Joint Institute Third Annual Symposium October 9 – 11, 2013 Beijing, China 1 October 9 Wednesday 8:00 – 17:00 JI Concurrent Sessions Session 1: Cardiovascular Diseases (Room 209 of Yifu Teaching Building, PUHSC) Session 2: Lung-Gut Microbiome Diseases (Room 114 of Yifu Teaching Building, PUHSC) Session 3: Liver Diseases (Room 205 of Conference Center, PUHSC) Session 4: Renal Diseases (Peking University First Hospital) 2 18:00-20:30 Joint Institution Welcome Banquet (Invited only) (Vision Hotel Banquet Hall) October 10 Thursday AM Venue Room 209 of Yifu Teaching Building, PUHSC Chair: Professor Weigang Fang, PhD, Vice President, PUHSC 3 8:10 – 8:20 Group Photo 4 8:30 – 8:50 Opening Ceremony Opening Address by: Yang Ke, MD, Executive Vice President, PKU and PUHSC James O. Woolliscroft, MD, Dean, University of Michigan Medical School (UMMS) Qide Han, MD, President, Peking University Health Science Center Vice Chair, Chinese People's Political Consultative Conference 5 8:50 – 9:30 Keynote Speech: Optimizing Institutional Approaches to Enable Research Steven Kunkel, PhD, Senior Associate Dean for Research, UMMS Yangfeng Wu, MD, PhD, Executive Director of Clinical Research Institute, PUHSC 6 9:30 – 11:00 7 Panel Discussion –Advancing Academic Innovations through Technology Transfer and Commercial Partnerships. 9:30 – 9:45 Teri Grieb, PhD, Senior Director for Research, UMMS 9:45 – 10:00 JiaTian, Director, Office of Technology Transfer, PUHSC 10:00 – 10:15 Ray Hutchinson, MD, MS, Associate Dean for Regulatory Affairs, UMMS 10:15 – 10:30 Edward Zhou, MBA, MS, New Horizon Capital 10:30 – 11:00 Panel Discussion 8 11:00 – 11:15 Break 9 11:15 - 11:45 Keynote Speech: Thoughts on Clinical Discipline Development Haiyan Wang, MD, FACP, professor of Medicine at PUHSC First Hospital, President of Peking University Institute of Nephrology 10 11:45 - 12:15 Keynote Speech: Genetic Modifiers and Markers of Liver Disease Bishr Omary, MD, PhD, Professor and Chair, Department of Molecular & Integrative Physiology, UMMS 11 12:15 – 13:30 October 10 LUNCH (Campus Master Inn) Thursday PM Chair: Joseph C. Kolars, Senior Associate Dean for Education and Global Initiatives, UMMS 12 13:30 - 14:50 13 14 13:30-13:50 Plenary Session: Mechanisms of Disease 15 13:50 -14:10 Transcriptome analysis reveals specific CD4 T cell gene signature in rheumatoid arthritis Protection Against Vascular Injury by Enzymatic Dissipation of Intravascular Nucleotides David Pinsky , MD, J. Griswold Ruth M.D. & Margery Hopkins Ruth Professor, Internal Medicine, Professor, Molecular and Integrative Physiology, Chief, Cardiovascular Medicine, Scientific Director, Cardiovascular Center, UMMS Jianping Guo, PhD, Professor, Department of Rheumatology and Immunology, PUHSC Second Hospital 16 14:10 -14:30 DNA Mismatch Repair Dysfunction and Colon Tumor Progression John Carethers, MD, John G. Searle Professor and Chair, Department of Internal Medicine, UMMS 17 14:30 -14:50 Heterogeneous SNVs/INDELs and Reproducible Copy Number Variation Patterns among Single Circulating Tumor Cells of Lung Cancer Patients Jie Wang, PhD, Chief of Department of Thoracic Oncology, Peking University School of Oncology, Beijing Cancer Hospital & Institute for Cancer Research 18 14:50 - 15:20 Panel Discussion 19 15:20 - 15:30 Break 20 15:30 - 17:30 Joint Institute Program Reports 15:30 - 16:00 Pulmonary Program Bei He, MD, FCCP, Director, Pulmonary Division, PUHSC Third Hospital Margaret Gyetko, MD, Senior Associate Dean, Faculty and Faculty Development, Professor of Internal Medicine, UMMS 16:00 - 16:30 Liver Program Lai Wei, MD, PhD, Director and Professor, Peking University Hepatology Institute; Vice President in Charge of Medical Service, Peking University People's Hospital; Director of Beijing Key Laboratory of Hepatitis C and Immunotherapy for Liver Diseases; Chung Owyang, MD, H. Marvin Pollard Professor of Internal Medicine, Professor of Molecular and Integrative Physiology, Chief of Division of Gastroenterology, Director of Pollard Institute for Medical Research, UMMS 16:30 - 17:00 Renal Program Minghui Zhao, MD, PhD, Professor of Medicine, Chief of Renal Division, PUHSC First Hospital, Director of Key Laboratory of Renal Disease, Ministry of Health, Director of Key Laboratory of CKD Prevention and Treatment, Ministry of Education Frank Brosius, MD, Professor of Internal Medicine and Molecular and Integrative Physiology, Chief of Division of Nephrology, UMMS 21 17:15 -17:30 Cardiovascular Program Wei Gao, MD, PhD, Professor and Chair of Cardiovascular Medicine, Vice President, PUHSC Third Hospital Eugene Chen, MD, PhD, Frederick G.L. Huetwell Professor of Cardiovascular Medicine, Professor of Internal Medicine, UMMS 22 18:30 - 20:30 Dinner (Invited only) October 11 Friday 23 8:00 - 14:00 Joint Institute Concurrent Break-out Group Meetings 24 14:00-15:00 Transportation back to PUHSC main campus 25 15:00 - 17:00 Wrap-up Meeting and Closing Remark New Joint Institute Grant Award Reports: 15:00 - 15:15 Towards Molecular Prognosis of Chronic Kidney Disease (CKD) in UMMS and PUHSC Hong Zhang, MD, PhD, Professor of Medicine, Vice-Director of the Renal Division at PUHSC First Hospital. Wenjun Ju, PhD, Research Assistant Professor, Co-Director, Applied Systems Biology Core of George M. O’Brien Kidney Translational Core Center, Department of Internal Medicine, Division of Nephrology, UMMS 15:15–15:30 Imaging Biomarkers for Staging and Assessing Response to Therapy in Multiple Myeloma Wei Guo, MD, PhD, Professor. Chief of Department of Orthopedic Oncology, Director of Bone Tumor Research Laboratory, PUHSC Second Hospital, Chairman of Chinese Musculoskeletal Tumor Society Qian Dong, MD, Associate Professor, Radiology, UMMS 15:30–15:45 Quantitative Measurements of Brain Iron Overload after Intracerebral Hemorrhage Yining Huang, MD, PhD, Chairman and Professor, Department of Neurology, PUHSC First Hospital 15:45 - 16:00 Molecular Mechanisms of Fibrosis and the Progression from Paroxysmal to Persistent Atrial Fibrillation Jihong Guo, MD, PhD, Professor and Associate Director, Department of Cardiology, PUHSC Second Hospital Jose Jalife, MD, Professor of Internal Medicine, Cyrus and Jane Farrehi Professor of Cardiovascular Research, Professor of Molecular & Integrative Physiology, Co-Director, Center for Arrhythmia Research, UMMS 16:00 - 16:15 Particulate Matter Air Pollution and High Density Lipoprotein Dysfunction Jianping Li, MD, PhD, Professor, Vice Chief, Division of Cardiology, PUHSC First Hospital 16:15 - 16:30 Identify Smooth Muscle Cell Specific Protein as Biomarkers for Early Diagnosis of Acute Aortic Dissection Zhe Zhang, MD, Associate Professor, Vice director of Cardiovascular Surgery Department, PUHSC Third Hospital. Bo Yang, MD, PhD, Assistant Professor of Cardiac Surgery, UMMS 16:30 - 17:00 26 Wrap-up Discussion and Closing Remark Team Dinners