Mitosis: Spindle Assembly and Function
June 21-26, 2015
Big Sky, Montana USA
Co-Organizers:
Erich A. Nigg
Biozentrum, University of Basel
Basel, Switzerland
Rebecca Heald
University of California-Berkeley
Berkeley, California, USA
Chair Fund Raising:
Jason Swedlow
College of Life Sciences, University of Dundee
Dundee, Scotland, UK
Sunday, June 21, 2015
Time
Title/Topic Event
4:00 p.m. – 9:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 8:15 p.m.
8:15 p.m. – 8:30 p.m.
8:30 p.m. – 9:30 p.m.
Conference Registration
Welcome Reception
DINNER
Welcome from FASEB
Keynote: title t.b.a.
8 February 2016
Speaker, affiliation (or location, if
event)
Tim Mitchison, Harvard Medical School
Monday, June 22, 2015
Time
Title/Topic Event
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
BREAKFAST
Conference Registration
Session 1: Microtubule Dynamics and
Movements in Mitosis
Chromatin regulation of mitosis
9:00 a.m. – 9:30 a.m.
9:30 a.m. – 10:00 a.m.
10:00 a.m. – 10:15 a.m.
10:15 a.m. – 10:45 a.m.
10:45 a.m. – 11:15 a.m.
11:15 a.m. – 11:45 a.m.
11:45 a.m. – 12:00 p.m.
12:15 p.m. – 1:30 p.m.
1:30 p.m. – 4:00 p.m.
4:00 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:45 p.m.
7:00 p.m. – 7:30 p.m.
7:30 p.m. – 8:00 p.m.
8:00 p.m. – 8:15 p.m.
8:15 p.m. – 8:30 p.m.
8:30 p.m. – 8:45 p.m.
8:45 p.m. – 9:15 p.m.
9:15 p.m. – 9:45 p.m.
8 February 2016
Temporal and spatial regulation of anaphase
spindle dynamics by protein phosphatases
Short talk selected from submitted abstracts
Morning Coffee Break
Regulation of Spindle bipolarity by Eg5 and TPX2
Spatial Gradients Regulate Microtubule-based
Motor Activity in Spindle Assembly
Short talk selected from submitted abstracts
LUNCH
Free time
Poster Session 1
Conference Registration
DINNER
Session 2: Systems Biology of Mitosis
Chromosome segregation in live mouse oocytes
and preimplantation embryos
Centrosome form and function in C.elegans
Short talk selected from submitted abstracts
Break
Short talk selected from submitted abstracts
Examining cell division mechanisms using
chemical approaches
The Mechanism of Mitotic Chromosome
Condensation
Speaker, affiliation (or location, if
event)
Chair: Tim Mitchison, Harvard Medical
School
Hironori Funabiki, Rockefeller
University
Francis Barr, University of Oxford
Pat Wadsworth, University of
Massachusetts
Claire Walczak, Indiana University
Chair: Don Cleveland, Ludwig Institute
for Cancer Research, UCSD
Jan Ellenberg, European Molecular
Biology Laboratory (EMBL)
Tony Hyman, Max Planck Institute of
Molecular Cell Biology & Genetics
Tarun Kapoor, Rockefeller University
William Earnshaw, Wellcome Trust
Centre for Cell Biology, University of
Edinburgh
Tuesday, June 23, 2015
Time
Title/Topic Event
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
BREAKFAST
Conference Registration
Session 3: Meiosis and Mitosis in Development
Spindle assembly and orientation in the worm
embryo and mammalian cells
Spindle-dependent and spindle-independent
mechanisms during asymmetric cell division
Short talk selected from submitted abstracts
Morning Coffee Break and
Group Photo
Using C. elegans to dissect mitotic mechanisms
9:00 a.m. – 9:30 a.m.
9:30 a.m. – 10:00 a.m.
10:00 a.m. – 10:15 a.m.
10:15 a.m. – 10:45 a.m.
10:45 a.m. – 11:15 a.m.
11:15 a.m. – 11:45 a.m.
11:45 a.m. – 12:00 p.m.
12:15 p.m. – 1:30 p.m.
1:30 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:45 p.m.
7:00 p.m. – 7:30 p.m.
7:30 p.m. – 8:00 p.m.
8:00 p.m. – 8:15 p.m.
8:15 p.m. – 8:30 p.m.
8:30 p.m. – 8:45 p.m.
8:45 p.m. – 9:15 p.m.
9:15 p.m. – 9:45 p.m.
8 February 2016
Control of chromosome segregation by
acentrosomal spindle in meiosis
Short talk selected from submitted abstracts
LUNCH
Free afternoon (recreational activity)
Conference Registration
DINNER
Session 4: Kinetochore Assembly and Function
Generating a dynamic kinetochore-microtubule
interface
Molecular architecture of vertebrate
kinetochores
Short talk selected from submitted abstracts
Break
Short talk selected from submitted abstracts
Shape and function of kinetochores
Role of geometric constraints in mitotic spindle
assembly
Speaker, affiliation (or location, if
event)
Chair: Renata Basto, Institut Curie
Monica Gotta, University of Geneva
Clemens Cabernard, Biozentrum,
University of Basel
Karen Oegema, Ludwig Institute for
Cancer Research, UCSD
Marie-Hélène Verlhac, Collège de
France
Chair: Angelika Amon, Massachusetts
Institute of Technology (MIT)
Iain Cheeseman, Whitehead Institute
for Biomedical Research
Tatsuo Fukagawa, National Institute of
Genetics
Andrea Musacchio, Max Planck
Institute of Molecular Physiology
Alexey Khodjakov, Wadsworth Center
Wednesday, June 24, 2015
Time a.m. – Time p.m.
Title/Topic Event
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
BREAKFAST
Conference Registration
Session 5: The Mitotic Spindle Checkpoint
9:00 a.m. – 9:30 a.m.
Evolution and function of a regulatory network
for error-free chromosome segregation
Towards a quantitative analysis of the Spindle
Assembly Checkpoint
Short talk selected from submitted abstracts
Morning Coffee Break
Cell fate in response to anti-mitotic
chemotherapeutics
Regulation and Mechanics of Human Mitotic
Kinetochores and Centromeres
Short talk selected from submitted abstracts
LUNCH
Free time
Poster Session 2
Conference Registration
DINNER
Session 6: Centrosomes and Spindle Poles
9:30 a.m. – 10:00 a.m.
10:00 a.m. – 10:15 a.m.
10:15 a.m. – 10:45 a.m.
10:45 a.m. – 11:15 a.m.
11:15 a.m. – 11:45 a.m.
11:45 a.m. – 12:00 p.m.
12:15 p.m. – 1:30 p.m.
1:30 p.m. – 4:00 p.m.
4:00 p.m. – 6:00 p.m.
6:00 p.m. – 7:00 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 9:45 p.m.
7:00 p.m. – 7:30 p.m.
7:30 p.m. – 8:00 p.m.
8:00 p.m. – 8:15 p.m.
8:15 p.m. – 8:30 p.m.
8:30 p.m. – 8:45 p.m.
8:45 p.m. – 9:15 p.m.
9:15 p.m. – 9:45 p.m.
8 February 2016
Investigating the consequences of centrosome
amplification and aneuploidy during
development and their contribution to the
establishment of disease
The link between centrosomes, mitosis and
human developmental diseases
Short talk selected from submitted abstracts
Break
Short talk selected from submitted abstracts
Mechanisms of spindle positioning
Separate but not equal: centrosome segregation
in mitosis
Speaker, affiliation (or location, if
event)
Chair: Karen Oegema, Ludwig Institute
for Cancer Research, UCSD
Geert Kops, University Medical Center
Utrecht
Jonathon Pines, University of
Cambridge, Gurdon Institute
Stephen Taylor, University of
Manchester
Jason Swedlow, The University of
Dundee
Chair: Pat Wadsworth, University of
Massachusetts
Renata Basto, Institut Curie
Fanni Gergely, University of Cambridge,
Cancer Research UK
Pierre Gönczy, ISREC-EPFL Lausanne
Tim Stearns, Stanford University
Thursday, June 25, 2015
Time a.m. – Time p.m.
Title/Topic Event
7:30 a.m. – 9:00 a.m.
7:30 a.m. – 12:00 p.m.
9:00 a.m. – 12:00 p.m.
BREAKFAST
Conference Registration
Session 7: Mitosis Early Career Symposium
9:00 a.m. – 9:30 a.m.
Regulation of microtubule organization and
dynamics by microtubule end-binding proteins
A chemical approach to understanding cell
division
Short talk selected from submitted abstracts
Morning Coffee Break
Chromosome segregation in meiosis: violations
of Mendel's First Law
Business Meeting
LUNCH
Meet the Expert
Session 8: Chromosome Segregation
Substrate recognition and regulation of the
anaphase promoting complex
Motor proteins provide the force balance to
shape and position the mitotic spindle
Short talk selected from submitted abstracts
Break
Short talk selected from submitted abstracts
Biochemical and mechanistic dissection of
condensin complexes
Specific functions of distinct cohesin complexes in
mitosis
Cocktails
DINNER
Party
9:30 a.m. – 10:00 a.m.
10:00 a.m. – 10:15 a.m.
10:15 a.m. – 10:45 a.m.
10:45 a.m. – 11:15 a.m.
11:30 a.m. – 12:15 p.m.
12:15 p.m. – 1:15 p.m.
1:30 p.m. – 2:45 p.m.
3:00 p.m. – 5:45 p.m.
3:00 p.m. – 3:30 p.m.
3:30 p.m. – 4:00 p.m.
4:00 p.m. – 4:15 p.m.
4:15 p.m. – 4:30 p.m.
4:30 p.m. – 4:45 p.m.
4:45 p.m. – 5:15 p.m.
5:15 p.m. – 5:45 p.m.
6:00 p.m. – 7:00 p.m.
7:00 p.m. – 8:30 p.m.
9:00 p.m. – 12:00 a.m.
8 February 2016
Speaker, affiliation (or location, if
event)
Chair: Iain Cheeseman, Whitehead
Institute for Biomedical Research
Anna Akhmanova, Utrecht University
Ulrike Eggert, King's College London
Michael Lampson, University of
Pennsylvania
Claire Walczak, Indiana University
David Barford, Institute of Cancer
Research London, UK
René Medema, Netherlands Cancer
Institute
Tatsuya Hirano, RIKEN
Ana Losada, Spanish National Cancer
Research Centre
Friday, June 26, 2015
Time a.m. – Time p.m.
Title/Topic Event
7:30 a.m. – 8:30 a.m.
8:30 a.m. – 11:30 a.m.
BREAKFAST
Session 9: Chromosome Segregation and
Aneuploidy
8:30 a.m. – 9:00 a.m.
9:00 a.m. – 9:30 a.m.
9:30 a.m. – 9:45 a.m.
9:45 a.m. – 10:00 a.m.
10:00 a.m. – 10:15 a.m.
10:15 a.m. – 10:45 a.m.
10:45 a.m. – 11:15 a.m.
11:15 a.m. – 11:30 a.m.
11:30 a.m.
Speaker, affiliation (or location, if
event)
Chair: William Earnshaw, Wellcome
Trust Centre for Cell Biology, University
of Edinburgh
Consequences of aneuploidy
Angelika Amon, Massachusetts
Institute of Technology (MIT)
How cell division errors shape the cancer genome David Pellman, Harvard Medical School
and Dana-Faber Cancer Institute
Short talk selected from submitted abstracts
Morning Coffee Break
Short talk selected from submitted abstracts
Guarding the genome: signaling in the mitotic
Don Cleveland, Ludwig Institute for
checkpoint
Cancer Research, UCSD
Mechanisms of chromosomal instability in
Duane Compton, Dartmouth Medical
human cancer cells
School
Closing Comments
LUNCH to Go
And DEPARTURES
END OF CONFERENCE
For additional information contact:
FASEB Science Research Conferences
9650 Rockville Pike
Bethesda, MD 20814
www.faseb.org/src
8 February 2016