS CREATES UNIVERSAL “MYSTICAL” EXPERIENCE." Johns Hopkins Medicine, Based in Baltimore, Maryland. Media Relations and Public Affairs, 11 July 2006. Web. 16 Dec. 2011. <http://www.hopkinsmedicine.org/Press_releases/2006/07_11_06.html>. 7