EASO Collaborating Centres for Obesity Management (COMs) Application Form The Concept Obesity is recognised as a global epidemic and the most prevalent metabolic disease world-wide. However, specialised obesity services are not widely available in Europe and obesity care can therefore vary enormously across European regions. In response to this situation, EASO has developed a network of accredited specialised obesity centres, where the quality and efficacy of the care offered to patients are of the highest standards. Under the EASO Collaborating Centres for Obesity Management (COM) scheme, centres will be accredited in accordance with accepted European and academic guidelines. Our aim is to provide physicians, health-care policy makers and health-care providers with authoritative criteria for the development of Obesity Management Centres across Europe, recognized by national health authorities. Accreditation will be granted for a three year period, after which time re-assessment will be undertaken. For further information, please refer to the EASO COM Criteria Paper (Obes Facts 2011;4:329–333) or visit www.easo.org Who Should Apply? The EASO COM network will include university, public and private clinics. Each centre must comply with clearly defined requirements and work in close collaboration for the better management of all obese patients. Each accredited centre must ensure that the obese and overweight patient is managed by a holistic team of specialists and will receive comprehensive state-of-the-art clinical care. Furthermore, the participating centres, under the umbrella of EASO, will work closely for quality control, data collection and analysis, as well as education and research for the advancement of obesity care and obesity science. Each centre will be expected to: Implement state-of-the art evidence-based care for obese patients Monitor all obesity- related medical conditions and risk factors Provide high quality patient and public information Improve access to care pathways by optimizing referral processes and developing close working between levels of care Develop comprehensive multidisciplinary local collaboration Facilitate, and empower patients to make healthy lifestyle changes: develop therapeutic education Educate staff about treating patients with obesity Encourage development of and support Patient Associations, by sharing experience and expertise Offer or collaborate with preventive care services Promote obesity related knowledge and awareness among the public and health care providers Improve the collaboration interface between clinical researchers and scientists Integrate health care, teaching and research Facilitate clinical research projects Why Should You Apply? Each member centre will be accredited, for a three year period, as having met comprehensive criteria as set out by EASO and according to recognised European management guidelines – and will therefore be recognised as a leading obesity management centre in Europe. Accredited centres will have the opportunity to: contribute to the development of EASO pan-European protocols for the evaluation of obese patients contribute to the development of consensus statements/guidelines on specialised aspects of obesity management contribute to obesity education across Europe participate in an EASO led pan-European scientific/clinical exchange programme participate in EASO facilitated Clinical Trials and Pilot Studies participate in EASO coordinated research projects participate in COM ‘Summit Meetings’ at each ECO (European Congress on Obesity) access and contribute to an EASO pan-European system of data collection and analysis access a web-based COM community where each centre can post job vacancies and highlight the key capabilities and features of the centre EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 How Can You Apply? All interested centres are required to complete the comprehensive application form below, which will be assessed by the EASO OMTF (Obesity Management Task Force) – applications will be assessed twice per year. Thereafter, feedback will be given and where necessary assessment site visits will be conducted. No application fee will be charged. However, for those centres that require an assessment site visit, the applicant centre will be expected to cover the travel and accommodation costs of a maximum of two EASO OMTF members. EASO COM Application Form Oslo University Hospital Name of Institution: Address: Department of Endocrinology, Obesity, and Preventive Medicine P O Box 4956 Nydalen Town/City: 0424 Oslo Country: Norway Website: www.oslo-universitetssykehus.no Lead Contact: Mette Svendsen Registered dietitian Position of Lead Contact: Yes Member of EASO National Association: Telephone: +4723016653 Fax: +4722119975 mesven@ous-hf.no Email: Signature of Lead Contact: 16.12.2011 Date of Submission: EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 EASO COM Requirements General Requirements Number of obese patients seen per annum Number of new obese patients per annum Patients: Outline patient profile and selection procedure. Facility Location: Outline facilities and geographical distribution of sites. Number of massively obese patients (BMI > 40) per annum 5500 consultations 1600 Number of obese children/adolescents seen per annum 8-900 cases 0 Specific cases: rare diseases Yes Is the facility a Centre or Clinic? Centre -within a university hospital Yes -within a general hospital No -within a larger department (internal medicine, endocrinology...) Yes If yes, give details. The Department of Endocrinology, Obesity and Preventive Medicine was established in September 2011 as part of the Oslo University Hospital change process in which several hospitals including Aker, Ullevaal, Rikshospitalet and Radiumhospitalet were united to one hospital. Among nine sections in the Department, the Section of Morbid Obesity and Bariatric Surgery and the Section of Preventive Cardiology offer management of obesity. Presently the Morbid Obesity and Bariatric Surgery and Preventive Cardiology sections are located at two sites. As part of the further development of the united Department, plans are made for a one-site facility. Number of beds dedicated to obesity 8 Number of weekly clinics dedicated to obesity 2 new Outline contacts with pediatric team Children and adolescents are evaluated at the Department of Pediatrics, Oslo University Hospital, until the age of 18 years, and thereafter referred to Preventive Cardiology for further follow-up. Number of MDs in the dept involved in obesity management 8 Staff Specifications: Give overview of all staff involved in the delivery of the Obesity Management service. Are all staff members of the relevant EASO National Association? Links to GPs: Outline Patient Pathway System. Number with IASO SCOPE certification 1 Number of Dieticians 4 Number of Psychologists 1 Number of Physical educators 3 First/second/third referral The Department is the first referral center for general practitioners in Oslo and around Oslo, serving a population of about 2 million. The Section of Morbid Obesity and Bariatric Surgery has been assigned tertiary care responsibilities by the Norwegian South-East Regional Health Authority to treat severely obese patients. After assessments and/or treatment the patients are referred back to their general practitioners. Treatment summaries are sent to referring general practitioners . EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 Links to other Medical Services and Facilities: Outline all relevant systems and structured links. The Department is linked to all relevant services and facilities at the Oslo University Hospital. EASO COM Requirements: Equipment and Tools Appropriate for Obese Patients Tool (Essential) Appropriate cuffs for blood pressure measurement (>34cm) Scales with adequate weight capacity (> 200 kg) Armless chairs, high firm sofas in waiting rooms Wide examination tables Beds for very obese patients >200kg Stretchers adapted to very obese persons Sleep apnoea monitors on site or at affiliated facilities Food frequency questionnaire and/or dietary intake recording and assessment Questionnaires concerning depression, eating attitudes and disorders, physical activity, quality of life (QOL) Access to accredited hormonal and molecular genetics laboratories Access to additional relevant diagnostic procedures adapted to the very obese persons, such as: X-ray Ultrasound CT and NMR Scanning Endoscopy Cardiac and Pulmonary Assessment Nuclear Medicine () Comment () Comment () Comment Tool (Recommended) Pedometers Skinfold calipers Body composition analysis [Bio-impedance, dualenergy X-ray absorptiometry (DEXA)] EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 Indirect calorimetry Tool (Optimal) () Comment Hydrodensitometry Air displacement plethysmography EASO COM Requirements Additional Requirements Treatment Modalities: Outline your Institution’s spectrum of clinically proven treatment options (to include the treatment of complications). The obesity treatment is based on good clinical care according to the policy of the Oslo University Hospital and evidence-based guidelines recommended by the Norwegian Health Department and EASO/OMTF guidelines. The Department has a multi-disciplinary team that includes physicians specialized in obesity, lipidology, endocrinology, cardiology, public health and bariatric surgeons. The Department has assessment and treatment options related to hypertension (24-hours blood pressure measurement), cardiac function (bicycle exercise test, cardiac ultrasound), risk factors for cardiovascular disease (quit smoking therapy, dietary and pharmacological treatment of blood lipids) and management of diabetes. Educational Tools: Outline the educational opportunities and options offered by your Institution. The educational opportunities given in the management of the obese patients include individual and group based multidisciplinary therapy lasting for at least one year, printed materials and e-mail links as well as preoperative courses to prepare for surgery and postoperative follow up courses lasting for five years. In addition the patients are offered pharmacotherapy when indicated, and referral to local or specialized opportunities for organized physical activity. Affiliation with an accredited Bariatric Surgery Centre: Outline the scope and nature of any such affiliations. The Section of Morbid Obesity and Bariatric Surgery is accredited for bariatric surgery and has performed more than 1400 bariatric operations mostly laparascopic gastric bypass, since 2004. The section can perform all kinds of bariatric surgical precedures laparoscopically and is the only center in Norway performing laparoscopic duodenal switch. Bariatric surgery is performed according to the EASO/FSO criteria. Data Collection and Management: Outline your Institution’s data collection and management systems. All patients operated at Morbid Obesity and Bariatric surgery are registrated in a prospective database. In cooperation with the Department of Genetics at the Oslo University Hospital, Preventive Cardiology established a database and biobank including 1000 obese adults as part of a research program. We plan to develop a unified prospective register for management and outcome effects of obesity treatment at the national level together with other obesity management centres in Norway. Education and Training and Research: Outline your Institution’s post-graduate training programmes and Education and training The Section of Morbid Obesity and Bariatric Surgery conducts courses for doctors and nurses from Norway and the rest of the world. About 4-6 courses are held each year with about 15 attendees in each course, mostly EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 research capabilities/projects. from Europe or the Middle East. Preventive Cardiology conducts an annual course in Preventive Cardiology offered to postgraduate physicians. Registered dietitians at the Department are responsible for education of dietitians in obesity management at the University of Oslo. A course in obesity evaluation and treatment is offered every other year. Research The Section of Morbid Obesity and Bariatric surgery participates in many clinical studies and is associated with research groups at the University of Oslo and Bergen, the Sahlgrenska University Hospital in Gothenburg, Sweden, and Imperial College in London to name a few. Since 2004 more than 30 publications have originated from the Department of Morbid Obesity and Bariatric surgery. In 2010 the first doctoral thesis by Dr. Erlend Aasheim was based on work done at the Department of Morbid Obesity and Bariatric surgery. At this time there are three individuals working on their doctoral thesis at the Department. The Preventive Cardiology section participates in many clinical studies as reflected in the publication list, and is associated with research groups at the Institute of Nutrition at the University of Oslo, Sahlgrenska University Hospital in Gothenburg, Sweden and others. Preventive Cardiology has participated in multi-centre studies addressing the efficacy of pharmacological treatment of obesity, hyperlipidemia, hypertension, smoking cessation as well as investigator initialized studies among patients with high metabolic risk. In 2009, Mette Svendsen a registered dietitian at Preventive Cardiology successfully defended her doctoral degree based on work done in obesity treatment conducted at the Preventive Cardiology section. At this time one physician is working with her doctoral thesis. Selected references from Preventive Cardiology last 5 years: 1. 2. 3. 4. 5. 6. 7. 8. 9. Tonstad S. Rimonabant: a cannabinoid receptor blocker for the treatment of metabolic and cardiovascular risk factors. Nutr Metab Cardiovasc Dis 2006; 16: 156-62. Svendsen M, Tonstad S. Accuracy of food intake reporting in obese subjects with metabolic risk factors. Brit J Nutr 2006; 95: 640-9. Tonstad S, Anderssen S, Khoury J, Ose L, Reseland J, Retterstøl L. Weight concerns and beliefs about obesity in the Norwegian population. Scand J Food & Nutrition 2006; 50: 25-9. Tonstad S. Is rimonabant a safe and effective therapy for sustained weight loss and improved cardiometabolic risk factors? Nat Clin Pract Cardiovasc Med 2006; 3: 364-5 (erratum Nat Clin Pract Cardiovasc Med 2006; 3: 520). Rissanen A. Effect of orlistat on weight regain and cardiovascular risk factors following a very-low-energy diet in abdominally obese patients. A 3-year-randomized placebo- controlled study. Diabetes Care 2007; 30: 27-32. Håheim LL, Tonstad S, Hjermann I, Leren P, Holme I. Predictiveness of body mass index for fatal coronary heart disease in men according to length of follow-up: A 21-year prospective cohort study. Scand J Public Health 2007; 35: 4-10. Tonstad S, Sandvik E, Larsen PGL, Thelle D. Gender differences in the prevalence and determinants of the metabolic syndrome in screened subjects at risk for coronary heart disease. Metab Syndr Relat Disord 2007; 5: 174-82. Holme I, Haaheim LL, Sogaard AJ, Lund Larsen PG, Tonstad S. Repeated weight loss is associated with the metabolic syndrome and diabetes: Results of a 28 year re-screening of men in the Oslo Study. Metab Syndr Relat Disord 2007; 5: 127-35. Holme I, Tonstad S, Søgård AJ, Larsen PGL, Håheim LL. Leisure time physical activity in middle age predicts the metabolic EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. syndrome in old age: results of a 28-year follow-up of men in the Oslo Study. BMC Public Health 2007; 7:154. Tonstad S, Retterstøl K, Ose L, Öhman P, Lindberg M, Svensson M. The dual peroxisome proliferator-activated receptor / agonist tesaglitazar further improves the lipid profile in dyslipidaemic subjects treated with atorvastatin. Metabolism 2007; 56: 1285-92. Erondu N, Addy C, Lu K, Mallick M, Musser B, Gantz I, Proietto J, Astrup A, Toubro S, Rissannen AM, Tonstad S, Haynes WG, Gottesdiener KM, Kaufman KD, Amatruda JM, Heymsfield SB. NPY5R antagonism does not augment the weight loss efficacy of orlistat or sibutramine. Obesity 2007; 15: 2027-42. Svendsen M, Blomhoff R, Holme I, Tonstad S. The effect of an increased intake of vegetables and fruit on weight loss, blood pressure and antioxidant defense in subjects with sleep related breathing disorders. Eur J Clin Nutr 2007; 61: 1301-11. Fagerberg B, Schuster H, Birketvedt GS, Tonstad S, Öhman P, Gause-Nilsson I on behalf of the SIR Study Group. Improvement of postprandial lipid handling and glucose tolerance in a non-diabetic population by the dual PPAR/ agonist tesaglitazar. Diab Vasc Dis Res 2007; 4: 174-80. Tonstad S. Identifying obese women most at risk from cardiovascular disease. Int J Obes 2007; 31 (Suppl 2): S19-S25. Svendsen M, Rissanen A, Richelsen B, Rössner S, Hansson F, Tonstad S. Effect of orlistat on eating behavior among participants in a 3-year weight maintenance trial. Obesity 2008; 16: 327-33. Madsen EL, Rissanen A, Bruun JM, Skogstrand K, Tonstad S, Hougaard DM, Richelsen B. Weight loss larger than 10% is needed for general improvement of levels of circulating adiponectin and markers of inflammation in obese subjects. A 3-year weight loss study. Eur J Endocrin 2008; 158: 179-87. Søgaard AJ, Meyer HE, Tonstad S, Håheim LL, Holme I. Weight cycling and risk of forearm fractures. a 28-year follow-up of men in the Oslo Study. Am J Epidemiol 2008; 167: 1005-13. Ellingsen I, Hjerkinn E. M., Seljeflot I, Arnesen H, Tonstad S. Consumption of fruit and berries is inversely associated with carotid atherosclerosis in elderly men. Brit J Nutr 2008; 99:674-81. Erratum in: Br J Nutr. 2008; 99 :697 Schuster H, Fagerberg B, Edwards S, Halmos T, Lopatynski J, Stender S, Birketvedt GS, Tonstad S, Gause-Nilsson I, Halldórsdóttir S, Öhman KP for the SIR Investigators. Tesaglitazar, a dual peroxisome proliferator-activated receptor / agonist, improves apolipoprotein levels in non-diabetic subjects with insulin resistance. Atherosclerosis 2008; 197: 355-62. Jenssen TG, Tonstad S, Claudi T, Midthjell K, Cooper J. The gap between guidelines and practice in the treatment of type 2 diabetes. A nationwide survey in Norway. Diab Res Clin Prac 2008; 80: 314-20 Hustvedt BE, Svendsen M, Løvø A, Ellegaard L, Hallén J, Tonstad S. Validation of ActiReg to measure physical activity and energy expenditure against doubly labelled water in obese persons. Brit J Nutr 2008; 100: 219-26. Dørum A, Tonstad S, Liavaag A, Michelsen TM, Hildrum B, Dahl AA. Bilateral oophorectomy before 50 years of age is significantly associated with the metabolic syndrome and Framingham risk score: a controlled, population-based study. Gynecol Oncol 2008; 109: 377-83. Pollestad Kolsgaard M, Andersen LF, Tonstad S, Brunborg C, Wangensteen T, Joner G. Ethnic differences in metabolic syndrome among overweight and obese children and adolescents: the Oslo Adiposity Intervention Study. Acta Pediatr 2008; 97: 1557-63. Aasen G, Fagertun H, Tonstad S, Halse J. Leg fat mass as measured by dual X-ray absorptiometry (DXA) impacts insulin resistance differently in obese women versus men. Scand J Clin Invest 2009; 69: 181-9 EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 25. Michelsen TM, Pripp AH, Tonstad S, Trope CG, Dorum A. Metabolic syndrome after risk-reducing salpingo-oophorectomy in women with high risk of hereditary breast ovarian cancer. A controlled observational study. Eur J Cancer 2009; 45: 82-9. 26. Svendsen M, Helgeland M, Tonstad S. The long-term influence of orlistat on dietary intake in obese subjects with components of metabolic syndrome. J Hum Nutr Diet 2009; 22: 55-63. 27. Malterud K, Tonstad S. Preventing obesity; challenges and pitfalls for health promotion. Patient Educ Couns 2009; 76: 254-9 28. Wangensteen T, Kolsgaard ML, Mattingsdal M, Joner G, Tonstad S, Undlien D, Retterstol L. Mutations in the melanocortin 4 receptor (MC4R) gene in obese patients in Norway. Exp Clin Endocrinol Diabetes 2009; 117: 266-73 29. Tonstad S, Butler T, Yan R, Fraser GE. Type of vegetarian diet, body weight and prevalence of type 2 diabetes. Diabetes Care 2009; 32: 791-6. 30. Tonstad S. Cigarette smoking, smoking cessation and diabetes. Diabetes Res Clin Pract 2009; 85: 4-13. 31. Liavaag AH, Tonstad S, Pripp AH, Tropé C, Dørum A. Prevalence and determinants of metabolic syndrome and elevated Framingham risk score in epithelial ovarian cancer survivors: a controlled observational study. Int J Gynecol Cancer 2009; 19: 634-40. 32. Kolsgaard MLP, Wangensteen T, Joner G, Brunborg C, Holven K, Aukurst P, Halvorsen B, Tonstad S. Elevated visfatin levels in overweight and obese children and adolescents with metabolic syndrome. Scand J Clin Invest 2009; 69: 858-64. 33. Halvorsen B, Heggen E, Ueland T, Smith C, Sandberg WJ, Damås JK, Otterdal K, Tonstad S, Aukrust K. Treatment with the PPARgamma agonist rosiglitazone down-regulates interleukin-1 receptor antagonist in individuals with metabolic syndrome. Eur J Endocrinol 2010; 162: 267-73. 34. Hampson SE, Tonstad S, Irgens L, Meltzer HM, Vollrath M. Mothers’ negative affectivity during pregnancy and obesogenic food choices for their infants. Int J Obes 2010; 34: 327-31. 35. Aronne LJ, Tonstad S, Moreno M, Gantz I, Erondu N, Suryawanshi S, Molony C, Sieberts SK, Nayee J, Meehan AG, Shapiro D, Heymsfield S, Kaufman KD, Amatruda J. A clinical trial assessing the safety and efficacy of the CB1R inverse agonist taranabant in obese and overweight patients: high-dose study. Int J Obes 2010; 34: 919-35 36. Klemsdal TO, Nerland H, Holme I, Pedersen TR, Tonstad S. Effects of a low-glycemic load diet versus a low-fat diet in subjects with and without the metabolic syndrome. Nutr Metab Cardiovasc Dis 2010; 20: 195-201. 37. Peterson RM, Beeson L, Shulz E, Firek A, De Leon M, Balcazar H, Tonstad S, Cordero-MacIntyre ZR. Impacting obesity and glycemic control using a culturally sensitive diabetes education program in Hispanic patients with type 2 diabetes. International Journal Body Composition Research 2010; 8: 85-94. 38. Vollrath M, Tonstad S, Rothbart MK, Hampson S. Infant temperament is associated with potentially obesogenic diet at 18 months. Int J Pediatr Obes 2010; Epub ahead of print 39. Solaas K, Legry V, Retterstol L, Berg PR, Holven KB, Ferrières J, Amouyel P, Lien S, Romeo J, Valtueña J, Widhalm K, Ruiz JR, Dallongeville J, Tonstad S, Leren, TP Rootwelt H, Halvorsen BL, Nenseter MS, Birkeland KI, Thorsby PM, Meirhaeghe A, Nebb HI. Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe). BMC Medical Genetics 2010, 11:144 40. Svendsen M, Tonstad S. Orlistat after initial dietary/behavioral treatment: changes in body weight and dietary maintenance in subjects with sleep related breathing disorders. Nutr J. 2011 Mar 8;10:21 41. Kolsgaard ML, Joner G, Brunborg C, Anderssen SA, Tonstad S, EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 42. 43. 44. 45. 46. 47. Andersen LF. Reduction in BMI z-score and improvement in cardiometabolic risk factors in obese children and adolescents. The Oslo Adiposity Intervention Study- a hospital/public health nurse combined treatment. BMC Pediatr 2011; 11: 47 Singh P, Haddad E, Tonstad S, Fraser G. Does excess body fat maintained after the seventh decade decrease life expectancy? J Am Geriatr Soc 2011; 59: 1003-11 Norheim OF, Gjelsvik B, Klemsdal TO, Madsen S, Meland E, Narvesen S, Negård A, Njølstad I, Tonstad S, Ulvin F, Wisløff T. Norway’s new principles for primary prevention of cardiovascular disease: age differentiated risk thresholds. BMJ 2011; 342:d3626 doi Tonstad S, Després J-P. Treatment of lipid disorders in obesity. Expert Rev Cardiovasc Ther 2011; 9: 1069-80 Tonstad S, Stewart K, Oda K, Batech M, Herring RP, Fraser GE. Vegetarian diets and incidence of type 2 diabetes. Nutr Metab Cardiovasc Dis 2011 Oct 7 [Epub ahead of print] Karlsen TI, Tveitå EK, Røisli J, Natvig GK, Tonstad S, Hjelmesæth J. The validity of the SF-36 in patients with morbid obesity. Obesity Facts, Accepted Svendsen M, Hustvedt BE, Tonstad S. Physical activity in treatment seeking obese subjects with a high metabolic risk profile. Accepted International Journal Body Composition Research Selected references from Morbid Obesity and Bariatric Surgery last 5 years Søvik TT, Aasheim ET, Taha O, Engstrøm M, Bjørkman S, Kristinsson J, Birkeland K, Mala T, Olbers T. Weight loss, cardiovascular risk factors, and quality of life after gastric bypass and duodenal switch – a randomized trial. Ann Intern Med 2011; 155: 281-191. 2. Pournaras D, Aasheim E, Søvik T, Andrews R, Mahon D, Welbourn R, Olbers T, le Roux CW. Lowering of remission rates of type 2 diabetes after bariatric surgery: impact of the 2009 ADA consensus definitions. Br J Surg 2011; epub ahead of print 3. Ågesen TH, Berg M, Thiis-Evensen E, Nesbakken A, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Lothe RA, Skotheim RI. Transcriptional profiling of early and late onset colorectal cancer identifies potential cancer susceptibility genes. Genes and Immun 2011; epub ahead of print. 4. Hølmebakk T, Solbakken A, Mala T, Nesbakken A. Accuracy of prognostication in patients with incurable abdominal malignancy as assessed by surgeons. Eur J Surg Oncol 2011; 37: 571-5. 5. Hofsø D, Aasheim ET, Søvik T, Jakobsen GS, Johnson LK, Aas AT, Sandbu R, Kristinsson J og Hjelmesæth J. Laparososopisk biliopankreatisk avledning med duodenal omkopling. Tidsskr Nor legeforen 2011: 131: 1887-1892. 6. Schou CF, Søvik T, Aasheim E, Kristinsson J, Mala T. Tidsskr Nor legefore 2011; 131: 1882-1886. 7. Hewitt S, Weidanz F, Westgeest H, Ruza I, Ciferska H, Pasquet F, Salomäki S, Olsen E. Effect of bariatric surgery on sulfur amino acids and glutamate. Eur J Intern Med 2011; 22: 238-40. 8. Aasheim ET, Elshorbagy A, Diep LM, Søvik T, Mala T, ValdiviaGarcia M, Olbers T, Bøhmer T, Birkeland KI, Refsum H. European School of Internal Medicine (ESIM) in Brighton Experiences and reflections. Br J Nutr 2011; May 4: 1-10. 9. Aasheim ET, Søvik TT. Global trends in body-mass index. Lancet 2011; 377: 1916-17. 10. Mala T. Invited Editorial Comment: Self-expanding metallic stents as bridge to surgery in obstructing colorectal cancer. Br J Surg. 2011. 98(2):281 11. Nesbakken A, Kristinsson J, Svindland A, Lunde OC. Endoscopic snare resection followed by laser ablation in the treatment of large, sessile rectal adenomas. Scand J Surg. 2011;100(2):99-104. 1. EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 12. Olstad R, Florholmen J, Svartberg J, Rosenvinge JH, Birketvedt GS. Leptin in the General Population, Differences in Sex Hormones, Blood Lipids, Gender and Life Style Characteristics. The Open Behavioral Science Journal 2011; 5: 8-15. 13. Vangen Skyrud R, Aaseth J, Birketvedt GS. Outpatient multidisiplinary treatment of morbidly obese patients; a two year retrospective study. Open Behavioral Science Journal 2011: Vol 5, page 28-32. 14. Søvik TT, Taha O, Aasheim ET, Engström M, Kristinsson J, Björkman S, Schou CF, Lönroth H, Mala T, Olbers T. Randomized clinical trial of laparoscopic gastric bypass versus duodenal switch for superobesity. Br J Surg 2010; 97: 160-6. 15. Aasheim ET, Frigstad SO, Søvik TT, Birkeland KI, Haukeland JW. Hyperinsulinemic hypoglycemia and liver cirrhosis presenting after duodenal switch: a case report. Surg Obes Relat Dis 2010; 6: 441-3 16. Søvik TT, Irandoust B, Birkeland KI, Aasheim E, Schou CF, Kristinsson J, Mala T.Type 2 diabetes and metabolic syndrome before and after gastric bypass.Tidsskr Nor Legeforen 2010; 130: 1347-50. 17. Mårin P, Birketvedt GS. Cortisol regulation in the metabolic syndrome. A novel therapeutic approach. Imunn, Endoc & Metab. Agents in Med. Chem. 2010, 10 18. Berg M, Danielsen, SA Ahlquist T, Merok M, Ågesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen Ø, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA. DNA sequence profiles of the colorectal cancer critical gene set: KRAS-BRAFPIK3CA-PTEN-TP53 related to age at disease onset. Plos one 2010; 5: e13978 19. Søvik TT, Aasheim ET, Olbers T. Randomized clinical trial of laparoscopic gastric bypass versus laparoscopic duodenal switch for superobesity Br J Surg 2010; 97: (Response to Letter to the Editor) 20. Aasheim ET. The alcohol factor in Wernicke’s encephalopathy post bariatric surgery. Ann Surg 2010; 251: 993–4. 21. Aasheim ET, Hofsø D, Søvik TT. Vitamin supplements after bariatric surgery. Clin Endocrinol 2010; 72: 134-5. 22. Aasheim ET, Björkman S, Søvik TT, Engström M, Hanvold S, Mala T, Olbers T, Bøhmer T. Vitamin status after bariatric surgery: a randomized study of gastric bypass and duodenal switch. Am J Clin Nutr 2009; 90: 15–22. 23. Søvik TT, Aasheim ET, Kristinsson J, Schou CF, Diep LM, Nesbakken A, Mala T. Establishing laparoscopic Roux-en-Y gastric bypass: perioperative outcome and characteristics of the learning curve. Obes Surg 2009; 19: 158–65. 24. Hjelmesæth J, Hofsø D, Aasheim ET, Jenssen T, Moan J Hager H, Røislien J, Bollerslev J. Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese subjects. Cardiovasc Diabetol 2009; 8: 7. 25. Skogøy K, Laurini R, Aasheim ET. Pregnancy shortly after bariatric surgery. Tidsskr Nor Laegeforen 2009; 129: 534–6. 26. Aasheim ET, Hove AB, Bøhmer T. Thiamine assay values: influence of anticoagulants and hemoglobin. Scand J Clin Lab Invest 2009; 69: 460–1. 27. Aasheim ET. Peculiarities of Wernicke encephalopathy after bariatric surgery. Ann Surg 2009; 249: 1066–7. 28. Aasheim T. Wernicke Encephalopathy after bariatric surgery: a systematic review. Ann Surg 2008; 248: 714-720 29. Aasheim E, Søvikk TT, Bakke EF. Night blindness after duodenal switch. Surg Obes Relat Dis 2008; 4: 685-6 30. Aasheim E, Hofsø D, Hjelmesæth J, Birkeland KI, Bøhmer T. Vitamin status in morbidly obese patients: a cross sectional study. Am J Clin Nutr 2008; 87: 362-9. 31. Aasheim E, Hofsø D, Hjelmesæth J, Sandbu R. Peripheral neuropathy and severe malnutrition following duodenal switch. Obes Surg 2008; 18: 1640-43 EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288 32. Aasheim E, Bøhmer T. Low preoperative vitamin levels in morbidly obese patients: a role of systemic inflammation? Surg Obes Relat Dis 2008; 4: 779-80 33. Olsen T, Goll R, Cui G, Husebekk A, Vonen B, Birketvedt GS, Florholmen J.Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis. Scan J Gastroenterol 2007; 42: 1312-20 34. Aasheim E, Mala T, Søvik TT, Kristinsson J, Bøhmer T. Surgical treatment of morbid obesity. Tidsskr Nor Legeforen 2007; 127: 3842 35. Søvik TT, Aasheim E, Kristinsson J, Schou CF, Nesbakken A, Mala T. Surgical treatment of morbid obesity at a regional center. Tidsskr Nor Legeforen 2007; 127: 47-9 36. Birketvedt GS, Drivenes E, Agledahl I, Sundsfjord J, Olstad R, Florholmen JR. Bulimia nervosa – a primary defect in the hypothalamic-pituitary-adrenal axis? Appetite 2006; 46: 164-7 Applications will be evaluated twice per year. The first set of applications will be evaluated by the end of the first quarter of 2012 (January - March) and the deadline for applications to be evaluated in this time period is 31 December 2011. This form should be completed in full and returned to the EASO Secretariat at enquiries@easo.org. EUROPEAN ASSOCIATION FOR THE STUDY OF OBESITY REGISTERED CHARITY NUMBER 1111288