UA Flashcards Unit 1 1) Laboratory equipment and other inanimate objects serve as what in the chain of infection? 2) The chain of infection does not includes what? 3) You arrive to work in the clinical laboratory with a small cut on your hand. Your supervisor pulls you from specimen collection (phlebotomy) duties for the day, citing chain of infection protocols. Why is your supervisor concerned about the cut on your hand? 4) Centrifuging an uncapped tube of urine is most likely to produce a/an: 5) What guidelines tells laboratory personnel to consider all patients as possible carriers of blood-borne pathogens? 6) The Centers for Disease Control (CDC) recommends that universal precautions be followed when encountering: 7) What CDC guidelines considers all moist body substances to be potentially infectious and stresses hand washing? 8) The Occupational Exposure to BloodBorne Pathogens Standard is: 9) A laboratory worker who observes a red hand rash after removing gloves should: 10) Plexiglas shields are used in the laboratory when urine tube specimens are being: 11) A urine specimen received in the laboratory is leaking in a transport bag. What is the next course of action? 12) Lab coats worn in the urinalysis lab should: 13) Proper hand washing includes all of the following procedures except: 14) The acceptable method for disposing of urine specimens is: Reservoir 15) Disinfection of the sink in the urinalysis laboratory should be performed: On a daily basis Disinfectant Because you have a point of entry that could expose you to infectious agents Aerosol Standard precautions Specimens containing visible blood Standard precautions A law enforced by Occupational Safety and Health Administration (OSHA) Avoid wearing latex gloves in the future Uncapped for analysis It should be rejected Be completely buttoned Using a paper towel to turn on the water faucet Pouring down the sink followed by copious amounts of water 1 UA Flashcards Unit 1 16) Safety precautions observed in the urinalysis laboratory does not include: 17) The source, method of transmission, and host are all deemed: 18) What is a practice that all laboratory workers must avoid? 19) Before using a water hose on a burning chemical cabinet, a firefighter would visually check that what is posted on the outside of the cabinet? 20) Laboratory personnel wear special monitory badges when working frequently with what hazards? 21) When encountering a person experiencing an electrical shock, the first thing to do is: 22) When a fire is discovered in the laboratory, you should do all of the following except: 23) The acronym RACE is used when encountering a/an: 24) What items found in the laboratory should be securely fastened to a nonmovable object? 25) The most commonly available fire extinguisher in a hospital is: 26) When using a fire extinguisher, which action do you perform first? 27) Variables that are not included in a quality assurance program are what? 28) Clinical laboratory personnel have the least control over what conditions? 29) When you receive a specimen and a requisition form that do not match, you should: 30) When a critical value is obtained in the laboratory: 31) The ability to obtain the published result on a control sample is referred to as: 32) Obtaining the same result after testing the same specimen three times is called test: Centrifuging only uncapped tubes 33) The highest acceptable range for confidence limits in the clinical laboratory is: 34) A procedure with a coefficient of B. ±2 SD Components of the chain of infection Manually recapping needles National Fire Protection Association (NFPA) symbol Radioactive Turn off the circuit breaker for area Leave the door open when evacuating Fire Compressed gas cylinders Type ABC Pull the pin Clinical Pre-examination variables Notify the personnel who collected the specimen The result must be reported to the health-care provider Accuracy Precision Imprecise 2 UA Flashcards Unit 1 variation of 10% is considered: 35) When plotted on a Levy-Jennings chart, a control that has been left on the counter overnight instead of being refrigerated might show a/an: 36) Proficiency testing should be performed: 37) The least regulated level of Clinical Laboratory Improvement Amendments (CLIA) testing categories is: 38) A urinalysis laboratory that subscribes to an external proficiency testing program from which all samples are tested by the supervisor is an example of: 39) True/False: Personnel in the urinalysis laboratory are best protected from blood-borne pathogen exposure when following standard precautions. 40) True/False: It is not necessary to change gloves when performing tasks on the same patient. 41) True/False: OSHA requires employers to provide free immunization for hepatitis B virus (HBV) to workers in urinalysis. 42) True/False: Hands should be washed before and after testing each urine specimen. 43) True/False: A paper towel used to absorb a urine spill is discarded in a biohazard container. 44) True/False: It is acceptable to recap a needle on a syringe containing urine, but not blood. 45) True/False: Only nontoxic chemicals can be pipetted by mouth. 46) True/False: The MSDS should be provided to laboratories by chemical manufacturers or vendors. 47) True or false: Electrical current can pass through glass and wood. 48) True or false: Flammable chemicals must be stored in explosion-proof refrigerators. 49) True or false: When lifting heavy Shift By personnel performing the tests routinely Waived Right things done wrong True False True False False False False True False True True 3 UA Flashcards Unit 1 objects, laboratory workers should bend their knees. 50) Match the following safety hazards with the possible injury: A. Carcinogen exposure B. Strained back C. Viral infection D. Shock 5. Biologic 6. Chemical 7. Electrical 8. Physical 51) State the six components of the chain of infection. 52) Who is responsible for laundering nondisposable lab coats? 53) When gloves are removed, what is the next action taken? 54) What two activities are paper towels used for when washing the hands? 55) Name three blood-borne pathogens. 56) What document does OSHA require all laboratories to have on file when using hazardous chemicals? 57) What are the diamond-shaped, colorcoded labels placed on chemical cabinets in the urinalysis lab called? 58) A laboratory worker who is pregnant should avoid areas designated by what hazard symbol? 59) Describe the type of shoes that should be worn in the laboratory. 60) All of the following are components of normal urine except: A. Urea B. Chloride C. Amino acids D. Creatinine 61) To determine if a specimen is urine, measure the concentrations of: 62) The average daily volume of urine produced by a normal adult is approximately: 63) A person exhibiting oliguria would have a urine volume of: 64) What terms is correctly matched with urine output? 5. 6. 7. 8. C. Viral infection A. Carcinogen exposure D. Shock B. Strained back Infectious agent, reservoir, portal of exit, means of transmission, portal of entry, susceptible host Employer Hand sanitizing Drying the hands and turning off the water HBV, HCV, and HIV Chemical hygiene plan NFPA symbols Radioactive Comfortable, closed-toe C Urea and creatinine 1200 mL 200 to 500 mL Polyuria: 3000 mL in 24 hours 4 UA Flashcards Unit 1 65) The polyuria associated with diabetes mellitus is caused by: 66) Urine from a patient with diabetes insipidus has: 67) A patient with polyuria shows a high specific gravity in the urine. The patient should be evaluated for: 68) Persons taking diuretics can be expected to produce: 69) A urine specimen may be rejected by the laboratory for all of the following reasons except: 70) An unpreserved urine specimen left at room temperature overnight will have decreased: 71) What will be least affected in an unpreserved specimen left at room temperature overnight? 72) Red blood cells will disintegrate more rapidly in urine that is: 73) The primary cause of the changes that take place in unpreserved urine is: 74) What urine chemicals will deteriorate when exposed to light? 75) What is least likely to occur if a urine specimen stands at room temperature for more than 2 hours? 76) A urine specimen for reagent strip glucose analysis can be preserved using all of the following methods except: 77) A urine specimen containing a large amount of precipitated amorphous material may have been preserved using: 78) In the laboratory, the preferred method of urine preservation is: 79) A specimen for routine urinalysis and culture can be preserved using: 80) All of the following are good preservatives of urinary cellular elements except: 81) Before analysis, a refrigerated urine specimen must be: 82) The recommended specimen for routine urinalysis testing is the: 83) The required specimen for The presence of excess glucose in the urine Increased volume and decreased specific gravity Diabetes mellitus Polyuria The container uses a screw-top lid Glucose and ketones Protein Dilute and alkaline Bacterial growth Bilirubin Decreased pH A. Refrigeration B. Boric acid C. Sodium fluoride D. Commercial tablets Refrigeration Refrigeration Boric acid A. Boric acid B. Formalin C. Sodium fluoride D. Thymol Returned to room temperature First morning specimen Timed specimen 5 UA Flashcards Unit 1 quantitative analysis of urinary constituents is the: 84) A first morning specimen is frequently requested to confirm: 85) The first morning specimen from a patient with no history of symptoms for diabetes is positive for glucose. The patient should: 86) The specimen of choice for routine urinalysis is the first morning urine because it: 87) All of the following specimens are acceptable for a urine culture except: 88) Quantitation of a substance that varies with daily activities should be performed on a: 89) Failure to empty the bladder before beginning the collection of a timed urine specimen will: 90) An alternative to the catheterized specimen is the: 91) The least contaminated specimen for bacterial culture is the: 92) The three glass collection is used for the diagnosis of: 93) Documentation of appropriate handling of specimens for drug analysis is provided by the: 94) The liver breaks down protein to form what waste product? 95) An increase in urine production during the night is described as: 96) Where should labels on urine specimen containers be placed? 97) Increased turbidity in urine stored at room temperature is usually caused by: 98) What is the maximum length of time a urine specimen can remain unpreserved at room temperature before testing? 99) Which specimen(s) from a three glass collection do(es) not have to be examined microscopically? 100) The temperature of a specimen for drug testing is 25oC when measured within 4 minutes of collection. Orthostatic proteinuria Be asked to collect the second morning specimen Is more concentrated to better detect abnormalities A. Catheterized specimen B. Timed specimen C. Suprapubic aspiration D. Midstream clean-catch specimen 24-hour specimen Cause falsely increased results Midstream clean-catch specimen Suprapubic aspiration Prostate infection Chain of custody form Urea Nocturia Container Bacterial growth 2 hours #2 False-negative 6 UA Flashcards Unit 1 101) The second sample of a three glass collection has a positive urine culture. 102) A patient is deprived of fluids during a 6-hour timed urine collection 103) Aliquots from 24-hour specimens are being obtained before measuring and mixing the sample. 104) True or False: Urine contains organic and inorganic chemicals that can vary with body metabolic functions. 105) True or False: Physicians performing urinalysis can determine whether a specimen is urine from the presence of formed elements. 106) True or False: Dietary intake does not influence urine volume. False-positive 107) True or False: Polydipsia is a symptom of both diabetes mellitus and diabetes insipidus. 108) True or False: A urine specimen label should include the date and time of collection. True 109) True or False: Urine that remains unpreserved at room temperature will show an increase in the concentrations of nitrate, glucose, and white blood cells. 110) True or False: specimen delivered to the laboratory in a gray-top Vacutainer is acceptable for urinalysis. 111) True or False: A urine bacterial culture should not be performed on a catheterized specimen. 112) Normal functions of the kidney include all of the following except: False 113) The approximate number of nephrons contained in each kidney is: 114) Increased production of aldosterone causes: 115) The primary chemical affected by the renin-angiotensin-aldosterone system is: False-negative False-negative True False False True False False A. Regulating body hydration B. Elimination of nitrogenous wastes C. Regulating electrolyte balance D. Elimination of serum proteins 1,000,000 Increased plasma sodium levels Sodium 7 UA Flashcards Unit 1 116) The specific gravity of the glomerular ultrafiltrate is: 117) The enzyme renin is produced by the kidney: 118) Decreased production of aldosterone: 119) Production of antidiuretic hormone is controlled by the: 120) All of the following are endogenous clearance test substances except: 1.010 121) If a substance is completely filtered by the glomerulus and then completely reabsorbed by the tubules, the clearance of that substance will be: 122) The most routinely used laboratory method for measuring the glomerular filtration rate is the: 123) For accurate evaluation of renal tubular concentrating ability, patient preparation should include: 124) A technical error that could cause a discrepancy between freezing-point and vapor-pressure osmometry readings is: 125) What tests provides information similar to specific gravity? 126) The PAH test is used to measure: 127) What is not associated with the elimination of hydrogen ions? 128) Tests to measure the tubular secretion of hydrogen ions include all of the following except: Zero In response to low plasma sodium levels Produces a high urine volume State of body hydration A. Urea B. Creatinine C. Inulin D. Beta2 microglobulin Estimated glomerular filtration rate Fluid deprivation Failure to separate cells and serum Osmolality Renal blood flow Protein A. pH B. Titratable acidity C. Urinary bicarbonate D. Urinary ammonia 129) Following administration of oral Urine with a high pH ammonium chloride, a patient with renal tubular acidosis will produce: 130) What clearance substances does not Cystatin C require urine collection? 131) What is the physical property Dew point temperature measured by a vapor-pressure osmometer? A laboratory supervisor is authorized to purchase a new osmometer. The supervisor must decide between a freezing-point and a vapor-pressure model. 132) Based on the information provided Vapor-pressure above if this is a pediatric hospital, 8 UA Flashcards Unit 1 which model is better? 133) Using the information provided above, which model is more likely to be affected by technical errors? 134) Using the information provided above, which model is affected by lipemic serum but not elevated ethanol levels? True or False 135) The afferent and efferent arterioles have the ability to vary in size. 136) True or False Blood pressure within the glomerulus varies directly with systemic blood pressure. 137) True or False A decrease in plasma sodium produces an increase in blood volume. 138) True or False? The filtrate leaving the ascending loop of Henle is highly concentrated. 139) True or False? A substance that is not filtered by the glomerulus will not be found in the urine. 140) True or False? Hydrogen ions are filtered by the glomerulus and reabsorbed and secreted by the renal tubules. 141) True or False? An increase in the plasma level of beta2 microglobulin correlates with decreased glomerular filtration. 142) The primary pigment responsible for normal urine color is: Vapor-pressure Freezing-point True False False False False True True Urochrome 143) A dark yellow urine producing yellow foam may contain: Bilirubin 144) What urine colors and causes match? Black—melanin 145) The color of a urine specimen containing blood can be attributed to all of the following except the: A. Amount of blood B. Blood type of patient C. pH of the urine D. Length of contact Homogentisic acid 146) A urine specimen that turns black after standing may contain: 147) What specific gravity readings correlates with a pale yellow urine? 1.005 9 UA Flashcards Unit 1 148) Specimens that contain intact red blood cells can be visually distinguished from specimens that contain hemoglobin because: 149) Urine from a patient diagnosed with hepatitis will appear: 150) The pigment responsible for a pink precipitate in refrigerated urine is: 151) The presence of a white precipitate in freshly voided urine can be caused by: 152) The addition of dilute acetic acid to a cloudy urine specimen will dissolve: 153) Slightly warming a turbid urine specimen may dissolve: 154) An antidiuretic hormone deficiency is associated with a: 155) The specific gravity of urine is directly proportional to its: 156) A patient that has been diagnosed with diabetes mellitus will produce urine with: Intact red blood cells produce a cloudy specimen 157) A urine with the same specific gravity as the ultrafiltrate is called: 158) Specific gravity is a measure of: 159) What statements concerning measurement of specific gravity by refractometer is not true? 160) The calibration of the refractometer can be quality-controlled using all of the following except: Isosthenuric 161) Results of a specific gravity reading obtained by refractometer in the urology clinic do not agree with the readings obtained by the laboratory’s automated reagent strip reader. The laboratory should: 162) Bacterial decomposition of urea produces urine that has an odor resembling Amber Uroerythrin Amorphous phosphates in alkaline urine Amorphous phosphate Amorphous urates Low specific gravity Dissolved solids Increased volume and increased specific gravity Density The refractometer must be calibrated after every specimen. A. Distilled water B. 5% NaCl C. 9% sucrose D. Commercial controls Report the results from the reagent strip reader Ammonia A urine turns black after standing, develops a cloudy white precipitate, and has a specific gravity of 1.010. 163) Based on the information provided above, the primary concern about this specimen is: 164) Based on the information provided above,, the most likely cause of the black Color Homogentisic acid 10 UA Flashcards Unit 1 color in this specimen is: 165) Based on the information provided, the most probable cause of the white precipitate is: 166) Based on the information provided above,, the primary basis for the changes that took place in this specimen is: 167) True or False? A urine specimen that remains at room temperature for several hours may develop a darker yellow color. 168) T/ F? A pale yellow urine is a primary indication of impaired renal function. 169) True or False? Clear red urine and red plasma are associated with myoglobinuria Amorphous phosphates 170) True or False? Collection of a midstream clean catch specimen can affect the clarity of a urine specimen. 171) True or False? A clear yellow urine will not contain any pathologically significant constituents. 172) True or False? Urine specific gravity can be measured by both physical and chemical methods. 173) True or False? Urine specific gravity is equally influenced by the presence of glucose and sodium. 174) True or False? The density of a urine specimen can affect the frequency of a sound wave 175) True or False? A supervisor should be concerned if a specific gravity reading of 1.008 is reported on a turbid urine specimen 176) Acceptable or unacceptable for routine urinalysis testing? A clear, pale yellow specimen with a specific gravity of 1.030. 177) Acceptable or unacceptable for routine urinalysis testing? A cloudy, brown- black urine with a positive test for blood and a strong odor of ammonia 178) Acceptable or unacceptable for routine urinalysis testing? A hazy, yellow urine that produces a noticeable amount of white foam 179) Acceptable or unacceptable for routine True Exposure over time to ambient air True False False False True False True False Acceptable Unacceptable Acceptable Acceptable 11 UA Flashcards Unit 1 urinalysis testing? A port wine colored specimen with a negative test for blood 180) Acceptable or unacceptable for routine urinalysis testing? A pale yellow urine with a noticeable odor of bleach 181) Clinically significant or non-significant urine turbidity? White blood cells 182) Clinically significant or non-significant urine turbidity? Radiographic contrast media 183) Clinically significant or non-significant urine turbidity? Squamous epithelial cells 184) Clinically significant or non-significant urine turbidity? Bacteria 185) Clinically significant or non-significant urine turbidity? Lipids 186) Clinically significant or non-significant urine turbidity? Amorphous urates 187) Melanin causes what color urine? 188) Clorets cause what color urine? 189) A patient with polydipsia has what color urine? 190) Porphobiliogen causes what color urine? 191) Pseudomonas infection causes what color urine? 192) Beets cause what color urine? 193) Bilirubin causes what color urine? 194) Normal urine has what odor? 195) Bacterial infection causes what odor in the urine? 196) Diabetes mellitus causes what odor in the urine? 197) Proper care of reagent strips includes all of the following except: 198) Quality control on reagent strips must be performed whenever a/an: 199) The reagent strip reaction that should be read last is the: 200) Failure to blot the edge of the reagent strip may result in errors in color Unacceptable Significant urine turbidity Non-significant urine turbidity Non-significant Significant Significant Non-significant Black Green Pale yellow Red Green Red Dark yellow Aromatic Ammonia Fruity A. Checking the expiration date B. Storing in a clear container C. Preventing exposure to toxic fumes D. Storing with a desiccant New bottle of strips is opened Leukocyte esterase Runover 12 UA Flashcards Unit 1 interpretation caused by: 201) Reagent strip chemical tests may be inaccurate if the specimen is: 202) When performing reagent strip quality control, the: 203) All of the following will produce an alkaline urine except: 204) The normal range of urine pH is: 205) A urine specimen with a pH of 9.0 indicates that the patient should be: 206) Urinary pH provides valuable information for the: 207) A urine with a high pH reading can contain a: 208) What results is not typical of a urine specimen from an uncontrolled diabetic? 209) The protein section of the reagent strip is most sensitive to: 210) When using the reagent strip microalbumin method, false-negative results may occur in the presence of: 211) To detect the presence of early renal disease, diabetic patients are tested for: 212) A possible cause of postrenal proteinuria is: 213) All of the following descriptions apply to orthostatic proteinuria except: 214) All of the following can be used to detect the presence of microalbuminuria except the: 215) The microalbumin test should be performed on: 216) Following a pre-hospital rotation physical, a medical laboratory science student is requested to collect a first morning urine specimen. The physician is checking for: 217) The albumin to creatinine ratio may be elevated in patients whose urine contains: 218) The pseudoperoxidase reaction is the principle for the reagent strip test(s) for: Tested immediately after refrigeration Positive readings should match the reference value by plus or minus one color block A. Lettuce B. Cranberry juice C. Green beans D. Tomatoes 4.5 to 8.0 Asked to collect a new specimen Identification of urinary crystals Low concentration of hydrogen ions High pH Albumin Highly dilute urine Microalbuminuria Prostatitis A. Most commonly appears in young adults B. Usually occurs without apparent disease C. Urinary proteins are excreted only when the patient is lying down D. Is considered to be a functional, transitory proteinuria A. Multistix Pro B. Sulfosalicylic acid (SSA) test C. Micral-Test D. Clinitek 50 A first morning collection Orthostatic proteinuria Glucose Blood 13 UA Flashcards Unit 1 219) Microalbumin tests are frequently used to screen patients with: 220) A random urine specimen and plasma glucose test that are to be drawn and collected at the same time can be used to confirm: 221) The appearance of glucose in the urine of a patient with an elevated blood sugar indicates: 222) Pediatric urine specimens are additionally tested for the presence of: 223) A urine specimen is analyzed for glucose by a glucose oxidase reagent strip and a copper reduction test. If both results are positive, what interpretations is correct? 224) A laboratory error that can result in an infant developing severe mental retardation could be attributed to failure to perform a/an: 225) All of the following may interfere with glucose detection in a urine specimen except: 226) Glucosuria not accompanied by hyperglycemia is seen in patients with: 227) What statements is/are correct for glucose testing by reagent strip? I. Glucose oxidase reacts with glucose in the urine. II. Non-glucose–reducing substances fail to react. III. Ascorbic acid may cause a falsenegative reaction. IV. Hydrogen peroxide and peroxidase react to oxidize a chromogen. 228) Galactose will react with: 229) While performing a Clinitest, you observe that the color changes rapidly from blue to orange and then back to blue. You should: 230) The ketones that are produced in normal adult metabolism include all of the following except: 231) What will not cause ketonuria? 232) Excessive fat metabolism is indicated by Diabetes mellitus Nonpathogenic glycosuria Diabetes mellitus Galactose using Clinitest Glucose only is present Clinitest A. Galactose B. Ascorbic acid C. The sample sits at room temperature for 4 hours D. All of the above Renal disease I, II, III, and IV Clinitest but not Chemstrip Repeat the test using fewer drops of urine to check for “pass through” A. Acetone B. Phenylketones C. Acetoacetic acid D. Beta-hydroxybutyric acid Increased metabolism of carbohydrates Ketones 14 UA Flashcards Unit 1 the urinary presence of: 233) A urine sample that tests positive for ketones and negative for glucose is most likely from a patient suffering from: 234) Myoglobinuria may be caused by: 235) Ammonium sulfate is added to a red colored urine. The urine had a positive reaction for blood, but there were no red blood cells in the sediment. After centrifugation, the sedimented ammonium sulfate is red. The abnormal color is caused by: 236) The detection of hemosiderin in the urine can be associated with: 237) A spotted reaction on the reagent strip reaction for blood can indicate: 238) A reagent strip test for blood is reported positive. No red blood cells are seen on the microscopic examination. The patient’s condition is called: 239) What is not true about the Ictotest? 240) Urobilinogen is formed from the: 241) Specimens for urobilinogen testing are collected between 2 p.m. and 4 p.m. because: 242) What can produce a negative nitrite test in the presence of significant bacteriuria? 243) What will be detected by the reagent strip nitrite reaction? 244) All of the following will produce a positive leukocyte esterase (LE) reaction except: 245) Major advantages of the leukocyte esterase reagent strip test include all of the following except: 246) The cells most frequently associated with urinary tract infection are: 247) A false-negative LE reaction may be caused by: 248) The method of choice for performing a specific gravity following administration of radiographic dye is: Starvation A “crushing” injury Hemoglobin Hemoglobinuria Hematuria Hemoglobinuria It is less sensitive than the reagent strip test. Reduction of bilirubin by intestinal bacteria An alkaline tide occurs following lunch The presence of many non-nitrate reducing bacteria Escherichia coli A. Monocytes B. Trichomonas C. Neutrophils D. Lymphocytes A. It will detect the presence of lysed leukocytes B. It can be used to screen specimens before bacterial culturing C. It is a more standardized method for detecting leukocytes than the microscopic method D. It will accurately quantitate the leukocytes present Neutrophils Failure to wait 2 minutes to read the reaction Reagent strip 15 UA Flashcards Unit 1 249) A dark blue color in the reagent strip pad for specific gravity indicates: 250) The reagent strip reaction most critically affected by failure to blot the strip is the: 251) 86. What is not affected by increased intake of ascorbic acid? 252) A burn injury may occur if incorrect technique is used when performing the: A low specific gravity 253) The urinalysis result most closely associated with renal disease is a positive: 254) State the most probable cause for each of the following scenarios: A student is having difficulty interpreting the reagent strip color reactions on a thick orange specimen. 255) A laboratory that routinely screens all infants with the Clinitest is accused of missing a case of galactosuria. 256) Excessive fizzing is observed when using Clinitest tablets. 257) A vegetarian consistently has falsepositive readings for blood on routine specimens. 258) A test on a yellow-green specimen from a jaundiced patient is negative for bilirubin. 259) A student reports a positive urobilinogen using Multistix and a negative urobilinogen using Chemstrip on the same specimen. 260) What substances recirculates to the liver? 261) The substance converted to urobilin is: 262) The substance bound to albumin is: 263) The substance produced in the liver is: 264) The substance that produces the brown color associated with normal feces is: 265) Reagent strips provide quantitative urine chemistry results. 266) The Multistix and Chemstrip color charts are interchangeable. 267) A person with respiratory acidosis is expected to have a low urine pH. 268) Orthostatic proteinuria is a form of renal proteinuria. 269) Myoglobin is removed from the blood more rapidly than hemoglobin. 270) The nitrite test is not reliable unless Protein pH Ketones Clinitest Phenazopyridium “Pass through” was not observed Tablets deteriorated Vegetable peroxidase Bilirubin oxidized to biliverdin Outdated reagent strip Urobilinogen Conjugated bilirubin Unconjugated bilirubin Conjugated bilirubin Stercobilinogen False False True True True False 16 UA Flashcards Unit 1 specimens are collected using the midstream clean-catch technique. 271) When performing a reagent strip specific gravity on an alkaline urine, 0.005 should be subtracted from the reading. 272) Ascorbic acid will bind with diazonium salts. 273) The number of fields that should be examined when quantitating urinary sediment constituents is: 274) A lipid droplet that does not stain with Sudan III may be composed of: 275) A urine specimen is referred for cytodiagnostic urine testing to detect the presence of: 276) To standardize the sediment concentration for microscopic analysis one must: 277) The purpose of scanning the perimeter of urine sediment placed under a conventional glass slide is to: 278) All of the following are reported as the quantity per high-power field except: 279) The most probable structures to be stained by the Prussian blue stain are: 280) The purpose of including glucose as a significant chemical parameter by a laboratory that performs macroscopic screening is to check for presence of: 281) Calculation of the number of RBCs per milliliter of urine requires knowledge of all of the following except the: 282) A medical laboratory science student consistently obtains lower RBC counts than the instructor. A possible reason for this might be: 283) Centrifugation of less than the recommended 12 mL of urine for the microscopic examination will: 284) Substances found in the urinary sediment that can be confirmed using False True 10 Cholesterol Malignant cells Use only the urine tubes and pipettes for a single commercial system Detect the presence of casts A. Casts B. Red blood cells (RBCs) C. White blood cells (WBCs) D. Bacteria Renal tubular epithelial cells Candida albicans A. Number of high-power fields per milliliter of urine B. Speed of centrifugation C. Number of high-power fields per viewing area D. Area of a high-power field Failure to completely resuspend the sedimented specimen Decrease the number of cellular elements A. WBCs bodies 17 UA Flashcards Unit 1 polarized light are: 285) Using polarized microscopy, what is/are birefringent? 286) Identification of oval fat bodies can be verified using: 287) Using a bright-field microscope, the final magnification of a high-power field is: 288) To detect the presence of casts, the sediment is examined using: 289) Optimal viewing is obtained by performing Köhler illumination adjustment to the: 290) To increase the probability of detecting urine sediment constituents that have a low refractive index, clinical laboratories often use: 291) The presence of crenated RBCs in the urine sediment is associated with: 292) Dilute alkaline urine should be examined carefully for the presence of: 293) A patient with severe back pain and 15 to 20 RBCs/hpf in the urine sediment may have: 294) Differentiation among RBCs, yeast, and oil droplets may be accomplished by all of the following except: 295) Ghost RBCs most frequently occur with a urine specimen that exhibits the following: 296) The presence of hypochromic, irregularly shaped RBCs in the urine sediment can indicate: 297) Glitter cell is a term used to describe a specific type of: 298) An increase in urinary WBCs is called: 299) Urine sediments containing increased WBCs should be observed closely for the presence of: 300) Eosinophils are found in the urine in cases of: 301) Leukocytes that stain pale blue with Sternheimer-Malbin stain and exhibit brownian movement are: 302) Oval fat bodies are: 303) The type of cells that line the bladder and ureters are called: 304) Initial microscopic focusing on the D. Lipids Cholesterol Polarized light 400X Reduced light under low power Condenser Phase-contrast microscopy Hypersthenuria Ghost RBCs Renal calculi A. Observation of budding in yeast cells B. Increased refractility of oil droplets C. Lysis of yeast cells by acetic acid D. Lysis of RBCs by acetic acid High pH, low specific gravity Glomerular bleeding Neutrophil Pyuria Bacteria Acute interstitial nephritis Glitter cells Renal tubular epithelial cells that contain lipids Transitional Squamous epithelial cells 18 UA Flashcards Unit 1 urinary sediment is frequently performed by referencing: 305) In ascending order, the location of epithelial cells in the urinary tract is: 306) Clue cells are derived from: 307) The organisms attached to a clue cell are: 308) Urothelial cells routinely occur in all of the following shapes except: 309) What cells found in increased numbers in the urine sediment is only indicative of nephron damage? 310) Collection of a midstream clean-catch specimen will alleviate contamination by: 311) What cells can both be found in both a vaginal wet prep and in urine sediment? Squamous, transitional, renal tubular Squamous epithelial cells Gardnerella vaginalis A. Spherical B. Cylindroid C. Polyhedral D. Caudate Renal tubular cells Squamous epithelial cells Yeast cell and clue cell 312) Spherical transitional epithelial cells can be differentiated from renal tubular epithelial cells by observing the: 313) The finding of renal tubular epithelial cells containing yellow-brown granules correlates with a positive reagent strip test for: 314) The primary factor that favors the formation of urinary casts is: 315) The major constituent of urinary casts is: Centrally located nucleus in transitional cells 316) Waxy casts are most easily differentiated from hyaline casts by their: 317) Urinary casts are formed in the: 318) What elements would most likely be found in an acidic concentrated urine that contains protein? 319) Sediment constituents that are used to differentiate between upper and lower urinary tract infections are: 320) To differentiate a bacterial cast from a granular cast, a clinical laboratory scientist could: 321) The type of cast most closely associated with tubular damage is the: 322) The only type of cast capable of polarization is the: 323) Broad casts may form as a result of: 324) The finding of increased hyaline and granular casts in the urine of an otherwise Refractivity Blood Urinary stasis Uromodulin protein Distal and collecting tubules Casts WBC casts Perform a Gram stain Epithelial cell cast Fatty cast . Extreme urinary stasis Recent strenuous exercise 19 UA Flashcards Unit 1 healthy person may be the result of: 325) Hyaline casts may degenerate into: 326) Waxy casts can be found in the urine sediment: 327) The urinary sediment constituent most closely associated with bleeding within the nephron is the: 328) What differentiates a waxy cast from a fiber most effectively? 329) All of the following may be seen in the urine following strenuous exercise except: 330) To distinguish a cellular cast from a clump of cells, the clinical laboratory scientist should: 331) Granular casts present in the urine following strenuous exercise can: 332) All of the following are associated with severe urinary stasis except: 333) Identification of urinary crystals is based on shape and: 334) Urinary crystals that appear yellow to reddish-brown are: 335) To dissolve amorphous urates, you could: 336) Nonpathogenic or “normal” crystals found in acidic urine include: Waxy casts In patients with renal failure RBC cast Waxy casts do not polarize light, and fibers do. A. Protein B. Glucose C. Hyaline casts D. Granular casts Look carefully for a cast matrix Contain cellular lysosomes A. Granular casts B. Waxy casts C. WBC casts D. Broad casts Urine pH and crystal solubility Uric acid Warm the specimen to body temperature Calcium oxalate, uric acid, amorphous urates 337) All of the following crystals can be found in acid urine except: A. Cholesterol B. Tyrosine C. Cystine D. Ammonium biurate 338) Abnormal crystals are most frequently seen in a urine that is: 339) Information that aids in the identification of crystals includes all of the following except: Acid 340) What crystals occurs in two very distinct forms? 341) Nonpathogenic or “normal” crystals found in alkaline urine include: A. Urine temperature B. Urine pH C. Crystal solubility D. Crystal birefringence Calcium oxalate Triple phosphate, calcium carbonate, ammonium biurate 20 UA Flashcards Unit 1 342) Crystals found in the urine that are associated with pathogenic disease include: 343) What crystals is associated with ethylene glycol ingestion? 344) A urine specimen refrigerated overnight is cloudy and has a pH of 6. The turbidity is probably due to: 345) All of the following affect the formation of crystals except: 346) Cystine crystals are often confused with: 347) Formation of crystals due to medications is most frequently caused by 348) Calcium carbonate crystals can be distinguished from bacteria by: 349) What results should have testing repeated? 350) The significance of seeing bacteria in the urine sediment is increased when: 351) Yeast may appear in the urine sediment in all of the following forms except: 352) Schistosoma haematobium would most likely be found in the urine from a: 353) Motility by what is most noticeable during the urine sediment examination? 354) Urine sediment artifacts frequently differ from true sediment constituents by their: 355) Under polarized light, all of the following will exhibit the Maltese cross formation except: 356) In an unpreserved and old urine specimen, there could be difficulty differentiating between bacteria and: 357) What is most likely to be found in the urine of a diabetic patient? 358) Specimens containing mucus may be erroneously reported as containing: 359) Enhance nuclear detail. 360) Stain oval fat bodies. 361) Stain eosinophils. 362) Stain hemosiderin granules. 363) True/False To adjust the intensity of light in a bright-field microscope, the Leucine and tyrosine Calcium oxalate monohydrate Amorphous urates A. Urine specific gravity B. Urine pH C. Urinary casts D. Urine temperature Uric acid crystals Inadequate hydration Adding acetic acid pH 7.0 with uric acid crystals WBCs are present A. Mycelial B. Biconcave C. Oval D. Budding ovals Foreign-service employee Trichomonas vaginalis Refractility A. Starch granules B. Oval fat bodies C. Pollen grains D. Fatty casts Amorphous phosphates Candida albicans Hyaline casts Toluidine blue Sudan III Hansel stain Prussian blue False 21 UA Flashcards Unit 1 condenser should be raised or lowered. 364) True/False When changing magnification using a parfocal microscope, focusing is performed using the coarse adjustment knob. 365) True/False In the urinalysis laboratory, a bright-field microscope can be converted to a polarizing microscope. 366) True/False The finding of increased urinary WBCs is not significant unless increased bacteria are also present. 367) True/False Renal tubular epithelial cells from the distal convoluted tubule are smaller than those from the proximal convoluted tubule. 368) True/False A structure resembling a cast but having a tapered end should not be reported as a cast. 369) True/False WBC casts should always be accompanied by significant bacteriuria. 370) True/False To be considered significant, yeast cells in the urine sediment should be accompanied by leukocytes. 371) True/False Trichomonas vaginalis is not found in urine from male patients. 372) Choose the correct microscope part (1-5) needed to perform the following functions (A-E) 1. Focus light on the specimen 2. Hold the objectives 3. Increase objective resolution 4. Control light intensity 5. Regulate interpupillary distance A. Condenser B. Oculars C. Diopter adjustment knob D. Rheostat E. Nose piece 373) Match the description (A-E) for the following urine crystals (1-3): 1. Ammonium biurate 2. Calcium carbonate 3. Triple phosphate A. Thorny apple B. Coffin lid C. Notched corners D. Hexagonal E. Dumbbell False True False True False False True False 1. A 2. E 3. B 4. D 5. C 1. A 2. E 3. B 22 UA Flashcards Unit 1 374) Match the following urine crystals (1-5) with their description (A-E): 1. 2. 3. 4. 5. Ammonium biurate Calcium carbonate Triple phosphate Cystine Cholesterol A. Thorny apple B. Coffin lid C. Notched corners D. Hexagonal E. Dumbbell 375) State if a urinalysis supervisor would be concerned or not concerned about the following results: Enterobius vermicularis and waxy casts in a cloudy specimen from a pediatric patient 376) Concerned or not concerned? RBC casts in a specimen with a negative reagent strip test for blood 377) Concerned or not concerned? Triple phosphate and ammonium biurate crystals in a specimen with a pH of 8.0 378) Concerned or not concerned? Candida albicans and leukocytes in a specimen with a negative nitrite test 379) Concerned or not concerned? 2–3 granular casts/lpf in a refrigerated specimen containing many amorphous crystals 380) Concerned or not concerned? Many budding yeasts in a clear, red specimen from a bedridden, diabetic patient 1. Ammonium biurate A 2. Calcium carbonate E 3. Triple phosphate B 4. Cystine D 5. Cholesterol C Concerned Concerned Not concerned Not concerned Concerned Not concerned 23