The University of Queensland, The School of Medicine, Royal Brisbane and Women’s Hospital, QLD, 4029. Australia Director: Prof Jeffrey Lipman Chair: Dr Jennifer Paratz Research Manager: Dr Sia Athanasas RESEARCH TOPICS Burns and Trauma Management The tyranny of distance, an evaluation of factors impacting on management of trauma patients during transfer to major hospitals. Suitable for Masters or PhD Exercise in patients with burns – psychological health and metabolism – are they interlinked? Suitable for Honours, Masters or PhD An expedited diagnosis of sepsis in burns. Suitable for Honours Inhalation injury post burns – how does this affect right heart function? Suitable for Honours Adrenergic blockade in burns – can this improve outcome? Suitable for Honours Cardiovascular health in patients post burns. Suitable for Honours or Masters. Contact: Dr Jennifer Paratz 3636 1980 j.paratz@uq.edu.au Burns and Trauma Therapy Antibiotic levels in burn – determining optimum antibiotic therapy in burns using microdialysis. Suitable for PhD Wound surface in Operating Room temp and coagulation burn surgery – wound temp is cooler than core temp and believed to impact on continual oozing of wound. Suitable for PhD Pelvic packing – trauma, clinical descriptive study, pelvic fractures cause internal bleeding and so determine if packing prevents deaths. Suitable for PhD Finger escharotomy - does it add anything? Determine if this procedure improves circulation and oxygen diffusion in burns patients. Suitable for Masters or PhD Fluid resuscitation in burns –changes in paradigm due to our previous research ...patients with less fluid resuscitation may be susceptible to renal dysfunction. Suitable for PhD Contact: Assoc. Prof Michael Muller 3636 8314 Michael_Muller@health.qld.gov.au Prof Jeffrey Lipman +61 7 3636 8897 +61 7 3636 3542 j.lipman@uq.edu.au Dr Jennifer Paratz +61 7 3636 1980 +61 7 3636 3542 j.paratz@uq.edu.au Dr Sia Athanasas +61 7 3346 4932 +61 7 3365 5192 s.athanasas@uq.edu.au www2.som.uq.edu.au/som/Research/ResearchCentres/burnstraumacriticalcare The University of Queensland, The School of Medicine, Royal Brisbane and Women’s Hospital, QLD, 4029. Australia Director: Prof Jeffrey Lipman Chair: Dr Jennifer Paratz Research Manager: Dr Sia Athanasas Antibiotic Dosing and Pharmacokinetics in Critical Illness Characterization of in vitro renal replacement therapy models to simulate antibiotic pharmacokinetics in critically ill patients. Suitable for PhD Antibiotic pharmacokinetics and dosing requirements for obese critically ill patients. Suitable for PhD Validation of dosing nomograms for optimising antibiotic prescription in critically ill patients receiving renal replacement therapy. Suitable for PhD Characterising the relationship between antibiotic exposure and bacterial clearance in critically ill patients. Suitable for PhD Antibiotic pharmacokinetics in the initial post injury phase in critically ill trauma patients. Suitable for PhD Cerebrospinal fluid pharmacokinetics of antibiotics in neurosurgical patients. Suitable for PhD Contact: Dr Jason Roberts 36364108 j.roberts2@uq.edu.au General ICU Paracetamol and organ failures Establish feeds → H20 → No H20 Motility agent guidelines Outcomes of Indigenous people in ICU Lines with linkage to infection – retrospective review Do we de-escalate antibiotics? Retrospective review pH/Nitrates in gastric aspirates what does it mean Medical emergency team (MET) database – what are we doing with medical emergency responses, outcome etc When and what problems do we get into with tracheotomies – retrospective review Lung haemorrhage Syndromes in ICU Therapeutic Intervention Elective and bounce backs Asthma management across ICUs Prof Jeffrey Lipman +61 7 3636 8897 +61 7 3636 3542 j.lipman@uq.edu.au Dr Jennifer Paratz +61 7 3636 1980 +61 7 3636 3542 j.paratz@uq.edu.au Dr Sia Athanasas +61 7 3346 4932 +61 7 3365 5192 s.athanasas@uq.edu.au www2.som.uq.edu.au/som/Research/ResearchCentres/burnstraumacriticalcare The University of Queensland, The School of Medicine, Royal Brisbane and Women’s Hospital, QLD, 4029. Australia Director: Prof Jeffrey Lipman Chair: Dr Jennifer Paratz Research Manager: Dr Sia Athanasas Thiopentone and hyperkalaenia Vena Caval filters – incidence, outcome What comes into the ICU that should not – high dependency admission guidelines. How Do We Do Palliative Care Across Centres? Intern experience in the ICU. Bronchoscopy drug levels. Bronchoscopy training for intensivists. PICC line infectious thromboses HFOV and humification Inhaled Heparin study about to commence – to prevent VAP/ARDS Lasix infusions (lasix levels) MVO2 kidney prevent renal contract and mannitol/aminophylline Contrast and how much comes of on CVVHDF – benefit of early dialysis and does it prolong duration of kidney injury? MERT to cath lab – what are they like? Who are the very long stays in ICU – longer than 6 months in ICU – How many – What’s wrong with them – What happens to them. Contact: Assoc. Prof Rob Boots 3636 1849 Rob_Boots@health.qld.gov.au Anaesthesia and Sedation in ICU Dexmedetomidine in critical illness. Suitable for PhD Patient-controlled sedation using dexmedetomidine. Suitable for PhD Dexmedetomidine vs. propofol effects on intracranial pressure & cerebrospinal fluid biomarkers in TBI. Suitable for PhD Analysis of data collected by registered nurse investigators in before/ after study of introduction of a delirium monitoring scale. Suitable for PhD Animal and bench studies investigating field-expedient methods of peritoneal dialysis renal replacement Suitable for MPhil Prof Jeffrey Lipman +61 7 3636 8897 +61 7 3636 3542 j.lipman@uq.edu.au Dr Jennifer Paratz +61 7 3636 1980 +61 7 3636 3542 j.paratz@uq.edu.au Dr Sia Athanasas +61 7 3346 4932 +61 7 3365 5192 s.athanasas@uq.edu.au www2.som.uq.edu.au/som/Research/ResearchCentres/burnstraumacriticalcare The University of Queensland, The School of Medicine, Royal Brisbane and Women’s Hospital, QLD, 4029. Australia Director: Prof Jeffrey Lipman Chair: Dr Jennifer Paratz Research Manager: Dr Sia Athanasas Investigation of the effect of the uremia of acute renal impairment on coagulopathy as measured by thromboelastography. Suitable for MPhil Contact: Prof Michael Reade 3365 5114 m.reade@uq.edu.au Critical Care Endocrinology Plasma and Interstitial Fluid (ISF) levels of hydrocortisone in healthy volunteers randomised to CI or IB. Suitable for PhD Plasma and ISF levels of hydrocortisone in critically ill patients receiving vasopressors randomised to CI or IB. Suitable for PhD Plasma and ISF levels of hydrocortisone in critically ill patients with inflammatory lung disease randomised to CI or IB. Suitable for PhD Contact: Dr Jeremy Cohen Jeremy_Cohen@health.qld.gov.au Prof Jeffrey Lipman +61 7 3636 8897 +61 7 3636 3542 j.lipman@uq.edu.au Dr Jennifer Paratz +61 7 3636 1980 +61 7 3636 3542 j.paratz@uq.edu.au Dr Sia Athanasas +61 7 3346 4932 +61 7 3365 5192 s.athanasas@uq.edu.au www2.som.uq.edu.au/som/Research/ResearchCentres/burnstraumacriticalcare