Unit 1 Emergent Properties Learning Log SY16 Lesson 1- Chemistry, Water, Carbon EK 2.a.3 Organisms must exchange matter with the environment to grow, reproduce, and maintain organization Topic Presentation: click here Note: This is a-3 part topic Textbook Resources: Campbell’s Biology: chapters 2, 3, 4 OpenStax Biology: Chapter 2 Biozone Pages: Volume 1: p. 11-13 Supplementary Resources: “Crash Course: Biology” Videos: That's Why Carbon is a Tramp: Biology #1” “Water- Liquid Awesome: Biology #2” Bozeman Science: “Matter”, “Water: A Polar Molecule”, “Acids Bases and pH” Learning Objectives LO 2.6 The student is able to use calculated surface area-to-volume ratios to predict which cell(s) might eliminate wastes or procure nutrients faster by diffusion. [See SP 2.2] LO 2.7 Students will be able to explain how cell size and shape affect the overall rate of nutrient intake and the rate of waste elimination. [See SP 6.2] LO 2.8 The student is able to justify the selection of data regarding the types of molecules that an animal, plant or bacterium will take up as necessary building blocks and excrete as waste products. [See SP 4.1] LO 2.9 The student is able to represent graphically or model quantitatively the exchange of molecules between an organism and its environment, and the subsequent use of these molecules to build new molecules that facilitate dynamic homeostasis, growth and reproduction. [See SP 1.1, 1.4] Part 1: Chemistry Questions to answer: 1. How common are the elements that living systems are made out of? 2. Explain the relationship between matter and energy. 3. Why do atoms bond? 4. What is the cause of molecular polarity? 5. How does the type of bonds present in a substance influence the chemical and physical properties of that substance? 6. If the breaking of bonds requires an input of energy (which it always does), how is it possible that some chemical reactions (like the burning of gasoline, for instance) can release energy into the environment? 7. How do the properties of a compound like H2O or NaCl illustrate the concept of emergent properties? 8. Why are radioactive elements useful for the study of biological systems? Things you should make sure you understand: Please ask about these in class ● The periodic location, atomic number, number of valence electrons, and biological utility of S,P,O,N,C,H, along with Ca, K, Na, & Cl. ● How energy interacts with atoms. ● The differences between ionic and covalent bonds. ● How to identify if a substance is covalent (molecular) or ionic. ● Basic differences between covalent and ionic substances ● How to identify if a molecule is polar or non-polar. ● How to determine the intermolecular forces that will exist in a substance. ● The cause of radioactivity. Part 2: Water Questions to answer: 1. Why are living things mostly made of water? 2. Draw a water molecule and indicate its polarity. 3. Explain how the structure of water molecules account for each of the following properties: a. Cohesion b. Adhesion c. High Specific Heat d. Floating Ice e. Good Solvent Properties f. Dissociation of water molecules 4. Explain 1 way that each of the above properties are useful for living systems. 5. Explain the relationship between the dissociation of water and the pH of a particular aqueous solution. Things you should make sure you understand: Please ask about these in class ● The absolute need for water in terrestrial living systems. ● How the properties of water demonstrate the concept of emergence. ● How to determine the pH of a solution if given the concentration of hydronium or hydroxide ions. Part 3: Carbon Questions to answer: 1. Why is carbon central to the structure of all biological molecules? 2. Explain the concept of an isomer. As the number of carbon atoms in a molecule increases, what happens to the number of possible isomers of that molecule? 3. Why is it significant that all biological systems use L-amino acids and D-sugars? 4. Draw each of the following functional groups: a. hydroxyl b. carbonyl (ketone) c. carbonyl (aldehyde) d. carboxyl e. amino f. sulfhydryl g. methyl h. phosphate 5. Why are molecules that contain carboxyl groups acidic? 6. Why are molecules that contain amino groups basic? 7. How large a change to the structure of an organic molecule has to be made for that molecule to have a major difference in its effect on a living system? Things you should make sure you understand: Please ask about these in class ● Why carbon is such a versatile atom. ● The different types of isomers that can exist. ● The properties of all of the functional groups in question #4. Lesson 2: organic macromolecules EK 4.A.1: The subcomponents of biological molecules and their sequence determine the properties of that molecule. Topic Presentation: click here Note: This is a-2 part topic Textbook Reading: Campbells Biology Chapter 5 OpenStax Biology: Chapter 3 Biozone Pages: Volume 1: Part 1- pp. 10, 14, 22-30; Part 2- pp. 15 - 21 Supplementary Resources: “Crash Course: Biology” Videos: Biological Molecules - You Are What You Eat: Biology #3 Bozeman Science: “Biological Molecules”, “The Molecules of Life” Learning Objectives LO 4.1 The student is able to explain the connection between the sequence and the subcomponents of a biological polymer and its properties. [See SP 7.1] LO 4.2 The student is able to refine representations and models to explain how the subcomponents of a biological polymer and their sequence determine the properties of that polymer. [See SP 1.3] LO 4.3 The student is able to use models to predict and justify that changes in the subcomponents of a biological polymer affect the functionality of the molecule. [See SP 6.1, 6.4] Part 1: Background, Carbohydrates, & Lipids Questions to answer: 1. How are macromolecule polymers assembled from monomers? How are they broken down? 2. How can you tell a biological molecule is a carbohydrate? 3. Explain the relationship between monosaccharides, disaccharides, and polysaccharides. 4. Why are starch and glycogen useful as energy storage molecules, while cellulose is useful for structure and support? Why isn’t cellulose easily broken down? 5. How do herbivores solve the problem of cellulose digestion? 6. How can you tell a biological molecule is a lipid? 7. Chemically, what is the difference between a saturated fat and an unsaturated fat? How does this difference affect the properties of the molecules? 8. How are triglycerides, phospholipids, and steroids similar? How do they differ? Things you should make sure you understand: Please ask about these in class ● The chemical differences between the carbohydrates and lipids described in this presentation. ● The roles played by carbohydrates and lipids in biological systems. Part 2: Proteins & Nucleic Acids Questions to answer: 1. Why are proteins the most complex biological molecules? 2. Draw the structure of a general amino acid. Label the carboxyl group, the amino group, and the variable (‘R’) group. 3. Draw the formation of a peptide bond between two amino acids. 4. How does the structure of the ‘R’ group affect the properties of a particular amino acid? 5. Define each of the following levels of protein structure and explain the bonds that contribute to them: a. Primary; Secondary; Tertiary; Quaternary 6. How can the structure of a protein be changed (“denatured”)? 7. Draw a nucleotide. Label the phosphate, sugar, and nitrogenous base. 8. Explain the three major structural differences between RNA and DNA. Things you should make sure you understand: Please ask about these in class ● How the structure of proteins and nucleic acids allow for their biological functions. ● How both protein structure and nucleic acid structure illustrate the concept of emergent properties. ● Why directionality and sequence are crucial for the structure and function of proteins and nucleic acids. ● How nucleic acids and proteins function in storage and expression of biological information. Lesson 3: MEMBRANES EK 2.b.1 Cell membranes are selectively permeable due to their structure. Topic Presentation: click here Textbook Reading: Campbell’s Biology Chapter 7 OpenStax Biology: Chapter 4: Section 4.5 & 4.6; Chapter 5: Section 5.1 Biozone Pages: Volume 1: pp. 42, 43-45 (relevant parts), 46 (relevant parts), 48-49 (relevant parts), 59-63. Supplementary Resources: “Crash Course: Biology” Videos: In Da Club - Membranes & Transport: Biology #5 Bozeman Science: “A Tour of the Cell”, “Cellular Organelles” Learning Objectives LO 2.10 The student is able to use representations and models to pose scientific questions about the properties of cell membranes and selective permeability based on molecular structure. [See SP 1.4, 3.1] LO 2.11 The student is able to construct models that connect the movement of molecules across membranes with membrane structure and function. [See SP 1.1, 7.1, 7.2] Questions to answer: 1. How does the structure of the cytoskeleton contribute to its function? 2. Diagram an individual phosopholipid and a bilayer of phospholipids. Label the hydrophillic head, and hydrophobic tails in both. 3. Explain the Fluid Mosaic model of the cell membrane and describe the functions of the proteins that are embedded in the membrane. 4. Diagram the cell membrane. Label the following parts: lipid bilayer, integral proteins, peripheral proteins, cholesterol, cytoskeleton, extracellular matrix, glycoproteins, and glycolipids. Explain the function of each part of the cell membrane in contributing to the functioning of the cell. 5. If cells can not visually inspect other cells, how do the cells of our immune system know if a particular cell they encounter is part of us or part of another organism? Things you should make sure you understand: Please ask about these in class ● The structure and function of cillia and flagella. ● The structure and functions of the three major components of the cytoskeleton (microfilaments, microtubules, and intermediate filaments). ● Why particular substances will or will not be able to pass through the phospholipid bi-layer of the cell membrane. ● How membrane-protein structure can allow for portions of the protein to be embedded in the membrane AND allow portions to extend in to and out of the cell. ● The structure and function of the cell wall. ● The structure and function of the extracellular matrix. ● The differences in structure and function among the types of intercellular junctions found in cells (tight junctions, gap junctions, desmosomes, and plasmodesmata) Lesson 4- Transport EK 2.b.2 Growth and dynamic homeostasis are maintained by the constant movement of molecules across membranes. Topic Presentation: click here Textbook Reading: Campbell’s Biology Chapter 7- sections 7.3-7.4 OpenStax Biology: Chapter 5: Sections 5.2 - 5.4 Learning Objective LO 2.12 The student is able to use representations and models to analyze situations or solve problems qualitatively and quantitatively to investigate whether dynamic homeostasis is maintained by the active movement of molecules across membranes. [See SP 1.4] Biozone Pages: Volume 1: pp. 63-71. Supplementary Resources: “Crash Course: Biology” Videos: In Da Club - Membranes & Transport: Biology #5 Bozeman Science: “Cell Membranes”, “Transport Across Cell Membranes” Questions to answer: 1. How does the second law of thermodynamics allow for diffusion of substances? 2. How is active transport possible, since it contradicts the tendencies of the second law of thermodynamics? 3. Diagram one complete cycle of the Sodium-Potassium pump. Is this active or passive transport? 4. Is it possible for a solution to be both hypertonic and hypotonic? Why or Why not? 5. How do large molecules get taken in to or removed from the cell? Things you should make sure you understand: Please ask about these in class ● The similarities and differences between simple diffusion, facilitated diffusion, and active transport. ● Where cells get the energy to power active transport. ● The relationship between osmosis and tonicity. ● The adaptive strategies of animal, plant, and protist cells for dealing with the tonicity of their environments. Lesson 5- Domains and Prokaryotic Cellular Organization EK 2.B.3 Eukaryotic cells maintain internal membranes that partition the cell into specialized regions. Topic Presentation: click here Textbook Reading: Campbell’s Biology Chapter 27 Sections- 27.1-27.3, 27.6 OpenStax Biology: Chapter 4: Section 4.1 & 4.2 Learning Objectives LO 2.13 The student is able to explain how internal membranes and organelles contribute to cell functions. [See SP 6.2] LO 2.14 The student is able to use representations and models to describe differences in prokaryotic and eukaryotic cells. [See SP 1.4] Biozone Reading: Volume 1: pp. 295-299 (relevant sections), 301 Supplementary Resources: “Crash Course: Biology” Videos: Unicellular Life- Bacteria, Archea, & Protists: Biology #35 Bozeman Science: “The Three Domains of Life”, “Bacteria”, “Archea”, “Eukarya” Questions to answer: 1. Explain why the prokaryote/eukaryote dividing line represents a fundamental division among organisms. 2. Explain why we can infer that the Universal Common Ancestor of all life on earth was: a. Unicellular b. Heterotrophic c. Used DNA as its genetic material 3. Draw and label a typical prokaryotic cell. Briefly describe the function of each part. 4. In eukaryotic cells, chloroplasts are the site of photosynthesis, and mitochondria are the site of aerobic cellular respiration. How are bacteria able to carry out photosynthesis and aerobic cellular respiration without these organelles? 5. Why do bacteria evolve so much faster than multicellular eukaryotes? 6. Generally speaking, why do antibiotics only affect bacterial cells and not eukaryotic cells? Things you should make sure you understand: Please ask about these in class ● The differences between transformation, transduction, and conjugation, as methods of horizontal transfer of genetic information among bacteria. ● The following modes of nutrition and give examples of organisms that utilize each one: a. chemoheterotrophic nutrition b. photoautotrophic nutrition c. chemoautotrophic nutrition d. photoheterotrophic nutrition ● Why archaea are placed in their own domain of life, even though they have only been known to science since the 1970’s. Lesson 6- Eukaryote Overview and Endomembrane System EK 2.B.3 Eukaryotic cells maintain internal membranes that partition the cell into specialized regions. Topic Presentation: click here Textbook Reading: Campbell’s Biology Chapter 6 OpenStax Biology: Chapter 4: Sections 4.3 & 4.4 Learning Objectives LO 2.13 The student is able to explain how internal membranes and organelles contribute to cell functions. [See SP 6.2] LO 2.14 The student is able to use representations and models to describe differences in prokaryotic and eukaryotic cells. [See SP 1.4] Biozone Pages: Volume 1: pp. 31-33, 36-41, 43-45 (relevant parts), 46 (relevant parts), 47, 48-49 (relevant parts), 50-57. Supplementary Resources: “Crash Course: Biology” Videos: Eukaryopolis-The City of Animal Cells: Biology #4 Plant Cells: Biology #6 Videos By Paul Anderson: “Compartmentalization”, “A Tour of the Cell”, “Cellular Organelles” Questions to answer: 1. Why is the cell theory significant (don’t just state the tenets, explain what it means and why it is a theory)? 2. How does the ratio of a cell’s surface area to volume place upward and downward limits on cell size? 3. How do organelles allow for increased complexity in cells? 4. Draw and label a typical eukaryotic cell. Briefly state the structure and function of the following organelles: a. Nucleus b. Ribosomes (free and bound) c. Endoplasmic reticulum (rough and smooth) d. Golgi Apparatus e. Vesicles 5. Explain how each of the organelles above functions in the endomembrane system. Things you should make sure you understand: Please ask about these in class ● How advances in microscopy led to advances in cytology. ● The benefits and disadvantages of light microscopy and electron microscopy. ● How the information system of cells (DNA->RNA -> Protein) allows for cells to accomplish all physiological processes Lesson 7- Matter & Energy Processing EK 4.A.2: The structure and function of subcellular components, and their interactions, provide essential cellular processes. Topic Presentation: click here Textbook Reading: Campbell’s Biology Chapter 6 Sections- 6.4-6.5 OpenStax Biology: Chapter 4: Section 4.3 & 4.4 Biozone Pages: Volume 1: 43-45 (relevant parts), 46 (relevant parts), 4849 (relevant parts) Supplementary Resources: “Crash Course: Biology” Videos: Eukaryopolis-The City of Animal Cells: Biology #4 Plant Cells: Biology #6 Bozeman Science: “Compartmentalization”, “A Tour of the Cell”, “Cellular Organelles” Learning Objectives LO 4.4 The student is able to make a prediction about the interactions of subcellular organelles. [See SP 6.4] LO 4.5 The student is able to construct explanations based on scientific evidence as to how interactions of subcellular structures provide essential functions. [See SP 6.2] LO 4.6 The student is able to use representations and models to analyze situations qualitatively to describe how interactions of subcellular structures, which possess specialized functions, provide essential functions. [See SP 1.4] Questions to answer: 1. Explain why cells can’t “make energy”? 2. How is the structure of a lysosome related to its function? 3. Explain one normal function of lysosomes in a multicellular organism and one abnormal function. 4. Explain the functions of vacuoles and explain how they differ between plant cells and animal cells. 5. Draw a mitochondria. Label the matrix, cristae, inner membrane, outer membrane and intermembrane space. 6. Draw a chloroplast. Label the stroma, thylakoids, grana, outer membrane, inner membrane, and where chlorophyll can be found. Things you should make sure you understand: Please ask about these in class ● Why cells require energy, and how they acquire it. ● The different roles of glucose and ATP in cellular systems. ● Why mitochondria and chloroplasts are separate from the endomembrane system, and are considered “semiautonomous” organelles. ● The relationship between the processes that occur in the mitochondria and the processes that occur in the chloroplast. Lesson 8: Adult v. Fetal Hemoglobin Enduring Understanding 4.C: Naturally occurring diversity among and between components within biological systems affects interactions with the environment. Essential Knowledge 4.C.1: Variation in molecular units provides cells with a wider range of functions. Learning Objectives LO 4.22 The student is able to construct explanations based on evidence of how variation in molecular units provides cells with a wider range of functions. [See SP 6.2] Resources: Presentation: click here Textbook Reading Campbell’s Biology- Ch. 5 Open Stax Biology- 4: Section 4.5 & 4.6, Chapter 5: Section 5.1 Biozone Volume pp. 42, 43-45 (relevant parts), 46 (relevant parts), 48-49 (relevant parts), 59-63 Supplementary Resources: “Crash Course: Biology” Videos: In Da Club - Membranes & Transport: Biology #5 Videos from Bozemanscience: “A Tour of the Cell”, “Cellular Organelles” Questions to answer 1. How does the structure of the cytoskeleton contribute to its function? 2. Diagram an individual phosopholipid and a bilayer of phospholipids. Label the hydrophillic head, and hydrophobic tails in both. 3. Explain the Fluid Mosaic model of the cell membrane and describe the functions of the proteins that are embedded in the membrane. 4. Diagram the cell membrane. Label the following parts: lipid bilayer, integral proteins, peripheral proteins, cholesterol, cytoskeleton, extracellular matrix, glycoproteins, glycolipids. Explain the function of each part of the cell membrane in contributing to the functioning of the cell. 5. If cells can not visually inspect other cells, how do the cells of our immune system know if a particular cell they encounter is part of us or part of another organism? Things you should make sure you understand: (PLEASE ask questions about them in class) The structure and function of cilia and flagella. The structure and functions of the three major components of the cytoskeleton (microfilaments, microtubules, and intermediate filaments). Why particular substances will or will not be able to pass through the phospholipid bi-layer of the cell membrane. How membrane-protein structure can allow for portions of the protein to be embedded in the membrane AND allow portions to extend in to and out of the cell. The structure and function of the cell wall. The structure and function of the extracellular matrix. The differences in structure and function among the types of intercellular junctions found in cells (tight junctions, gap junctions, desmosomes, and plasmodesmata)