Bio- Genetics: Complete Dominance Name:_______________________Hr:____ Background: Remember back to when we learned about DNA- our chromosomes come in pairs, one from mom and one from dad. In Biology, when we study genetics, we study the science behind the genes (on our chromosomes), how we inherit different genes, and we try to figure out what kinds of variations can occur when our mom and dad’s DNA meet! Today we are going to learn about complete dominance. Sometimes, the gene we get from our mom is different than the gene for the same trait we get from our dad. These variable forms of the same genes are called alleles. When two alleles come together to form a pair of genes for a particular trait, we call this a genotype. Our bodies must then decide, based on the genotype, how to make us look the way we do. Our physical appearance, also called our phenotype, is influenced by the interactions between our varying alleles and genotypes that we get from mom or dad. As you may already be thinking, there are MANY ways these alleles can interact with each other, but for now let’s stick to one of the most basic- complete dominance. With complete dominance, one allele for a trait is completely dominant over other alleles for the same trait. For example: Tongue rolling is a dominant trait. We’ll say that its allele is represented by the letter R. People who cannot roll their tongues have what is called a recessive allele, which we will say is represented by the letter r. So let’s recap: (R)= tongue rolling allele (r)= non-tongue rolling allele If we all need two alleles to make our genotype for the tongue rolling gene, what are the 3 different possible variations of genotypes for this trait? RR, Rr, and rr. These three genotypes (respectively) are called homozygous dominant, heterozygous, and homozygous recessive. (One way to remember this is that “homo-“ means same- with RR and rr, the two alleles, or letters, are the same. “Hetero-“ means different- Rr are two different letters.) With Complete Dominance, again, one allele for the tongue rolling trait is completely dominant over the other allele for the same trait. This means that when it comes to the genotype Rr, even though a person is a carrier for the non-rolling tongue allele, the R for tongue rolling is DOMINANT and so, that person will be a tongue roller anyway. So, people with the genotype RR and Rr will be tongue rollers because they posses at least one dominant allele. People with the genotype rr, will not be able to roll their tongue. NOW, in making genetic predictions for the outcome of a particular mating, it is helpful to follow the "steps" below. 1. Assign letters to represent the genes 2. Determine the parental phenotypes and genotypes. 3. Predict the outcome of a cross between the possible gametes from the two parents. 4. State phenotypic and genotypic ratios present in the offspring. 5. Don’t forget to answer the question within the problem. For example, if we know that 1 parent is a tongue roller and their genotype is Rr and the other parent is a non tongue roller and their genotype is rr, we can calculate the probability of what genotypes their children may have by making a Punnett square: Step 1: R = rolled tongues r= not rolled tongues Step 2: Parents’ phenotypes: Tongue Roller X Non-tongue roller Parent’s genotypes: Rr X rr Step 3: Punnett Square Step 4: Determine Ratios Parent 1 genotype R Genotypic Ratio ½ Rr ½ rr r r Rr rr Parent 2 genotype r Rr rr Phenotypic Ratio ½ rolled tongues ½ not rolled tongues **Inside of the squares are the possible genotypes of the offspring. We can then describe this Punnett square in 2 ways: By Genotype and Phenotype. Each child has a 50% chance of having the heterozygous genotype for tongue rolling and a 50% chance of having the homozygous recessive genotypes are for tongue rolling. Because of complete dominance if the child is heterozygous it will have a phenotype of a tongue roller. If the child is homozygous recessive it will have the phenotype of nontongue rollers. Often times you will be asked to write out the phenotypic and genotypic ratios. In this case you can make a small table such as the one above. Let’s do a practice together! In flowers, red petal color is dominant to white petal color. Please cross a heterozygous red flower with a homozygous red flower. Is it possible to get white flowers from this cross? Show the Punnett square and give the genotypic and phenotypic ratios of the offspring. Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P Bio: Complete Dominance Practice 1: -Show and explain all work- include necessary Punnett squares 1. Based on the information on the previous page, is it possible for 2 parents who are tongue rollers to have a child who is a non-tongue roller? How? Step 2: Parents’ phenotypes: ___________________ x _________________ Step 1: Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 2. Curly hair is dominant over the allele for straight hair. Two parents have curly hair but are heterozygous for the hair trait. Draw the Punnett square for their offspring: Step 2: Parents’ phenotypes: ___________________ x _________________ Step 1: Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P a. What percentage of their children will have straight hair? Curly hair? b. What if one of their heterozygous children married and had children with a person homozygous dominant for curly? Show a Punnett square. What percentage of their children will have curly hair? Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P Bio: Complete Dominance Name:___________________Hr___ Practice 2-Show and explain all work- include necessary Punnett squares 1. In summer squash, white fruit is dominant over yellow. Suppose that a gardener places the pollen from a homozygous yellow-fruited plant on the pistil of a heterozygous white-fruited plant, Determine the genotypic and phenotypic ratios of the possible offspring. What is the probability of getting yellow fruit? Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 2. In humans, polydactyly (extra fingers or toes) is dominant over normal fingers and toes. Please give the genotypes of the following individuals. Cross a heterozygous individual with a homozygous recessive individual. What is the probability of this couple having a polydactyl child? Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 3. Dogs can have spots=S or no spots=s. You have a dog with no spots. Decide if the following statements are true or false: a. Your dog’s genotype is Ss. b. Your dog’s parents could have been spotted. c. Your dog’s parents could have been one with no spots and one with spots. d. Your dog’s parents could both have no spots. e. Your dog’s parents could have been one heterozygous spots and one homozygous spots. If you are ready, you can take your complete dominance quiz now. If you feel you need to work more problems, you can complete practices 3, 4, and/or 5. Bio: Complete Dominance Name:___________________Hr___ Practice 3-Show and explain all work- include necessary Punnett squares 1. You are raising peas from a stock of peas that is always round. You take a round pea and cross it with a heterozygous wrinkled pea. The wrinkled pea’s “parents” had baby peas that always came out with three times as many wrinkles as rounds. a. Is round or wrinkled dominant? b. What is the expected genotypic ratio for the cross you made? Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 2. In peas, yellow seed color is dominant to green seed color. Please cross a homozygous dominant pea plant with a heterozygous pea plant. Show the Punnett square and give the genotypic and phenotypic ratios of the offspring. Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 3. In humans, normal thumbs are dominant over hitchhiker thumbs. Both you and your sister have hitchhiker thumbs, but your mom and dad have normal thumbs. Your brother has a normal thumb, also. Please give the genotypes of the following individuals. (Hint: Set up a Punnett square to help you.) a. your father______ d. your sister_____ b. your mother_____ e. your brother_____ c. you_____ Bio: Complete Dominance Name:___________________Hr___ Practice 4-Show and explain all work- include necessary Punnett squares 1. Short hair is dominant over long hair in rabbits. A homozygous dominant rabbit is mated with a homozygous recessive rabbit. Show the Punnett square and determine the genotypic and phenotypic ratios of the offspring. Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: 2. Step 4: G P In humans, green eyes are dominant over blue eyes. Is it possible for a homozygous dominant male and a heterozygous female to have a blue-eyed child? Step 1: Step 2: Parents’ phenotypes: ___________________ x _________________ Parent’s genotypes: ___________________ x _________________ Step 3: Step 4: G P 3. For cows, the allele for brown fur color is dominant over white fur color. A farmer has 2 cattle to start with: one brown heterozygous male and one brown homozygous dominant female cow. If the farmer wanted ALL WHITE cows, how many generations of inbreeding cows would it take to get a herd of all white cows? (Hint, siblings cannot be bred back to parents because of age difference, but siblings can be bred to siblings). Show all work and punnett squares. Bio: Complete Dominance Name:___________________Hr___ Practice 5-Show and explain all work- include necessary Punnett squares 1. In a particular flower there are big and small blooms. For each of the following statements, tell which trait you think is dominant and why. If you can’t tell which is dominant from the information given, then put “can’t tell.” Use punnett squares to support your answer. a. Two big bloomed flowers have a small bloomed offspring. Are big blooms or small blooms dominant? b. Two big bloomed flowers have all big bloomed offspring. Are big blooms or small blooms dominant? c. A big bloomed flower and a small bloomed flower have ½ big bloomed offspring and ½ small bloomed offspring. Are big blooms or small blooms dominant? d. Two small bloomed flowers have ¾ small bloomed offspring and ¼ big bloomed offspring. Are big blooms or small blooms dominant?