Basic Formal Ontology 2.0 DRAFT DOCUMENT Corresponding author: Barry Smith 2/8/2016 8:28 PM Summary of most important changes (as compared to BFO 1.1) • Clarification of BFO:object The document emphasizes that Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity The document provides a more extensive account of what 'Object' means (roughly: an object is a maximal causally unified material entity); it offers three paradigms of causal unity (for cells and organisms, for solid portions of matter, and for engineered artifacts) • New simplified treatment of boundaries and regions In BFO 1.1 the assumption was made the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document embraces the view that when we talk about a 'surface' there, then we are talking about something fiat. The focus in discussion of boundaries is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. Boundaries thus become more closely allied with spatial regions. • Treatment of process predications under the heading ‘Process profiles’ To assert, for example, that this process is a 72 beats per minute process, is not to ascribe a quality to the process, but rather to assert that there is a certain structural part of the process, called a 'beat profile', which instantiates the determinate universal: 72 beats per minute process. Still missing Treatment of frame-dependence of regions of space and of regions of time Exhaustive treatment of instance-level relations; definitions of type-level relations. Acknowledgments/Authors: Mauricio Almeida, Mathias Brochhausen, Werner Ceusters, Albert Goldfain, Pierre Grenon, Janna Hastings, Chris Mungall, Darren Natale, Fabian Neuhaus, Alan Ruttenberg, Mark Ressler + NAMES TO BE ADDED The references supplied are for preliminary orientation only. Axioms and definitions included therein are not necessarily in conformity with the content of this document. Use of bold face indicates a label for an instance-level relation. Use of italic indicates a BFO term. Contents Introduction ........................................................................................................................................ 1 1. Entity ............................................................................................................................................... 2 Relations of parthood ..................................................................................................................... 3 2. Continuant ....................................................................................................................................... 4 Relation of specific dependence ..................................................................................................... 5 2.1 Independent Continuant............................................................................................................ 6 2.1.1 Material entity ...................................................................................................................... 7 2.1.1.1 Object .......................................................................................................................... 8 2.1.1.2 Object aggregate ....................................................................................................... 13 2.1.1.3 Fiat object part .......................................................................................................... 14 2.1.2 Immaterial entity ................................................................................................................ 16 2.1.2.1 Continuant fiat boundary .......................................................................................... 16 2.1.2.1.1 Zero-dimensional continuant fiat boundary ...................................................... 17 2.1.2.1.2 One-dimensional continuant fiat boundary ....................................................... 18 2.1.2.1.3 Two-dimensional continuant fiat boundary ...................................................... 18 2.1.2.3 Spatial region............................................................................................................. 20 2.1.2.3.1 Zero-dimensional spatial region......................................................................... 21 2.1.2.3.2 One-dimensional spatial region (aka spatial line) .............................................. 21 2.1.2.3.3 Two-dimensional spatial region (aka spatial volume)........................................ 22 2.1.2.3.4 Three-dimensional spatial region...................................................................... 22 Location relations .......................................................................................................................... 22 Relation of containment ............................................................................................................... 23 2.2 Specifically dependent continuant .......................................................................................... 23 Relation of specific dependence ................................................................................................... 23 2.2.1 Quality ................................................................................................................................. 24 2.2.1.1 Relational quality....................................................................................................... 25 2.2.2 Realizable entity .................................................................................................................. 25 Relation of realization ................................................................................................................... 25 2.2.2.1Role (Externally-Grounded Realizable entity) ............................................................ 26 2.2.2.2Disposition (Internally-Grounded Realizable entity).................................................. 27 2.2.2.3Function ..................................................................................................................... 28 2.3 Generically dependent continuant ......................................................................................... 29 Relation of concretization ............................................................................................................. 31 3. Occurrent ....................................................................................................................................... 32 Occupies relation .......................................................................................................................... 33 Relation of temporal parthood ..................................................................................................... 34 Relation of boundary-dependence for occurrents ........................................................................ 34 Process .............................................................................................................................................. 35 Process boundary .............................................................................................................................. 35 Spatiotemporal region ...................................................................................................................... 45 Temporal region ................................................................................................................................ 46 Zero-dimensional temporal region ....................................................................................... 46 One-dimensional temporal region ........................................................................................ 46 1 Introduction This document is a guide for those using Basic Formal Ontology (BFO) as an upper-level ontology to support the creation of domain ontologies containing terms referring to particulars of different sorts. BFO is a formal ontology, which means that it is designed to be neutral with regard to the material domains to which it is applied. The application of a formal ontology such as BFO brings benefits of reuse, cumulation of data, and reasoning, and provides a set of common formal theories (for example of mereotopology [5] and of qualitative spatial reasoning [18]) which do not need to be redeveloped for each successive domain. For such benefits to be achievable, however, BFO must be capable of being applied to material domains and in what follows we document how such application is to be effected. We describe the conditions which must be satisfied by entities of given sorts if they are properly to be categorized as instantiating the different universals recognized by BFO and we provide a summary of the associated relations. To specify these conditions we will utilize a semi-formalized English that has approximately the expressivity of first-order logic (FOL) with identity. In a future document we will provide a formalized treatment of these specifications using FOL; a parallel effort is also underway using OWL. BFO 2.0 Draft Document 2 1. Entity We distinguish primitive and defined terms and relation expressions. The former are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these terms, therefore, we can provide only elucidations, supplemented by examples and by axioms. Elucidation: An entity is anything that exists. Axiom: Entities may be either particular or also universal. [22, 19] In this document we concentrate primarily on entities which are particulars and on the relations between particulars elsewhere called ‘instance-level relations’ [16]. That is, the categories discussed below are in every case categories of particulars (their extensions are groups or collections of particulars in reality). Because BFO is the ontology that forms the basis of the Information Artifact Ontology and universals are included among the targets of the IAO: about relation, BFO must include universals within its domain of discourse. We use ‘universal’ and ‘type’ as synonyms, and employ ‘category’ to refer to the higher-level universals to which BFO terms refer. These and related technical terms of ontology are elucidated further in [19, 25, 17]. Attributive classes Often, language is used to refer to subgroups of entities which instantiate a given universal but do not correspond to any subuniversal. We refer to such subgroups as ‘attribute classes’ (labeled ‘defined classes’ in [25]). Examples are: animal owned by the emperor, tuberculosis diagnosed on a Wednesday, surgical procedure performed in Albania. In some cases, terms of this sort need to be included in domain ontologies. The terms in question should then be defined as children of the corresponding genus (here: animal and tuberculosis, respectively), but they should not treated be as part of the asserted hierarchy of the ontology in question [19]. One major set of examples of attributive classes involve roles. Thus ‘professor’ (defined as: a human being who has the professor role) denotes an attributive class, and so also do ‘nurse’, ‘student’, ‘colonel’ and so forth. BFO 2.0 Draft Document 3 Attributive classes include also what we will call historical classes – classes whose members satisfy some historical condition, for example: biological father, person identified as candidate for clinical trial #2056-555, or person who has visited Pittsburgh. For biological father, the correct form of definition is roughly as follows: biological_father(a) =Def. a instantiates the universal human being & a is male & there some some zygote b & there is some some child c & there is some process of fertilization d & b output_of c & a agent_of c & c = a. Definitions We distinguish between terms, which are lables for universals and attributive classes, and relational expressions, which are labels for relations [16]. Definitions of terms are always of the form an S =Def. a G which Cs where ‘S’ (for: species) is the term to be defined, ‘G’ (for: genus) is the immediate parent term of ‘S’ in the relevant BFO-conformant ontology, and ‘D’ (for: differentia) specifies what it is about the G’s which makes them S’s. Attributive classes can be defined by using as genus any BFO-conformant universal below entity. Relations of parthood Primitive relations a part_of b at t – where relata are continuants a part_of b – where relata are occurrents BFO 2.0 Draft Document 4 The mereology used in each case is Simple Extensional Mereology as defined in [46]. Note that ‘part_of’ in BFO signifies always: ‘proper or improper part’. Thus every entity, from the BFO point of view is, trivially, a part of itself. Relations defined in terms of part-of a has_part b = Def. b part_of a a has_part b at t = Def. b part_of a at t The above are instance-level relations; we will supply the associated type-level relations in a later version of this document, along the lines set forth in [16]. 2. Continuant Elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. Axiom: if a is a continuant and b is part_of a then b is a continuant (Continuants have no temporal parts.) Theorem: if a is a continuant and a is part_of b then b is a continuant. Axiom: if a is a continuant at some time, then there is some one-dimensional temperal region (some temporal interval) during which a exists. Note: Continuants may persist for very short periods of time (as for example in the case of a highly unstable isotope). BFO 2.0 Draft Document 5 Relation of specific dependence Elucidation: To say that a s-depends on b is to say that: a exists & a is of its nature such that, if for some t, a exists at t then b exists at t also & a and b share no common parts. Theorem: an entity does not s-depend on any of its parts. However, the parts of an entity may s-depend on each other. If a s-depends on b, then we can also say that a necessitates the existence of b; is tied of its nature to b. If a s-depends, then it s-depends at every time at which it exists. If b is such that some a sdepends on it, then if b ceases to exist, so also does that something. The entities which s-depend include dependent continuants, which s-depend either on each other or on the independent continuants which are their bearers, and occurrents, which s-depend either on each other or on the independent continuants which participate in them. [46, chapter 8; 20, 22] Examples of one-sided s-dependence of a dependent continuant on an independent continuant: a headache on a head an instance of temperature on some organism a smile on a human face a process of cell death and a cell (where the ceasing to exist of the cell marks the end of the process) Examples of reciprocal s-dependence between dependent continuants: roles of husband and wife [20] three-sided reciprocal dependence of the hue, saturation and brightness of a color [45] three-sided reciprocal dependence of the pitch, timbre and loudness of a tone [45] BFO 2.0 Draft Document 6 Examples of reciprocal s-dependence between occurrents: a process of playing with the white pieces in a game of chess is reciprocally dependent on a process of playing with the black pieces in the same game of chess a process of buying and the associated equal and opposite process of selling a process of increasing the volume of a body of gas at fixed temperature and the associated process of decreasing the volume Examples of one-sided s-dependence of one occurrent on another a process of answering a question is dependent on a prior process of asking a question a process of obeying a command is dependent on a prior process of issuing a command 2.1 Independent Continuant A is an independent continuant = Def. a is a continuant which is such that there is no b such that a sdepends on b Examples: an atom, a molecule, an organism, a heart, a chair, the bottom right portion of a human torso, a leg; the interior of your mouth; a spatial region; an orchestra. Note that the use of ‘of’ here (as in: ‘interior of your mouth’) does not indicate s-dependence. Sdependence holds only where the s-dependent entity or entities involved have what was traditionally referred to as a ‘lesser degree of being’ than the associated independent continuant bearers (as a color has a lesser degree of being than a colored thing). Axiom: Every independent continuant is such that there are entities which inhere in it. Examples: qualities, dispositions, processes. Subtypes of independent continuant: BFO 2.0 Draft Document 7 material entity object fiat object part object aggregate immaterial entity continuant fiat boundary zero-dimensional continuant fiat boundary one-dimensional continuant fiat boundary two-dimensional continuant fiat boundary site spatial region zero-dimensional region one-dimensional region two-dimensional region three-dimensional region 2.1.1 Material entity Elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper part. Thus every material entity is extended in 3 spatial dimensions. Examples: human beings, undetached arms of human beings, aggregates of human beings. Axiom: every entity which has a material entity as part is a material entity Theorem: every entity of which a material entity is part is a also a material entity. ‘Matter’ here is intended in the sense of physics, as something which includes elementary particles among its proper or improper parts: quarks and leptons at the most fundamental level of granularity; protons, neutrons and electrons at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists. BFO 2.0 Draft Document 8 Material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of you. 2.1.1.1 Object BFO rests on the presupposition that the material universe is built to a large degree out of separate or stable, spatially separated or separable units, combined or combinable into aggregates called groups, populations, or collections. Many scientific laws govern the units in question, and the units play a central role in almost all domains of natural science from particle physics to cosmology. The division of reality into such stable natural units, and the fact that these units form aggregates such as families, herds, populations, breeds, species, and so on, is at the heart of biological science. The division of certain portions of reality into engineered units is the basis of modern industrial technology, which rests on the distributed mass production of pre-engineered parts through division of labor and on their reassembly into larger, compound units such as cars and laptops. The division of portions of reality into units is the basis also of the phenomenon of counting. Clearly not all material entities form separated or separable natural units in this way (see Figure 1 and [12]). Figure 1: Mount Everest from space BFO 2.0 Draft Document 9 Examples of units of special importance for the purposes of natural science include: atom, molecule, organelle, cell, organism, planet, star. These material entities are candidate examples of what called ‘objects’ in BFO. Each of the listed types of units is marked by the fact that it has very large numbers of instances. Such units are often referred to as ‘grains’, and are associated with specific ‘levels of granularity’ in what is seen as a layered structure of reality, with units at lower and more fine-grained levels being combined as parts into grains at higher, coarse-grained levels. In what follows, however, we shall formulate our proposals independently of any granularity considerations. Elucidation of BFO:object The following elucidation is provided not as part of a formal theory (of qualitative mereotopology [5, 5, 22, 36, 37, 39]), but rather as a set of conditions to be used when deciding whether entities of a given type should be represented as objects in the BFO sense. Preamble on the strategy Material entities fall into different groups, for instance - of portions of solid matter, portions of liquid, portions of gas - collections of microparticles (which can survive through phase transitions from solid to liquid to gas) - portions of energy (to be included in a future version of BFO). In what follows we consider three candidate groups of examples of objects in the BFO sense, namely: 1. organisms and cells 2. portions of solid matter such as rocks and lumps of iron 3. engineered artifacts such as watches and cars. Material entities under all of these headings are all causally relatively isolated entities in Ingarden’s sense [47, 13]. This means that they are both structured through a certain type of causal unity and maximal relative to this type of causal unity. BFO 2.0 Draft Document 10 We first characterize causal unity in general, we then distinguish three types of causal unity corresponding to the three candidate families of BFO:objects listed above. We then define what it is for an entity to be maximal relative to one or other of these types, and formulate in these terms an elucidation of ‘object’. Elucidation: a is causally unified means: a is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question, if a part in the interior of a is moved in space to a location on the exterior of a then either a’s other parts will be moved in coordinated fashion or a will be damaged (be affected, for example, by breakage or tearing) causal changes in one part of a can have consequences for other parts of a without the mediation of any entity that lies on the exterior of a Material entities with no material subparts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list): CU1: Causal unity via physical covering Here the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering. The latter points outwards toward and serves as a protective function in relation to what lies on the exterior of the entity [13, 47]. Note that the physical covering may have holes (for example pores in your skin, shafts penetrating the planet’s outer crust, sockets where conduits to other entities are connected allowing transport of electric current or of liquids or gases). The physical cover is nonetheless connected in the sense that, between every two points on its surface a continuous path can be traced which does not leave this surface. Some organs in the interior of complex organisms manifest a causal unity of this type. Organs can survive detachment from their surroundings, for example in the case of transplant, with their membranes intact. The FMA [44] accordingly defines ‘organ’ as follows: BFO 2.0 Draft Document 11 An anatomical structure which has as its direct parts portions of two or more types of tissue or two or more types of cardinal organ part which constitute a maximally connected anatomical structure demarcated predominantly by a bona fide anatomical surface. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary. CU2: Causal unity via internal physical forces Here the parts of a material entity are combined together causally by sufficiently strong physical forces (for example, by fundamental forces of strong and weak interaction, by covalent or ionic bonds, by metallic bonding, or by van der Waals forces). In the case of larger portions of matter the consistuent atoms are tightly bound to each other either in a geometric lattice, either regularly (as in the case of portions of metal) or irregularly (as in an amorphous solid such as a portion of glass). CU3: Causal unity via engineered assembly of components Here the parts of a material entity are combined together via mechanical assemblies joined for example through screws or other fasteners. The assemblies often involve parts which are reciprocally engineered to fit together, as in the case of dovetail joints, balls and bearings, nuts and bolts. A causal unity of this sort can be interrupted for a time, as when a watch is disassembled for repair, and then recreated in its original state. The parts of an automobile, including the moving parts, constitute an object because of their relative rigidity: while these parts may move with respect to each other, a given gear cannot move e.g., 10 ft, while the other parts do not. Thus a raindrop on the car is not part of it (nothing prevents it from being moved many feet away from the car) while the oil in the crankcase, and various gears, are parts of the car. We can now elucidate what it means for a material entity to be maximal relative to one or other of these three types of causal unity. Elucidation: a is maximal means that a is causally unified relative to some CUn and there is no b which is also causally unified relative to CUn and which includes a as proper part. Thus conjoined twins sharing vital organs are, prior to separation, not maximal relative to the CU1 type of causal unity. BFO 2.0 Draft Document 12 Elucidation: an object is a material entity which manifests causal unity of one or other of the types listed above (or of some other type to be distinguished in the future) and is maximal relative to the corresponding type of causal unity. Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. (See Figure 2) Figure 2: An example of cell adhesion Some instances of any given BFO:object universal – for example cell or organism or laptop – are separated by spatial gaps from other instances of this same object universal. The spatial gaps may be filled by a lower-density medium, for example of air or water. (There are cells not adjacent to or attached to other cells; there are spatially separated organisms, such as you and me.) Objects may contain other objects as parts They may do this for example by containing atoms and molecules as parts BFO 2.0 Draft Document 13 by containing object aggregates as parts, for instance the collection of blood cells in your body is an object aggregate; by containing objects which are bonded to other objects of the same type in such a way that they cannot (for the relevant period of time) move separately, as in the case of the cells in your epithelium or the atoms in a molecule. in the case of organs (inside an organism) and some types of engineered constituents (inside a physical artifact) parts may be separate (for example they may float in some portion of liquid) or they may be connected together through conduits or tracts which may themselves have covering membranes which themselves lie in the interior of the object. Some objects may also have immaterial parts (the lumen of your gut). Axiom: Objects retain their objecthood for as long as they exist. A human body continues to exist even after being buried in a pile of cement. A watch that has been taken apart for repair ceases to exist for as long as it is disassembled. 2.1.1.2 Object aggregate The term ‘aggregate’ will in a future version of BFO be defined in general terms, in such a way that, for all continuant BFO categories X, the user of BFO will have at his disposal also the category ‘aggregate of X’ [51]. Elucidation: a is an object aggregate = Def. a is a material entity consisting exactly of a plurality of objects as parts. More formally: If a is an object aggregate, then if a exists at t, then there are objects o1, …, on at t such that: for all x (x part of a at t iff x overlaps some oi at t) Object aggregates may be defined through physical attachment (the aggregate of atoms in a lump of granite), or through physical containment (the aggregate of molecules of carbon dioxide in a sealed BFO 2.0 Draft Document 14 container, the aggregate of blood cells in your body). Object aggregates may be defined by fiat – for example in the case of the aggregate of members of an organization, or via attributive delimitations such as ‘the patients in this hospital’, ‘the restaurants in Palo Alto’, ‘your collection of Meissen ceramic plates’. As is true for all material entities (for example: you), object aggregates may gain and lose object parts while remaining numerically identical (one and the same individual) over time. Candidate: Examples: a symphony orchestra, the aggregate of bearings in a crank shaft, 2.1.1.3 Fiat object part a is a fiat object part = Def. a is a material entity that is a proper part of an object and that is, relative to the object’s type of causal unity, not maximal. Since fiat object parts are material entities, they are also extended in space in three dimensions (in contrast to fiat continuant boundaries, introduced below). Examples of fiat object parts: the upper and lower lobes of the left lung, the dorsal and ventral surfaces of the body, the Western hemisphere of the Earth, the FMA:regional parts of an intact human body. Fiat object parts are contrasted with bona fide object parts, which are themselves objects (for example a cell is a bona fide object part of an multi-cellular organism), and are marked by bona fide boundaries, on in other words by physical discontinuities [8, 8]. Most examples of fiat object parts are associated with theoretically drawn divisions, for example the division of the brain into regions, the division of the planet into hemispheres, or with divisions drawn by cognitive subjects for practical reasons the division of a cake (before slicing) into (what will become) slices. However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the earth as fiat object parts of the earth, then even though these layers were first delineated in recent times, still they existed long before such delineation and truths about these layers (for example that the oldest layers are also the lowest layers) did not become true because of any acts of delineation. BFO 2.0 Draft Document 15 Portions of matter are not extra entities BFO (in contrast to DOLCE) is non-multiplicative; it does not distinguish between an object and its constituting matter. The statue is not a second object; it is the portion of bronze during the period when it plays the statue role. If an entity is in one of the three categories – object, fiat object part, object aggregate – at any given time in its existence, then it is so at all times. A leaf (plant organ) falls from a tree. A uterus is explanted. An atom becomes bound up with other atoms in a molecule. A cell becomes bound with another cell in an organism (both cells preserve their existence). A cell divides into two cells (the first cell ceases to exist). Note that object and fiat object part are by definition disjoint (in the sense that they are such as to share no instances in common). However we do not assert that object and fiat object part are disjoint from object aggregate. A pair of parts of your body – for example a pair of blood cells in your leg, may simultaneously be both a fiat object part of your body and an object aggregate. A molecule may simultaneously be both an object its own right and an object aggregate comprised of atoms. A watch is simultaneously both an object and an aggregate of its component parts. Treatment of material entity in BFO Examples of problematic cases which might call forth such extensions include: a muscle on (and attached to) a rock, a slime mold, a slice of cake, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (‘biofilm’), a polypeptide chain, a broken femur. Where users of BFO need to annotate data pertaining to such problematic cases, then they may in every case use BFO:material entity in formulating the corresponding annotations. However it is clear that BFO will need to recognize other sub-universals of material entity, in addition to object, object aggregate and fiat object part – for instance: aggregate of fiat object parts [29]. Thus BFO:material entity should not be associated with any closure axiom and the existing BFO 2.0 Draft Document 16 treatment of the three identified sub-universals should not be associated with any claim to exhaustivity. We will provide a strategy for dealing with such sub-universals in a later version of this document. Briefly, the proposal is that a central repository will be created where users of BFO can create BFOconformant extensions (embracing terms which meet the criterion that they are formal- rather than domain-ontogical, and associating them with suitable definitions and examples). The terms in this repository can then be adopted by others, according to need, and incorporated into BFO if adopted by multiple communities of users. 2.1.2 Immaterial entity The roots of BFO’s treatment of ‘immaterial entity’ lie in the application of theories of qualitative spatial reasoning to the geospatial world for example as outlined in [49], in the treatment of holes by Casati and Varzi [48], and the treatment of cavities in the FMA [43, 44, 34, 35]. Immaterial entities are divided into two subgroups: 1. sites and boundaries, which are tied to material entities, and which can thus change size, shape and location as their material hosts move (for example: the boundary of Wales; your nasal passage; the hull of a ship [38, 7, 10]); 2. spatial regions, which exist independently of material entities, and which thus do not change. Immaterial entities under the former headings are in some cases parts of their material hosts. Immaterial entities under both headings can be of zero, one, two or three dimensions. We define: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. 2.1.2.1 Continuant fiat boundary BFO 2.0 Draft Document 17 a is a continuant fiat boundary = Def. a is an immaterial entity that is of zero-, one- or two dimensions. Axiom: A continuant fiat boundary is of n dimensions iff it is located at some n-dimensional spatial region. Every continuant fiat boundary is located at some spatial region at every time at which it exists (but not necessarily at the same spatial region from one time to the next). All material entities are of three dimensions. Intuitively, a continuant fiat boundary is a boundary of some material entity (for example the plane separating the Northern and Southern hemispheres, the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds): fiat boundaries which closely coincide with the material surfaces of material entities or with other physical discontinuities; when we program a telesurgical device for purposes of targeting an incision through the surface of your skin, then we might represent this surface as a two-dimensional plane (for the purposes of the device, the differences between this twodimensional fiat plane and the actual surface fall below the threshold of granularity [11]) fiat boundaries which delineate fiat parts within the interiors of material entities – for example the fiat boundary between the northern and southern hemispheres of the Earth; the North Pole; the fiat boundary which separates Utah from Colorado) fiat boundaries which delineate holes or cavities, for example fiat boundaries of the type referred to by the FMA under the heading ‘plane of anatomical orifice’. An example of a combination fiat boundary would be the border of Denmark. 2.1.2.1.1 Zero-dimensional continuant fiat boundary Elucidation: a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. Examples: the North Pole; the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet, the point of origin of some spatial coordinate system. BFO 2.0 Draft Document 18 2.1.2.1.2 One-dimensional continuant fiat boundary Elucidation: a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. To say that a one-dimensional continuant fiat boundary is continuous is to assert that it contains no gaps. Examples: The Equator, all geopolitical boundaries, all lines of latitude and longitude, the median sulcus of your tongue. 2.1.2.1.3 Two-dimensional continuant fiat boundary Elucidation: a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. ‘Self-connected’ here and in what follows is to be understood in the following (topological) sense; thus to assert that an entity a is self-connected is to assert that given any two points in a, there is a continuous line in a which connects these points. From this it follows that a two-dimensional continuant fiat boundary (surface) may have holes, as for example in the case of the surface of one side of a compact disk. Examples: see Table 1. BFO 2.0 Draft Document 19 Table 1. Fragment of Foundational Model of Anatomy Anatomical boundary entity Anatomical surface Bona fide anatomical surface Anatomical plane Anchored anatomical plane Craniocervical plane Cervicothoracic plane Thoraco-abdominal plane Occipital plane Interspinous plane Plane of anatomical orifice Anatomical transverse plane Plane of anatomical junction Sagittal midplane of body 2.1.2.1.4 Site a is a site = Def. a is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or a three-dimensional immaterial part thereof. Examples: a hole in the interior of a portion of cheese, a rabbit hole, the interior of this room, the Grand Canyon, the Piazza San Marco, an air traffic control region defined in the airspace above an airport, a kangaroo pouch, your left nostril, the hull of a ship, the lumen of your gut, the interior of the trunk of your car, the interior of your refrigerator, the interior of your office, Manhattan Canyon) Note: Sites may be bounded in part by fiat boundaries, as for instance the Mont Blanc Tunnel is bounded by fiat boundaries at either end. Each immaterial entity coincides at any given time with some spatial region, but, as in the case of material entities, which spatial region this is may vary with time. As the ship moves through space, so its hull moves also. As you pinch and unpinch your nose, your nostril dilates and expands. The class A region of controlled airspace is a site, since it is a three-dimensional part of the site formed by the sum of this region with the portion of the class E region that is bounded by the surface of the Earth (see Figure 3). BFO 2.0 Draft Document 20 Figure 3: Airspace classes Cavities within what Ontology for General Medical Science (OGMS) calls the ‘extended organism’ are sites; they are parts of the organism if they are part of its organisms anatomical Bauplan [43, 44]. Thus a cavity created by an incision with a knife is not a part of the organism. 1 2 3 4 Figure 4: Examples of types of site 1: the interior of an egg; 2: the interior of a snail’s shell; 3: the environment of a pasturing cow 2.1.2.3 Spatial region In a later version of this document we will document the way in which every spatial and every temporal region is dependent on a reference frame. (Spatiotemporal regions, in contrast, are independent of reference frame.) BFO 2.0 Draft Document 21 We recommend that users of BFO:spatial region specify the coordinate frame which they are employing. When dealing with spatial regions on the surface of the Earth, for example, this will be the coordinate frame of latitude and longitude, potentially supplemented by the dimension of altitude (height above sea level). Such coordinate frames can be associated with a Newtonian or a relativistic frame of reference. The reference frame might be defined in relation to a moving object such as the earth, in which case the corresponding spatial regions move with the movement of the earth. However, they are at rest relative to their coordinate frame. Lines of latitude and longitude are twodimensional object boundaries which can move; however, they are by definition at rest relative to the coordinate frame which they determine. Elucidation: A spatial region is, intuitively, a zero-, one-, two- or three-dimensional part of the space in which objects move and are located. Spatial regions have no qualities except shape, size and relative location. Object boundaries and sites are distinguished from the spatial region which they occupy at any given time in the sense that (1) the former move when their material host moves, and they change shape or size when their material host changes shape or size; (2) the latter must be specifiable in terms of some system of coordinates, and they are by definition at rest relative to this coordinate frame. 2.1.2.3.1 Zero-dimensional spatial region Elucidation: a point in space. 2.1.2.3.2 One-dimensional spatial region (aka spatial line) Elucidation: a continuous line stretching from one point in space to another Examples: an edge of a cube-shaped portion of space. BFO 2.0 Draft Document 22 2.1.2.3.3 Two-dimensional spatial region (aka spatial volume) Def. a self-connected spatial region of two dimensions. Examples: the surface of a sphere-shaped part of space, an infinitely thin plane in space. When the dependence of spatial regions on reference frames is documented, then we will document also the relations between spatial regions defined relative to the (reference frame that is determined by the Earth), and the corresponding sites and continuant fiat boundaries. 2.1.2.3.4 Three-dimensional spatial region Def. a self-connected spatial region of three dimensions. Examples: a cube-shaped region of space, a sphere-shaped region of space, Location relations Located_at Elucidation: a located_at r at t This is a primitive relation between an independent continuant, a spatial region which it occupies, and a time. Axiom: every region is located_at itself at all times. Axiom: if a located at r at t & a part_of a at t, then there is some r which is part_of r & such that a located_at r at t. Located_in a located_in b at t = Def. a and b are material entities, and the region occupied by a is a (proper or improper) part_of the region occupied by b. BFO 2.0 Draft Document 23 Examples: your heart located_in your body; this stem cell located_in this portion of bone marrow; this portion of cocaine located_in this portion of blood. Relation of containment Elucidation: a contained_in b at t means: a is a material entity & b is a site & for all spatial regions r1, r2, if a located_at r1 at t and b located_at r2 at t, then r1 part_of the of r2 & if b is moved a sufficient distance in space then this will cause a to be moved also in virtue of its position in relation to b. (To see why this additional condition is needed see [52].) A site is something in which a material entity can be contained. Note that there are other sub-universals of immaterial entity, in addition to site, continuant fiat boundary and spatial region. For instance: aggregate of sites, aggregate of spatial regions. The part of space occupied by a pair of non-adjacent cubes is not a spatial region but an aggregate of spatial regions. All parts of spatial regions are fiat parts, since no boundaries of spatial regions are physical discontinuities. 2.2 Specifically dependent continuant Relation of specific dependence a s-depends on b at t = Def. a exists at t & a s-depends on b a is a specifically dependent continuant =Def. a is a continuant which s-depends on some entity. Sub-types of specifically dependent continuant recognized by BFO are: quality BFO 2.0 Draft Document 24 relational quality realizable entity role disposition function Examples: the mass of this tomato, the color of this tomato, the smell of this portion of mozzarella, the disposition of this fish to decay, the role of being a doctor, the function of this heart: to pump blood, the function of this key to open this lock and the reciprocally dependent disposition of this lock: to be opened by this key, John’s love for Mary. a inheres in b =Def. a is a dependent continuant & b is an independent continuant & a s-depends on b Inherence is a subrelation of specific dependence which holds between a dependent continuant and an independent continuant. a bearer_of b at t = Def. b s-depends on a at t or b g-depends_on a at t ‘Bearer’ is a shorthand term of convenience. 2.2.1 Quality Elucidation: a quality is an specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. Solubility, in order to be realized or manifested, requires a process in which some solid piece of salt or sugar participates. Their crystalline quality, in contrast, does not stand in need of any realization process of this sort. BFO 2.0 Draft Document 25 Examples: the color of a tomato, the ambient temperature of a portion of air, the length of the circumference of your waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee. Axiom: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. For some qualities, e.g. surface color, s-dependence is not on the material bearer but rather on its surface. a quality_of b at t = Def. a is a quality & b is a material entity & a s-depends_on b at t Qualities of spatial regions are restricted to qualities of size, shape and location. 2.2.1.1 Relational quality There are relational qualities, for example: loves, taller_than, which have a plurality of independent continuants as their bearers. a is a relational quality =Def. for some independent continuants b, c and for some time t: a quality_of b at t & a quality_of c at t & a and b have no parts in common 2.2.2 Realizable entity a is a realizable entity = Def. a is a specifically dependent continuant that inheres in some material entity and is of a type instances of which are realized in processes of a correlated type. Examples: the role of being a doctor, the function of your reproductive organs, the disposition of your blood to coagulate, the disposition of this piece of metal to conduct electricity. Relation of realization BFO 2.0 Draft Document 26 Elucidation: if a realizes b at t, then there is some material entity c & a is a process in which c participates at t & b is a disposition or role of which c is bearer. Note that t here ranges over temporal intervals, rather than over instants of time (temporal boundaries). There are also reciprocal realizable dependent continuants (e.g. husband/wife; complementary dispositions (for example of key and lock), as described in [28]). Axiom: if a realizable entity is realized in a process p, then its bearer participates in p. 2.2.2.1 Role (Externally-Grounded Realizable entity) Elucidation: a is a role means: a is a realizable entity which exists because its bearer is in some special physical, social, or institutional set of circumstances in which the bearer does not have to be, and is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. ‘Role’ is another name for what we might call an extrinsic or externally-grounded realizable entity. An entity is a role not because of the way it itself is, but because of something that happens or obtains externally. Examples include: the role of an instance of a chemical compound to serve as analyte in an experiment the role of a stone in marking a boundary the role of a priest in baptizing an infant Optionality of Roles Because a role is not a consequence of the in-built physical make-up of its bearer, roles are optional in the sense that the bearer of a role can lose this role without being thereby physically changed. Most of the roles we here distinguish involve some form of social ascription or imputation. Candidate non-social roles however include positional roles – for example a given protein plays the role of peripheral membrane protein. The roles of a bacteria in giving rise to an infection, or of a portion of water in helping to initiate the growth process of a seed, are also positional in this sense. In BFO 2.0 Draft Document 27 both cases we have many examples (of bacteria, of portions of water) only some of which are in the position where they play, respectively, the infecting and the growth-supporting roles. Having a role vs. playing a role An entity can play a role, as when a passenger plays the role of a pilot on a commercial plane in an emergency, or a pyramidal neuron plays the role occupied by a damaged stellar neuron in the brain; but neither the person nor the pyramidal neuron have those roles. Attributive role classes The correct form for generating phase sortal expressions designating attribute classes and involving reference to roles is as follows: student(a, t) = Def. a has_role student role at t Here ‘student(John, t)’ means: John is a member_of the attributive class student at t. 2.2.2.2 Disposition (Internally-Grounded Realizable entity) Elucidation: a is a disposition means: a is a realizable entity which is such that (1) if it ceases to exist, then its bearer is physically changed, and (2) its realization occurs when this bearer is in some special physical circumstances, and (3) this realization occurs in virtue of the bearer’s physical makeup. Examples: an atom of element X has the disposition to decay to an atom of element Y the cell wall is disposed to filter chemicals in endocitosis and exocitosis certain people have a disposition to develop colon cancer children are innately disposed to categorize objects in certain ways. Unlike roles, dispositions are not optional. If an entity is a certain way, then it has a certain disposition, and if its physical makeup is changed then it may lose that disposition. A disposition can for this reason also be referred to as an internally-grounded realizable entity. That is, it is a realizable BFO 2.0 Draft Document 28 entity that is a reflection of the in-built or acquired physical make-up of the independent continuant in which it inheres. Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of entities of a similar type. Each disposition type is associated with one or more characteristic realization process types – instantiated by those processes in which it is realized. Dispositions may also be associated with characteristic trigger process types – instantiated by processes (for example of being dropped on a hard surface) in which they are realized. Diseases are dispositions according to OGMS [27]. We are referring to disposition also when we consider genetic and other risk factors for specific diseases. These are predispositions to disease – in other words they are dispositions to acquire certain further dispositions. The realization of such a predisposition consists in processes which change the physical makeup of its bearer in such a way that parts of this bearer then serve as the physical basis for a disease. This physical basis is referred to be OGMS as a disorder. 2.2.2.3 Function A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. Examples include: the function of amylase in saliva to break down starch into sugar the function of a hammer to drive in nails the function of a heart pacemaker to regulate the beating of a heart through electricity Functions are realized in processes called functionings. Each function has a bearer with a specific type of physical make-up. This is something which, in the biological case, the bearer has naturally evolved to have (as in a hypothalamus secreting hormones). In the artifact case, it is something which the bearer has been constructed to have (as in an Erlenmeyer flask designed to hold liquid) or also (as in the case of penicillin) selected for. BFO 2.0 Draft Document 29 It is not accidental or arbitrary that a given eye has the function to see or that a given screwdriver has been designed and constructed with the function of fastening screws. Rather, these functions are integral to these entities in virtue of the fact that the latter have evolved, or been constructed, to have a corresponding physical make-up. Thus the heart’s function is to pump blood, and not merely to make thumping produce sounds. The latter are by-products of the heart’s proper functioning. The screwdriver’s function is in addition bound together with the disposition of the screw: the two are reciprocally dependent on each other (a case of reciprocal generic dependence). Like dispositions of other sorts, a function is an internally-grounded realizable entity: it is such that, if it ceases to exist, then its bearer is physically changed. In some cases an entity may preserve its function even while it is physically changed in ways which make it unable to function. For a lung or attic fan to be non-functioning is an indication that the physical make-up of these things has changed – in the case of the lung perhaps because of a cancerous lesion; in the case of the attic fan because of a missing screw. But these entities then still have their functions; it is simply that they are unable to exercise these functions until the physical defect is rectified, for example through clinical intervention or mechanical repair. The entities would lose their function only if they were changed drastically, for example by being permanently removed from the body in the case of the lung, or by being irreparably crushed in the case of the attic fan. We can distinguish two varieties of function, artifactual function and biological function. These are not subtypes of BFO:function however, since the same function – for example: to pump – can exist both in artifacts and in biological entities. Rather the relevant difference in type exists here on the side of the respective bearers. Defined relations: a role_of b at t = Def. a is a role and a inheres_in b at t a disposition_of b at t =Def. a is a disposition and a inheres_in b at t a function_of b at t = Def. a is a function and a inheres_in b at t 2.3 Generically dependent continuant BFO 2.0 Draft Document 30 a g-depends on b at t1 = Def. a exists at t1 and b exists at t1 and for some type B it holds that (b instantiates B at t1) and necessarily, for all t (if a exists at t then some instance_of B exists at t) Axiom: if a g-depends on b at some time t, then a g-depends on something at all times at which it exists. a is a generically dependent continuant =Def. a is a continuant that generically depends on one or more other entities. Example: the pdf file on your laptop, the pdf file that is a copy thereof in my laptop; the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule. Where BFO’s specifically dependent continuants are subject to what we might call the axiom of nonmigration – they cannot migrate from one bearer to another – generically dependent continuants are able to migrate, through a process of exact copying. The very same pdf file can be saved to multiple storage devices, and thus it can exist in multiple copies. We can think of generically dependent continuants, intuitively, as complex continuant patterns (complex qualities) of the sort created by authors or designers, or (in the case of DNA sequences) through the processes of evolution. Further examples of generically dependent continuants include: the chessboard pattern, the Coca Cola logo, the pattern of a traffic sign. Each such pattern exists only if it is concretized in some counterpart specifically dependent continuant – the pattern of black and white squares on this wooden chessboard here before me; the pattern of red and white swirls on the label of this Coca Cola bottle; the pattern of paint on this traffic signboard; your social security number; your recipe for spaghetti carbonara. Such patterns can be highly complex. The pattern of letters of the alphabet and associated punctuation and spacing which is the novel Robinson Crusoe is concretized in the patterns of ink marks in this and that particular copy of the novel. When you create a novel then in addition to creating an s-dependent pattern of inkmarks on your manuscript, you create also a particular instance of the generically dependent continuant type novel. When you print further copies in book form, then you create multiple particular instances of the independent continuant type book. BFO 2.0 Draft Document 31 Relation of concretization a concretizes b at t = Def. a is a specifically dependent continuant & b is a generically dependent continuant & for some independent continuant c, a s-depends on c at t and b g-depends on c at t, and if b migrates from bearer c to another bearer d than an exact copy of a will be created in d. The data in your database are patterns instantiated as s-dependent quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type datum. Data, databases, pdf files, novels, and other information artifacts are thus analogous to other created artifacts such as paintings or sculptures. They differ from the latter, however, in that, once they have been created, they can exist in many copies that are all of equal value. These many copies exist because of a templating process. Only where such a templating process exists do we have the sorts of patterns which are generically dependent continuants. Generically dependent continuants can be concretized in multiple ways; you may concretize a poem as a pattern of memory traces in your head. You may concretize a piece of software by installing it in your computer. You may concretize a recipe which you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head. Axiom: if a g-depends on b at some time, then there is some c, a concretization of a, which sdepends on b. Works of Music and Experimental Protocols In the case of a work of music such as Beethoven’s 9th Symphony, there is a certain abstract pattern, a generically dependent continuant, which we shall call #9. #9 is an instance of the type symphony, which is itself a subtype of the type musical work. #9 is concretized in certain specifically dependent continuant patterns of ink marks that we find in printed copies of its score, or in certain specifically dependent continuant patterns of grooves in vinyl disks. The score is an instance of the generically BFO 2.0 Draft Document 32 dependent continuant type plan specification, specifying how to create a corresponding musical performance. This plan specification is concretized in distributed fashion in the form of a network of subplans distributed across the minds of the conductor and the members of the orchestra, together forming a plan to create a musical performance of #9. This complex realizable dependent continuant is then realized when conductor and orchestra work together to create a certain pattern of air vibrations conforming to the score and audible to an audience. Analogously, when a research team decides to perform an experiment following a published protocol, the protocol itself is a generically dependent continuant instance of the type plan specification. The leader of the research team concretizes this protocol in her mind to create that specifically dependent realizable continuant which is her plan for carrying out this experiment. At the same time she creates a series of sub-protocols, plan specifications for her various team members. These plan specifications are concretized in the minds of the team members as plans for carrying out corresponding subactivities within the experiment. The experiment itself is a realization of these plans, having outputs such as publications, databases, and so forth, as described in the Ontology for Biomedical Investigations (OBI). 3. Occurrent The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Those natural which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side (for example in the cases of births and deaths, and of similar object-bound process boundaries), or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance separating billiard balls or zebrafish or planets by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other pre-life processes such as fertilization and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of BFO 2.0 Draft Document 33 processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate). Processes can be arbitrarily summed and divided. In particular, we can identify sub-processes which are fiat segments occupying constituent temporal intervals of the temporal interval occupied by the process as a whole – for example your heart-beating from 4pm to 5pm today; the 4th year of your life. Elucidation: an occurrent is an entity that has temporal parts. Examples: the life of an organism, a surgical, the spatiotemporal setting occupied by a process of cellular meiosis, the most interesting part of Van Gogh’s life, the spatiotemporal region occupied by the development of a cancer tumor. Since temporal regions are temporal parts of themselves this means that 0-dimensional temporal regions are also occurrents. Subtypes of occurrent are: process process profile process boundary temporal region zero-dimensional temporal region one-dimensional temporal region spatiotemporal region Projection relations spatiotemporal region projects_onto temporal region spatiotemporal region projects_onto spatial region at t Occupies relation BFO 2.0 Draft Document 34 Elucidation: a occupies r. This is a primitive relation between an occurrent and a temporal or spatiotemporal region which it exactly occupies. The occupies relation is the counterpart, on the occurrent side, of the relation located_at. Trivially, every spatiotemporal or temporal region occupies itself. Relation of temporal parthood Elucidation: To say that a is a temporal_part_of b is to say that a part_of b & a and b are occurrents & for some spatiotemporal or temporal region r, a occupies r & b occupies a region including r as part. Histories The history of a material entity is the totality of processes taking place in the spatiotemporal region occupied by the entity, including processes on the surface of the entity or within the cavities to which it serves as host. (See the OGMS definition of ‘extended organism’.) In the case of organisms histories are what we normally call ‘lives’ [15], and in the case of sentient organisms lives will include also the experiences of the organism. If, for example, you experienced the Second World War, then the Second World War is in this sense a part of (or better: is involved in your history). The history of a material entity will include for instance the movements of neutrinos within the interior of the entity as they pass through. A revision is contemplated which would define the history of an entity as the sum of processes in which that entity is the major participant. The relation between a material entity and its history should be one-to-one. Relation of boundary-dependence for occurrents BFO 2.0 Draft Document 35 a is boundary_dependent_on b = Def. a and b are occurrents & a temporal_part of b at t & a is necessarily such that it cannot exist unless either (b exists or there exists some temporal_part of b which includes a as temporal_part) The missing ‘at t’ here signifies that this is a relation between occurrents Process p is a process = Def. a is an occurrent that has temporal proper parts and s-depends on one or more material entities. Examples: the life of an organism, the process of sleeping, the process of cell-division, a beating of the heart, the process of meiosis, the course of a disease, the flight of a bird, the process of aging. Just as there are relational qualities so also there are relational processes, which s-depend on multiple material entities as their relata. Examples: John thinking about Mary [3,4], John worrying about Mary, a moving body causing another body to move. Process boundary p is a process boundary = Def. p is an occurrent entity which separates one process from another immediately succeeding process & occupies a zero-dimensional temporal region. Example: the boundary between the 2nd and 3rd year of your life. a has_participant b =Def. a is an occurrent & b is a material entity & a s-depends on b. BFO 2.0 Draft Document 36 Process profiles The problem of process qualities In the case of a body moving with a constant speed, we can distinguish at least the following elements: (1) the body (object) that is moving (2) the process of moving (3) the temporal region occupied by this process (4) the spatiotemporal region that is occupied by this process (trajectory of the motion) (5) the determinate speed, a real-number magnitude referred to by means of (6) an expression (information artifact, thus a BFO:generically dependent continuant) such as ‘3.12 m/s’. Items (1)-(4) and (6) correspond directly to readily identifiable BFO categories. In regard to item (5), it has been proposed that BFO recognize a new category of process quality, the counterpart on the occurrent side of qualities of continuants. To see the problems with such an approach, consider the following scenario, which is designed to illustrate the contrasting logico-ontological orders which rule on the continuant (three-dimension) and occurrent (four-dimensional) side of BFO [14, 21, 30, 31, 32, 33]. Imagine, first, an independent continuant, John, an object, who, on a certain day, either does or does not go on a one-month diet. In the former case his weight quality will decrease; in the latter case this quality will remain constant. In either case John will remain at the end of the month the same individual object as he was on the day in question. In the case of a process, in contrast, no parallel scenario is imaginable. This is because there is no way that the process which is John’s life could be imagined to vary under two different scenarios – for example life with diet, life without diet – while remaining one and the same individual process. itself would remain the same individual process. If something varied, then the process itself would be a different process. Why processes do not change BFO 2.0 Draft Document 37 Processes do not change, because processes are changes (they are changes, for example, with certain rates, and happening at certain times and in certain orders). They are changes in those independent continuants which are their participants. The difference in logico-ontological order as between continuants and occurrents is captured in the fact that instance-level parthood and other instance-level relations on the side of continuants, are indexed by time; not however on the side of occurrents. As Galton and Mizoguchi point out [53], persuasive arguments can be found in the literature (e.g., [54, 55, 56, 57]) that events cannot change: The argument is essentially that the event as a whole occupies an interval of time; if in its early stages the event has a certain property which it lacks in its later stages, then it is not the event as a whole which either has the property or lacks it, but rather one part of the event has the property and another part lacks it. Hence […] the event does not change. For continuants, predications may need to be time-indexed in order to be true. For example, if a instantiates larva at t, then it does not follow that a instantiates larva simpliciter. For occurrents, in contrast, instantiation relations always hold simpliciter. This is because, while continuants can change their type from one type to the next (e.g. a fetus becomes an embryo becomes an infant …), occurrents can never change their type from one time to the next. Certainly an occurrent can for example involve parts which are of different sorts in different times. A process of movement can, for example, have speed v1at one time and then have a different speed v2at a later time. But there is then nothing in the realm of occurrents which changes; rather, there is (simpliciter, un-time-indexedly) a process with two different parts. The solution to the problem The treatment we propose rests on the insight that to predicate, for instance, ‘has speed 3.12 m/s’, to a process of motion is to assert not that that the process has a special quality (which the same process, in another conceivably have lacked) but rather that the process in question is of a certain determinate type. The assertion that process p has speed v is thus analogous not to: rabbit r has weight w, but rather to rabbit r instance_of the universal: rabbit. But we can imagine, now, that process p is an instance not only of the universal 3.12 m/s motion process, but also of the universal burning 9.2 calories per minute process, utilizing 30.12 litres of oxygen per kilometer, and so on. (It may also instantiate universals such as: running process, be a BFO 2.0 Draft Document 38 cardiovascular exercise process, and many more.) The proposed solution thus threatens a consequence which conflicts with the BFO rule of thumb that ontologies should as far as possible avoid assertions of relations between universals which imply multiple inheritance [19]. How, then, is BFO to do justice to the need to annotate data in which speed or other putative qualities are ascribed to bodily motions or other processes? The answer lies in the recognition that, when measuring a process, it is in fact always only certain structural dimensions of the corresponding whole processes to which the measurement datum directly relates. In the mentioned case these would include for example structural parts pertaining to velocity of motion, energy consumed, oxygen consumed. We shall in what follows call such structural dimensions process profiles. Structural dimensions of qualities The idea of process profiles as structural dimensions of processes has a counterpart in the world of continuant qualities. Here, familiar, we can distinguish in every color quality instance three dimensions of variation, corresponding to three inseparable color quality parts of hue, brightness and saturation, tied together in a three-sided reciprocal dependence relation. An instance of colour-hue cannot of its nature exist, except as bound up with some instance of brightness and saturation; instances of brightness and saturation, similarly, cannot exist except as bound up with some specific instance of hue [48, 49, 50], yielding a dependence structure of the sort depicted in Figure 5 [1, 2, 20]: Figure 5: Three-sided reciprocal dependence BFO 2.0 Draft Document 39 where a, b, c, are instances of the three universals of hue (), brightness () and saturation (), respectively. Analogous dependence structures are found also in other sensory domains, for example in the three-sided reciprocal dependence of the pitch, timbre and loudness which are the three structural dimensions of a tone, and similar analyses can be used to describe the structures of cognitive and linguistic acts of a range of different sorts [4, 58, 59]. To say that there are three dimensions of variation within each instance of color or tone is to assert means that each such instance includes three structural parts – ‘structural’ in the sense that the parts in question cannot exist except in the context of some whole of the given sort, including those other structural parts upon which they are reciprocally dependent. Process profiles are parts of processes, but they are parts not in the sense of ‘pieces’ (separable parts), but rather in the sense of inseparable structural parts. They are entities which cannot exist except in the content of a surrounding whole of this given sort. They are inseparable in the sense that, for example, for any given instance of your heart functioning as a pump, the relevant motion and auditory profiles would necessarily be associated with some determinate blood output profile. There are, now, analogous structural dimensions of processes, which we call ‘process profiles’. The idea is that for processes of each given sort, for example of bodily motion or of human metabolism, there is a repertoire of such process profiles, and it is entities of this sort to which many of the assertions we make about processes are directed. This idea has been advanced already under a different terminology in the studies referenced in [50] on the variables encoded in physiology models used in the study of physiological processes and represented in biophysical measurement data. Two particularly important process profiles are those of respiration rate and pulse rate, as documented in the Vital Sign Ontology. Bruno’s diary of weight gain and loss data represents a quantitative process profile of Bruno’s dieting process. Some examples of quantitative (measurable) process profile types, with subtypes provide for illustrative purposes, include: four-dimensional process shape profile (trajectory) velocity profile constant velocity profile 2 mph constant velocity profile BFO 2.0 Draft Document 40 3 mph constant velocity profile increasing velocity profile acceleration profile constant velocity profile 0 ft/s2 acceleration profile 32ft/s2 acceleration profile 33 ft/s2 acceleration profile increasing acceleration profile The types and subtypes here are analogous to the types and subtypes of qualities recognized by BFOconformant ontologies on the continuant side, for example: length 6 cm length 7 cm length The user must however bear in mind, in both sets of cases, the subtypes in question, while they need to be formulated using a specific unit of measure, are in fact unit-specification independent. There are also non-quantitative process profiles, such as auditory process profiles (for example that part of a given process of a heart’s beating which is audible (detectible by a given auditory monitoring device)). More subtle examples of non-quantitative process profiles are provided by those cases where symbologies exist for the recording of (the corresponding structural dimensions of) processes of given sorts, for instance the profile of a chess game as captured in one or other of the standard chess notations, is a process profile in the sense intended here, as also is the choreography profile of a dance as captured in one or other of the standard choreographic notations. Process profiles in human development are identified in the Anatomical Transformation Abstraction (ATA) of the Foundational Model of Anatomy, which represents the ‘time-dependent morphological transformations of the entities represented in the taxonomy during the human life cycle’ from prenatal development to post-natal growth and aging’ [43]. BFO 2.0 Draft Document 41 As we shall see, it is process profiles, not the circumcluding whole process, which instantiate the corresponding (3.12 m/s, 9.2 calories/minute) universals represented in many different sorts of process measurement data. Thus while quantitative values, and units of measure, are associated directly with process profiles, but with the relevant whole processes only in a secondary sense. Four-dimensional process shapes Just as universals in general can be relatively determinable (as in the case of color) or determinate (as in the case of orange of specific hue rgb(204, 90, 64), so also we can distinguish determinable and determinate process profile universals. As Johansson pointed out in his [42], processes involving motion or change of shape or size – any given instance of your walking, for example – must have a certain determinable 4-dimensional process shape. But which determinate shape is instantiated will of course vary from instance to instance. Your specific process of walking is not itself an instance of the universal four-dimensional process shape. Rather its process shape – this particular instance, the four-dimensional shape profile that belongs to it, and to it alone, as structural part – is an instance of the universal four-dimensional process shape profile. Rates and beat process profiles In the draft Towards a Definition of Rate, we use the beat profile example to provide a preliminary account of one important set of process predications, namely predications of rates to processes, including processes whose rates are changing discontinuously or continuously. The account is intended to apply to all processes with beat process profiles, including not only heart beat processes, but also for example drumming processes, and simple cyclical processes (birthdays, …). Every beating process is a beating process in virtue of its including some beat profile as a structural, organizing process part. In addition to the regular beat profile (where a rate can be assigned in the simplest possible), there is also an increasing beat profile, a decreasing beat profile, an accelerating beat profile, as well as many other types of irregular beat profile, some of which, for example, for example when they are detected in measurements of heart beat processes, may be clinically significant. How to deal with predications of processes Each process profile is an instance-level part of some corresponding whole process. We can define: BFO 2.0 Draft Document 42 a process_profile_of b =Def. a and b are processes & a proper part_of b & there is some process c which is part of b and which is such that a, b and c occupy the same temporal region & a s-depends on c. a is a process profile =Def. for some process b, a process_profile_of b To assert, now, that a beating process has rate 4 bpm, is to assert that there is some beat profile which is a part of this process and which occupies the same temporal interval as this process and which instantiates the determinate universal: 4bpm beat profile. More generally: ‘p has F of value n as measured in unit u’ abbreviates: there is some process profile po such that po part_of p & po occupies the same temporal interval as p & po instance_of the determinable process profile type: F & po instance_of the determinate process profile type: F with magnitude n as measured in unit u. States as Static Process Profiles For many process profile types we can distinguish an associated static (or ‘null’) process profile type. Thus for example a null beat profile is a beat profile in which there are zero beats per interval of time; a null velocity profile is one in which velocity is zero; a null acceleration profile is one in which acceleration is zero, and so on. Processes with null process profiles are often called ‘states’ (state of rest, state of uniform motion, …). ‘States’ are special sorts of processes (they are processes in which, along the relevant dimension, nothing happens). Such states can be highly complex: consider the case in which two equal and opposite dispositions of attraction and repulsion can counterbalance each other – the dispositions are realized but there is no movement. BFO 2.0 Draft Document 43 For every continuant entity there is what we might call its existence profile, which is a process profile which is a part of the history of the entity in question, and which has only one state, called ‘exists’. Summing Process Profiles The auditory process profile of the morse code signal for ‘SOS’ has the following structure: ... – – – ... This is built by summation out of successive basic auditory process profiles of three types, called dots, dashes, and spaces (null auditory process profiles), respectively. Between each dot or dash within a single letter there is a single space; between successive letters there are three spaces. Clearly, the process profiles here can be combined in arbitrary strings. If one morse code string is followed by another, then the auditory process profile of their sum is equal to the sum of their respective auditory process profiles. The heart beating process is the sum of two mutually dependent systolic and diastolic processes (along the lines depicted in Figure 6). BFO 2.0 Draft Document 44 Figure 6: Cardiac Cycle, Left Ventricle There seems to be a general law for process profiles: Given any processes p1, … pn which share a specific type T of process profile and which do not overlap in time: T-process-profile(p1 +…+ pn) = T-process-profile(p1) + … + T-process-profile(pn) Note that, in the morse code and similar cases, summation of process profiles has an exact counterpart in the linear composition of generically dependent information artifacts (alphanumeric strings) on the continuant side. Comparing Qualities and Comparing Process Profiles A further issue that we can now address is that of data involving comparison of process profiles (for example to the effect that one process is quicker, or more intense, or of higher frequency, than that process. He, too, it is useful to begin with the counterpart case on the side of qualities. BFO 2.0 Draft Document 45 For a given determinable quality universal Q, we employ ‘DSU(Q)’ as an abbreviation for ‘the determinate sub-universals of Q’. For example if Q is the quality universal length, then DSU(Q) comprises such determinate quality universals as: 1 cm-length, 1.5 cm-length, 2 cm-length, and so on. Again, quality universals are referred to here in a way that involves specification of a unit of measure; however, the universals themselves are clearly independent of such specification. Since the qualities in DSU(Q) can here be ordered linearly in reflection of the real number measures used to described them, we can define ‘shorter-in-length than’ in terms of ‘less than’ for real numbers. In this sense the structure of DSU(Q) explains how length qualities relate to each other. And now the parallel case on the side of occurrent side can be described as follows. For a given determinable process profile universal P, we employ ‘DSU(P)’ as an abbreviation for ‘the determinate sub-universals of P’. For example if P is the process profile universal regular beat, then DSU(P) comprises such determinate process profile universals as: 1 beat per minute (bpm), 1.5 bpm, 2 bpm, and so on. Again, process profile universals are referred to here in a way that involves specification of a unit of measure; however, the universals themselves are clearly independent of such specification. And again: DSU(P) is ordered linearly, so that there is an isomorphism from DSU(P) to the real numbers, and we can define ‘beats faster than’ accordingly in terms of ‘greater than’ for real numbers, and there is a sense in which the structure of DSU(P) explains how beat processes relate to each other in terms of faster and shorter. Spatiotemporal region Def. An occurrent entity that can be occupied_by a processes . Each spatiotemporal region projects_onto some temporal region. Each spatiotemporal region projects_onto some spatial region at t. The projection relations must be defined in every case in terms of the reference frame employed. BFO 2.0 Draft Document 46 Examples: the spatiotemporal region occupied by a human life, the spatiotemporal region occupied by the development of a cancer tumor, the spatiotemporal setting occupied by a process of cellular meiosis. Temporal region Elucidation. An occurrent entity that is part of time (defined always in relation to some reference frame). A temporal region is an occurrent entity upon which a process can be projected. Zero-dimensional temporal region A temporal boundary of a temporal region. Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death. Synonym: temporal instant. One-dimensional temporal region Example: the temporal region during which a process occurs. continuant independent continuant material entity object fiat object part object aggregate BFO 2.0 Draft Document 47 immaterial entity continuant fiat boundary zero-dimensional continuant fiat boundary one-dimensional continuant fiat boundary two-dimensional continuant fiat boundary site spatial region zero-dimensional region one-dimensional region two-dimensional region three-dimensional region specifically dependent continuant quality relational quality realizable entity role disposition function generically dependent continuant occurrent process process profile process boundary temporal region zero-dimensional temporal region one-dimensional temporal region spatiotemporal region BFO Relations To be dealt with in the next version of this document. References BFO 2.0 Draft Document 48 1. Barry Smith, “Logic, Form and Matter”, Proceedings of the Aristotelian Society, Supplementary Volume 55 (1981), 47–63. 2. Barry Smith and Kevin Mulligan, “Framework for Formal Ontology”, Topoi, 3 (1983), 73– 85. 3. Barry Smith, “Acta cum fundamentis in re”, Dialectica, 38 (1984), 157–178. 4. Kevin Mulligan and Barry Smith, “A Relational Theory of the Act”, Topoi, 5/2 (1986), 115– 130. 5. Barry Smith, “Mereotopology: A Theory of Parts and Boundaries”, Data and Knowledge Engineering, 20 (1996), 287–303. Published version 6. Barry Smith, “On Substances, Accidents and Universals: In Defence of a Constituent Ontology”, Philosophical Papers, 26 (1997), 105–127. 7. Barry Smith and Achille Varzi, “The Niche”, Nous, 33:2 (1999), 198–222. 8. Barry Smith and Achille Varzi, “Fiat and Bona Fide Boundaries”, Philosophy and Phenomenological Research, 60: 2 (March 2000), 401–420. 9. Barry Smith, “Fiat Objects”, Topoi, 20: 2 (September 2001), 131–148. 10. Barry Smith and Achille Varzi, “Surrounding Space: The Ontology of OrganismEnvironment Relations”, Theory in Biosciences, 121 (2002), 139–162. 11. Barry Smith and Berit Brogaard, “A Unified Theory of Truth and Reference”, Logique et Analyse, No. 169-170 (2000, published 2003), 49–93. 12. Barry Smith and David M. Mark, “Do Mountains Exist? Towards an Ontology of Landforms”, Environment and Planning B (Planning and Design), 30(3) (2003), 411–427. 13. Barry Smith and Berit Brogaard, “Sixteen Days”, The Journal of Medicine and Philosophy, 28 (2003), 45–78. 14. Pierre Grenon and Barry Smith, “SNAP and SPAN: Towards Dynamic Spatial Ontology”, Spatial Cognition and Computation, 4: 1 (March 2004), 69–103. 15. Barry Smith and Pierre Grenon, “The Cornucopia of Formal-Ontological Relations”, Dialectica 58: 3 (2004), 279–296. 16. Barry Smith, Werner Ceusters, Bert Klagges, Jacob Köhler, Anand Kumar, Jane Lomax, Chris Mungall, Fabian Neuhaus, Alan Rector and Cornelius Rosse, “Relations in Biomedical Ontologies”, Genome Biology (2005), 6 (5), R46. PMC1175958 17. David P. Hill, Barry Smith, Monica S. McAndrews-Hill, Judith A. Blake, “Gene Ontology Annotations: What they mean and where they come from”, BMC Bioinformatics, 2008; 9(Suppl 5): S2. PMC2367625 18. Thomas Bittner, Maureen Donnelly and Barry Smith, “A Spatio-Temporal Ontology for Geographic Information Integration”, International Journal for Geographical Information Science, 23 (6), 2009, 765-798. BFO 2.0 Draft Document 49 19. Barry Smith and Werner Ceusters, “Ontological Realism as a Methodology for Coordinated Evolution of Scientific Ontologies”, Applied Ontology, 5 (2010), 139–188. PMC3104413 20. Barry Smith and Kevin Mulligan, “Pieces of a Theory”, in Barry Smith (ed.), Parts and Moments. Studies in Logic and Formal Ontology, Munich: Philosophia, 1982, 15–109. 21. Pierre Grenon, Barry Smith and Louis Goldberg, “Biodynamic Ontology: Applying BFO in the Biomedical Domain”, in D. M. Pisanelli (ed.), Ontologies in Medicine: Proceedings of the Workshop on Medical Ontologies, Rome October 2003 (Studies in Health and Technology Informatics, 102 (2004)), Amsterdam: IOS Press, 2004, 20–38. 22. Fabian Neuhaus, Pierre Grenon and Barry Smith, “A Formal Theory of Substances, Qualities, and Universals”, Achille Varzi and Laure Vieu (eds.), Formal Ontology and Information Systems. Proceedings of the Third International Conference (FOIS 2004), Amsterdam: IOS Press, 2004, 49–58. 23. Barry Smith, “The Logic of Biological Classification and the Foundations of Biomedical Ontology”, in Petr Hájek, Luis Valdés-Villanueva and Dag Westerståhl (ed.), Logic, Methodology and Philosophy of Science. Proceedings of the 12th International Conference, London: King’s College Publications, 2005, 505–520. 24. Barry Smith, “Against Fantology”, in Johann C. Marek and Maria E. Reicher (eds.), Experience and Analysis, Vienna: HPT&ÖBV, 2005, 153–170. 25. Barry Smith, Waclaw Kusnierczyk, Daniel Schober, Werner Ceusters, “Towards a Reference Terminology for Ontology Research and Development in the Biomedical Domain”, O. Bodenreider, ed., Proceedings of KR-MED, 2006, 57-66. Also available online at: http://ceurws.org/Vol-222. 26. Robert Arp and Barry Smith, “Function, Role, and Disposition in Basic Formal Ontology”, Proceedings of Bio-Ontologies Workshop (ISMB 2008), Toronto, 45-48. Revised version. 27. Richard H. Scheuermann, Werner Ceusters, and Barry Smith, “Toward an Ontological Treatment of Disease and Diagnosis”, Proceedings of the 2009 AMIA Summit on Translational Bioinformatics, 2009, 116-120. 28. Albert Goldfain, Barry Smith and Lindsay G. Cowell, “Dispositions and the Infectious Disease Ontology”, in Antony Galton and Riichiro Mizoguchi (eds.), Formal Ontology in Information Systems. Proceedings of the Sixth International Conference (FOIS 2010), Amsterdam: IOS Press, 2010, 400-413. 29. Lars Vogt, “Spatio-structural granularity Bioinformatics, Vol. 11, Issue 1, May 2010. of biological material entities”, BMC 30. Pierre Grenon: “Spatio-temporality in Basic Formal Ontology: SNAP and SPAN, UpperLevel Ontology, and Framework for Formalization”, IFOMIS Technical Report, 2003. 31. Pierre Grenon: “BFO in a Nutshell: A Bi-Categorial Axiomatization of BFO and Comparison with DOLCE”, IFOMIS Technical Report, 2003. 32. Pierre Grenon: “Nuts in BFO’s Nutshell: Revisions to the Bi-Categorial Axiomatization of BFO”, IFOMIS Technical Report, 2003. BFO 2.0 Draft Document 50 33. Pierre Grenon, “The Formal Ontology of Spatio-Temporal Reality and its Formalization,” in Foundations and Applications of Spatio-Temporal Reasoning, H. Guesguen, D. Mitra, and J. Renz (eds.), Amsterdam: AAAI Press, 2003, 27-34. 34. Maureen Donnelly, “On parts and holes: the spatial structure of the human body” 35. Thomas Bittner, “Axioms for Parthood and Containment Relations in Bio-Ontologies”, in Hahn, U. (ed.), Proceedings of the First International Workshop on Knowledge Representation in Medicine (KR-Med04), CEUR Workshop Proceedings, vol. 102, 4-11. 36. Thomas Bittner and Maureen Donnelly, “Logical Properties of Foundational Relations in Bio-Ontologies”, Artificial Intelligence in Medicine, 39 (2007), 197-216. ftp 37. Maureen Donnelly, Thomas Bittner and Cornelius Rosse, “A Formal Theory for Spatial Representation and Reasoning in Biomedical Ontologies,” Artificial Intelligence in Medicine, 36 (2006), 1-27. 38. Maureen Donnelly, “Relative Places”, Applied Ontology, 1 (2005), 55-75. ftp 39. Maureen Donnelly, “A Formal Theory for Reasoning about Parthood, Connection, and Location”, Artificial Intelligence, 160 (2004), 145-172. 40. Thomas Bittner and Maureen Donnelly, “A temporal mereology for distinguishing between integral objects and portions of stuff,” in R. Holte and A. Howe (eds.), Proceedings of the Twenty-Second AAAI Conference on Artificial Intelligence (AAAI-07), 287-292. 41. Maureen Donnelly, “Containment Relations in Anatomical Ontologies” in Proceedings of Annual Symposium of the American Medical Informatics Association (AMIA), 2005, 206-10. 42. Ingvar Johansson, “Functions, Function Concepts, and Scales”, The Monist 87 (2004), 96114. 43. Cornelius Rosse and J. L. V. Mejino Jr., “A reference ontology for biomedical informatics: the Foundational Model of Anatomy”, Journal of Biomedical Informatics, 36 (2003), 478500. 44. Cornelius Rosse and J. L. V. Mejino Jr., “The Foundational Model of Anatomy Ontology”, in A. Burger, D. Davidson, and R. Baldock, eds., Anatomy Ontologies for Bioinformatics: Principles and Practice, London: Springer, 2007, 59-117. 45. Bernard Harrison, Form and Content, Oxford: Blackwell, 1973. 46. Peter M. Simons, Parts: A Study in Ontology, Oxford: Oxford University Press, 1987. 47. Roman Ingarden, Man and Value, Munich: Philosophica, 1983. 48. Roberto Casati and Achille Varzi, Holes and Other Superficialities, Cambridge, MA: MIT Press, 1994. 49. Max J. Egenhofer and David M. Mark, “Naive Geography”, in A. U. Frank and W. Kuhn, (eds.), Spatial Information Theory: A Theoretical Basis for GIS, Berlin: Springer-Verlag (Lecture Notes in Computer Sciences No. 988), 1995, 1-15. BFO 2.0 Draft Document 51 50. Bernard de Bono, Robert Hoehndorf, Sarala Wimalaratne, George Gkoutos, and Pierre Grenon, “The RICORDO approach to semantic interoperability for biomedical data and models: strategy, standards and solutions”, BMC Research Notes 2011, 4:313. 51. Kerry Trentelman, Barry Smith, “An Axiomatisation of Basic Formal Ontology with Projection Functions”, Advances in Ontologies, Proceedings of the Sixth Australasian Ontology Workshop, Adelaide, 7 December 2010, Kerry Taylor, Thomas Meyer and Mehmet Orgun (eds.), 2010, Sydney: ACS, 71-80. 52. Roberto Casati and Achille C. Varzi, “Spatial Entities”, in: Oliviero Stock (ed.), Spatial and Temporal Reasoning, Dordrecht: Kluwer, 1997, pp. 73-96. 53. Antony Galton and Riichiro Mizoguchi, “The water falls but the waterfall does not fall: New perspectives on objects, processes and events”, Applied Ontology, 4 (2), 2009, 71-107. 54. F. Dretske, “Can events move?”, Mind, 76:479–92, 1967. 55. D. H. Mellor, Real Time, Cambridge: Cambridge University Press, 1981. 56. P. M. S. Hacker, “Events and objects in space and time”, Mind, 91:1–19, 1982. 57. W. Charlton. Aristotle’s Physics, Books I and II, translated with Introduction and Notes. 58. Barry Smith, “Husserl, Language and the Ontology of the Act”, in D. Buzzetti and M. Ferriani (eds.), Speculative Grammar, Universal Grammar, and Philosophical Analysis of Language, Amsterdam: John Benjamins, 1987, 205–227. 59. Kevin Mulligan, “Promising and Other Social Acts”, in K. Mulligan (ed.), Speech Act and Sachverhalt: Reinach and the Foundations of Realist Phenomenology, Dordrecht/Boston/Lancaster: Nijhoff, 1987, 1–27. BFO 2.0 Draft Document