Updated Oct 08, 2015
RPPA platform: Publications in peer-reviewed journals
1. Michaut M*, Chin SF*, Majewski I*, Severson TM*, Bismeijer T*, De Koning L*, Peeters JK*,
Schouten PC, Rueda OM, Bosma AJ, Tarrant F, Fan Y, He B, Xue Z, Mittempergher L, Kluin RJC,
Heijmans J, Snel M, Pereira B, Schlicker A, Provenzano E, Raza Ali H, Gaber A, O'Hurley G, Kay
E, Lehn S, Muris JJF, Wesseling J, Sammut SJ, Bardwell HA, Barbet AS, Bard F, Lecerf C, Vis DJ,
Benes CH, McDermott U, Garnett MJ, Simon IM, Jirström K, Dubois T, Linn S, Gallagher WM,
Wessels LFA, Caldas C, Bernards R ; Integration of genomic, transcriptomic and proteomic
data identifies two biologically distinct subtypes of invasive lobular breast cancer ; Nature
Scientific Reports, in press (*co-first authors)
2. Baldeyron C, Tesson B, Némati F, Koundrioukoff S, Brisson A, Saliba E, De Koning L, Gentien
D, Decaudin D, Debatisse M, Depil S, Cruzalegui F, Pierré A, Roman-Roman S, Tucker GC,
Dubois T ; TIPIN depletion leads to apoptosis in breast cancer cells, Mol Oncol. 2015 May 9.
pii: S1574-7891(15)00098-8
3. Rondeau S, Vacher S, De Koning L, Briaux A, Schnitzler A, Chemlali W, Callens C, Lidereau R,
Bieche I; ATM has a major role in the double-strand break repair pathway dysregulation in
sporadic breast carcinomas and is an independent prognostic marker at both mRNA and
protein levels; Br J Cancer. 2015 Mar 17;112(6)
4. Akbani R, Becker KF, Carragher N, Goldstein T, de Koning L, Korf U, Liotta L, Mills GB,
Nishizuka SS, Pawlak M, Petricoin EF 3rd, Pollard HB, Serrels B, Zhu J.; Realizing the promise
of reverse phase protein arrays for clinical, translational, and basic research: a workshop
report: the RPPA (Reverse Phase Protein Array) society; Mol Cell Proteomics. 2014 Jul;13(7)
5. Boin A, Couvelard A, Couderc C, Brito I, Filipescu D, Kalamarides M, Bedossa P, De Koning L,
Danelsky C, Dubois T, Hupé P, Louvard D, Lallemand D.; Proteomic screening identifies a YAPdriven signaling network linked to tumor cell proliferation in human schwannomas; Neuro
Oncol. 2014 Sep;16(9)
6. Broutin S, Commo F, De Koning L, Marty-Prouvost B, Lacroix L, Talbot M, Caillou B, Dubois T,
Ryan AJ, Dupuy C, Schlumberger M, Bidart JM.; Changes in signaling pathways induced by
vandetanib in a human medullary thyroid carcinoma model, as analyzed by reverse phase
protein array.; Thyroid. 2014 Jan;24(1)
7. Calderaro J, Rebouissou S, de Koning L, Masmoudi A, Hérault A, Dubois T, Maille P, Soyeux P,
Sibony M, de la Taille A, Vordos D, Lebret T, Radvanyi F, Allory Y. ; PI3K/AKT pathway
activation in bladder carcinogenesis.; Int J Cancer. 2014 Apr 15;134(8)
8. Maire V, Baldeyron C, Richardson M, Tesson B, Vincent-Salomon A, Gravier E, MartyProuvost B, De Koning L, Rigaill G, Dumont A, Gentien D, Barillot E, Roman-Roman S, Depil S,
Cruzalegui F, Pierré A, Tucker GC, Dubois T. ; TTK/hMPS1 is an attractive therapeutic target
for triple-negative breast cancer.; PLoS One. 2013 May 20;8(5)
9. Laurent C, Gentien D, Piperno-Neumann S, Némati F, Nicolas A, Tesson B, Desjardins L,
Mariani P, Rapinat A, Sastre-Garau X, Couturier J, Hupé P, de Koning L, Dubois T, RomanRoman S, Stern MH, Barillot E, Harbour JW, Saule S, Decaudin D.; Patient-derived xenografts
recapitulate molecular features of human uveal melanomas; Mol Oncol. 2013 Jun;7(3)
10. Tlili A, Jacobs F, de Koning L, Mohamed S, Bui LC, Dairou J, Belin N, Ducros V, Dubois T, Paul
JL, Delabar JM, De Geest B, Janel N.; Hepatocyte-specific Dyrk1a gene transfer rescues
plasma apolipoprotein A-I levels and aortic Akt/GSK3 pathways in hyperhomocysteinemic
mice; Biochim Biophys Acta. 2013 Jun;1832(6)
11. Maire V, Némati F, Richardson M, Vincent-Salomon A, Tesson B, Rigaill G, Gravier E, MartyProuvost B, De Koning L, Lang G, Gentien D, Dumont A, Barillot E, Marangoni E, Decaudin D,
Roman-Roman S, Pierré A, Cruzalegui F, Depil S, Tucker GC, Dubois T; Polo-like kinase 1: a
potential therapeutic option in combination with conventional chemotherapy for the
management of patients with triple-negative breast cancer; Cancer Res. 2013 Jan 15;73(2)
12. Scholl SM, Kamal M, De Koning L, Kereszt A, Jordanova ES, Ungureanu S, Berns E, Sastre X.;
HPV pathway profiling: HPV related cervical dysplasia and carcinoma studies; Curr Pharm
Des. 2013;19(8)
13. Troncale S, Barbet A, Coulibaly L, Henry E, He B, Barillot E, Dubois T, Hupé P, de Koning L.;
NormaCurve: a SuperCurve-based method that simultaneously quantifies and normalizes
reverse phase protein array data; PLoS One. 2012;7(6)
14. Quanz M, Herbette A, Sayarath M, de Koning L, Dubois T, Sun JS, Dutreix M.; Heat shock
protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in
repair foci; J Biol Chem. 2012 Mar 16;287(12)