Faculty of Medicine & Dentistry School News: Social and Community Medicine Amy Green, John Potokar, Claire Durant and Maria Barnes grant award 24 November 2014 Improving healthcare for survivors and perpetrators of domestic violence and abuse 19 November 2014 Healthcare professionals, researchers and survivors of domestic violence and abuse (DVA) are meeting today [19 November] at a conference in Bristol to discuss the findings of a five-year research programme, the largest of its kind in the UK. Perinatal mental health crucial for physical and mental wellbeing of both parents and child14 November 2014 The importance of looking after the mental health of parents during pregnancy and after childbirth, in order to promote the physical and mental wellbeing of both parents and child, is highlighted in The Lancet today. Could walking to work help fix the nation’s health woes? 13 November 2014 Businesses will be encouraging their workers to walk to work as part of a new £1 million trial which gets underway this month. Trial evaluates new laser operation for prostate surgery 10 November 2014 A £1.2 million trial to evaluate the use of new laser technology for benign prostate surgery – one of the most common operations performed on the NHS - is underway in Bristol. Thinking about our futures: festival puts society in the spotlight 27 October 2014 Who has access to your health records? What do women want from the general election? Can Britain handle the threat of international terrorism? These are some of the hot topics being debated at a thought-provoking series of events across Bristol next month. New Dean of Health Sciences 23 October 2014 Professor Jonathan Sandy, currently Interim Dean of Medicine and Dentistry, has been appointed Dean of the Faculty of Health Sciences, which will take effect from 1 August 2015. Teenage self-harm linked to problems in later life 22 October 2014 Those who self-harm as teenagers are more at risk of developing mental health and substance misuse problems as adults, new research from the biggest study of its kind in the UK has revealed. Could technology transform GP consultations? 20 October 2014 The way we interact with our GPs could be transformed thanks to a new £458,000 project exploring whether consultations could viably be conducted via email, text message, telephone or via the internet. New meningitis vaccine only cost-effective at low price 10 October 2014 The ideal cost per dose for a new meningitis vaccine ranges from £3 up to a possible £22 only if several vaccine favourable factors all coincide, according to research which has analysed how to maximise the reduction in cases while making a new vaccination programme cost-effective. RCGP Research Paper of the Year Award prize 9 October 2014 Rachel Dommett, Theresa Redaniel, Mike Stevens, Richard Martin and Willie Hamilton won a category prize in the 2013 RCGP Research Paper of the Year Award for their research paper entitled “Risk of childhood cancer with symptoms in primary care: a population-based casecontrol study,” published in the British Journal of General Practice. In their paper, 12 features of childhood cancers were identified, each of which increased the risk of cancer at least tenfold. These symptoms, particularly when combined with multiple consultations, warrant careful evaluation in general practice. Simple blood test could be used as tool for early cancer diagnosis 25 September 2014 High levels of calcium in blood, a condition known as hypercalcaemia, can be used by GPs as an early indication of certain types of cancer, according to a study by researchers from the universities of Bristol and Exeter. University collaborates with At-Bristol on innovative Brain Lab workshops 22 September 2014 At-Bristol Science Centre, in collaboration with the University of Bristol, has been awarded a grant from the Wellcome Trust, in a UK first to lead an innovative and immersive series of workshops, using real human brain tissue to stimulate discussion about the social, ethical and legal issues around neuroscience and neuroscience research. Gene variant that dramatically reduces ‘bad’ lipids 16 September 2014 Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. How learning to talk is in the genes 16 September 2014 Researchers have found evidence that genetic factors may contribute to the development of language during infancy. Binge drinking in pregnancy can affect child’s mental health and school results 11 September 2014 Binge drinking during pregnancy can increase the risk of mental health problems - particularly hyperactivity and inattention - in children aged 11 and can have a negative effect on their school examination results, according to new research. HIV survival boost for South African patients 11 September 2014 South Africans with HIV have chances of remaining alive after two years on antiretroviral therapy (ART) that are comparable to those of North American patients, provided that therapy is started promptly, according to new research published today in PLOS Medicine. One in five child deaths in England preventable 5 September 2014 Child deaths have fallen to very low rates in all industrialised countries, but many deaths in children and adolescents are still potentially preventable, and much more could be done to cut future deaths, according to a new three-part series on child deaths in high-income countries, published in The Lancet. The Bluebelle Study: Undressing wound infections 28 August 2014 Wound infections are a common complication of surgical procedures, and contribute major costs for the NHS as well as pain, discomfort and inconvenience for patients. A new study will examine whether a main trial comparing wound dressings with no dressings is possible and whether dressings are effective in reducing infection and helping surgical wounds to heal. Fighting prostate cancer with a tomato-rich diet 27 August 2014 Men who eat over 10 portions a week of tomatoes have an 18 per cent lower risk of developing prostate cancer, new research suggests. Combatting childhood obesity from the age of two 11 August 2014 A successful American initiative to tackle childhood obesity will be trialled in the UK, thanks to a new £431,495 research project targeting children as young as two. International Journal of Epidemiology tops the Impact Factor Ratings 7 August 2014The 2013 impact factor ratings released on the 30th July (ISI Web of Science Journal Citation Reports) sees the International Journal of Epidemiology (IJE) at the top of its field – Number one out of a field of 160 journals. Five Bristol scientists named among “the world’s leading scientific minds” 6 August 2014 Five University of Bristol academics have been named by Thomson Reuters as among the top one per cent of scientists who are “the world’s leading scientific minds” and whose publications are among the most influential in their fields. Primary care telephone triage does not save money or reduce practice workload 4 August 2014 Demand for general practice appointments is rising rapidly, and in an attempt to deal with this, many practices have introduced systems of telephone triage. Patients are phoned by a doctor or nurse who either manages the problem on the phone, or agrees with the patient whether and how urgently they need to be seen. National Institute of Health Research Public Health Research Programme Award 30 July 2014 Dr Ruth Kipping and colleagues have been awarded £431,495 by the National Institute of Health Research Public Health Research Programme to undertake a feasibility cluster randomised controlled trial in child care settings New research to tackle treatment for lung disease 29 July 2014 Research into improving treatment for patients with one of the UK’s most common respiratory diseases has received a £810,000 funding boost. New promotions/progressions in SSCM 23 July 2014 Richard Huxtable has been appointed Professor of Medical Ethics and Law. Sarah Purdy has been appointed as Professor of Primary Care. Congratulations to them for this well-deserved recognition of their outstanding achievements. Congratulations are also due to Pete Blair and Nicky Welton on their promotion to Reader, and to Laura Howe on her promotion to Senior Research Fellow. School scheme unable to boost healthy eating and activity among children 17 July 2014 A school-based scheme to encourage children to eat healthily and be active has had little effect, conclude researchers in a study published on bmj.com today. Approval of prison modelling study 17 July 2014 Gilead Sciences has approved a research proposal at the School of Social and Community Medicine, University of Bristol. The investigator-sponsored research proposal is entitled "The impact and cost-effectiveness of HCV treatment in prison in the DAA era: modelling analyses in England and Scotland". Sir Henry Dale Fellowship awarded 17 July 2014 GRANT AWARDS Pl Project title Funder Award date Amount Dr Peter Vickerman HIV Modelling Consortium Bill & Melinda Gates Foundation 14/07/2014 90622 Mr Angus Mcnair Starter Grants for Clinical Lecturers: The DISCLOSE study Academy of Medical Sciences 15/07/2014 19870 Dr Jeremy Horwood Health Checks NSPCR 2014 NIHR - NSPCR Tranche II 18/07/2014 49679 Prof Matthew Hickman Evaluation of interventions designed to increase diagnosis and treatment of patients with hepatitis C virus infection in primary care and drug treatment settings NIHR-PRP 29/07/2014 471480 Dr Nicky Welton (UOB) NMA for Pharmacometrics and Drug-Development MRC 30/07/2014 196566 Dr Nicky Welton HTA Project 14/141/01: FINAL Costs - AF Screening (April 2014) NIHR-HTA 30/07/2014 163037 Prof Alan Emond Centre for Children's Burns Research The Healing Foundation 08/08/2014 200000 Prof Matthew Hickman Revised: 'Excessive drinking and alcohol related harms in Adulthood: ALSPAC at 24 MR/L022206/1' MRC 14/08/2014 1378535 Prof Peter Fleming Neonatal hearing Screening and the risk of Sudden Infant Death Syndrome (SIDS) Lullaby Trust 02/09/2014 44030 Prof Matthew Hickman Final Costs: DrinkThink - Alcohol Screening and Brief Intervention Evaluation NIHR - SPHR 03/09/2014 175027 Dr Frank De Vocht Cancer Mortality & Incidence in the British Rubber Industry - A 45-Year Follow-Up Cancer Research UK 05/09/2014 151868 Mr Andrew Boyd BIS - HE Successful Entry Study CFE Research 11/09/2014 14081 Dr John Potokar 'Living with Inflammatory Bowel Disease' Research Award 2014: 'Sleep disturbance in patients with inflammatory bowel disease' Crohn's & Colitis UK 15/09/2014 19288 Prof Jenny Donovan UK Full Randomised Controlled Trial of Arthroscopic Surgery for Hip Impingement versus best coNventional Care (UK FASHIoN) via Warwick NIHR HTA 18/09/2014 25093 Dr Lesley Wye Researchers in residence NIHR 01/10/2014 52459 Dr Sean Cowlishaw The Role of Army Reservists: An Analysis of their Experiences and the Attitudes and Perceptions of Civilian Employers, Regulars and Significant Others ESRC 09/10/2014 10257 Pl Project title Funder Award date Amount Dr Sofia Dias NIRG: Bayesian evidence synthesis of multiple outcomes MRC 16/10/2014 323624 Dr Peter Vickerman Systematic review of the synergism between OST and ART and modelling the implications for the impact of OST and ART on HIV transmission amongst people who inject drugs (PWID) Aids Alliance 30/10/2014 42639 Prof Rona Campbell OAFI: The Filter FE Challenge: Pilot trial and process evaluation of a multi-level smoking prevention intervention in further education settings NIHR - PHR 11/07/2014 Dr Peter Vickerman Revised SILCS Cost-Effectiveness Analysis - Scope of Work: Phase 2 - June 2014 to December 2015 PATH 15/07/2014 Prof Alastair Hay Childrens drops for ear pain in acute otitis media: the CEDAR randomised controlled trial 2014 (BRTC) NIHR HTA 16/07/2014 Dr Rebecca Barnes OAFI: Testing the feasibility of a consultation-level intervention for frequent attenders with clinically inexplicable symptoms in primary care NIHR - RFPB 18/07/2014 Dr Natasha Martin The impact and cost-effectiveness of HCV treatment in prison in the DAA era: modelling analyses in England and Scotland Gilead Sciences Inc 21/07/2014 Dr Matthew Ridd HTA: The BEEP Trial - A Randomised Controlled Trial to Determine Whether a Skin Barrier Enhancement with Emollients Can Prevent Eczema in High Risk Children NIHR HTA 22/07/2014 Dr Elsa Marques OAFI: The choice between hip prosthetic bearing surfaces in total hip replacement: evidence synthesis, statistical analysis and decision modelling to evaluate the effectiveness and cost-effectiveness of prosthetic implants for the NHS NIHR - RFPB 25/07/2014 Prof Matthew Hickman Amendment #1: Evaluating the impact of opiate substitution treatment on drug related deaths in the population: a natural experiment using primary care, other drug treatment databases & model projections NIHR 29/07/2014 Dr Frank De Vocht Year 2: Cancer Mortality & Incidence in the British Rubber Industry - A 45-Year FollowUp Cancer Research UK 10/09/2014 Pl Project title Funder Award date Prof Chris Salisbury OAFI - The potential of alternatives to face to face consultation in general practice, and the impact on different patient groups NIHR HS&DR 16/09/2014 Prof Richard Martin YEAR 4: Breastfeeding promotion trial and adolescent IQ and lung function National Institutes of Health 29/09/2014 Dr Frank De Vocht Creation of a quantitative historical jobexposure matrix for plutonium workers and feasibility of its use with reconstructed occupational histories for epidemiological purposes NIHR - PRP 27/10/2014 Richard Martin and Caroline Relton; with several coinvestigators across SSCM, the University of Bristol, Manchester University and the International Agency for Research in Cancer in Lyon. CRUK Programme Grant The CRUK have awarded £4.1 million and recognised this as 'an ambitious programme with potential for high impact'. Reducing the burden of cancer: causal risk factors, mechanistic targets and predictive biomarkers. The programme seeks to strengthen causal inference in cancer epidemiology through the application of Mendelian randomization approaches and the exploration of epigenomic and metabolomic intermediates in 6 types of cancer (lung, prostate, renal, breast, ovarian, and head and neck). The team leading the programme was also recognised by the CRUK as 'being at the cutting edge of developing and deploying Mendelian randomization methodology'. The programme will be affiliated to the MRC Integrative Epidemiology Unit. RECENT FELLOWSHIP SUCCESSES Abigail Fraser – MRC Career Development Fellowship Matthew Ridd – NIHR Postdoctoral Fellowship Dan Lawson – Sir Henry Dale Fellowship Amount £4.1 million