Module Information For Visiting and Erasmus Students 2014/15 Department* School of Biochemistry & Immunology Background to the School of Biochemistry & Immunology: The School is research Notes intensive and has a strong international reputation for the quality of its scholarly activities. The areas of research in Biochemistry include membrane proteins, enzymology, folic acid biochemistry, structural biology, tRNA biology, neurochemistry, systems biology, cancer biology, molecular parasitology, apoptosis, energy transduction and drug discovery. In the area of Immunology our School is active in immunoregulation, immunomodulation, cell signalling in immunity and inflammation, immunoparasitology, vaccine adjuvant research, innate immunity and inflammation and viral subversion of immunity. Our success in these areas is complemented by our substantial investment in cutting-edge facilities for nuclear magnetic resonance, protein crystallization, X-ray crystallography, transgenics, histochemistry, electron microscopy, confocal microscopy, and fluorescence activated cell sorting. The School has a passion for discovery, an ability to generate new knowledge, expertise in cutting-edge technologies, a flair for entrepreneurship and innovation, as well as a commitment to communicating their passion and knowledge to students. Visiting/Erasmus Full Year Students: If visiting students require a full (60 ECTS) module program then they Module Info on must take the full integrated lecture and practical Biochemistry programme that includes Department BI3110, BI3120, BI3115, BI3015, BI3010, BI3140, BI3125 and a broad curriculum choice. Website One Semester or reduced ECTS students: Those who are not required to participate in a full 60 ECTS programme or who are only in College for one semester can choose to take modified subject modules up to their required number of ECTS from the following; BI3915, BI3925, BI3935*, BI3115, BI3015, BI3415, BI3425*, BI3125 and a broad curriculum choice. *note that BI3935 and BI3425 cannot be selected together. Module Code* Module Name* ECTS Weighting* BI3110 Protein Structure 10 Semester/term Michaelmas taught* Contact Hours* Approx. 60 including practical classes Module Personnel Learning Outcomes Module Learning Aims This module consists of lectures covering proteins and enzymes. In particular lectures focus Module Content/ on protein structure and function, enzyme regulation and enzyme activity. The lectures are Description* complemented by practical classes that explore protein assays, enzyme kinetics and structural biology. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on practical write-ups, and end of year formal Assessment written examinations. Details* *Required fields. Module Code* Module Name* ECTS Weighting* BI3120 Membrane & Cell Biology 10 Semester/term Michaelmas taught* Contact Hours* Approx. 60 including practical classes Module Personnel Learning Outcomes Module Learning Aims This module covers the structure and function of biological membranes, the cytokeleton, Module Content/ signal transduction pathways and associated pathological conditions important to human Description* health that are related to these aspects of cell physiology. These lectures align with practicals that investigate ion transporter function, assays of cAMP signalling, receptor/ligand binding and cell culture techniques. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on practical write-ups, and end of year formal Assessment written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3115 Biochemical Analysis I 5 Semester/term Michaelmas taught* Contact Hours* Approx. 30 hours Module Personnel Learning Outcomes Module Learning Aims This is a practical module that teaches core research skills in general biochemical Module Content/ techniques, maintaining of accurate laboratory records and data, literature evaluation and Description* quantitative problem solving. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on literature skills, quantitative problem solving Assessment abilities and end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3015 Literature Skills 5 Semester/term Michaelmas taught* Contact Hours* Approx. 10 hours Module Personnel Learning Outcomes Module Learning Aims This is a self-directed learning module where students choose a mini-review topic and Module Content/ develop a detailed knowledge on a focused area of biochemical research. Students will be Description* guided in tutorials and the aim of this module is to develop critical thinking, improve general knowledge and enhance writing skills that will prepare students for their final year of undergraduate study and provide broad transferable skills for their future careers. Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed on literature skills and the ability to write a Details* comprehensive review of current scientific literature on a focused topic. Module Code* Module Name* ECTS Weighting* BI3010 Nucleic Acids 10 Semester/term Hilary taught* Contact Hours* Approx. 60 including practical classes Module Personnel Learning Outcomes Module Learning Aims This module consists of lectures covering the structure and function of nucleic acids and the Module Content/ molecular basis of gene regulation, including DNA replication and repair, transcription and Description* translation. Practicals focus on using molecular biology techniques to generate recombinant proteins. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on practical write-ups, and end of year formal Assessment written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3140 Biochemistry in Health & Disease 10 Semester/term Hilary taught* Contact Hours* Approx. 60 including practical classes Module Personnel Learning Outcomes Module Learning Aims This module explores how imbalances in metabolism result in disease. It covers biochemical Module Content/ defence mechanisms against infection and also looks at pharmaceutical drug discovery. Description* Practical classes address aspects of cancer metabolism and evasion of the immune system by tropical parasites. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on practical write-ups, and end of year formal Assessment written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3125 Biochemical Ananlysis II 5 Semester/term Hilary taught* Contact Hours* Approx. 30 hours Module Personnel Learning Outcomes Module Learning Aims This module is a follow on from BI3115 in the first semester and is another practical module Module Content/ that teaches core skills in data manipulation and statistical analysis, as well as problem Description* solving of quantitative problems. Recommended Reading List Module Pre Requisite Module Co Requisite Students taking this module will be assessed on literature skills, quantitative problem solving Assessment abilities and end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3915 Protein Structure 2 5 Semester/term Michaelmas taught* Contact Hours* 30 Module Personnel Learning Outcomes Module Learning Aims This module consists of the same lectures found in BI3110 covering proteins and enzymes, Module Content/ but no practicals. In particular lectures focus on protein structure and function, enzyme Description* regulation and enzyme activity. Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed by end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3925 Membrane & Cell Biology 2 5 Semester/term Michaelmas taught* Contact Hours* 30 Module Personnel Learning Outcomes Module Learning Aims This module consists of the same lectures found in BI3120 covering the structure and Module Content/ function of biological membranes, the cytokeleton, signal transduction pathways and Description* associated pathological conditions important to human health that are related to these aspects of cell physiology. There are no practicals in this modified module. Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed by end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3935 Core Concepts in Immunology 2 5 Semester/term Michaelmas taught* Contact Hours* 30 Module Personnel Learning Outcomes Module Learning Aims This module introduces fundamental processes and molecules associated with the immune Module Content/ system. Immune responses to pathogens, and autoimmunity will be explored. Description* Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed by end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3415 Nucleic Acids 2 5 Semester/term Hilary taught* Contact Hours* 30 Module Personnel Learning Outcomes Module Learning Aims This module consists of the same lectures found in BI3120 covering the structure and Module Content/ function of biological membranes, the cytokeleton, signal transduction pathways and Description* associated pathological conditions important to human health that are related to these aspects of cell physiology. There are no practicals in this modified module. Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed by end of year formal written examinations. Details* Module Code* Module Name* ECTS Weighting* BI3425 Biochemistry in Health and Disease 2 5 Semester/term Hilary taught* Contact Hours* 30 Module Personnel Learning Outcomes Module Learning Aims This module contains the same lectures as BI3140 and explores how imbalances in Module Content/ metabolism result in disease. It covers biochemical defence mechanisms against infection Description* and also looks at pharmaceutical drug discovery. Practical classes address aspects of cancer metabolism and evasion of the immune system by tropical parasites. There are no practicals in this modified module. Recommended Reading List Module Pre Requisite Module Co Requisite Assessment Students taking this module will be assessed by end of year formal written examinations. Details*